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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DENND5B Gene

protein-coding   GIFtS: 47
GCID: GC12M031535

DENN/MADD domain containing 5B
  Search for DENND5B
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DENND5B    

Aliases
for DENND5B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
DENN/MADD Domain Containing 5B1 2
Rab6IP1-Like Protein2 3
MGC240391
DENN Domain-Containing Protein 5B2

External Ids:    HGNC: 283381   Entrez Gene: 1605182   Ensembl: ENSG000001704567   UniProtKB: Q6ZUT93   

Export aliases for DENND5B gene to outside databases

Previous GC identifers: GC12M031426 GC12M031287


Summaries
for DENND5B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: DEN5B_HUMAN, Q6ZUT9
Function: Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of
GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form




Genomic Views
for DENND5B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DENND5B gene promoter:
         Pax-3   RP58   HNF-1   HNF-1A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DENND5B promoter sequence
   Search SABiosciences Chromatin IP Primers for DENND5B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND5B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11.21   Ensembl cytogenetic band:  12p11.21   HGNC cytogenetic band: 12p11.21

DENND5B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DENND5B gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M031535:  view genomic region     (about GC identifiers)

Start:
 31,535,157 bp from pter      End:
 31,744,031 bp from pter
Size:
 208,875 bases      Orientation:
 minus strand

Proteins
for DENND5B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DEN5B_HUMAN, Q6ZUT9 (See protein sequence)
Recommended Name: DENN domain-containing protein 5B  
Size: 1274 amino acids; 145020 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Sequence caution: Sequence=BAC04583.1; Type=Erroneous initiation;
Secondary accessions: B5ME75 Q59FW8 Q68CZ7 Q6NUJ0 Q7Z3F9 Q8N973 Q8WUC8
Alternative splicing: 4 isoforms:  Q6ZUT9-1   Q6ZUT9-2   Q6ZUT9-3   Q6ZUT9-4   

Explore the universe of human proteins at neXtProt for DENND5B: NX_Q6ZUT9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6ZUT9

    • DENND5B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_659410.3  
    ENSEMBL proteins: 
     ENSP00000373734   ENSP00000444889   ENSP00000346238   ENSP00000442938   ENSP00000445113  
     ENSP00000306482  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: DENND5B
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    Novus Biologicals DENND5B Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DENND5B

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    DENND5B for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DENND5B

    Protein Domains /
    Families
    for DENND5B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DENND5B for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR001024 LipOase_LH2
     IPR005113 uDENN_dom
     IPR008976 Lipase_LipOase
     IPR005112 dDENN_dom
     IPR001194 DENN_dom

    Graphical View of Domain Structure for InterPro Entry Q6ZUT9

    ProtoNet protein and cluster: Q6ZUT9

    1 Blocks protein family: IPB001024 Lipoxygenase

    UniProtKB/Swiss-Prot: DEN5B_HUMAN, Q6ZUT9
    Similarity: Belongs to the RAB6IP1 family
    Similarity: Contains 1 dDENN domain
    Similarity: Contains 1 DENN domain
    Similarity: Contains 1 PLAT domain
    Similarity: Contains 2 RUN domains
    Similarity: Contains 1 uDENN domain


    Function
    for DENND5B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DEN5B_HUMAN, Q6ZUT9
    Function: Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of
    GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form

    miRNA
    Products:            		 OriGene 3'-UTR Clone: DENND5B
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DENND5B
    8/129 QIAGEN miScript miRNA Assays for microRNAs that regulate DENND5B (see all 129):
    hsa-miR-579 hsa-miR-520e hsa-miR-3607-3p hsa-miR-520f hsa-miR-4254 hsa-miR-193a-3p hsa-miR-607 hsa-miR-106a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DENND5B
    OriGene shRNA RFP: DENND5B
    OriGene siRNA: DENND5B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DENND5B

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DENND5B

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DENND5B (see all 2)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DENND5B 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for DENND5B
    Search LifeMap BioReagents cell lines for DENND5B

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND5B

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017112Rab guanyl-nucleotide exchange factor activity IDA--


    DENND5B for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for DENND5B:
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 


    Pathways & Interactions
    for DENND5B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DENND5B

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for DENND5B (ENSP000003737344) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Drugs & Compounds
    for DENND5B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DENND5B
    Search CenterWatch for drugs/clinical trials and news about DENND5B / DEN5B 

    Transcripts
    for DENND5B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DENND5B gene: 
    NM_144973.3  

    Unigene Cluster for DENND5B:

    DENN/MADD domain containing 5B
    Hs.118166  [show with all ESTs]
    Unigene Representative Sequence: NM_144973
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389082(uc001rki.1) ENST00000536562 ENST00000537061 ENST00000354285(uc001rkj.3)
    ENST00000546299(uc001rkk.1) ENST00000545147 ENST00000544698 ENST00000306833(uc001rkh.1)


    miRNA
    Products:             		 OriGene 3'-UTR Clone: DENND5B
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DENND5B
    8/129 QIAGEN miScript miRNA Assays for microRNAs that regulate DENND5B (see all 129):
    hsa-miR-579 hsa-miR-520e hsa-miR-3607-3p hsa-miR-520f hsa-miR-4254 hsa-miR-193a-3p hsa-miR-607 hsa-miR-106a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DENND5B
    OriGene shRNA RFP: DENND5B
    OriGene siRNA: DENND5B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DENND5B
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DENND5B (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DENND5B
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    GenScript: all cDNA clones in your preferred vector: DENND5B (NM_144973)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DENND5B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DENND5B 
    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DENND5B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DENND5B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND5B

