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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DEPDC5 Gene

protein-coding   GIFtS: 50
GCID: GC22P032149

DEP Domain Containing 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DEP Domain Containing 51 2
DEP.52
FFEVF2
DEP Domain-Containing Protein 52
KIAA06453

External Ids:    HGNC: 184231   Entrez Gene: 96812   Ensembl: ENSG000001001507   OMIM: 6141915   UniProtKB: O751403   

Export aliases for DEPDC5 gene to outside databases

Previous GC identifers: GC22P030476 GC22P030477 GC22P015105


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DEPDC5 Gene: 
DEPDC5 (DEP domain containing 5) is a protein-coding gene. Diseases associated with DEPDC5 include hepatitis c, and hepatocellular carcinoma.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  NC_018933.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DEPDC5 gene promoter:
         NF-1   NF-1/L   PPAR-gamma1   Egr-1   PPAR-gamma2   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDEPDC5 promoter sequence
   Search SABiosciences Chromatin IP Primers for DEPDC5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEPDC5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q12.3   Ensembl cytogenetic band:  22q12.2   HGNC cytogenetic band: 22q12.3

DEPDC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEPDC5 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P032149:  view genomic region     (about GC identifiers)

Start:
32,149,937 bp from pter      End:
32,303,020 bp from pter
Size:
153,084 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DEPD5_HUMAN, O75140 (See protein sequence)
Recommended Name: DEP domain-containing protein 5  
Size: 1603 amino acids; 181264 Da
Subcellular location: Cytoplasm, cytosol (By similarity). Cytoplasm, perinuclear region (By similarity)
Sequence caution: Sequence=BAA31620.2; Type=Erroneous initiation; Sequence=CAH18159.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=CAI17976.1; Type=Erroneous initiation; Sequence=CAI18778.1;
Type=Erroneous initiation; Sequence=CAI19699.1; Type=Erroneous initiation;
Secondary accessions: A6H8V6 A8MPX9 B4DH93 B9EGN9 Q5K3V5 Q5THY9 Q5THZ0 Q5THZ1 Q5THZ3 Q68DR1
Q6MZX3 Q6PEZ1 Q9UGV8 Q9UH13
Alternative splicing: 10 isoforms:  O75140-10   O75140-2   O75140-3   O75140-4   O75140-5   O75140-6   O75140-7   O75140-8   
O75140-9   O75140-1   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DEPDC5: NX_O75140

Explore proteomics data for DEPDC5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75140

  • DEPDC5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DEPDC5 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001007189.1  NP_001129501.1  NP_001229825.1  NP_001229826.1  NP_055477.1  

    ENSEMBL proteins: 
     ENSP00000416314   ENSP00000405351   ENSP00000383101   ENSP00000371546   ENSP00000371545  
     ENSP00000383107   ENSP00000412057   ENSP00000402173   ENSP00000410544   ENSP00000440210  
     ENSP00000266091   ENSP00000383108   ENSP00000383105   ENSP00000371539   ENSP00000441358  
     ENSP00000446286  

    Human Recombinant Protein Products for DEPDC5: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DEPDC5 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005765lysosomal membrane IDA17897319
    GO:0005829cytosol ISS--
    GO:0048471perinuclear region of cytoplasm ISS--

    DEPDC5 for ontologies           About GeneDecksing



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    Assay Products for DEPDC5: 
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    Cloud-Clone Corp. CLIAs for DEPDC5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR027244 IML1
     IPR011991 WHTH_DNA-bd_dom
     IPR000591 DEP_dom

    Graphical View of Domain Structure for InterPro Entry O75140

    ProtoNet protein and cluster: O75140

    1 Blocks protein domain: IPB000591 Pleckstrin putative G-protein interacting domain

    UniProtKB/Swiss-Prot: DEPD5_HUMAN, O75140
    Similarity: Belongs to the IML1 family
    Similarity: Contains 1 DEP domain


    DEPDC5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
         
    DEPDC5 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for DEPDC5:
     Decreased BPV1 E2 protein expr  Decreased number of cells in m  Decreased p24 protein expressi  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DEPDC5 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DEPDC5 
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    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidDEPDC5 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEPDC5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DEPDC5

