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DERA Gene

protein-coding   GIFtS: 55
GCID: GC12P016064

Deoxyribose-Phosphate Aldolase (Putative)

(Previous name: 2-deoxyribose-5-phosphate aldolase homolog (C. elegans))
  See DERA-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Deoxyribose-Phosphate Aldolase (Putative)1 2     deoxyriboaldolase2
2-Deoxy-D-Ribose 5-Phosphate Aldolase2 3     phosphodeoxyriboaldolase2
EC 4.1.2.43 8     Putative Deoxyribose-Phosphate Aldolase2
2-Deoxyribose-5-Phosphate Aldolase Homolog (C. Elegans)1     Deoxyriboaldolase3
2-Deoxyribose-5-Phosphate Aldolase Homolog2     Phosphodeoxyriboaldolase3
DEOC2     

External Ids:    HGNC: 242691   Entrez Gene: 510712   Ensembl: ENSG000000236977   UniProtKB: Q9Y3153   

Export aliases for DERA gene to outside databases

Previous GC identifers: GC12P015956 GC12P015833


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DERA Gene:
DERA (deoxyribose-phosphate aldolase (putative)) is a protein-coding gene. Diseases associated with DERA include phlebotomus fever, and tick infestation. GO annotations related to this gene include deoxyribose-phosphate aldolase activity.

UniProtKB/Swiss-Prot: DEOC_HUMAN, Q9Y315
Function: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate
2-deoxy-D-ribose 5-phosphate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_009714.18  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DERA gene promoter:
         CREB   ER-alpha   TBP   PPAR-gamma1   AML1a   FOXJ2 (long isoform)   PPAR-gamma2   POU3F2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDERA promoter sequence
   Search Chromatin IP Primers for DERA

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DERA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12.3   Ensembl cytogenetic band:  12p12.3   HGNC cytogenetic band: 12p12.3

DERA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DERA gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P016064:  view genomic region     (about GC identifiers)

Start:
16,064,106 bp from pter      End:
16,190,315 bp from pter
Size:
126,210 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DEOC_HUMAN, Q9Y315 (See protein sequence)
Recommended Name: Putative deoxyribose-phosphate aldolase  
Size: 318 amino acids; 35231 Da
Sequence caution: Sequence=AAD27735.1; Type=Erroneous initiation; Sequence=AAH56234.1; Type=Erroneous initiation;
Sequence=BAD96261.1; Type=Erroneous initiation;
Secondary accessions: Q53HN9 Q6PHW2

Explore the universe of human proteins at neXtProt for DERA: NX_Q9Y315

Explore proteomics data for DERA at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for DERA (Q9Y315)
     FIKTSTG  AHLKTILATGEL 


    See DERA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057038.2  
    ENSEMBL proteins: 
     ENSP00000416583   ENSP00000435683   ENSP00000432633   ENSP00000433051   ENSP00000433801  
     ENSP00000436999   ENSP00000434973   ENSP00000431757  

    DERA Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for DERA
    OriGene Custom MassSpec
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    GenScript Custom Purified and Recombinant Proteins Services for DERA
    Novus Biologicals DERA Proteins
    Novus Biologicals DERA Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for DERA
    Cloud-Clone Corp. Proteins for DERA

     
    Search eBioscience for Proteins for DERA 

     
    antibodies-online proteins for DERA (4 products) 

     
    antibodies-online peptides for DERA

    DERA Antibody Products:

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    Search ThermoFisher Antibodies for DERA
    antibodies-online antibodies for DERA (10 products) 

    DERA Assay Products:

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    Cloud-Clone Corp. ELISAs for DERA
    Cloud-Clone Corp. CLIAs for DERA
    Search eBioscience for ELISAs for DERA 
    antibodies-online kits for DERA (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR013785 Aldolase_TIM
     IPR002915 DeoC/FbaB/lacD_aldolase
     IPR011343 DeoC

    Graphical View of Domain Structure for InterPro Entry Q9Y315

    ProtoNet protein and cluster: Q9Y315

    1 Blocks protein domain: IPB002915 Deoxyribose-phosphate aldolase

    UniProtKB/Swiss-Prot: DEOC_HUMAN, Q9Y315
    Similarity: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily


    Find genes that share domains with DERA           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DEOC_HUMAN, Q9Y315
    Function: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate
    2-deoxy-D-ribose 5-phosphate (By similarity)
    Catalytic activity: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde

         Enzyme Number (IUBMB): EC 4.1.2.41 2

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004139deoxyribose-phosphate aldolase activity IDA9226884
    GO:0016829lyase activity ----
         
    Find genes that share ontologies with DERA           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DERA:
     Decreased cell number 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DERA

    miRNA
    Products:
        
    miRTarBase miRNAs that target DERA:
    hsa-mir-26b-5p (MIRT029949), hsa-mir-222-3p (MIRT046612)

    Block miRNA regulation of human, mouse, rat DERA using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate DERA
    SwitchGear 3'UTR luciferase reporter plasmidDERA 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DERA

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: DERA (NM_015954)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DERA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERA

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DERA 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERA


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    plasma membrane2
    cytoskeleton1
    endoplasmic reticulum1
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with DERA           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DERA About    
    See pathways by source

    SuperPathContained pathways About
    1Pentose phosphate pathway (KEGG)
    Pentose phosphate pathway


    Find genes that share SuperPaths with DERA           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for DERA):
        Pentose phosphate pathway

    UniProtKB/Swiss-Prot: DEOC_HUMAN, Q9Y315
    Pathway: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and
    acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DERA
    Interactions:

        Search GeneGlobe Interaction Network for DERA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DERA (Q9Y3151, 3 ENSP000004165834) via UniProtKB, MINT, STRING, and/or I2D (see all 61)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PAAF1Q9BRP41, 3, ENSP000003116654EBI-1048152,EBI-1056358 I2D: score=2 STRING: ENSP00000311665
    DDA1Q9BW613I2D: score=1 
    RBKSENSP000003068174STRING: ENSP00000306817
    TALDO1ENSP000003212594STRING: ENSP00000321259
    TKTENSP000004054554STRING: ENSP00000405455
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009264deoxyribonucleotide catabolic process IEA--
    GO:0046121deoxyribonucleoside catabolic process IDA9226884
    GO:0046386deoxyribose phosphate catabolic process IEA--

    Find genes that share ontologies with DERA           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DERA (DEOC)

    3 HMDB Compounds for DERA    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetaldehydeacetaldehyde (see all 5)75-07-0--
    D-Glyceraldehyde 3-phosphate2-hydroxy-3-(phosphonooxy)-Propanal (see all 11)142-10-9--
    Deoxyribose 5-phosphate2-deoxy-alpha-D-ribose 5-phosphate (see all 12)102916-66-5--

    3 Novoseek inferred chemical compound relationships for DERA gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    deoxyribose-5-phosphate 97.3 2 15069189 (1), 9226884 (1)
    deoxyribose 76.1 2 12467706 (1), 9226884 (1)
    aldol 75 3 12467706 (1), 15069189 (1)



    Find genes that share compounds with DERA           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DERA gene: 
    NM_015954.2  

    Unigene Cluster for DERA:

    Deoxyribose-phosphate aldolase (putative)
    Hs.39429  [show with all ESTs]
    Unigene Representative Sequence: NM_015954
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000428559(uc001rde.3) ENST00000526521 ENST00000524480 ENST00000531803
    ENST00000528821(uc010shx.1) ENST00000532964 ENST00000533447 ENST00000526530
    ENST00000530274 ENST00000532573
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidDERA 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DERA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DERA
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for DERA
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DERA
      QuantiTect SYBR Green Assays in human, mouse, rat DERA
      Search QuantiFast Probe-based Assays in human, mouse, rat DERA

    Additional mRNA sequence: 

    AF132960.1 AK024614.1 AK222541.1 AK296697.1 AK309182.1 BC041328.1 BC056234.1 

    12 DOTS entries:

    DT.100801103  DT.446471  DT.95338904  DT.95338919  DT.100801106  DT.121177442  DT.95338905  DT.99983803 
    DT.100026557  DT.100801112  DT.92041577  DT.95153999 

    Selected AceView cDNA sequences (see all 278):

