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DEPDC1B Gene

protein-coding   GIFtS: 50
GCID: GC05M059892

DEP Domain Containing 1B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEP Domain Containing 1B1 2     XTP12
Breast Cancer Cell 31 2     DEP Domain-Containing Protein 1B2
HBV X-Transactivated Gene 8 Protein2 3     HBxAg Transactivated Protein 12
HBV XAg-Transactivated Protein 82 3     XTP83
BRCC32     

External Ids:    HGNC: 249021   Entrez Gene: 557892   Ensembl: ENSG000000354997   UniProtKB: Q8WUY93   

Export aliases for DEPDC1B gene to outside databases

Previous GC identifers: GC05M059909 GC05M059928 GC05M056850


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DEPDC1B Gene:
DEPDC1B (DEP domain containing 1B) is a protein-coding gene. Diseases associated with DEPDC1B include breast cancer, and bronchiolitis. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is DEPDC4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_034772.7  
Regulatory elements:
   Regulatory transcription factor binding sites in the DEPDC1B gene promoter:
         Max1   p300   XBP-1   Meis-1b   E47   POU2F1   POU2F1a   Hand1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDEPDC1B promoter sequence
   Search Chromatin IP Primers for DEPDC1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DEPDC1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q12.1   Ensembl cytogenetic band:  5q12.1   HGNC cytogenetic band: 5q12

DEPDC1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEPDC1B gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M059892:  view genomic region     (about GC identifiers)

Start:
59,892,739 bp from pter      End:
59,996,017 bp from pter
Size:
103,279 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DEP1B_HUMAN, Q8WUY9 (See protein sequence)
Recommended Name: DEP domain-containing protein 1B  
Size: 529 amino acids; 61771 Da
Sequence caution: Sequence=AAH10904.1; Type=Erroneous initiation; Sequence=BAA91529.1; Type=Erroneous initiation;
Secondary accessions: A8K3R9 B4DUT4 Q86WJ3 Q8IZY6 Q9NUN3 Q9NW57
Alternative splicing: 2 isoforms:  Q8WUY9-1   Q8WUY9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DEPDC1B: NX_Q8WUY9

Explore proteomics data for DEPDC1B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DEPDC1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138680.1  NP_060839.2  

    ENSEMBL proteins: 
     ENSP00000265036   ENSP00000389101   ENSP00000427527   ENSP00000426979   ENSP00000438320  
    Reactome Protein details: Q8WUY9

    DEPDC1B Human Recombinant Protein Products:

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    Novus Biologicals DEPDC1B Proteins
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    Cloud-Clone Corp. Proteins for DEPDC1B

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    Abcam antibodies for DEPDC1B
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    LSBio Antibodies in human, mouse, rat for DEPDC1B

    DEPDC1B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for DEPDC1B
    Cloud-Clone Corp. CLIAs for DEPDC1B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR008936 Rho_GTPase_activation_prot
     IPR011991 WHTH_DNA-bd_dom
     IPR000591 DEP_dom
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q8WUY9

    ProtoNet protein and cluster: Q8WUY9

    2 Blocks protein domains:
    IPB000198 RhoGAP domain
    IPB000591 Pleckstrin putative G-protein interacting domain


    UniProtKB/Swiss-Prot: DEP1B_HUMAN, Q8WUY9
    Similarity: Contains 1 DEP domain
    Similarity: Contains 1 Rho-GAP domain


    DEPDC1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IEA--
         
    DEPDC1B for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DEPDC1B:
     Increased G1 DNA content  Increased cell size 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DEPDC1B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DEPDC1B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DEPDC1B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DEPDC1B

    miRNA
    Products:
        
    miRTarBase miRNAs that target DEPDC1B:
    hsa-mir-361-5p (MIRT020076)

    Block miRNA regulation of human, mouse, rat DEPDC1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DEPDC1B (see all 21):
    hsa-miR-3130-5p hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-128 hsa-miR-3129-5p hsa-miR-1297 hsa-miR-499-5p hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmidDEPDC1B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DEPDC1B
    Predesigned siRNA for gene silencing in human, mouse, rat DEPDC1B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DEPDC1B

    Clone
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    OriGene ORF clones in mouse, rat for DEPDC1B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DEPDC1B (NM_001145208)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DEPDC1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEPDC1B

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for DEPDC1B
    Browse ESI BIO Cell Lines and PureStem Progenitors for DEPDC1B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEPDC1B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus2
    golgi apparatus1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--

    DEPDC1B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DEPDC1B About    
    See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.58

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for DEPDC1B
        Rho GTPase cycle



    DEPDC1B for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DEPDC1B
    Interactions:

        Search GeneGlobe Interaction Network for DEPDC1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DEPDC1B (ENSP000002650364) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ECT2ENSP000002324584STRING: ENSP00000232458
    ARHGAP4ENSP000002037864STRING: ENSP00000203786
    ARHGDIAENSP000002693214STRING: ENSP00000269321
    ARHGDIBENSP000002289454STRING: ENSP00000228945
    ARHGDIGENSP000002194094STRING: ENSP00000219409
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    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0035556intracellular signal transduction ----
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    DEPDC1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DEPDC1B (DEP1B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DEPDC1B gene (2 alternative transcripts): 
    NM_001145208.1  NM_018369.2  

    Unigene Cluster for DEPDC1B:

    DEP domain containing 1B
    Hs.482233  [show with all ESTs]
    Unigene Representative Sequence: NM_018369
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265036(uc003jsh.3 uc011cqm.2 uc011cqn.2) ENST00000453022
    ENST00000512078 ENST00000509006 ENST00000505017 ENST00000512452 ENST00000545085

