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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DENND4A Gene

protein-coding GIFtS: 49
GCID: GC15M065952

DENN/MADD domain containing 4A

(Previous name: c-myc promoter binding protein )
(Previous symbol: MYCPBP)

Explore 1 disease affiliated with
DENND4A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
DENN/MADD Domain Containing 4A¹ ²
IRLB¹ ² ³
MYCPBP¹ ² ³
C-Myc Promoter Binding Protein¹ ²
DENN Domain-Containing Protein 4A² ³
C-Myc Promoter-Binding Protein²

External Ids:	HGNC: 24321¹	Entrez Gene: 10260²	Ensembl: ENSG00000174485⁷	OMIM: 600382⁵	UniProtKB: Q7Z401³

Export aliases for DENND4A gene to outside databases

Previous GC identifers: GC15M063741 GC15M042779

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MYCPP_HUMAN, Q7Z401

Function: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to

GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may

bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter

Gene Wiki entry for DENND4A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000015.9 NC_018926.1 NT_010194.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DENND4A gene promoter:
AML1a HOXA3 Sp1 MEF-2 RORalpha2 AREB6 MEF-2A aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DENND4A promoter sequence

Search SABiosciences Chromatin IP Primers for DENND4A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND4A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.31 Ensembl cytogenetic band: 15q22.31 HGNC cytogenetic band: 15q22.31

DENND4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DENND4A gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15M065952: view genomic region (about GC identifiers)

Start:	65,950,384 bp from pter	End:	66,084,631 bp from pter
Size:	134,248 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MYCPP_HUMAN, Q7Z401 (See protein sequence)

Recommended Name: C-myc promoter-binding protein

Size: 1863 amino acids; 209244 Da

Subcellular location: Nucleus (Probable)

Developmental stage: Highly expressed in fetal liver

Sequence caution: Sequence=AL833317; Type=Frameshift; Positions=1774;

Secondary accessions: E7EPL3 Q14655 Q86T77 Q8IVX2 Q8NB93

Alternative splicing: 2 isoforms: Q7Z401-1 Q7Z401-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DENND4A: NX_Q7Z401

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q7Z401

DENND4A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001138295.1 NP_005839.3

ENSEMBL proteins:

ENSP00000456605 ENSP00000391167 ENSP00000396830 ENSP00000457358

Human Recombinant Protein Products for DENND4A:

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	Uscn Proteins for DENND4A

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	--

DENND4A for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for DENND4A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DENND4A for domains About GeneDecksing

5 InterPro domains/families:

IPR005113 uDENN_dom

IPR005112 dDENN_dom

IPR001194 DENN_dom

IPR002885 Pentatricopeptide_repeat

IPR023341 MABP

Graphical View of Domain Structure for InterPro Entry Q7Z401

ProtoNet protein and cluster: Q7Z401

UniProtKB/Swiss-Prot: MYCPP_HUMAN, Q7Z401

Similarity: Contains 1 dDENN domain

Similarity: Contains 1 DENN domain

Similarity: Contains 1 MABP domain

Similarity: Contains 2 PPR (pentatricopeptide) repeats

Similarity: Contains 1 uDENN domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MYCPP_HUMAN, Q7Z401

Function: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to

GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may

bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter

Induction: By serum in low-passage fibroblasts

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	NAS	8056341
GO:0017112	Rab guanyl-nucleotide exchange factor activity	IDA	--

DENND4A for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for DENND4A:

Actin fiber cells

Increased S DNA content

Increased homologous recombina

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DENND4A

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		hsa-miR-579 hsa-miR-520d-5p hsa-miR-15a hsa-miR-503 hsa-miR-374a hsa-miR-10b* hsa-miR-374c hsa-miR-1184

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND4A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DENND4A

5/10 Interacting proteins for DENND4A (Q7Z401^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAG	P61981²^,³	MINT-50898 I2D: score=4
YWHAB	P31946²^,³	MINT-50997 I2D: score=3
YWHAZ	P63104²^,³	MINT-3320063 I2D: score=1
YWHAQ	P27348³	I2D: score=2
CEBPE	Q15744³	I2D: score=1

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	NAS	8056341

DENND4A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DENND4A
Search CenterWatch for drugs/clinical trials and news about DENND4A / MYCPP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DENND4A gene (2 alternative transcripts):

NM_001144823.1 NM_005848.3

Unigene Cluster for DENND4A:

DENN/MADD domain containing 4A

Hs.654567 [show with all ESTs]

Unigene Representative Sequence: NM_001144823

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000561863 ENST00000443035(uc002api.3 uc002aph.3 uc002apj.3)

ENST00000431932 ENST00000562540 ENST00000567323 ENST00000564674 ENST00000562028

ENST00000568515(uc010ujj.1)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DENND4A
		8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate DENND4A (see all 28):
		hsa-miR-579 hsa-miR-520d-5p hsa-miR-15a hsa-miR-503 hsa-miR-374a hsa-miR-10b* hsa-miR-374c hsa-miR-1184

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Additional cDNA sequence:

AF534403.1 AK091268.1 AK091368.1 AK290292.1 AK299570.1 AK307411.1 AL832602.2 AL833317.1

AL833384.1 BC028057.1 BC041706.1 X63417.1

6 DOTS entries:

DT.422698 DT.97838411 DT.92061312 DT.92061311 DT.100024571 DT.91805594

24/104 AceView cDNA sequences (see all 104):

