Aliases for DGAT2 Gene
Aliases for DGAT2 Gene
External Ids for DGAT2 Gene
- HGNC: 16940
- Entrez Gene: 84649
- Ensembl: ENSG00000062282
- OMIM: 606983
- UniProtKB: Q96PD7
Previous GeneCards Identifiers for DGAT2 Gene
- GC11P077806
- GC11P077018
- GC11P075693
- GC11P075206
- GC11P075157
- GC11P075479
- GC11P071776
Summaries for DGAT2 Gene
-
This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for DGAT2 Gene
DGAT2 (Diacylglycerol O-Acyltransferase 2) is a Protein Coding gene. Diseases associated with DGAT2 include Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 Due To Dgat2 Mutation and Pellagra. Among its related pathways are Fat digestion and absorption and Metabolism. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and 2-acylglycerol O-acyltransferase activity. An important paralog of this gene is DGAT2L6.
UniProtKB/Swiss-Prot for DGAT2 Gene
-
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).
-
Diacylglycerol O-Acyltransferases (DGATs), EC 2.3.1.20, are enzymes that catalyze the final step of triglyceride (TG) synthesis, the covalent attachment of fatty acyl-CoA and diacylglycerol (DAG). There have been two DGAT isoforms identified to date, DGAT1 and DGAT2.
Additional gene information for DGAT2 Gene
- Monarch Initiative
- Search for DGAT2 at DataMed
- Search for DGAT2 at HumanCyc
No data available for CIViC summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DGAT2 Gene
Genomics for DGAT2 Gene
GeneHancer (GH) Regulatory Elements for DGAT2 Gene
Promoters and enhancers for DGAT2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around DGAT2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the DGAT2 gene promoter:
Regulatory Element Products
Genomic Locations for DGAT2 Gene
Genomic Locations for DGAT2 Gene
- chr11:75,759,512-75,801,536
- (GRCh38/hg38)
- Size:
- 42,025 bases
- Orientation:
- Plus strand
- chr11:75,470,557-75,512,579
- (GRCh37/hg19)
Genomic View for DGAT2 Gene
Genes around DGAT2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.5 by Ensembl
- 11q13.5 by Entrez Gene
- 11q13.5 by HGNC
DGAT2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DGAT2 Gene
Proteins for DGAT2 Gene
-
Protein details for DGAT2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96PD7-DGAT2_HUMAN
- Recommended name:
- Diacylglycerol O-acyltransferase 2
- Protein Accession:
- Q96PD7
- A6ND76
- Q5U810
- Q68CL3
- Q68DJ0
- Q8NDB7
- Q96BS0
- Q9BYE5
Protein attributes for DGAT2 Gene
- Size:
- 388 amino acids
- Molecular mass:
- 43831 Da
- Quaternary structure:
-
- Forms multimeric complexes consisting of several DGAT2 subunits.
- SequenceCaution:
-
- Sequence=BAD38635.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD38961.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for DGAT2 Gene
Selected DME Specific Peptides for DGAT2 Gene
- Q96PD7:
-
- QKKFQKY
- LQVISVLQ
- VSKKFPGI
- GGAAESL
- YSFGENEVYKQ
- VLQWVLSFL
- LATLAGNFR
- WVRNWAVWRYFRDYFP
- PITTVVG
Post-translational modifications for DGAT2 Gene
No Post-translational modifications
Other Protein References for DGAT2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for DGAT2 (DGAT2)
-
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-
Abcam antibodies for DGAT2
-
Cloud-Clone Corp. Antibodies for DGAT2
- Invitrogen Antibodies for DGAT2
- Search GeneTex for Antibodies for DGAT2
-
Santa Cruz Biotechnology (SCBT) Antibodies for DGAT2
Protein Products
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- Origene Custom Protein Services for DGAT2
-
Cloud-Clone Corp. Proteins for DGAT2
- antibodies-online: Search results for 6 available DGAT2 Proteins ranked by validation data
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-
Quality Products:
- Search GeneTex for Proteins for DGAT2
-
Abcam proteins for DGAT2
Assay Products
-
Cloud-Clone Corp. Assay Kits for DGAT2
- antibodies-online: Search results for 5 available DGAT2 Elisa Kits ranked by validation data
- Compare Top DGAT2 Elisa Kits
-
Quality Products:
Domains & Families for DGAT2 Gene
Gene Families for DGAT2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for DGAT2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96PD7- Family:
-
- Belongs to the diacylglycerol acyltransferase family.
Function for DGAT2 Gene
Molecular function for DGAT2 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Acyl-CoA + retinol = CoA + retinyl ester.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Inhibited by niacin.
- UniProtKB/Swiss-Prot Function:
- Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).
