Aliases for DEFB4A Gene
External Ids for DEFB4A Gene
Previous HGNC Symbols for DEFB4A Gene
Previous GeneCards Identifiers for DEFB4A Gene
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
GeneCards Summary for DEFB4A Gene
DEFB4A (Defensin, Beta 4A) is a Protein Coding gene. Diseases associated with DEFB4A include oral candidiasis and middle ear cholesteatoma. Among its related pathways are Defensins and Bacterial infections in CF airways. An important paralog of this gene is DEFB4B.
UniProtKB/Swiss-Prot for DEFB4A Gene
Has antibacterial activity.