CK300924 AA765298 BX495425 BC041706 BM718270 AF534403 CB069125 AW501527

BC028057 N50598 AW501539 BU102007 CK904100 AL832602 AX746940 CK904099

AI628351 BU845366 NM_005848 BQ721664 BU431382 AW501229 AW500927 BU633382

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DENND4A (see all 6) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15a	·	15b	^	16	^	17	^	18	^	19	^	20	^	21a	·	21b	^	22	^
SP1:																																	-
SP2:							-																										-												-
SP3:																																	-												-
SP4:
SP5:

ExUns:	23a	·	23b	^	24	^	25	^	26	^	27	^	28	^	29	^	30	^	31	^	32a	·	32b	^	33	^	34a	·	34b	·	34c
SP1:					-																-
SP2:					-																-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for DENND4A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DENND4A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGTTGTATT

About this image

DENND4A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Myocardium

Cardiac Fibroblasts

Epicardium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DENND4A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DENND4A

SOURCE GeneReport for Unigene cluster: Hs.654567

UniProtKB/Swiss-Prot: MYCPP_HUMAN, Q7Z401

Tissue specificity: Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes

and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells.

Expression is regulated in a growth- and cell cycle-dependent manner

SABiosciences Expression via Pathway-Focused PCR Arrays including DENND4A:

Necrosis in human mouse rat

Cell Death PathwayFinder in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DENND4A gene from 8/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DENND4A¹	DENN/MADD domain containing 4A	77.1(n) 80.79(a)		415541 XM_413911.3 XP_413911.3
lizard (Anolis carolinensis)	Reptilia	DENND4A⁶	--	76(a)	1 ↔ 1	GL343503.1(294838-349053)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.19491²	Transcribed sequence with weak similarity to protein more	72.67(n)		AL867989.2
zebrafish (Danio rerio)	Actinopterygii	dennd4a¹	DENN/MADD domain containing 4A	61.75(n) 64.46(a)		558211 NM_001080989.2 NP_001074458.1
fruit fly (Drosophila melanogaster)	Insecta	Crag¹	Calmodulin-binding protein related to a Rab3 GDP/GTP more	48.15(n) 46.13(a)		31800 NM_080341.3 NP_525080.3
worm (Caenorhabditis elegans)	Secernentea	F52C12.4⁶	Protein F52C12.4	29(a)	1 → many	IV(1923571-1946203)
thale cress (Arabidopsis thaliana)	eudicotyledons	SCD1⁶	stomatal cytokinesis defective / SCD1 protein (SCD...	11(a)	possible ortholog	1(18139234-18148981)
rice (Oryza sativa)	Liliopsida	--	SCD1, putative, expressed	10(a)	possible ortholog	1(22162051-22179384)

ENSEMBL Gene Tree for DENND4A (if available)
TreeFam Gene Tree for DENND4A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DENND4A gene

ST5² DENND5A² DENND2D² DENND2A² DENND3² DENND1C² DENND4B² DENND1B²

DENND1A² DENND5B² DENND4C² DENND2C²

2 SIMAP similar genes for DENND4A using alignment to 4 protein entries: MYCPP_HUMAN (see all proteins):

DENND4C DENND4B

DENND4A for paralogs About GeneDecksing

3 Pseudogenes.org Pseudogenes for DENND4A
PGOHUM00000262226 PGOHUM00000249559 PGOHUM00000236399

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs141094852^1,2		--	65952560(+)	`GCAAGG/TTCAGC`	2	--	ds500¹		0	--	--	--	--
rs192866794^1,2		--	65952742(+)	`AGTGTC/TGTGGA`	2	--	ds500¹		0	--	--	--	--
rs80093582^1,2	C	--	65952767(+)	`TACACC/TTAATT`	2	--	ds500¹		2		NA	122
rs79607088^1,2	C,F	--	65952890(+)	`AAAGAT/AGTTTT`	2	--	ds500¹		1		NA	120
rs138112288^1,2	C	--	65952951(+)	`AAAAT-/ATATTT`	2	--	ds500¹		0	--	--	--	--
rs905733^1,2	C,H	--	65953002(-)	`ATCAGA/CCAATA`	2	--	ut3¹		10		EA NA MN NS	664
rs150281235^1,2		--	65953208(+)	`ATTCTA/GTAGTA`	2	--	ut3¹		0	--	--	--	--
rs80233962^1,2	C	--	65953322(+)	`TTAAAA/CTTTAA`	2	--	ut3¹		2		CSA WA	119
rs116431545^1,2		--	65953371(+)	`TATACG/ATATCT`	2	--	ut3¹		1		WA	118
rs138948562^1,2		--	65953851(+)	`TTCATG/TATTTT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DENND4A (65950384 - 66084631 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DENND4A
1 CNV: 58732
1 Inversion: 59728

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DENND4A

DNA2.0 Custom Variant and Variant Library Synthesis for DENND4A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DENND4A for disorders           About GeneDecksing

OMIM gene information: 600382    OMIM disorders: --

1 disease for DENND4A:    About MalaCards

prostatitis

Export disorders for DENND4A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for DENND4A gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with DENND4A)

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Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges. (PubMed id 12906859)^{1, 2, 3, 9} Semova N....Semov A. (2003)
Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element. (PubMed id 8056341)^{1, 2, 3, 9} Stasiv Y.Z....Kisselev L.L. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)² Yoshimura S.... Barr F.A. (2010)
An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)¹ Ravasi T....Hayashizaki Y. (2010)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10260	HGNC: 24321	AceView: MYCPBP	Ensembl:ENSG00000174485	euGenes: HUgn10260
ECgene: DENND4A	H-InvDB: DENND4A

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for DENND4A	Pharmacogenomics, SNPs, Pathways

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Patent Information for DENND4A gene:
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