DERL3 Gene
protein-coding GIFtS: 51
GCID: GC22M024176
|
|
derlin 3(Previous names: chromosome 22 open reading frame 14, Der1-like domain family,...)
(Previous symbol: C22orf14)
| |
Aliases
for DERL3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Derlin 31 2 | | DERtrin-32 3 | | C22orf141 2 3 | | LLN22 3 | | IZP61 2 | | FLJ438421 | | Der1-Like Domain Family, Member 31 2 | | MGC718031 | | Derlin-31 | | Chromosome 22 Open Reading Frame 141 | | Degradation In Endoplasmic Reticulum Protein 32 3 | | DERtrin 32 | | Der1-Like Protein 32 3 | | DER33 |
Export aliases for DERL3 gene to outside databasesPrevious GC identifers: GC22M022504 GC22M007164 |
Summaries
for DERL3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DERL3:
The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteinsthat are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. Thisprotein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively splicedtranscript variants encoding different isoforms have been identified for this gene. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: DERL3_HUMAN, Q96Q80Function: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenalglycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows theretrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by theproteasome. May mediate the interaction between VCP and the degradation substrate
Gene Wiki entry for DERL3 (Derlin-3)
|
Genomic Views
for DERL3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DERL3 gene promoter:
NF-1 RFX1 Elk-1 p300 HTF GATA-1 FOXL1 FAC1 FOXO1 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for DERL3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DERL3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23DERL3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M024176: view genomic region
(about GC identifiers)
Start:
|
24,176,690 bp from pter |
End:
|
24,181,315 bp from pter |
Size:
|
4,626 bases |
Orientation:
|
minus strand |
|
Proteins
for DERL3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DERL3_HUMAN, Q96Q80 (See
protein sequence)Recommended Name: Derlin-3 Size: 235 amino acids; 26679 Da
Subunit: Forms homo- and heterooligomers with DERL2 and, to a lesser extent, with DERL1. Interacts with VCP and EDEM1
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: F2Z3B6 Q6ICJ6 Q6PEX0 Q6ZUB5Alternative splicing: 5 isoforms: Q96Q80-1 Q96Q80-2 Q96Q80-3 Q96Q80-4 Q96Q80-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DERL3: NX_Q96Q80
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96Q80
DERL3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001002862.1 NP_001129223.1 NP_940842.2
ENSEMBL proteins: ENSP00000384744 ENSP00000384473 ENSP00000315303 ENSP00000419399
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030176 | integral to endoplasmic reticulum membrane |
IDA | 16449189 |
DERL3 for ontologies About GeneDecksing
DERL3 Antibody Products:
Assay Products for DERL3: |
Protein
Domains /
Families
for DERL3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DERL3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96Q80ProtoNet protein and cluster: Q96Q80 UniProtKB/Swiss-Prot: DERL3_HUMAN, Q96Q80Similarity: Belongs to the derlin family |
Function
for DERL3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DERL3_HUMAN, Q96Q80Function: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenalglycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows theretrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by theproteasome. May mediate the interaction between VCP and the degradation substrateInduction: Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded proteinresponse (UPR) (By similarity)
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for DERL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
DERL3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for DERL3:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Derl3):
DERL3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DERL3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for DERL3):
DERL3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DERL3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/9 Interacting proteins for DERL3 (Q96Q803 ENSP000003847444) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0018279 | protein N-linked glycosylation via asparagine |
IMP | -- | | GO:0030433 | ER-associated protein catabolic process |
NAS | 16449189 | | GO:0030968 | endoplasmic reticulum unfolded protein response |
IDA | 16449189 |
DERL3 for ontologies About GeneDecksing
|
Drugs & Compounds
for DERL3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DERL3
Search CenterWatch for drugs/clinical trials and news about DERL3
|
Transcripts
for DERL3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DERL3 gene (3 alternative transcripts): NM_001002862.2 NM_001135751.1 NM_198440.3 Unigene Cluster for DERL3: Derlin 3 Hs.593679 [show with all ESTs]Unigene Representative Sequence: AK12583010 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000464023 ENST00000406855(uc002zyk.4) ENST00000404056 ENST00000290730(uc002zyh.3 uc002zyi.3 uc002zyj.3)
ENST00000493596 ENST00000464034 ENST00000488272 ENST00000318109 ENST00000476077
ENST00000464110
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DERL3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): DERL3 (NM_001002862) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DERL3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL3 |
