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Aliases for DEFB108C Gene

Aliases for DEFB108C Gene

  • Defensin Beta 108C 2 3 5
  • Defensin Beta 108 Pseudogene 2 2 3
  • DEFB108P2 3 4
  • Putative Beta-Defensin 108B Pseudogene 1/2 4
  • Defensin, Beta 108, Pseudogene 2 2
  • Defensin, Beta 108A 4
  • Defensin, Beta 108C 4
  • DEFB108A DEFB108C 4
  • DEFB108P1 4

External Ids for DEFB108C Gene

Previous HGNC Symbols for DEFB108C Gene

  • DEFB108P2

Summaries for DEFB108C Gene

GeneCards Summary for DEFB108C Gene

DEFB108C (Defensin Beta 108C) is a Pseudogene.

UniProtKB/Swiss-Prot for DEFB108C Gene

  • Has antibacterial activity.

Additional gene information for DEFB108C Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DEFB108C Gene

Genomics for DEFB108C Gene

Regulatory Elements for DEFB108C Gene

Enhancers for DEFB108C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H007354 0.9 ENCODE 0.4 -17.6 -17641 1.1 RB1 ZNF76 KLF17 ZNF2 RAD21 GLIS2 ZNF143 ZNF207 EGR2 ZNF202 MCPH1 FAM86B3P FAM66B DEFB108C
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DEFB108C on UCSC Golden Path with GeneCards custom track

Genomic Locations for DEFB108C Gene

Genomic Locations for DEFB108C Gene
chr8:7,373,114-7,377,500
(GRCh38/hg38)
Size:
4,387 bases
Orientation:
Plus strand
chr8:7,230,636-7,235,022
(GRCh37/hg19)

Genomic View for DEFB108C Gene

Genes around DEFB108C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DEFB108C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DEFB108C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DEFB108C Gene

Proteins for DEFB108C Gene

  • Protein details for DEFB108C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MXU0-DB108_HUMAN
    Recommended name:
    Putative beta-defensin 108A
    Protein Accession:
    A8MXU0

    Protein attributes for DEFB108C Gene

    Size:
    73 amino acids
    Molecular mass:
    8390 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DEFB108C Gene

Post-translational modifications for DEFB108C Gene

No Post-translational modifications

No data available for DME Specific Peptides for DEFB108C Gene

Domains & Families for DEFB108C Gene

Gene Families for DEFB108C Gene

Protein Domains for DEFB108C Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8MXU0

UniProtKB/Swiss-Prot:

DB108_HUMAN :
  • Belongs to the beta-defensin family.
Family:
  • Belongs to the beta-defensin family.
genes like me logo Genes that share domains with DEFB108C: view

No data available for Suggested Antigen Peptide Sequences for DEFB108C Gene

Function for DEFB108C Gene

Molecular function for DEFB108C Gene

UniProtKB/Swiss-Prot Function:
Has antibacterial activity.

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DEFB108C Gene

Localization for DEFB108C Gene

Subcellular locations from UniProtKB/Swiss-Prot for DEFB108C Gene

No data available for Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DEFB108C Gene

Pathways & Interactions for DEFB108C Gene

SuperPathways for DEFB108C Gene

No Data Available

Interacting Proteins for DEFB108C Gene

Gene Ontology (GO) - Biological Process for DEFB108C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DEFB108C Gene

Drugs & Compounds for DEFB108C Gene

No Compound Related Data Available

Transcripts for DEFB108C Gene

mRNA/cDNA for DEFB108C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DEFB108C Gene

No ASD Table

Relevant External Links for DEFB108C Gene

GeneLoc Exon Structure for
DEFB108C
ECgene alternative splicing isoforms for
DEFB108C

Expression for DEFB108C Gene

NURSA nuclear receptor signaling pathways regulating expression of DEFB108C Gene:

DEFB108C
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DEFB108C Gene

Orthologs for DEFB108C Gene

Evolution for DEFB108C Gene

ENSEMBL:
Gene Tree for DEFB108C (if available)
TreeFam:
Gene Tree for DEFB108C (if available)

No data available for Orthologs for DEFB108C Gene

Paralogs for DEFB108C Gene

No data available for Paralogs for DEFB108C Gene

Variants for DEFB108C Gene

Relevant External Links for DEFB108C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DEFB108C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DEFB108C Gene

Disorders for DEFB108C Gene

Relevant External Links for DEFB108C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DEFB108C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DEFB108C

No disorders were found for DEFB108C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DEFB108C Gene

Publications for DEFB108C Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 3 4 60
  2. Duplication and selection in the evolution of primate beta-defensin genes. (PMID: 12734011) Semple CA … Dorin JR (Genome biology 2003) 3 4 60
  3. Narrowing down the distal border of the copy number variable beta-defensin gene cluster on human 8p23. (PMID: 24552181) Taudien S … Platzer M (BMC research notes 2014) 3 60
  4. Discovery of five conserved beta -defensin gene clusters using a computational search strategy. (PMID: 11854508) Schutte BC … McCray PB (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for DEFB108C Gene

Sources for DEFB108C Gene

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