DENND4C Gene
protein-coding GIFtS: 40
GCID: GC09P019289
|
|
DENN/MADD domain containing 4C(Previous names: chromosome 9 open reading frame 55B, chromosome 9 open...) (Previous symbols: C9orf55B, C9orf55)
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Aliases for DENND4C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| DENN/MADD Domain Containing 4C1 2 | | Chromosome 9 Open Reading Frame 551 | | C9orf551 2 3 | | Chromosome 9 Open Reading Frame 55B1 | | C9orf55B1 2 3 | | DENN Domain-Containing Protein 4C2 | | BA513M16.31 | | DENN/MADD Domain Containing 4A Pseudogene2 | | FLJ206861 | | |
Export aliases for DENND4C gene to outside databasesPrevious GC identifers: GC09P019281 GC09P019252 |
Summaries for DENND4C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: DEN4C_HUMAN, Q5VZ89Function: Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, convertinginactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enrichedvesicles delivery to the plasma membrane in response to insulin
|
Genomic Views for DENND4C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DENND4C gene promoter: AREB6 ISGF-3 AML1a GATA-6 FOXF2 FOXJ2 (long isoform) HFH-1 FOXJ2 Ik-3 c-Ets-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for DENND4C
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND4C |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p22.1 Ensembl cytogenetic band: 9p22.1 HGNC cytogenetic band: 9p22.1DENND4C Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P019289: view genomic region
(about GC identifiers)
Start:
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19,288,622 bp from pter |
End:
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19,374,275 bp from pter |
Size:
|
85,654 bases |
Orientation:
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plus strand |
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Proteins for DENND4C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: DEN4C_HUMAN, Q5VZ89 (See
protein sequence)Recommended Name: DENN domain-containing protein 4C Size: 1673 amino acids; 186857 Da
Subcellular location: Cytoplasmic vesicle membrane. Cell membrane. Cytoplasm, cytosol. Note=Associates withSLC2A4/GLUT4 storage vesicles
Sequence caution: Sequence=BAA91294.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA91478.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA92039.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB15221.1; Type=Erroneous initiation;Note=Translation N-terminally extended; Sequence=CAH10466.1; Type=Erroneous initiation; Note=Translation N-terminallyextended; Sequence=CAM21141.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A2A3R1 A2A3R2 A2A3R3 A2A3R9 Q6AI48 Q6ZUB3 Q8NCY7 Q9H6N4 Q9NUT1 Q9NWA5 Q9NWT3Alternative splicing: 6 isoforms: Q5VZ89-1 Q5VZ89-2 Q5VZ89-3 Q5VZ89-4 Q5VZ89-5 Q5VZ89-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DENND4C: NX_Q5VZ89
Post-translational modifications:
Phosphorylated in response to insulin (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VZ89 DENND4C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060395.5 ENSEMBL proteins: ENSP00000369802 ENSP00000369797 ENSP00000369792 ENSP00000354301 ENSP00000369789 ENSP00000305795 ENSP00000443804 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
DENND4C for ontologies About GeneDecksing
DENND4C Antibody Products: Assay Products for DENND4C: |
Protein
Domains / Families for DENND4C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DENND4C for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5VZ89ProtoNet protein and cluster: Q5VZ89 UniProtKB/Swiss-Prot: DEN4C_HUMAN, Q5VZ89Similarity: Contains 1 dDENN domainSimilarity: Contains 1 DENN domainSimilarity: Contains 1 PPR (pentatricopeptide) repeatSimilarity: Contains 1 uDENN domain |
Function for DENND4C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: DEN4C_HUMAN, Q5VZ89Function: Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, convertinginactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enrichedvesicles delivery to the plasma membrane in response to insulin
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DENND4C (NM_017925) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DENND4C | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DENND4C  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND4C |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity |
IDA | -- |
DENND4C for ontologies About GeneDecksing
|
Pathways & Interactions for DENND4C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DENND4C
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
 2 Interacting proteins for DENND4C (Q5VZ893 ENSP000003698024) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015031 | protein transport |
IEA | -- | | GO:0032869 | cellular response to insulin stimulus |
ISS | -- | | GO:0072659 | protein localization to plasma membrane |
ISS | -- |
DENND4C for ontologies About GeneDecksing
|
Drugs & Compounds for DENND4C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for DENND4C Search CenterWatch for drugs/clinical trials and news about DENND4C / DEN4C 
|
Transcripts for DENND4C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for DENND4C gene: NM_017925.5 Unigene Cluster for DENND4C: DENN/MADD domain containing 4C Hs.249591 [show with all ESTs]Unigene Representative Sequence: NM_0179258 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000494124 ENST00000380437 ENST00000380432 ENST00000380427(uc003znt.3) ENST00000361024 ENST00000380424 ENST00000307015(uc003znr.3 uc003znq.3 uc011lnc.2 uc011lnd.2 uc003zns.3) ENST00000540671
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DENND4C (NM_017925) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DENND4C | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DENND4C  |
