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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DENND2C Gene

protein-coding   GIFtS: 41
GCID: GC01M115125

DENN/MADD Domain Containing 2C

  Search for DENND2C
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DENN/MADD Domain Containing 2C1 2
dJ1156J9.12
DENN Domain-Containing Protein 2C2

External Ids:    HGNC: 247481   Entrez Gene: 1632592   Ensembl: ENSG000001759847   UniProtKB: Q68D513   

Export aliases for DENND2C gene to outside databases

Previous GC identifers: GC01M114838 GC01M112985


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DENND2C Gene: 
DENND2C (DENN/MADD domain containing 2C) is a protein-coding gene. GO annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is ST5.

UniProtKB/Swiss-Prot: DEN2C_HUMAN, Q68D51
Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of
GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DENND2C gene promoter:
         HFH-3   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   E4BP4   POU3F2   GATA-2   Evi-1   FOXI1   FAC1   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDENND2C promoter sequence
   Search SABiosciences Chromatin IP Primers for DENND2C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND2C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.2   Ensembl cytogenetic band:  1p13.2   HGNC cytogenetic band: 1p13.2-p13.1

DENND2C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DENND2C gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M115125:  view genomic region     (about GC identifiers)

Start:
115,125,469 bp from pter      End:
115,213,043 bp from pter
Size:
87,575 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DEN2C_HUMAN, Q68D51 (See protein sequence)
Recommended Name: DENN domain-containing protein 2C  
Size: 928 amino acids; 106865 Da
Secondary accessions: B1AL26 Q5TCX6 Q6P3R3
Alternative splicing: 3 isoforms:  Q68D51-1   Q68D51-2   Q68D51-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DENND2C: NX_Q68D51

Explore proteomics data for DENND2C at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q68D51

  • DENND2C Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DENND2C Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001243333.1  NP_940861.3  

    ENSEMBL proteins: 
     ENSP00000376957   ENSP00000376955   ENSP00000376958  

    Human Recombinant Protein Products for DENND2C: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DENND: DENN/MADD domain containing

    3 InterPro protein domains:
     IPR005112 dDENN_dom
     IPR005113 uDENN_dom
     IPR001194 DENN_dom

    Graphical View of Domain Structure for InterPro Entry Q68D51

    ProtoNet protein and cluster: Q68D51

    UniProtKB/Swiss-Prot: DEN2C_HUMAN, Q68D51
    Similarity: Contains 1 dDENN domain
    Similarity: Contains 1 DENN domain
    Similarity: Contains 1 uDENN domain


    DENND2C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DEN2C_HUMAN, Q68D51
    Function: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of
    GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017112Rab guanyl-nucleotide exchange factor activity IDA--
         
    DENND2C for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DENND2C 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DENND2C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DENND2C 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DENND2C 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DENND2C
    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate DENND2C (see all 17):
    hsa-miR-15a hsa-miR-938 hsa-miR-765 hsa-miR-1271 hsa-miR-488 hsa-miR-424 hsa-miR-3674 hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidDENND2C 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for DENND2C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DENND2C (NM_198459)
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                         Customized lentivirus expression plasmids for stable overexpression of DENND2C 

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND2C


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DENND2C

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DENND2C (DEN2C)

    Search CenterWatch for drugs/clinical trials and news about DENND2C / DEN2C

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DENND2C gene (2 alternative transcripts): 
    NM_001256404.1  NM_198459.3  

    Unigene Cluster for DENND2C:

    DENN/MADD domain containing 2C
    Hs.654928  [show with all ESTs]
    Unigene Representative Sequence: CR749576
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393276(uc001efc.1) ENST00000393274(uc001efd.1 uc001eez.3)
    ENST00000495031 ENST00000481894 ENST00000493549 ENST00000393277
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DENND2C
    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate DENND2C (see all 17):
    hsa-miR-15a hsa-miR-938 hsa-miR-765 hsa-miR-1271 hsa-miR-488 hsa-miR-424 hsa-miR-3674 hsa-miR-580
    SwitchGear 3'UTR luciferase reporter plasmidDENND2C 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for DENND2C
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DENND2C
    Clone
    Products:
         
    OriGene clones in human, mouse for DENND2C (see all 7)
    OriGene ORF clones in mouse, rat for DENND2C
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    GenScript: all cDNA clones in your preferred vector: DENND2C (NM_198459)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DENND2C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DENND2C
    Sirion Biotech Customized lentivirus for stable overexpression of DENND2C 
                         Customized lentivirus expression plasmids for stable overexpression of DENND2C 
    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DENND2C
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DENND2C
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND2C

    Additional mRNA sequence: 

    AK124287.1 AK308302.1 BX647950.1 BX649075.1 CR749576.1 

    8 DOTS entries:

    DT.92022915  DT.99930268  DT.100668325  DT.209625  DT.95196374  DT.121388834  DT.40126901  DT.86846717 

    24/358 AceView cDNA sequences (see all 358):