Additional cDNA sequence: AK092582.1 AK096976.1 AK125830.1 AL389876.1 AL389879.1 BC057830.1 CR456372.1 9 DOTS entries: DT.75148775 DT.101983658 DT.310401 DT.455813 DT.75100295 DT.95364661 DT.100023252 DT.120671507 DT.92424325 24/90 AceView cDNA sequences (see all 90): BM723688 AI867737 AI681837 BM713985 BE218231 BM792257 BE503794 BG149188 AA830970 AI968197 AI148507 BM769484 NM_001002862 BM713999 AI216564 NM_198440 BF433930 BE467075 BE466009 AW296853 BM129595 AW135031 AA243616 AI831078
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for DERL3 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 |
|---|
|
| SP1: | | | - | | | | | | | | - | | | | | | | | - | | | | - | | - | | | | |
| SP2: | | | - | | | | | | | | - | | | | | | | | - | | | | - | | | | | | |
| SP3: | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for DERL3
|
Expression
for DERL3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DERL3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAGGGCCCA
About this image
See DERL3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DERL3
SOURCE GeneReport for Unigene cluster: Hs.593679
UniProtKB/Swiss-Prot: DERL3_HUMAN, Q96Q80Tissue specificity: Unlike DERL1 and DERL2, restricted to several tissues. Expressed at high levels in placenta,pancreas, spleen and small intestine
SABiosciences Custom PCR Arrays for DERL3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DERL3
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL3 |
Orthologs
for DERL3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DERL3 gene from 6/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
DERL36 |
Der1-like domain family, member 3 |
71(a) |
1 ↔ 1 |
15(8257577-8262050) |
zebrafish
(Danio rerio) |
Actinopterygii |
derl31 |
Der1-like domain family, member 3 |
73.36(n)
78.54(a) |
|
393877 NM_200903.1 NP_957197.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Der-26 |
Derlin-2 |
51(a) |
1 → many |
3R(12308416-12310125) |
worm
(Caenorhabditis elegans) |
Secernentea |
R151.66 |
Derlin-2 |
55(a) |
1 → many |
III(7221678-7223069) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
DER2.26DER2.16 |
derlin-2.1 |
41(a)41(a) |
many ↔ manymany ↔ many |
4(2459880-2461739) 4(11575096-11577195) |
rice
(Oryza sativa) |
Liliopsida |
-- |
Der1-like family domain containing protein, expres... |
42(a) |
1 → many |
3(35876387-35881087) |
ENSEMBL Gene Tree for DERL3 (if available)
TreeFam Gene Tree for DERL3 (if available) |
Paralogs
for DERL3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DERL3 gene
- DERL12 DERL22
2 SIMAP similar genes for DERL3 using alignment to 2 protein entries: DERL3_HUMAN (see all proteins):DERL2 DERL1
DERL3 for paralogs About GeneDecksing
|
Genomic Variants
for DERL3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DERL3 (24176690 - 24181315 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DERL3: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DERL3 |
|
Disorders
/ Diseases
for DERL3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DERL3 for disorders About GeneDecksing
OMIM gene information: 610305
OMIM disorders: --
1  disease for DERL3: About MalaCardsmalaria
Export disorders for DERL3 gene to outside databases
|
Publications
for DERL3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DERL3 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with DERL3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. (PubMed id 16449189)1, 2 Oda Y.... Mori K. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A membrane protein required for dislocation of misfolded proteins from the ER. (PubMed id 15215855)1, 3 Lilley B.N. and Ploegh H.L. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein. (PubMed id 22607976)2 Sato T.... Kai H. (2012)
- The transmembrane segment of a tail-anchored protein d etermines its degradative fate through dislocation from the endoplasmic reticulu m. (PubMed id 20435896)1 Claessen J.H....Ploegh H.L. (2010)
- USP14 inhibits ER-associated degradation via interaction with IRE1alpha. (PubMed id 19135427)1 Nagai A.... Ichijo H. (2009)
- Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508. (PubMed id 18216283)1 Morito D....Nagata K. (2008)
|
External Searches for DERL3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DERL3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DERL3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DERL3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DERL3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DERL3 gene:
Search GeneIP for patents involving DERL3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DERL3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DERL3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DERL3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DERL3 | | | OriGene Protein Over-expression Lysate for DERL3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DERL3 | | OriGene 3'-UTR Clone for DERL3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DERL3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DERL3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DERL3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DERL3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DERL3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DERL3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DERL3 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for DERL3 |
| |  |  |  |  | | | | |
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 | | | DERL3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL3 |
|  |  |  | | | | ThermoFisher Antibody for DERL3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL3 |
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