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DENND2D Gene

protein-coding   GIFtS: 48
GCID: GC01M111729

DENN/MADD Domain Containing 2D

  Search for DENND2D
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DENN/MADD Domain Containing 2D1 2
RP5-1180E21.22
DENN Domain-Containing Protein 2D2

External Ids:    HGNC: 261921   Entrez Gene: 799612   Ensembl: ENSG000001627777   OMIM: 6151115   UniProtKB: Q9H6A03   

Export aliases for DENND2D gene to outside databases

Previous GC identifers: GC01M111442 GC01M111531 GC01M109601


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DENND2D Gene:
DENND2D (DENN/MADD domain containing 2D) is a protein-coding gene. GO annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is ST5.

UniProtKB/Swiss-Prot: DEN2D_HUMAN, Q9H6A0
Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of
GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DENND2D gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   POU2F2   AREB6   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDENND2D promoter sequence
   Search Chromatin IP Primers for DENND2D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DENND2D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.3   Ensembl cytogenetic band:  1p13.3   HGNC cytogenetic band: 1p13.3

DENND2D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DENND2D gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M111729:  view genomic region     (about GC identifiers)

Start:
111,729,796 bp from pter      End:
111,747,157 bp from pter
Size:
17,362 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DEN2D_HUMAN, Q9H6A0 (See protein sequence)
Recommended Name: DENN domain-containing protein 2D  
Size: 471 amino acids; 53672 Da
Secondary accessions: Q5T5V6 Q9BSU0
Alternative splicing: 2 isoforms:  Q9H6A0-1   Q9H6A0-2   

Explore the universe of human proteins at neXtProt for DENND2D: NX_Q9H6A0

Explore proteomics data for DENND2D at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DENND2D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001258762.1  NP_079177.2  

    ENSEMBL proteins: 
     ENSP00000350266   ENSP00000358767  

    DENND2D Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for DENND2D 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DENND: DENN/MADD domain containing

    3 InterPro protein domains:
     IPR005112 dDENN_dom
     IPR005113 uDENN_dom
     IPR001194 DENN_dom

    Graphical View of Domain Structure for InterPro Entry Q9H6A0

    ProtoNet protein and cluster: Q9H6A0

    UniProtKB/Swiss-Prot: DEN2D_HUMAN, Q9H6A0
    Similarity: Contains 1 dDENN domain
    Similarity: Contains 1 DENN domain
    Similarity: Contains 1 uDENN domain


    Find genes that share domains with DENND2D           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DEN2D_HUMAN, Q9H6A0
    Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of
    GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017112Rab guanyl-nucleotide exchange factor activity IDA--
         
    Find genes that share ontologies with DENND2D           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for DENND2D:
     Decreased nuclei size in G2M  Increased circadian rhythm amp 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DENND2D
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DENND2D
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DENND2D

    miRNA
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    miRTarBase miRNAs that target DENND2D:
    hsa-mir-124-3p (MIRT022403)

    Block miRNA regulation of human, mouse, rat DENND2D using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate DENND2D:
    hsa-miR-140-3p hsa-miR-597 hsa-miR-197
    SwitchGear 3'UTR luciferase reporter plasmidDENND2D 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DENND2D

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DEN2D_HUMAN, Q9H6A0: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    endoplasmic reticulum1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with DENND2D           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DENND2D
    Interactions:

        Search GeneGlobe Interaction Network for DENND2D

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032313regulation of Rab GTPase activity IDA--

    Find genes that share ontologies with DENND2D           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DENND2D (DEN2D)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DENND2D gene (2 alternative transcripts): 
    NM_001271833.1  NM_024901.4  

    Unigene Cluster for DENND2D:

    DENN/MADD domain containing 2D
    Hs.557850  [show with all ESTs]
    Unigene Representative Sequence: NM_024901
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000468692 ENST00000357640(uc001eak.1) ENST00000369752(uc001eal.1)
    ENST00000473682 ENST00000463713 ENST00000477586 ENST00000473822 ENST00000488786

    miRNA
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    Block miRNA regulation of human, mouse, rat DENND2D using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate DENND2D:
    hsa-miR-140-3p hsa-miR-597 hsa-miR-197
    SwitchGear 3'UTR luciferase reporter plasmidDENND2D 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for DENND2D
    Predesigned siRNA for gene silencing in human, mouse, rat DENND2D
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    GenScript: all cDNA clones in your preferred vector: DENND2D (NM_024901)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DENND2D
    Primer
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    OriGene qPCR primer pairs and template standards for DENND2D
    OriGene qSTAR qPCR primer pairs in human, mouse for DENND2D
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DENND2D
      QuantiTect SYBR Green Assays in human, mouse, rat DENND2D
      QuantiFast Probe-based Assays in human, mouse, rat DENND2D

    Additional mRNA sequence: 

    AK026110.1 AK301583.1 BC004557.2 

    15 DOTS entries:

    DT.410602  DT.95272114  DT.100873339  DT.95272110  DT.444662  DT.91906248  DT.121409399  DT.92430109 
    DT.97845084  DT.92430107  DT.100800397  DT.97844567  DT.100697992  DT.121409460  DT.91963607 

    Selected AceView cDNA sequences (see all 218):

