DERL2 Gene
protein-coding GIFtS: 53
GCID: GC17M005374
|
|
derlin 2(Previous names: Der1-like domain family, member 2 )
| |
Aliases for DERL2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Derlin 21 2 | | Der1-Like Protein 22 3 | | F-LAN-11 2 3 | | DERtrin-22 3 | | F-LANa1 2 3 | | CGI-1011 | | FLANa1 2 | | Carcinoma Related2 | | Der1-Like Domain Family, Member 21 2 | | DER23 | | Derlin-21 | | FLANA3 | | Degradation In Endoplasmic Reticulum Protein 22 3 | | |
Export aliases for DERL2 gene to outside databasesPrevious GC identifers: GC17M005311 GC17M005269 |
Summaries for DERL2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for DERL2: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain thehomeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006(PubMed 16449189)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: DERL2_HUMAN, Q9GZP9Function: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenalglycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows theretrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by theproteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is notinvolved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role incell proliferation Gene Wiki entry for DERL2 (Derlin-2)
|
Genomic Views for DERL2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DERL2 gene promoter: POU3F1 HNF-3beta E47 CREB deltaCREB Hand1 ZID MRF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for DERL2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DERL2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.2 Ensembl cytogenetic band: 17p13.2 HGNC cytogenetic band: 17p13.2DERL2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M005374: view genomic region
(about GC identifiers)
Start:
|
5,374,571 bp from pter |
End:
|
5,390,131 bp from pter |
Size:
|
15,561 bases |
Orientation:
|
minus strand |
|
Proteins for DERL2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DERL2_HUMAN, Q9GZP9 (See
protein sequence)Recommended Name: Derlin-2 Size: 239 amino acids; 27567 Da
Subunit: Forms homo- and heterooligomers with DERL3 and, to a lesser extent, with DERL1. Interacts with VIMP, VCP andEDEM1. Mediates association between VCP and EDEM1, as well as that between VCP and the degradation substrate.Interacts with the SEL1L/SYVN1 and VCP/VIMP protein complexes. Interacts with OS9
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAD34096.1; Type=Frameshift; Positions=122, 128, 136;
Secondary accessions: Q9Y3A7Explore the universe of human proteins at neXtProt for DERL2: NX_Q9GZP9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9GZP9 DERL2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057125.2 ENSEMBL proteins: ENSP00000158771 ENSP00000460671 ENSP00000459083 ENSP00000459072 ENSP00000461603 ENSP00000467794 ENSP00000458296 ENSP00000459154 ENSP00000458448 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DERL2 for ontologies About GeneDecksing
DERL2 Antibody Products: Assay Products for DERL2: |
Protein
Domains / Families for DERL2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DERL2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9GZP9ProtoNet protein and cluster: Q9GZP9 UniProtKB/Swiss-Prot: DERL2_HUMAN, Q9GZP9Similarity: Belongs to the derlin family |
Function for DERL2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: DERL2_HUMAN, Q9GZP9Function: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenalglycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows theretrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by theproteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is notinvolved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role incell proliferationInduction: Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded proteinresponse (UPR) (By similarity)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DERL2 (NM_016041) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DERL2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
DERL2 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for DERL2: Animal Models: Mouse knock-out Derl2tm1.2Hpl for DERL2 10 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Derl2):
DERL2 for phenotypes About GeneDecksing
|
Pathways & Interactions for DERL2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Kegg Pathway (Kegg details for DERL2):
DERL2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DERL2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
 5/16 Interacting proteins for DERL2 (Q9GZP92, 3 ENSP000001587714) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
DERL2 for ontologies About GeneDecksing
|
Drugs & Compounds for DERL2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for DERL2 Search CenterWatch for drugs/clinical trials and news about DERL2 
|
Transcripts for DERL2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DERL2 gene: NM_016041.3 Unigene Cluster for DERL2: Derlin 2 Hs.286131 [show with all ESTs]Unigene Representative Sequence: BM47849313 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000158771(uc002gcc.1) ENST00000573547 ENST00000572834 ENST00000575605 ENST00000570848 ENST00000571476 ENST00000576551 ENST00000571971 ENST00000574952 ENST00000573637 ENST00000574700 ENST00000575209 ENST00000571968
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DERL2 (NM_016041) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DERL2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL2  |
Additional cDNA sequence: AF132289.1 AF151859.1 AF208065.1 AF242523.1 AK024574.1 BC009549.1 BC010890.1 CR457202.1 15 DOTS entries: DT.416707 DT.97858628 DT.120915551 DT.120915554 DT.91780523 DT.95175796 DT.97789599 DT.91947548 DT.95289965 DT.100667496 DT.102824189 DT.91733738 DT.91780552 DT.92325715 DT.95221098 24/190 AceView cDNA sequences (see all 190): AI079408 BF724670 BM977259 BE669452 BE504275 AI311856 BU431516 CA309968 CA487513 CR457202 AA383378 AA910984 BM725584 BX494802 AW268612 BM985357 CA495258 AI240536 BE551456 AI089034 AA419545 CA308385 AV725011 AI695003 GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for DERL2 (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DERL2
