Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



DEFB118 Gene

protein-coding   GIFtS: 50
GCID: GC20P029956

Defensin, Beta 118

(Previous name: chromosome 20 open reading frame 63)
(Previous symbol: C20orf63)
  See DEFB118-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Defensin, Beta 1181 2 3     Chromosome 20 Open Reading Frame 631
C20orf631 2 3 5     Beta-Defensin 1182
ESC422 3 5     Defensin, Beta 182
Epididymal Secretory Protein 13.62 3     Epididymus Specific Clone 422
DEFB-182 3     DEFB183
ESP13.62 3     Beta-Defensin 183

External Ids:    HGNC: 161961   Entrez Gene: 1172852   Ensembl: ENSG000001310687   OMIM: 6076505   UniProtKB: Q96PH63   

Export aliases for DEFB118 gene to outside databases

Previous GC identifers: GC20P029744 GC20P030654 GC20P030701 GC20P029420 GC20P026745


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for DEFB118 Gene:
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that
protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by
androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a
cluster with other beta-defensin genes on the long arm of chromosome 20. (provided by RefSeq, Dec 2010)

GeneCards Summary for DEFB118 Gene:
DEFB118 (defensin, beta 118) is a protein-coding gene. Diseases associated with DEFB118 include childhood leukemia.

UniProtKB/Swiss-Prot: DB118_HUMAN, Q96PH6
Function: Has antibacterial activity (Potential)

Gene Wiki entry for DEFB118 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the DEFB118 gene promoter:
         Sox5   C/EBPbeta   FOXD1   STAT5A   LCR-F1   C/EBPalpha   POU2F1   POU2F1a   HSF1short   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDEFB118 promoter sequence
   Search Chromatin IP Primers for DEFB118

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DEFB118


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21   Ensembl cytogenetic band:  20q11.21   HGNC cytogenetic band: 20q11.21

DEFB118 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEFB118 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P029956:  view genomic region     (about GC identifiers)

Start:
29,956,421 bp from pter      End:
29,961,726 bp from pter
Size:
5,306 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: DB118_HUMAN, Q96PH6 (See protein sequence)
Recommended Name: Beta-defensin 118 precursor  
Size: 123 amino acids; 13614 Da
Secondary accessions: Q17RC4 Q8N691 Q9NUH0

Explore the universe of human proteins at neXtProt for DEFB118: NX_Q96PH6

Explore proteomics data for DEFB118 at MOPED


See DEFB118 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_473453.1  
ENSEMBL proteins: 
 ENSP00000253381  
Reactome Protein details: Q96PH6

DEFB118 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for DEFB118
OriGene Protein Over-expression Lysate for DEFB118
OriGene MassSpec for DEFB118
OriGene Custom Protein Services for DEFB118
GenScript Custom Purified and Recombinant Proteins Services for DEFB118
Novus Biologicals DEFB118 Protein
Novus Biologicals DEFB118 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for DEFB118 

DEFB118 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for DEFB118
Novus Biologicals DEFB118 Antibody
Abcam antibodies for DEFB118
Browse Antibodies at Cloud-Clone Corp.
Search ThermoFisher Antibodies for DEFB118
Search LSBio for Antibodies for DEFB118

DEFB118 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for DEFB118
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for DEFB118
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.
Search eBioscience for ELISAs for DEFB118 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
DEFB: Defensins, beta

1 InterPro protein domain:
 IPR025933 Beta_defensin

Graphical View of Domain Structure for InterPro Entry Q96PH6

ProtoNet protein and cluster: Q96PH6

UniProtKB/Swiss-Prot: DB118_HUMAN, Q96PH6
Similarity: Belongs to the beta-defensin family


Find genes that share domains with DEFB118           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: DB118_HUMAN, Q96PH6
Function: Has antibacterial activity (Potential)

Phenotypes:
     1 GenomeRNAi human phenotype for DEFB118:

 Synthetic lethal with Ras 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DEFB118
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DEFB118

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DEFB118
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DEFB118

miRNA
Products:
    
miRTarBase miRNAs that target DEFB118:
hsa-mir-124-3p (MIRT022118), hsa-mir-335-5p (MIRT016750)

Block miRNA regulation of human, mouse, rat DEFB118 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate DEFB118
SwitchGear 3'UTR luciferase reporter plasmidDEFB118 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for DEFB118
Predesigned siRNA for gene silencing in human, mouse, rat DEFB118