    AI394030 BF062413 AW015284 BX415728 BM755313 BG744860 AI283540 AL043121 
    AK026110 AI635421 CA311009 AW235262 BX096184 BQ029318 BX348771 AI224419 
    AV651615 AV646073 BE901433 BU188661 BQ030049 AA725483 CA436842 AW269278 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DENND2D (see all 14)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^
    SP1:                                      -     -     -     -     -     -                                   -     -     -     -                             -   
    SP2:                                                        -     -     -                                   -     -     -     -                             -   
    SP3:                                      -     -     -     -     -     -                                   -     -     -     -           -                     
    SP4:                    -     -     -     -           -     -     -     -                                   -     -     -     -                                 
    SP5:                                            -     -     -     -     -                                   -     -     -     -                                 

    ExUns: 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b
    SP1:                    -                                 
    SP2:                    -                                 
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for DENND2D

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DENND2D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGGACGAG
    DENND2D Expression
    About this image


    DENND2D expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Body Subcutaneous White Adipose
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Tonsil (Hematopoietic System)
     
     Spleen (Hematopoietic System)
    DENND2D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DENND2D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.557850

    UniProtKB/Swiss-Prot: DEN2D_HUMAN, Q9H6A0
    Tissue specificity: In bronchial mucosa, mainly expressed in ciliated and basal epithelial cells and weakly in
    alveolar cells (at protein level). Tends to be down-regulated in lung cancers, immortalized bronchial epithelial
    cell lines and precancerous lesions

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND2D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for DENND2D gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dennd2d1 , 5 DENN/MADD domain containing 2D1, 5 86.16(n)1
    90.54(a)1
      3 (46.49 cM)5
    721211  NM_001093754.21  NP_001087223.11 
     1064824055 
    chicken
    (Gallus gallus)
    Aves DENND2D1 DENN/MADD domain containing 2D 70.58(n)
    71.13(a)
      421153  XM_419235.4  XP_419235.4 
    lizard
    (Anolis carolinensis)
    Reptilia DENND2D6
    DENN/MADD domain containing 2D
    65(a)
    1 ↔ 1
    4(133062201-133096233)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BG512350.12   -- 73.44(n)    BG512350.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dennd2da1 DENN/MADD domain containing 2Da 59.27(n)
    55.6(a)
      768151  NM_001077294.1  NP_001070762.1 


    ENSEMBL Gene Tree for DENND2D (if available)
    TreeFam Gene Tree for DENND2D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DENND2D gene
    ST52  DENND5A2  DENND2A2  DENND32  DENND1C2  DENND4A2  DENND4B2  DENND1B2  
    DENND1A2  DENND5B2  DENND2C2  DENND4C2  
    4 SIMAP similar genes for DENND2D using alignment to 1 protein entry:     DEN2D_HUMAN:
    DKFZp667I053    ST5    DENND2A    DENND2C

    Find genes that share paralogs with DENND2D           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DENND2D (see all 501)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1808525301,2
    --111728264(+) CATTAA/CTTTTC 2 -- ds50010--------
    rs6413791,2
    C,F,O,A,H--111728285(+) ATTGTT/CCGAAT 2 -- ds500138Minor allele frequency- C:0.17NA EA NS WA CSA 3068
    rs1866945581,2
    --111728310(+) AATACA/GTACAG 2 -- ds50010--------
    rs1468968721,2
    --111728342(+) GTATTA/GAAAGC 2 -- ds50010--------
    rs1479512381,2
    --111728437(+) TATCTA/GTAGTG 2 -- ds50010--------
    rs1145626101,2
    C,F--111728441(+) TATAGT/GGGAAA 2 -- ds50011Minor allele frequency- G:0.01NA 120
    rs762507721,2
    C,F--111728455(+) AGGCCC/TGGAGA 2 -- ds50013Minor allele frequency- T:0.13CSA WA 121
    rs1418958671,2
    --111728462(+) GAGAGC/GTTAAA 2 -- ds50010--------
    rs1911270561,2
    --111728488(+) ACTTGC/TTATTT 2 -- ds50010--------
    rs1457594231,2
    --111728535(+) GTGCAC/GTGTTC 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for DENND2D (111729796 - 111747157 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DENND2D:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv463250CNV Loss19166990
    nsv10639CNV Gain18304495

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615111    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for DENND2D:
    Lung squamous cell carcinoma

    Find genes that share disorders with DENND2D           About GenesLikeMe

    Genetic Association Database (GAD): DENND2D

    Export disorders for DENND2D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DENND2D gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DENND2D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Suppression of non-small cell lung cancer proliferation and tumorigenicity by DENND2D. (PubMed id 23182661)1, 2 Ling B.... Zhang K. (Lung Cancer 2013)
    2. Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)1, 2 Yoshimura S.... Barr F.A. (J. Cell Biol. 2010)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (PubMed id 22001757)1 Chambers J.C....Kooner J.S. (Nat. Genet. 2011)
    9. Identification of ARHGEF17, DENND2D, FGFR3, and RB1 mutations in melanoma by inhibition of nonsense-mediated mRNA decay. (PubMed id 18677770)1 Bloethner S....Hayward N.K. (amp 2008)
    10. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79961 HGNC: 26192 AceView: FLJ22457 Ensembl:ENSG00000162777 euGenes: HUgn79961
    ECgene: DENND2D H-InvDB: DENND2D

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DENND2D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DENND2D gene:
    Search GeneIP for patents involving DENND2D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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