    5/65 Interacting proteins for DEPDC5 (O751403) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=5 
    HIST1H4BP628053I2D: score=5 
    HIST1H4CP628053I2D: score=5 
    HIST1H4DP628053I2D: score=5 
    HIST1H4EP628053I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035556intracellular signal transduction IEA--

    DEPDC5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DEPDC5 (DEPD5)

    Search CenterWatch for drugs/clinical trials and news about DEPDC5 / DEPD5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DEPDC5 gene (5 alternative transcripts): 
    NM_001007188.2  NM_001136029.2  NM_001242896.1  NM_001242897.1  NM_014662.3  

    Unigene Cluster for DEPDC5:

    DEP domain containing 5
    Hs.435022  [show with all ESTs]
    Unigene Representative Sequence: NM_001242896
    18/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000437411 ENST00000469969 ENST00000456178 ENST00000400242(uc003alr.2)
    ENST00000382112(uc003alt.3 uc010gwk.3) ENST00000382111(uc011alw.1)
    ENST00000400248(uc003alw.3 uc011alx.2 uc011aly.2) ENST00000458532
    ENST00000469974 ENST00000473802 ENST00000448753 ENST00000433147 ENST00000462414
    ENST00000471914 ENST00000494065 ENST00000490731 ENST00000494060 ENST00000479261

    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate DEPDC5 (see all 9):
    hsa-miR-323-3p hsa-miR-513b hsa-miR-600 hsa-miR-2115 hsa-miR-532-3p hsa-miR-1224-3p hsa-miR-205* hsa-miR-552
    SwitchGear 3'UTR luciferase reporter plasmidDEPDC5 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB014545.1 AJ698950.1 AJ698951.1 AJ704764.1 AK294583.1 AK294987.1 AK299886.1 AK300737.1 
    AK309008.1 AK316364.1 BC057797.1 BC136612.1 BC144291.1 BC146766.1 BX640828.1 CR749304.1 

    15 DOTS entries:

    DT.109298  DT.99927935  DT.120640154  DT.120640151  DT.100716040  DT.91748683  DT.91748685  DT.95110519 
    DT.440524  DT.120640182  DT.102832391  DT.120640152  DT.75179767  DT.87015482  DT.95150106 

    24/83 AceView cDNA sequences (see all 83):

    AB014545 AL706192 AI874200 BQ879789 BX640828 CA424072 CB242102 BU675648 
    BC057797 H55269 BE740086 CD643403 AW603265 BU585000 BE241631 AW841131 
    CA310381 CD701301 BE819044 AA215487 BG028472 BP354669 CR749304 BE241604 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DEPDC5 (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23a · 23b ^ 24a ·
    SP1:                                                                                                                                      -                     
    SP2:                                                                                                                                      -                     
    SP3:                                                                                                                                      -                 -   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                        -   

    ExUns: 24b ^ 25 ^ 26a · 26b ^ 27a · 27b · 27c · 27d ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37a · 37b ^ 38 ^ 39a · 39b ^ 40 ^ 41 ^ 42 ^ 43 ^
    SP1:              -           -     -                                                                       -                                                   
    SP2:              -           -     -                                                     -                 -                                                   
    SP3:  -     -                 -     -                                                     -                 -                                                   
    SP4:                                                                                                                                                            
    SP5:  -     -     -           -                                                                             -           -                                       

    ExUns: 44a · 44b ^ 45
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for DEPDC5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DEPDC5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATGTCCTCG
    DEPDC5 Expression
    About this image


    See DEPDC5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DEPDC5

    SOURCE GeneReport for Unigene cluster: Hs.435022

    UniProtKB/Swiss-Prot: DEPD5_HUMAN, O75140
    Tissue specificity: Expressed in developing and adult brain

        SABiosciences Custom PCR Arrays for DEPDC5
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEPDC5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DEPDC5 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Depdc51 , 5 DEP domain containing 51, 5 90.05(n)1
    94.91(a)1
      5 (17.35 cM)5
    2778541  NM_001170567.11  NP_001164038.11 
     328637015 
    chicken
    (Gallus gallus)
    Aves DEPDC51 DEP domain containing 5 81.14(n)
    89(a)
      416956  XM_415249.3  XP_415249.3 
    lizard
    (Anolis carolinensis)
    Reptilia DEPDC56
    Uncharacterized protein
    84(a)
    1 ↔ 1
    GL343947.1(1-6712)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ032366.12   -- 74.72(n)    BJ032366.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.32342 Transcribed sequence with moderate similarity to protein more 78.53(n)    57052383 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120901 CG12090 49.97(n)
    42.45(a)
      38176  NM_167888.1  NP_728620.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T08A11.16
    Protein T08A11.1
    19(a)
    1 ↔ 1
    III(4248155-4263048)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes IML1(YJR138W)4 Subunit of the SEA (Seh1-associated) complex, a coatomer-related more   --   10(684567-689321) 853603  NP_012672.1 