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for DEFB118

Clone
Products:
     
OriGene clones in human, mouse for DEFB118 (see all 5)
OriGene ORF clones in mouse, rat for DEFB118
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: DEFB118 (NM_054112)
Sino Biological Human cDNA Clone for DEFB118
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DEFB118
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEFB118

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for DEFB118
Browse ESI BIO Cell Lines and PureStem Progenitors for DEFB118 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFB118


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
DB118_HUMAN, Q96PH6: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--

Find genes that share ontologies with DEFB118           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

SuperPaths for DEFB118 About    
See pathways by source

SuperPathContained pathways About
1Defensins
Defensins0.80
Beta defensins0.80


Find genes that share SuperPaths with DEFB118           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



2 Reactome Pathways for DEFB118
    Defensins
Beta defensins


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DEFB118
Interactions:

    Search GeneGlobe Interaction Network for DEFB118

Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007160cell-matrix adhesion NAS11564719
GO:0007283spermatogenesis NAS11564719
GO:0042742defense response to bacterium TAS10588992
GO:0045087innate immune response TAS10588992

Find genes that share ontologies with DEFB118           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for DEFB118 (DB118)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for DEFB118 gene: 
NM_054112.2  

Unigene Cluster for DEFB118:

Defensin, beta 118
Hs.274124  [show with all ESTs]
Unigene Representative Sequence: BC035677
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000253381(uc002wvr.3)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat DEFB118 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate DEFB118
SwitchGear 3'UTR luciferase reporter plasmidDEFB118 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for DEFB118
Predesigned siRNA for gene silencing in human, mouse, rat DEFB118
Clone
Products:
     
OriGene clones in human, mouse for DEFB118 (see all 5)
OriGene ORF clones in mouse, rat for DEFB118
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: DEFB118 (NM_054112)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for DEFB118
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEFB118
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for DEFB118
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DEFB118
  QuantiTect SYBR Green Assays in human, mouse, rat DEFB118
  QuantiFast Probe-based Assays in human, mouse, rat DEFB118

Additional mRNA sequence: 

AF347073.1 AF529415.1 AY122471.1 BC035677.1 BC117378.1 

1 DOTS entry:

DT.40266824 

3 AceView cDNA sequences:

AA835052 BM554548 BC035677 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

DEFB118 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACTTCCTCTC
DEFB118 Expression
About this image

DEFB118 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

DEFB118 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.274124

UniProtKB/Swiss-Prot: DB118_HUMAN, Q96PH6
Tissue specificity: High-level and epididymis-specific expression. Most abundant in the epithelium of the caput
and is also present in the lumen and bound to sperm. Expressed also in pancreas

    Custom PCR Arrays for DEFB118
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for DEFB118
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DEFB118
QuantiTect SYBR Green Assays in human, mouse, rat DEFB118
QuantiFast Probe-based Assays in human, mouse, rat DEFB118
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFB118

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of human and mouse.

Orthologs for DEFB118 gene from Selected species (see all 2)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Defb215 defensin beta 21   --   2 (75.31 cM) 152572744 


ENSEMBL Gene Tree for DEFB118 (if available)
TreeFam Gene Tree for DEFB118 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for DEFB118 gene
6 SIMAP similar genes for DEFB118 using alignment to 1 protein entry:     DB118_HUMAN:
DEFB117    DEFB115    DEFB123    DEFB132    DEFB121    DEFB126

Find genes that share paralogs with DEFB118           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for DEFB118 (see all 174)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1414352381,2
--29954466(+) ACCCAC/GCTAGC 1 -- us2k10--------
rs788259271,2
C,F--29954623(+) CTTTTC/TTGTAG 1 -- us2k11Minor allele frequency- T:0.02NA 120
rs1508195271,2
--29954635(+) AAGAGA/CGAAAA 1 -- us2k10--------
rs1392396951,2
--29954644(+) AAAAGA/GTGTTT 1 -- us2k10--------
rs171246711,2
C,F--29954718(+) CATTCA/GTAAAA 1 -- us2k15Minor allele frequency- G:0.03NA WA 262
rs1445262221,2
--29954805(+) AATCAC/GTTAGA 1 -- us2k10--------
rs1144806261,2
C,F--29954928(+) GGTGCA/GGTGGC 1 -- us2k11Minor allele frequency- G:0.02WA 118
rs1859679001,2
--29954954(+) CAGCAC/GTTTGG 1 -- us2k10--------
rs1466236031,2
--29955181(+) CCTGGA/GCTACA 1 -- us2k10--------
rs1401302341,2
--29955270(+) CCACAA/TGGTTC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for DEFB118 (29956421 - 29961726 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for DEFB118:    About this table    
Variant IDTypeSubtypePubMed ID
nsv458961CNV Gain19166990
nsv912835CNV Gain21882294
nsv470546CNV Gain18288195

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing DEFB118
DNA2.0 Custom Variant and Variant Library Synthesis for DEFB118

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 607650    OMIM disorders: --

1 disease for DEFB118:    
About MalaCards
childhood leukemia


Find genes that share disorders with DEFB118           About GenesLikeMe

Genetic Association Database (GAD): DEFB118
Human Genome Epidemiology (HuGE) Navigator: DEFB118 (6 documents)

Export disorders for DEFB118 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for DEFB118 gene, integrated from 10 sources (see all 13):
(articles sorted by number of sources associating them with DEFB118)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human. (PubMed id 11564719)1, 2, 3, 9 Liu Q.... Hall S.H. (Endocrinology 2001)
  2. The androgen-regulated epididymal sperm-binding protein, human beta-defensin 118 (DEFB118) (formerly ESC42), is an antimicrobial beta-defensin. (PubMed id 15033915)1, 3, 9 Yenugu S....Hall S.H. (Endocrinology 2004)
  3. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (Hum. Immunol. 2010)
  4. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (amp 2010)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. ORFeome-based search of airway epithelial cell-specific novel human beta-defensin genes. (PubMed id 12600824)1, 2 Kao C.Y.... Wu R. (Am. J. Respir. Cell Mol. Biol. 2003)
  7. Discovery of five conserved beta-defensin gene clusters using a computational search strategy. (PubMed id 11854508)1, 2 Schutte B.C.... McCray P.B. Jr. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
  9. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
  10. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (amp 2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 117285 HGNC: 16196 AceView: DEFB118 Ensembl:ENSG00000131068 euGenes: HUgn117285
ECgene: DEFB118 H-InvDB: DEFB118

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for DEFB118 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for DEFB118 gene:
Search GeneIP for patents involving DEFB118

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DEFB118  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for DEFB118  
 OriGene MassSpec something-or-other for DEFB118   OriGene clones in human, mouse for DEFB118  
 OriGene qSTAR qPCR primer pairs in human, mouse for DEFB118   OriGene Purified Protein for DEFB118  
 OriGene ORF clones in mouse, rat for DEFB118   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for DEFB118   OriGene Custom Protein Services for DEFB118  

 
 
 Block miRNA regulation of human, mouse, rat DEFB118 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing DEFB118
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DEFB118 Predesigned siRNA for gene silencing in human, mouse, rat DEFB118
 QuantiFast Probe-based Assays in human, mouse, rat DEFB118 QuantiTect SYBR Green Assays in human, mouse, rat DEFB118
 Custom PCR Arrays for DEFB118 Search Chromatin IP Primers for DEFB118
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DEFB118  Search GeneGlobe Interaction Network for DEFB118
 Regulatory tfbs in DEFB118 promoter
 GenScript Custom Purified and Recombinant Proteins Services for DEFB118 GenScript cDNA clones with any tag delivered in your preferred vector for DEFB118
 GenScript Custom Assay Services for DEFB118 GenScript Custom overexpressing Cell Line Services for DEFB118
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for DEFB118 (DB118)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 cDNA Clones for DEFB118
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 DEFB118 antibodies
 DEFB118 proteins
 DEFB118 lysates
 Antibodies for DEFB118
 See all of Abcam's Antibodies, Kits and Proteins for DEFB118
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for DEFB118
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFB118
 SwitchGear 3'UTR luciferase reporter plasmids for DEFB118
 SwitchGear Promoter luciferase reporter plasmids for DEFB118
 Search ThermoFisher Antibodies for DEFB118
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEFB118
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DEFB118
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DEFB118
 Search LSBio for Antibodies for DEFB118
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for DEFB118
  Search eBioscience for proteins for DEFB118
  Search eBioscience for elisas for DEFB118
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      DEFB118 gene at Home site.
Version: 3.12.212 17 Sep 2014
hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4