    Additional cDNA sequence: 

    AB209341.1 AF086301.1 AK021465.1 AK095598.1 AK123642.1 AK125323.1 AL137364.1 BC020855.1 
    BC068580.1 BX537924.1 CR749639.1 

    8 DOTS entries:

    DT.100020808  DT.101982607  DT.75100860  DT.40114261  DT.100843629  DT.91699202  DT.109793  DT.435097 

    24/63 AceView cDNA sequences (see all 63):

    AI357112 BX102275 AI970335 BC020855 AI078518 NM_144973 AL045354 AI219445 
    BU429490 AW183698 AK125323 BU162323 AK095598 BX385511 AW136535 BF796979 
    BG201391 AI539456 CB043856 BU950547 AU117123 BV190756 AI252660 CR749639 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for DENND5B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:                                                        -                       -     -                                                                     
    SP2:        -     -                                         -                                                                                                   
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  


    ECgene alternative splicing isoforms for DENND5B

    Expression
    for DENND5B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DENND5B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTTGTTCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DENND5B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TestisSeminiferous TubulesSecondary SpermatocyteGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DENND5B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DENND5B

    SOURCE GeneReport for Unigene cluster: Hs.118166
        SABiosciences Custom PCR Arrays for DENND5B
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND5B
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND5B

    Orthologs
    for DENND5B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DENND5B gene from 8/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves DENND5B1 DENN/MADD domain containing 5B 80.48(n)
    92.12(a)    		   418139  XM_003640399.1  XP_003640447.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DENND5B6
    		 --
    		 91(a)
    		 1 ↔ 1
    		 5(10746638-10795472)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.109852 Transcribed sequence with weak similarity to protein more 79.1(n)    AL854717.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufb96b012 Transcribed sequence with moderate similarity to protein more 76.49(n)    AI497102.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG78526
    		 --
    		 38(a)
    		 1 → many
    		 3L(1537137-1544823)
    worm
    (Caenorhabditis elegans)    		 Secernentea C52E12.46
    		 Protein C52E12.4
    		 31(a)
    		 1 → many
    		 II(7012753-7022467)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SCD16
    		 stomatal cytokinesis defective / SCD1 protein (SCD...
    		 10(a)
    		 possible ortholog
    		 1(18139234-18148981)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 SCD1, putative, expressed
    		 9(a)
    		 possible ortholog
    		 1(22162051-22179384)


    ENSEMBL Gene Tree for DENND5B (if available)
    TreeFam Gene Tree for DENND5B (if available) 

    Paralogs
    for DENND5B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DENND5B gene
    ST52  DENND5A2  DENND2D2  DENND2A2  DENND32  DENND4A2  DENND1C2  DENND4B2  
    DENND1B2  DENND1A2  DENND4C2  DENND2C2  
    8 SIMAP similar genes for DENND5B using alignment to 4 protein entries:     DEN5B_HUMAN (see all proteins):
    MGC24039    DENND5A    OK/SW-cl.41    KIAA1651    DNAPTP3    FP6651
    MADD    ST5

    DENND5B for paralogs           About GeneDecksing



    Genomic Variants
    for DENND5B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3850 NCBI SNPs in DENND5B are shown (see all 3850)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs113402351,2
    		C--31308124(+) TTTTC-/TTTTTT 1 -- int1 trp31Minor allele frequency- T:0.00NA 2
    rs1459859381,2
    		--31534658(+) CAGCTA/CATTTT 1 -- int10--------
    rs562068081,2
    		C,F,--31534802(+) TGATGA/CCCAGA 1 -- int13Minor allele frequency- C:0.07WA 122
    rs1910875171,2
    		--31534956(+) AAAAAC/TTATGT 1 -- int10--------
    rs2020002221,2
    		C,--31535020(+) GTGTG-/AGGT  
                AGGGT     		1 -- int10--------
    rs1829845161,2
    		--31535047(+) CCTTAC/TTCAGA 1 -- int10--------
    rs1386845441,2
    		--31535113(+) TCTTAC/TCCTAT 1 -- int10--------
    rs1418187571,2
    		--31535240(+) ACCCAC/TGTCAG 1 -- ut310--------
    rs1462655691,2
    		--31535277(+) TTAATA/GTCACA 1 -- ut310--------
    rs1875649721,2
    		--31535354(+) ACAATA/CCAAAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DENND5B (31535157 - 31744031 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for DENND5B
         8 CNVs: 86304 71486 86305 86302 5663 8717 86303 75997

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DENND5B
    DNA2.0 Custom Variant and Variant Library Synthesis for DENND5B

    Disorders / Diseases
    for DENND5B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DENND5B for disorders           About MalaCards

    DENND5B for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: DENND5B (1 document)

    Export disorders for DENND5B gene to outside databases

    Publications
    for DENND5B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DENND5B gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with DENND5B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)2 Yoshimura S.... Barr F.A. (2010)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    External Searches for DENND5B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing DENND5B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 160518 HGNC: 28338 AceView: MGC24039 Ensembl:ENSG00000170456 euGenes: HUgn160518
    ECgene: DENND5B H-InvDB: DENND5B

    Other Databases showing DENND5B gene

    (According to HUGE)
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    Specialized Databases showing DENND5B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DENND5B Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DENND5B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for DENND5B gene:
    Search GeneIP for patents involving DENND5B

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