|
Expression for DERL2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DERL2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GTGTAAATGG
About this image See DERL2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DERL2
SOURCE GeneReport for Unigene cluster: Hs.286131 UniProtKB/Swiss-Prot: DERL2_HUMAN, Q9GZP9Tissue specificity: Ubiquitous. Overexpressed in various hepatocarcinomas SABiosciences Expression via Pathway-Focused PCR Array including DERL2:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DERL2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DERL2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DERL2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DERL2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL2 |
Orthologs for DERL2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DERL2 gene from 8/32 species (see all 32) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
DERL21 |
Der1-like domain family, member 2 |
84.1(n) 93.31(a) |
  |
417498 XM_415746.3 XP_415746.2 |
lizard (Anolis carolinensis) |
Reptilia |
DERL26 |
-- |
92(a) |
1 ↔ 1 |
GL343393.1(344984-350515) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.168152 |
Xenopus laevis transcribed sequence with weak similarity more |
78.03(n) |
  |
48050457 |
zebrafish (Danio rerio) |
Actinopterygii |
zgc639912 |
hypothetical protein MGC63991 |
73.62(n) |
  |
393877 BC064666.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Der-21 |
Derlin-2 |
64.8(n) 65.09(a) |
  |
42005 NM_142296.2 NP_650553.1 |
worm (Caenorhabditis elegans) |
Secernentea |
R151.61 |
Protein R151.6 |
63.64(n) 69.09(a) |
  |
176018 NM_066189.4 NP_498590.4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
DER2.11 |
derlin-2.1 |
55.93(n) 51.71(a) |
  |
828269 NM_118301.6 NP_193912.3 |
rice (Oryza sativa) |
Liliopsida |
Os03g08522001 |
hypothetical protein |
56.83(n) 52.42(a) |
  |
4334809 NM_001058456.1 NP_001051921.1 |
ENSEMBL Gene Tree for DERL2 (if available) TreeFam Gene Tree for DERL2 (if available)  |
Paralogs for DERL2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for DERL2 gene
- DERL12 DERL32
2 SIMAP similar genes for DERL2 using alignment to 8 protein entries: DERL2_HUMAN (see all proteins):DERL3 DERL1
DERL2 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for DERL2 PGOHUM00000262493 PGOHUM00000233586
|
Genomic Variants for DERL2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DERL2 (5374571 - 5390131 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for DERL2: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DERL2 |
|
Disorders
/ Diseases for DERL2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DERL2 for disorders About GeneDecksing
OMIM gene information: 610304
OMIM disorders: --
5 diseases for DERL2: About MalaCardscarcinoma cholera liver cancer malaria neuronitis Export disorders for DERL2 gene to outside databases
|
Publications for DERL2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DERL2 gene, integrated from 9 sources (see all 23): (articles sorted by number of sources associating them with DERL2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and characterization of F-LANa, upregulated in human liver cancer. (PubMed id 11500051)1, 2, 3 Ying H.... Xu Y. (2001)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
- Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. (PubMed id 16186509)1, 2, 9 Lilley B.N. and Ploegh H.L. (2005)
- Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. (PubMed id 16449189)1, 2 Oda Y.... Mori K. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A membrane protein required for dislocation of misfolded proteins from the ER. (PubMed id 15215855)1, 2 Lilley B.N. and Ploegh H.L. (2004)
- EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites. (PubMed id 17360537)1, 9 Zuber C....Roth J. (2007)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- BAT3 guides misfolded glycoproteins out of the endopla smic reticulum. (PubMed id 22174835)1 Claessen J.H. and Ploegh H.L. (2011)
- Importin beta interacts with the endoplasmic reticulu m-associated degradation machinery and promotes ubiquitination and degradation of mutant alpha1-antitrypsin. (PubMed id 21832065)1 Zhong Y....Fang S. (2011)
|
External Searches for DERL2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DERL2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DERL2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DERL2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for DERL2 gene: Search GeneIP for patents involving DERL2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for DERL2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for DERL2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DERL2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DERL2 | | OriGene Protein Over-expression Lysate for DERL2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for DERL2 | | OriGene 3'-UTR Clone for DERL2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DERL2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for DERL2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for DERL2 | | OriGene Custom Protein Services for DERL2 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DERL2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DERL2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DERL2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DERL2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DERL2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DERL2 |
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| | | Search Tocris compounds for DERL2 |
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 | | DERL2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERL2 |
|  |  |  | | | Search ThermoFisher Antibodies for DERL2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERL2 |
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