Aliases for DEFB106A Gene
External Ids for DEFB106A Gene
Previous HGNC Symbols for DEFB106A Gene
Previous GeneCards Identifiers for DEFB106A Gene
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]
GeneCards Summary for DEFB106A Gene
DEFB106A (Defensin Beta 106A) is a Protein Coding gene. Diseases associated with DEFB106A include papilloma and intestinal benign neoplasm. Among its related pathways are Immune System and Defensins. An important paralog of this gene is DEFB106B.
UniProtKB/Swiss-Prot for DEFB106A Gene
Has antibacterial activity.