Enzyme Numbers (IUBMB) for DGAT2 Gene
Phenotypes From GWAS Catalog for DGAT2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003846 | 2-acylglycerol O-acyltransferase activity | IEA | -- |
| GO:0004144 | diacylglycerol O-acyltransferase activity | TAS | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016746 | transferase activity, transferring acyl groups | IEA | -- |
| GO:0016747 | transferase activity, transferring acyl groups other than amino-acyl groups | IEA | -- |
Phenotypes for DGAT2 Gene
- MGI mutant phenotypes for DGAT2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for DGAT2:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for DGAT2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DGAT2 gene
- Search ViGene Biosciences for DGAT2
CRISPR Products
-
OriGene CRISPR knockouts for DGAT2
- genomics-online: gRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- Applied Biological Materials CRISPR for DGAT2
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Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DGAT2
- GenScript: Design CRISPR guide RNA sequences for DGAT2
miRNA for DGAT2 Gene
- miRTarBase miRNAs that target DGAT2
-
- hsa-mir-218-5p (MIRT440825)
- hsa-mir-203a-3p (MIRT497955)
- hsa-mir-320e (MIRT497956)
- hsa-mir-4511 (MIRT497957)
- hsa-mir-3133 (MIRT497958)
- hsa-mir-4316 (MIRT567773)
- hsa-mir-3188 (MIRT567774)
- hsa-mir-6884-5p (MIRT567775)
- hsa-mir-485-5p (MIRT567776)
- hsa-mir-2467-5p (MIRT567777)
- hsa-mir-3975 (MIRT567778)
- hsa-mir-605-3p (MIRT567779)
- hsa-mir-3664-3p (MIRT567780)
- hsa-mir-873-5p (MIRT567781)
- hsa-mir-5582-5p (MIRT567782)
- hsa-mir-6876-5p (MIRT567783)
- hsa-mir-4476 (MIRT567784)
- hsa-mir-548ah-5p (MIRT567785)
- hsa-mir-3609 (MIRT567786)
- hsa-mir-548t-5p (MIRT567787)
- hsa-mir-548az-5p (MIRT567788)
- hsa-mir-124-3p (MIRT567789)
miRNA Products
- Search ViGene Biosciences for DGAT2
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DGAT2
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- genomics-online: shRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DGAT2 gene
Clone Products
- Sino Biological Human cDNA Clone for DGAT2
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- VectorBuilder custom plasmid, inducible vectors for DGAT2
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for DGAT2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for DGAT2
-
ViGene Biosciences adenoviral particle packaged cDNA for DGAT2 gene
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ViGene Biosciences lentiviral particle packaged cDNA for DGAT2 gene
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ViGene Biosciences ready-to-package AAV shRNAs for DGAT2 gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DGAT2 Gene
Localization for DGAT2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DGAT2 Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| mitochondrion | 4 |
| extracellular | 2 |
| peroxisome | 2 |
| cytosol | 2 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | colocalizes_with mitochondrion | ISS | -- |
| GO:0005783 | endoplasmic reticulum | IDA | 14521909 |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0005811 | colocalizes_with lipid droplet | ISS | -- |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for DGAT2 Gene
Pathways & Interactions for DGAT2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Glycerophospholipid biosynthesis | ||
| 3 | triacylglycerol biosynthesis | ||
| 4 | Fat digestion and absorption | ||
| 5 | Glycerolipid metabolism | ||
Pathways by source for DGAT2 Gene
2 BioSystems pathways for DGAT2 Gene
3 KEGG pathways for DGAT2 Gene
UniProtKB/Swiss-Prot Q96PD7-DGAT2_HUMAN
- Pathway: Glycerolipid metabolism; triacylglycerol biosynthesis.
Interacting Proteins for DGAT2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006071 | glycerol metabolic process | IEA | -- |
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0010867 | positive regulation of triglyceride biosynthetic process | IEA | -- |
| GO:0019432 | triglyceride biosynthetic process | TAS | -- |
| GO:0019915 | lipid storage | ISS | -- |
No data available for SIGNOR curated interactions for DGAT2 Gene
Drugs & Compounds for DGAT2 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (2E)-Decenoyl-CoA |
|
10018-95-8 |
|
|||
| (2E)-Dodecenoyl-CoA |
|
1066-12-2 |
|
|||
| (2E)-Hexadecenoyl-CoA |
|
4460-95-1 |
|
|||
| (2E)-Octenoyl-CoA |
|
10018-94-7 |
|
|||
| (2E)-Tetradecenoyl-CoA |
|
38795-33-4 |
|
Transcripts for DGAT2 Gene
mRNA/cDNA for DGAT2 Gene
- (3) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (183) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DGAT2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DGAT2
- genomics-online: gRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- Applied Biological Materials CRISPR for DGAT2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for DGAT2
- GenScript: Design CRISPR guide RNA sequences for DGAT2
miRNA Products
- Search ViGene Biosciences for DGAT2
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DGAT2
- Browse OriGene Inhibitory RNA Products For DGAT2
- genomics-online: shRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for DGAT2 gene
Clone Products
- Sino Biological Human cDNA Clone for DGAT2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DGAT2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DGAT2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for DGAT2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | |||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||
| SP6: |
Expression for DGAT2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Gut Tube (Gastrointestinal Tract)
- Liver (Hepatobiliary System)
- Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for DGAT2 Gene
This gene is overexpressed in Whole Blood (x12.3), Adipose - Visceral (Omentum) (x8.6), Liver (x5.2), Adipose - Subcutaneous (x4.9), Breast - Mammary Tissue (x4.4), and Skin - Sun Exposed (Lower leg) (x4.3).