Additional cDNA sequence: AK000627.1 AK000693.1 AK001046.1 AK002020.1 AK025705.1 AK125842.1 AK127734.1 AK299842.1 AK302901.1 AL834521.1 BC144484.1 BC144485.1 CR627367.1 NR_073201.1 15 DOTS entries: DT.97838739 DT.214521 DT.410018 DT.121149839 DT.100784968 DT.40217577 DT.70101132 DT.121149867 DT.121149910 DT.121149931 DT.439289 DT.91972220 DT.92014101 DT.99999363 DT.92047754 2 AceView cDNA sequences: N28227 BG197754 GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for DENND4C (see all 9) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | ^ | 18a | · | 18b | · | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 18c | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | |
| SP1: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for DENND4C
|
Expression for DENND4C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DENND4C expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See DENND4C Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DENND4C
SOURCE GeneReport for Unigene cluster: Hs.249591 SABiosciences Custom PCR Arrays for DENND4C
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DENND4C Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DENND4C | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DENND4C | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND4C | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND4C |
Orthologs for DENND4C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DENND4C gene from 8/24 species (see all 24) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
DENND4C1 |
DENN/MADD domain containing 4C |
74.78(n) 77.42(a) |
  |
427236 XM_424821.3 XP_424821.3 |
lizard (Anolis carolinensis) |
Reptilia |
DENND4C6 |
-- |
64(a) |
1 ↔ 1 |
2(62476030-62552438) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
Str.160122 |
Transcribed sequence with weak similarity to protein more |
74.18(n) |
  |
142033743 |
zebrafish (Danio rerio) |
Actinopterygii |
LOC5586261 |
similar to DENN/MADD domain containing 4C |
63.34(n) 66.04(a) |
  |
558626 XM_001919955.3 XP_001919990.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Crag6 |
Calmodulin-binding protein related to a Rab3 GDP/G... |
26(a) |
1 → many |
X(8486086-8495264) |
worm (Caenorhabditis elegans) |
Secernentea |
F52C12.41 |
Protein F52C12.4 |
49.12(n) 41.9(a) |
  |
186100 NM_067744.2 NP_500145.2 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
SCD16 |
stomatal cytokinesis defective / SCD1 protein (SCD... |
10(a) |
possible ortholog |
1(18139234-18148981) |
rice (Oryza sativa) |
Liliopsida |
-- |
SCD1, putative, expressed |
10(a) |
possible ortholog |
1(22162051-22179384) |
ENSEMBL Gene Tree for DENND4C (if available) TreeFam Gene Tree for DENND4C (if available)  |
Paralogs for DENND4C gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for DENND4C gene
- ST52 DENND5A2 DENND2D2 DENND2A2 DENND32 DENND4A2 DENND1C2 DENND4B2
- DENND1B2 DENND1A2 DENND5B2 DENND2C2
2 SIMAP similar genes for DENND4C using alignment to 2 protein entries: DEN4C_HUMAN (see all proteins):DENND4A DENND4B
DENND4C for paralogs About GeneDecksing
|
Genomic Variants for DENND4C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 9 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for DENND4C (19288622 - 19374275 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for DENND4C 3 CNVs: 65351 95870 52762  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DENND4C |
|
Disorders
/ Diseases for DENND4C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications for DENND4C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DENND4C gene, integrated from 9 sources (see all 19): (articles sorted by number of sources associating them with DENND4C) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges. (PubMed id 12906859)1, 3 Semova N....Semov A. (2003)
- Insulin-stimulated GLUT4 protein translocation in adi pocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. (PubMed id 21454697)1 Sano H....Lienhard G.E. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for DENND4C gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DENND4C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DENND4C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DENND4C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for DENND4C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DENND4C gene: Search GeneIP for patents involving DENND4C
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for DENND4C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for DENND4C | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DENND4C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DENND4C | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for DENND4C | | OriGene 3'-UTR Clone for DENND4C | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DENND4C | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for DENND4C | | OriGene Custom Protein Services for DENND4C | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DENND4C | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DENND4C | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND4C | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DENND4C | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND4C | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DENND4C |
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| | | Search Tocris compounds for DENND4C |
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 | | DENND4C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND4C |
|  |  |  | | | Search ThermoFisher Antibodies for DENND4C |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DENND4C |
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