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DEPDC1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DEPDC1B (see all 21):
    hsa-miR-3130-5p hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-128 hsa-miR-3129-5p hsa-miR-1297 hsa-miR-499-5p hsa-miR-199b-5p
    SwitchGear 3'UTR luciferase reporter plasmidDEPDC1B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DEPDC1B
    Predesigned siRNA for gene silencing in human, mouse, rat DEPDC1B
    Clone
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    OriGene clones in human, mouse for DEPDC1B (see all 11)
    OriGene ORF clones in mouse, rat for DEPDC1B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DEPDC1B (NM_001145208)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DEPDC1B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEPDC1B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DEPDC1B
    OriGene qSTAR qPCR primer pairs in human, mouse for DEPDC1B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DEPDC1B
      QuantiTect SYBR Green Assays in human, mouse, rat DEPDC1B
      QuantiFast Probe-based Assays in human, mouse, rat DEPDC1B

    Additional mRNA sequence: 

    AF303178.1 AF488828.1 AF490257.1 AK001166.1 AK002114.1 AK290684.1 AK299242.1 AK300782.1 
    BC010904.1 BC019075.1 

    6 DOTS entries:

    DT.212838  DT.100751636  DT.91660149  DT.407195  DT.92045791  DT.425510 

    Selected AceView cDNA sequences (see all 84):

    BC010904 AW237743 BG503526 BG777843 AI094462 BG779247 BP359422 AA745250 
    AK001166 AA830503 AA916901 BM836122 BF732696 BQ437452 AA830747 BX100635 
    AF488828 AA644541 BM464432 AI376300 BI463837 BG498558 BM750446 AI141973 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DEPDC1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTTTATTA
    DEPDC1B Expression
    About this image


    DEPDC1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Epithelial Cells
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Lung (Respiratory System)
             Basal Cells Respiratory Bronchioles
     
     Eye (Sensory Organs)
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Placenta (Extraembryonic Tissues)
    DEPDC1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DEPDC1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.482233
        Custom PCR Arrays for DEPDC1B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for DEPDC1B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEPDC1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for DEPDC1B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Depdc1b1 , 5 DEP domain containing 1B1, 5 86.45(n)1
    93.95(a)1
      13 (59.69 cM)5
    2185811  NM_178683.41  NP_848798.11 
     1083163325 
    chicken
    (Gallus gallus)
    Aves DEPDC1B1 DEP domain containing 1B 74.35(n)
    75.43(a)
      427152  NM_001006576.1  NP_001006576.1 
    lizard
    (Anolis carolinensis)
    Reptilia DEPDC1B6
    DEP domain containing 1B
    75(a)
    1 ↔ 1
    2(9013733-9040247)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.139222 Xenopus laevis transcribed sequences 76.2(n)    CA789128.1 
    zebrafish
    (Danio rerio)
    Actinopterygii depdc1b6
    DEP domain containing 1B
    56(a)
    1 ↔ 1
    21(66816-72501) ENSDARG00000060507


    ENSEMBL Gene Tree for DEPDC1B (if available)
    TreeFam Gene Tree for DEPDC1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DEPDC1B gene
    DEPDC42  DEPDC12  DEPDC72  
    2 SIMAP similar genes for DEPDC1B using alignment to 4 protein entries:     DEP1B_HUMAN (see all proteins):
    DEPDC1    DKFZp434K0831

    DEPDC1B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DEPDC1B (see all 1839)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1830064501,2
    --59892319(+) TGGAAA/TGTAAG 2 -- int10--------
    rs737593601,2
    C,F--59892389(+) ATGTAG/AGAGGT 2 -- int12Minor allele frequency- A:0.12WA 120
    rs568145211,2
    C,F--59892899(+) ACTTTC/GCATTT 2 -- ut312Minor allele frequency- G:0.10WA 120
    rs1487704321,2
    --59893016(+) TCTGTC/TATAAC 2 -- ut310--------
    rs1415452031,2
    --59893126(+) TAATTA/GGCTAC 2 -- ut310--------
    rs68860851,2
    C,F,A,H--59893140(+) GTCAAT/CAGCAT 2 -- ut315Minor allele frequency- C:0.01NS EA NA 502
    rs1873055581,2
    --59893818(+) TTAAGA/CGTTTC 2 -- int10--------
    rs727551401,2
    C--59893962(+) CCCACC/TGCCAA 2 -- int10--------
    rs1443189851,2
    C--59894266(+) GTGTGA/G/TAATCC 2 -- int10--------
    rs1465375301,2
    --59894394(+) AAAAAC/TGATTC 2 -- int10--------

    HapMap Linkage Disequilibrium report for DEPDC1B (59892739 - 59996017 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for DEPDC1B (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv5002CNV Deletion18987735
    nsv436477CNV Deletion17901297
    esv2662567CNV Deletion23128226
    esv2658588CNV Deletion23128226
    esv2730241CNV Deletion23290073
    esv2730238CNV Deletion23290073
    esv2675953CNV Deletion23128226
    esv2730240CNV Deletion23290073
    nsv508362CNV Loss20534489
    nsv4850CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DEPDC1B
    DNA2.0 Custom Variant and Variant Library Synthesis for DEPDC1B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for DEPDC1B:    
    About MalaCards
    breast cancer    bronchiolitis    retinitis


    DEPDC1B for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: DEPDC1B (1 document)

    Export disorders for DEPDC1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DEPDC1B gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with DEPDC1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    4. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PubMed id 20923822)1 Niu N....Wang L. (Genome Res. 2010)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55789 HGNC: 24902 AceView: DEPDC1B Ensembl:ENSG00000035499 euGenes: HUgn55789
    ECgene: DEPDC1B H-InvDB: DEPDC1B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DEPDC1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DEPDC1B gene:
    Search GeneIP for patents involving DEPDC1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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