This gene is overexpressed in Salivary gland (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for DGAT2 Gene
NURSA nuclear receptor signaling pathways regulating expression of DGAT2 Gene:
DGAT2SOURCE GeneReport for Unigene cluster for DGAT2 Gene:
Hs.129798mRNA Expression by UniProt/SwissProt for DGAT2 Gene:
Q96PD7-DGAT2_HUMAN
Tissue specificity:
Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin.
Evidence on tissue expression from TISSUES for DGAT2 Gene
- Lymph node(4.1)
- Pancreas(4.1)
- Liver(3.4)
- Skin(2.8)
- Blood(2.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for DGAT2
-
OriGene qPCR primer pairs for DGAT2
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for DGAT2 Gene
Orthologs for DGAT2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DGAT2 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | DGAT2 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | DGAT2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | DGAT2 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dgat2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Dgat2 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | DGAT2 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | DGAT2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dgat2 33 |
|
||
| MGC76066 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC68683 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dgat2 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG1941 35 |
|
|
|
| CG1942 35 |
|
|
|||
| CG1946 35 |
|
|
|||
| worm (Caenorhabditis elegans) |
Secernentea | Y53G8B.2 35 |
|
|
|
| W01A11.2 35 |
|
|
|||
| F59A1.10 35 |
|
|
- Species where no ortholog for DGAT2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DGAT2 Gene
(6) SIMAP similar genes for DGAT2 Gene using alignment to 5 proteins:
Variants for DGAT2 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs869025595 | uncertain-significance, not provided | 75,797,190(+) | T/C | coding_sequence_variant, missense_variant | |
| rs1000106737 | -- | 75,793,780(+) | G/A | intron_variant | |
| rs1000139436 | -- | 75,794,070(+) | A/C | intron_variant | |
| rs1000272609 | -- | 75,799,939(+) | C/T | intron_variant | |
| rs1000407142 | -- | 75,800,297(+) | G/A | intron_variant |
Residual Variation Intolerance Score:
78.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.85;
58.78% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DGAT2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DGAT2 Gene
Disorders for DGAT2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| autosomal dominant charcot-marie-tooth disease type 2 due to dgat2 mutation |
|
|
| pellagra |
|
|
Search DGAT2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DGAT2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for DGAT2 Gene
Publications for DGAT2 Gene
- Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. (PMID: 11481335) Cases S … Farese RV (The Journal of biological chemistry 2001) 2 3 4 22 58
- Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13. (PMID: 17477860) Friedel S … Hebebrand J (BMC genetics 2007) 3 22 44 58
- A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice. (PMID: 14521909) Wakimoto K … Imai Y (Biochemical and biophysical research communications 2003) 3 4 22 58
- DGAT2 Mutation in a Family with Autosomal-Dominant Early-Onset Axonal Charcot-Marie-Tooth Disease. (PMID: 26786738) Hong YB … Chung KW (Human mutation 2016) 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
Products for DGAT2 Gene
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- Find your target
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- Cloud-Clone Corp. Antibodies for DGAT2
- Cloud-Clone Corp. Proteins for DGAT2
- Cloud-Clone Corp. Assay Kits for DGAT2
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for DGAT2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for DGAT2
- VectorBuilder custom plasmid, inducible vectors for DGAT2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DGAT2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 82 available DGAT2 Antibodies ranked by validation data
- Compare Top DGAT2 Antibodies
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- antibodies-online: Search results for 5 available DGAT2 Elisa Kits ranked by validation data
- Compare Top DGAT2 Elisa Kits
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- antibodies-online: Search results for 6 available DGAT2 Proteins ranked by validation data
- Compare Top DGAT2 Proteins
- Quality Products:
- Search GeneTex for Antibodies for DGAT2
- Search GeneTex for Proteins for DGAT2
- ViGene Biosciences adenoviral particle packaged cDNA for DGAT2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for DGAT2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for DGAT2 gene
- Search ViGene Biosciences for DGAT2
- Santa Cruz Biotechnology (SCBT) Antibodies for DGAT2
- Search Santa Cruz Biotechnology (SCBT) for DGAT2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for DGAT2
- Horizon Cell Lines for DGAT2
- genomics-online: cdna clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- orf clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- genomics-online: gRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- genomics-online: primer clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
- genomics-online: shRNA clones - Search results for 124 available DGAT2 gene related products
- Overview of 124 available DGAT2 gene related products
Sources for DGAT2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew