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DEFB103B Gene

protein-coding   GIFtS: 48
GCID: GC08M007277

Defensin, Beta 103B

Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Defensin, Beta 103B1 2     DEFB1032 3
DEFB32 3 5     HBP32 5
HBD32 3 5     Beta-Defensin 1032
Beta-Defensin 32 3     BD33
Defensin, Beta 1032 3     DEFB-33
Defensin-Like Protein2 3     hBD-33
BD-32 3     DEFB103A5

External Ids:    HGNC: 317021   Entrez Gene: 558942   Ensembl: ENSG000001772437   OMIM: 6066115   UniProtKB: P815343   

Export aliases for DEFB103B gene to outside databases

Previous GC identifers: GC08U900480 GC08P007779 GC08M006934


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DEFB103B Gene:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family
are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum
antimicrobial activity and may play an important role in innate epithelial defense. (provided by RefSeq, Jul
2008)

GeneCards Summary for DEFB103B Gene:
DEFB103B (defensin, beta 103B) is a protein-coding gene. Diseases associated with DEFB103B include esophageal candidiasis, and middle ear cholesteatoma. An important paralog of this gene is DEFB103A.

UniProtKB/Swiss-Prot: D103A_HUMAN, P81534
Function: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative
bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant
E.faecium. No significant hemolytic activity was observed

Gene Wiki entry for DEFB103B (DEFB103A) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the DEFB103B gene promoter:
         FOXI1   C/EBPbeta   IRF-2   STAT1   p300   FOXD3   AP-4   IRF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDEFB103B promoter sequence
   Search Chromatin IP Primers for DEFB103B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DEFB103B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p23   Ensembl cytogenetic band:  8p23.1   HGNC cytogenetic band: 8p23.1

DEFB103B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEFB103B gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M007277:  view genomic region     (about GC identifiers)

Start:
7,286,410 bp from pter      End:
7,287,870 bp from pter
Size:
1,461 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: D103A_HUMAN, P81534 (See protein sequence)
Recommended Name: Beta-defensin 103 precursor  
Size: 67 amino acids; 7697 Da
Mass spectrometry: Mass=5154.59; Method=Electrospray; Range=23-67; Source=PubMed:11085990;
1 PDB 3D structure from and Proteopedia for DEFB103B:
1KJ6 (3D)    
Secondary accessions: Q8NFG6 Q9NPF6

Explore the universe of human proteins at neXtProt for DEFB103B: NX_P81534

Explore proteomics data for DEFB103B at MOPED


See DEFB103B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_061131.1  
ENSEMBL proteins: 
 ENSP00000324633  
Reactome Protein details: P81534

DEFB103B Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
DEFB: Defensins, beta

1 InterPro protein domain:
 IPR001855 Defensin_beta-typ

Graphical View of Domain Structure for InterPro Entry P81534

ProtoNet protein and cluster: P81534

1 Blocks protein domain: IPB001855 Beta defensin

UniProtKB/Swiss-Prot: D103A_HUMAN, P81534
Similarity: Belongs to the beta-defensin family


DEFB103B for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: D103A_HUMAN, P81534
Function: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative
bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant
E.faecium. No significant hemolytic activity was observed
Induction: By bacterial infection and by IFNG/IFN-gamma

Animal Models:

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
D103A_HUMAN, P81534: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
golgi apparatus4

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region ----
GO:0005796Golgi lumen ----

DEFB103B for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for DEFB103B About                                                                                                See pathways by source

SuperPathContained pathways About
1Defensins
Defensins0.80
Beta defensins0.80

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


2 Reactome Pathways for DEFB103B
    Defensins
Beta defensins



DEFB103B for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DEFB103B
Interactions:

    Search GeneGlobe Interaction Network for DEFB103B

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for DEFB103B (P815343 ENSP000003246334) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CCR6P516843, ENSP000003393934I2D: score=1 STRING: ENSP00000339393
DEFB103AENSP000003209514STRING: ENSP00000320951
About this table

Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006952defense response ----
GO:0006965positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ----
GO:0042742defense response to bacterium ----
GO:0045087innate immune response ----

DEFB103B for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for DEFB103B (D103A)

8 Novoseek inferred chemical compound relationships for DEFB103B gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
hbd2 96.8 69 18806299 (5), 18492183 (4), 12819054 (4), 19554343 (4) (see all 28)
alpha-aminobutyric acid 54.9 1 12840147 (1)
cysteine 22.7 14 18180295 (1), 16008365 (1), 19480463 (1), 19108000 (1)
anti-fungal 15.7 3 18809937 (1), 20337925 (1), 16377704 (1)
steroid 0 1 12892899 (1)
calcium 0 5 14714554 (3), 18492183 (1), 17230440 (1)
progesterone 0 1 12892899 (1)
dexamethasone 0 2 11162549 (2)



DEFB103B for compounds           About GeneDecksing



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for DEFB103B gene: 
NM_018661.3  

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000318124(uc003wrf.3)
Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA
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Search for qRT-PCR Assays for microRNAs that regulate DEFB103B
Browse SwitchGear 3'UTR luciferase reporter plasmids
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  QuantiFast Probe-based Assays in human, mouse, rat DEFB103B

8 AceView cDNA sequences:

AB037972 AF301470 AF217245 NM_018661 AF295370 AF516673 AJ237673 BQ354967 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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DEFB103B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
DEFB103B Expression
About this image

DEFB103B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

DEFB103B Protein Expression

UniProtKB/Swiss-Prot: D103A_HUMAN, P81534
Tissue specificity: Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney,
thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and
larynx. No expression in small intestine

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFB103B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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ENSEMBL Gene Tree for DEFB103B (if available)
TreeFam Gene Tree for DEFB103B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for DEFB103B gene
DEFB103A1 2  
5 SIMAP similar genes for DEFB103B using alignment to 1 protein entry:     D103A_HUMAN:
DEFB103A    DEFB4A    DEFB4B    DEFB130    DEFB130L

DEFB103B for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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7 SNPs for DEFB103B    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 8 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1999472081,2
--7287674(+) CCCACA/GCTGAG 1 -- ut510--------
rs3677998661,2
----7286122(+) GTGGAC/GAGATG 1 -- ds50010--------
rs3772831031,2
----7288355(+) AGAGGC/TCCTCC 1 -- us2k10--------
rs2012874691,2
----7286043(+) TATTTC/TTCTGA 1 -- ds50010--------
rs2020620201,2
----7287307(+) CCAGAC/TAATTT 1 -- int10--------
rs2001694361,2
----7289591(+) GGTGAA/GGACAG 1 -- us2k10--------
rs1996013171,2
----7288097(+) ATCCAG/TCCCTG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for DEFB103B (7286410 - 7287870 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for DEFB103B (see all 73):    About this table    
Variant IDTypeSubtypePubMed ID
esv2736558CNV Deletion23290073
dgv26n31CNV Duplication19718026
nsv471459CNV Duplication19718026
nsv890270CNV Loss21882294
nsv890300CNV Loss21882294
dgv7694n71CNV Loss21882294
dgv7664n71CNV Loss21882294
nsv508496CNV Loss20534489
dgv1170n67CNV Loss20364138
dgv7663n71CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 606611    OMIM disorders: --

Selected diseases for DEFB103B (see all 43):    About MalaCards
esophageal candidiasis    middle ear cholesteatoma    osteonecrosis    localized scleroderma
h. pylori infection    periodontal disease    oral candidiasis    oral squamous cell carcinoma
candidiasis    chorioamnionitis    burns    scleroderma
ulcerative colitis    cholesteatoma    atopic dermatitis    vaginitis
skin disease    cystic fibrosis    keratitis    mycosis fungoides


DEFB103B for disorders           About GeneDecksing


Congresses - knowledge worth sharing:
The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

Selected Novoseek inferred disease relationships for DEFB103B gene (see all 14)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
bacterial infections 44 4 19372483 (1), 12819054 (1), 15729370 (1)
dermatitis atopic 38.8 1 18538383 (1)
skin diseases 33.8 1 18620136 (1)
necrosis 29.3 7 11702237 (1), 15270856 (1), 12902844 (1), 11085990 (1) (see all 6)
inflammation 21.8 5 15270856 (1), 19372483 (1), 20104491 (1), 14688115 (1) (see all 5)
colitis 18.3 2 15270856 (1), 18810765 (1)
infectious disease 13.8 2 19664560 (1), 15729370 (1)
respiratory tract infections 2.11 3 16452577 (1), 17184289 (1), 19650994 (1)
colitis ulcerative 2.08 3 15270856 (2), 17387677 (1)
inflammatory bowel diseases 0 1 15270856 (1)

