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Aliases for DEFT1P Gene

Aliases for DEFT1P Gene

  • Defensin, Theta 1 Pseudogene 2 3 5
  • Defensin-Related Pseudogene 3
  • Retrocyclin Pseudogene 3
  • Circular Minidefensin 3
  • Defensin, Theta 1 2
  • Pro-Retrocyclin 3
  • Demidefensin 3
  • Retrocyclin 2
  • DEFQ1 3
  • DEFT1 3

External Ids for DEFT1P Gene

Previous HGNC Symbols for DEFT1P Gene

  • DEFQ1
  • DEFT1

Previous GeneCards Identifiers for DEFT1P Gene

  • GC00U921565
  • GC08U900587
  • GC08M006823
  • GC08M006844

Summaries for DEFT1P Gene

GeneCards Summary for DEFT1P Gene

DEFT1P (Defensin, Theta 1 Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DEFT1P Gene

Genomics for DEFT1P Gene

Genomic Location for DEFT1P Gene

Chromosome:
8
Start:
6,987,178 bp from pter
End:
6,989,721 bp from pter
Size:
2,544 bases
Orientation:
Minus strand

Genomic View for DEFT1P Gene

Genes around DEFT1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DEFT1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DEFT1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DEFT1P Gene

No data available for Regulatory Elements for DEFT1P Gene

Proteins for DEFT1P Gene

Post-translational modifications for DEFT1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for DEFT1P Gene

Domains & Families for DEFT1P Gene

Suggested Antigen Peptide Sequences for DEFT1P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for DEFT1P Gene

Function for DEFT1P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DEFT1P Gene

Localization for DEFT1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DEFT1P Gene

Pathways & Interactions for DEFT1P Gene

SuperPathways for DEFT1P Gene

No Data Available

Interacting Proteins for DEFT1P Gene

Gene Ontology (GO) - Biological Process for DEFT1P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DEFT1P Gene

Transcripts for DEFT1P Gene

mRNA/cDNA for DEFT1P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for DEFT1P Gene

No ASD Table

Relevant External Links for DEFT1P Gene

GeneLoc Exon Structure for
DEFT1P
ECgene alternative splicing isoforms for
DEFT1P

Expression for DEFT1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DEFT1P Gene

mRNA differential expression in normal tissues according to GTEx for DEFT1P Gene

This gene is overexpressed in Whole Blood (x48.1).

NURSA nuclear receptor signaling pathways regulating expression of DEFT1P Gene:

DEFT1P

SOURCE GeneReport for Unigene cluster for DEFT1P Gene:

Hs.681792
genes like me logo Genes that share expression patterns with DEFT1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for DEFT1P Gene

Orthologs for DEFT1P Gene

Evolution for DEFT1P Gene

ENSEMBL:
Gene Tree for DEFT1P (if available)
TreeFam:
Gene Tree for DEFT1P (if available)

No data available for Orthologs for DEFT1P Gene

Paralogs for DEFT1P Gene

No data available for Paralogs for DEFT1P Gene

Variants for DEFT1P Gene

Sequence variations from dbSNP and Humsavar for DEFT1P Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001163 -- 6,988,263(-) ACCTT(C/T)GCCCT nc-transcript-variant
rs138305127 -- 6,989,127(+) TGACA(C/T)CAAAG intron-variant
rs139516555 -- 6,990,302(+) GCACA(C/T)AGTAT upstream-variant-2KB
rs140222441 -- 6,988,631(+) TGTTC(A/G)ATAAG intron-variant
rs141092423 -- 6,989,637(+) GAAAG(-/T)TTTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DEFT1P Gene

Variant ID Type Subtype PubMed ID
dgv11907n54 CNV loss 21841781
dgv11908n54 CNV gain 21841781
dgv11909n54 CNV loss 21841781
dgv11910n54 CNV loss 21841781
dgv2033e212 CNV loss 25503493
dgv2034e212 CNV loss 25503493
dgv3758n106 CNV deletion 24896259
dgv4043e59 CNV duplication 20981092
dgv6878n100 CNV gain 25217958
dgv6879n100 CNV gain 25217958
dgv6880n100 CNV loss 25217958
dgv6881n100 CNV gain 25217958
dgv6882n100 CNV gain 25217958
esv21544 CNV gain+loss 19812545
esv2736554 CNV deletion 23290073
esv2752262 CNV gain 17911159
esv2759589 CNV gain+loss 17122850
esv2761169 CNV gain+loss 21179565
esv2764122 CNV loss 21179565
esv3358388 CNV duplication 20981092
esv3384686 CNV duplication 20981092
esv3576520 CNV gain 25503493
nsv1015244 CNV gain 25217958
nsv1031577 CNV gain 25217958
nsv1115772 CNV duplication 24896259
nsv1141567 CNV duplication 24896259
nsv21 CNV deletion 15895083
nsv22 CNV insertion 15895083
nsv428194 CNV gain+loss 18775914
nsv435861 CNV deletion 17901297
nsv437041 CNV loss 16327808
nsv465436 CNV gain 19166990
nsv471499 CNV gain 19718026
nsv515096 CNV gain 21397061
nsv527917 CNV gain 19592680
nsv528374 CNV gain 19592680
nsv6060 CNV deletion 18451855
nsv6062 CNV insertion 18451855
nsv6064 CNV insertion 18451855
nsv610006 CNV gain 21841781
nsv610010 CNV gain 21841781
nsv610018 CNV loss 21841781
nsv610025 CNV loss 21841781
nsv610031 CNV loss 21841781
nsv820476 CNV duplication 20802225
nsv8278 CNV gain+loss 18304495
nsv831221 CNV gain 17160897
nsv950282 CNV duplication 24416366

Relevant External Links for DEFT1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DEFT1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DEFT1P Gene

Disorders for DEFT1P Gene

Relevant External Links for DEFT1P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DEFT1P

No disorders were found for DEFT1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DEFT1P Gene

Publications for DEFT1P Gene

  1. Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. (PMID: 11854483) Cole A.M. … Lehrer R.I. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 22 64
  2. Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence. (PMID: 15588320) Taudien S. … Platzer M. (BMC Genomics 2004) 2 3 64
  3. Evolution of primate theta-defensins: a serpentine path to a sweet tooth. (PMID: 15019196) Nguyen T.X. … Lehrer R.I. (Peptides 2003) 2 3 64
  4. Defensins of vertebrate animals. (PMID: 11790538) Lehrer R.I. … Ganz T. (Curr. Opin. Immunol. 2002) 3 22 64
  5. Molecular evolution of the primate I+-/I,-defensin multigene family. (PMID: 24819937) Cheng D.Q. … Huang J.F. (PLoS ONE 2014) 3 64

Products for DEFT1P Gene

Sources for DEFT1P Gene

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