    BM725933 CB159342 AW849664 NM_000036 AA719669 BQ424395 BU155332 F32963 
    CK902410 BG429612 BU678635 W32722 AA808494 BE671544 BM805502 AI051051 
    BC056678 AF081788 BQ938544 AA626887 AW083722 AI187046 AW138855 BG030450 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DENND2C expression in normal human tissues (normalized intensities)      DENND2C embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACTGTGGTA
    DENND2C Expression
    About this image


    DENND2C expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Epidermis (Integumentary System)
             Stratified Epidermis
     
     Testis (Reproductive System)

    See DENND2C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DENND2C

    SOURCE GeneReport for Unigene cluster: Hs.654928
        SABiosciences Custom PCR Arrays for DENND2C
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DENND2C
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DENND2C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DENND2C gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dennd2c1 , 5 DENN/MADD domain containing 2C1, 5 83.82(n)1
    83.9(a)1
      3 (45.25 cM)5
    3297271  NM_177857.11  NP_808525.21 
     1031026045 
    chicken
    (Gallus gallus)
    Aves DENND2C1 DENN/MADD domain containing 2C 67.41(n)
    68.49(a)
      100858235  XM_003642727.1  XP_003642775.1 
    lizard
    (Anolis carolinensis)
    Reptilia DENND2C6
    Uncharacterized protein
    71(a)
    1 ↔ 1
    4(130279678-130312380)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkeyp-31a2.11 si:dkeyp-31a2.1 58.95(n)
    57.66(a)
      570947  XM_001919051.3  XP_001919086.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG186596
    --
    12(a)
    1 → many
    2R(5010809-5019486)
    worm
    (Caenorhabditis elegans)
    Secernentea rme-46
    Protein RME-4, isoform a
    14(a)
    1 → many
    X(10373230-10377752)


    ENSEMBL Gene Tree for DENND2C (if available)
    TreeFam Gene Tree for DENND2C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DENND2C gene
    ST52  DENND5A2  DENND2D2  DENND2A2  DENND32  DENND1C2  DENND4A2  DENND4B2  
    DENND1B2  DENND5B2  DENND1A2  DENND4C2  
    4 SIMAP similar genes for DENND2C using alignment to 2 protein entries:     DEN2C_HUMAN (see all proteins):
    DKFZp667I053    ST5    DENND2D    DENND2A

    DENND2C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1649 SNPs in DENND2C are shown (see all 1649)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1381807191,2
    --115126711(+) TGGTAC/TACTTA 2 -- ds50010--------
    rs1495637331,2
    --115126825(+) GCTTCA/TGTTCT 2 -- ds50010--------
    rs1824571081,2
    --115126852(+) GGCAAC/TGTATT 2 -- ds50010--------
    rs1432172531,2
    --115126882(+) TTTTTC/GTTTTT 2 -- ds50010--------
    rs1483356291,2
    C--115126954(+) GTGGCA/GCGATC 2 -- ds50010--------
    rs1850683741,2
    --115126995(+) TCAAGC/TGATTC 2 -- ds50010--------
    rs2224941,2
    F--115127059(-) aaaaaT/Ctagct 2 -- ds50011Minor allele frequency- C:0.00NA 2
    rs1816985631,2
    --115127080(+) TTTAGA/TAGAGA 2 -- ds50010--------
    rs1414670471,2
    C--115127251(+) TTTAAA/GGATTG 2 -- ut310--------
    rs1463729521,2
    --115127272(+) TATGCA/GTACAT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for DENND2C (115125469 - 115213043 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for DENND2C:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv2498CNV Insertion18451855
    esv28734CNV Loss19812545
    nsv831104CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DENND2C
    DNA2.0 Custom Variant and Variant Library Synthesis for DENND2C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DENND2C gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DENND2C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (2013)
    4. Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)2 Yoshimura S.... Barr F.A. (2010)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 163259 HGNC: 24748 AceView: AMPD1andBCAS2andFLJ37099 Ensembl:ENSG00000175984 euGenes: HUgn163259
    ECgene: DENND2C H-InvDB: DENND2C

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DENND2C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DENND2C gene:
    Search GeneIP for patents involving DENND2C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for DENND2C  
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DENND2C
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     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DENND2C
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DENND2C
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     Regulatory tfbs in DENND2C promoter
     Search Chromatin IP Primers for DENND2C
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     Proteins for DENND2C
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     Search LifeMap BioReagents cell lines for DENND2C
     Gene Synthesis
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     Search ThermoFisher Antibodies for DENND2C
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DENND2C
     inGenious Targeting Laboratory - Custom generated mouse model solutions for DENND2C
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DENND2C
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    Customized transgenic rodents for:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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