    ENSEMBL Gene Tree for DEPDC5 (if available)
    TreeFam Gene Tree for DEPDC5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3281 SNPs in DEPDC5 are shown (see all 3281)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0692644
    ----see VAR_0692642 R Q mis40--------
    VAR_0692664
    ----see VAR_0692662 S L mis40--------
    VAR_0692634
    ----see VAR_0692632 A V mis40--------
    VAR_0692654
    ----see VAR_0692652 S R mis40--------
    rs1854743611,2
    --32148199(+) TGTTGC/GAATCC 4 -- us2k10--------
    rs1512711731,2
    --32148291(+) AGGCTC/GAGGCA 4 -- us2k10--------
    rs96213321,2
    C,F--32148300(+) cagaaG/Aaatca 4 -- us2k13Minor allele frequency- A:0.10NA WA 122
    rs1405218971,2
    --32148359(+) CACTGC/TAGCCT 4 -- us2k10--------
    rs602162171,2
    C--32148394(+) GGGGA-/AAAAAA 4 -- us2k10--------
    rs1903313081,2
    --32148450(+) GGAGGC/GCAAGG 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for DEPDC5 (32149937 - 32303020 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for DEPDC5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2513825CNV Deletion19546169
    esv2724143CNV Deletion23290073
    esv2670901CNV Deletion23128226
    nsv508731CNV Insertion20534489
    esv2575942CNV Insertion19546169
    nsv3595CNV Insertion18451855


    Human Gene Mutation Database (HGMD): DEPDC5
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614191    OMIM disorders: --

    UniProtKB/Swiss-Prot: DEPD5_HUMAN, O75140
  • Note=Familial focal epilepsy with variable foci (FFEVF): A syndrome characterized by mostly nocturnal
    seizures arising from frontal, temporal, and occasionally occipital epileptic foci. There is no evidence for
    structural brain damage or permanent neurologic dysfunction. The syndrome is inherited as an autosomal dominant
    trait with incomplete penetrance. The disease is caused by mutations affecting the gene represented in this entry

  • 3 diseases for DEPDC5:    About MalaCards
    hepatitis c    hepatocellular carcinoma    hepatitis


    DEPDC5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DEPDC5
    Human Genome Epidemiology (HuGE) Navigator: DEPDC5 (1 document)

    Export disorders for DEPDC5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DEPDC5 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with DEPDC5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations of DEPDC5 cause autosomal dominant focal epilepsies. (PubMed id 23542701)1, 2, 3 Ishida S.... Baulac S. (2013)
    2. Mutations in DEPDC5 cause familial focal epilepsy with variable foci. (PubMed id 23542697)1, 2, 3 Dibbens L.M....Scheffer I.E. (2013)
    3. Genome-wide association study of intelligence: additiv e effects of novel brain expressed genes. (PubMed id 22449649)1, 4 Loo S.K....Nelson S.F. (2012)
    4. Variation in the DEPDC5 locus is associated with prog ression to hepatocellular carcinoma in chronic hepatitis C virus carriers. (PubMed id 21725309)1, 4 Miki D....Chayama K. (2011)
    5. Complex chromosome 22 rearrangements in astrocytic tumors identified using microsatellite and chromosome 22 tile path array analysis. (PubMed id 15770670)1, 2 Seng T.J.... Collins V.P. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    8. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (1998)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Genetic associations of variants in genes encoding HI V-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9681 HGNC: 18423 AceView: DEPDC5 Ensembl:ENSG00000100150 euGenes: HUgn9681
    ECgene: DEPDC5 H-InvDB: DEPDC5

    (According to HUGE)
    About This Section
    HUGE: KIAA0645

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DEPDC5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DEPDC5 gene:
    Search GeneIP for patents involving DEPDC5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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