    AA482173 AA714063 BG499218 BE349138 AI280241 H69194 CR607223 AI364071 
    AI085092 BI908208 CR597600 BI850268 BU627881 CA429275 AA461420 BQ432433 
    AI339716 CR594810 BU618784 CA389498 AI167768 AI611772 AV650563 CB851336 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DERA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGTACTCAT
    DERA Expression
    About this image

    DERA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DERA Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.39429
        Custom PCR Arrays for DERA
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DERA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DERA gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dera1 , 5 2-deoxyribose-5-phosphate aldolase homolog (C. elegans)1, 5 85.53(n)1
    92.45(a)1
      6 (67.32 cM)5
    2324491  NM_172733.11  NP_766321.11 
     1377545775 
    chicken
    (Gallus gallus)
    Aves DERA1 deoxyribose-phosphate aldolase (putative) 73.48(n)
    76.73(a)
      418176  NM_001006248.1  NP_001006248.1 
    lizard
    (Anolis carolinensis)
    Reptilia DERA6
    deoxyribose-phosphate aldolase (putative)
    83(a)
    1 ↔ 1
    GL343336.1(807013-840675)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162542 Xenopus laevis transcribed sequence with moderate similarity more 74.55(n)    BU904422.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc566772 similar to serine/threonine kinase receptor associated more 76.81(n)   393274  BC049525.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG85251 CG8525 56.24(n)
    55.4(a)
      36358  NM_136937.3  NP_610781.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F09E5.31 F09E5.3 58.44(n)
    55.65(a)
      173911  NM_062608.5  NP_495009.1 
    rice
    (Oryza sativa)
    Liliopsida Os.158102 Oryza sativa (japonica cultivar-group) cDNA clone0 more 75.45(n)    AK100386.1 


    ENSEMBL Gene Tree for DERA (if available)
    TreeFam Gene Tree for DERA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DERA (see all 2423)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs359564331,2
    C--15947699(+) GAGGCT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1807046041,2
    --16062328(+) TTAGGA/TTATCA 1 -- us2k10--------
    rs1113036631,2
    C,F--16062330(+) AGGATG/ATCACA 1 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs1465427191,2
    C--16062336(+) TCACAA/GTTTAA 1 -- us2k10--------
    rs1491458681,2
    --16062445(+) TTCTAC/GAGATG 1 -- us2k10--------
    rs108462471,2
    C,F,A,H--16062450(+) GAGATG/ATGAAT 1 -- us2k119Minor allele frequency- A:0.50NS EA NA WA 2334
    rs1885784871,2
    --16062621(+) TTTGGA/GGAAAG 1 -- us2k10--------
    rs1159902151,2
    F--16062669(+) GGTGAT/CAGTAG 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1811932311,2
    --16062856(+) GCTGTC/GCTGTG 1 -- us2k10--------
    rs1869252721,2
    --16062955(+) TCAAGA/GTTAAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DERA (16064106 - 16190315 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DERA:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2647271CNV Deletion19546169
    esv2659461CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DERA
    DNA2.0 Custom Variant and Variant Library Synthesis for DERA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for DERA:    
    About MalaCards
    phlebotomus fever    tick infestation

    2 diseases from the University of Copenhagen DISEASES database for DERA:
    Phlebotomus fever     Tick infestation

    Find genes that share disorders with DERA           About GenesLikeMe

    Genetic Association Database (GAD): DERA
    Human Genome Epidemiology (HuGE) Navigator: DERA (1 document)

    Export disorders for DERA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DERA gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with DERA)
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    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Phylogenetic analyses of diplomonad genes reveal frequent lateral gene transfers affecting eukaryotes. (PubMed id 12546782)1, 3 Andersson J.O....Roger A.J. (Curr. Biol. 2003)
    3. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    4. Channelling of deoxyribose moiety of exogenous DNA into carbohydrate metabolism: role of deoxyriboaldolase. (PubMed id 9226884)1, 9 Sgarrella F....Tozzi M.G. (amp 1997)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51071 HGNC: 24269 AceView: CGI-26 Ensembl:ENSG00000023697 euGenes: HUgn51071
    ECgene: DERA Kegg: 51071 H-InvDB: DERA

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DERA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DERA gene:
    Search GeneIP for patents involving DERA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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