Human Genome Epidemiology (HuGE) Navigator: DEFB103B (0 documents)

Export disorders for DEFB103B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for DEFB103B gene, integrated from 10 sources (see all 213):
(articles sorted by number of sources associating them with DEFB103B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. (PubMed id 11085990)1, 2, 9 Harder J.... Schroeder J.-M. (J. Biol. Chem. 2001)
  2. The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus. (PubMed id 11741980)1, 2, 9 Schibli D.J.... Vogel H.J. (J. Biol. Chem. 2002)
  3. Identification of a novel, multifunctional beta-defensin (human beta- defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction. (PubMed id 11702237)1, 2, 9 Conejo-Garcia J.-R.... Bals R. (Cell Tissue Res. 2001)
  4. Discovery of new human beta-defensins using a genomics-based approach. (PubMed id 11223260)1, 2, 9 Jia H.P....McCray P.B. Jr. (Gene 2001)
  5. Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3. (PubMed id 18925411)1, 9 Varoga D....Pufe T. (Histochem. Cell Biol. 2009)
  6. Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors. (PubMed id 15934078)1, 9 Varoga D....Paulsen F. (Arthritis Rheum. 2005)
  7. Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes. (PubMed id 16954397)1, 9 Menzies B.E. and Kenoyer A. (Infect. Immun. 2006)
  8. Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. (PubMed id 20104491)1, 9 Semple F....Dorin J.R. (Eur. J. Immunol. 2010)
  9. Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci. (PubMed id 20385753)1, 9 Sass V....Sahl H.G. (Infect. Immun. 2010)
  10. Expression profile of human beta-defensin 3 in oral squamous cell carcinoma. (PubMed id 19219676)1, 9 Kesting M.R....Steinstraesser L. (Cancer Invest. 2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55894 HGNC: 31702 AceView: DEFB103A Ensembl:ENSG00000177243 euGenes: HUgn55894
ECgene: DEFB103B H-InvDB: DEFB103B

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for DEFB103B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for DEFB103B gene:
Search GeneIP for patents involving DEFB103B

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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore Mono- and Polyclonal Antibodies for the study of DEFB103B
 Browse Kits and Assays available from EMD Millipore
 EMD Millipore Purified and/or Recombinant DEFB103B Protein
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DEFB103B  
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 OriGene Custom Antibody Services for DEFB103B   OriGene Custom Protein Services for DEFB103B  

 
 
 Block miRNA regulation of human, mouse, rat DEFB103B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing DEFB103B
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DEFB103B Predesigned siRNA for gene silencing in human, mouse, rat DEFB103B
 QuantiFast Probe-based Assays in human, mouse, rat DEFB103B QuantiTect SYBR Green Assays in human, mouse, rat DEFB103B
 Custom PCR Arrays for DEFB103B Search Chromatin IP Primers for DEFB103B
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DEFB103B  Search GeneGlobe Interaction Network for DEFB103B
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 GenScript Custom Purified and Recombinant Proteins Services for DEFB103B GenScript cDNA clones with any tag delivered in your preferred vector for DEFB103B
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 Search Tocris compounds for DEFB103B (D103A)
 Browse Sino Biological Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 DEFB103B antibodies
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 Search for Antibodies for DEFB103B at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for DEFB103B
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for DEFB103B
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 Browse ESI BIO Cell Lines and PureStem Progenitors for DEFB103B
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFB103B
 Browse SwitchGear 3'UTR luciferase reporter plasmids for DEFB103B
 SwitchGear Promoter luciferase reporter plasmids for DEFB103B
 ThermoFisher Antibodies for DEFB103B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DEFB103B
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DEFB103B
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DEFB103B
 LSBio Antibodies in human, mouse, rat for DEFB103B
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
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 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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