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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DEFA6 Gene

protein-coding GIFtS: 54
GCID: GC08M006769

Defensin, Alpha 6, Paneth Cell-Specific

Microbiology & Infectious Diseases Congress

16 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Defensin, Alpha 6, Paneth Cell-Specific¹ ²
DEF6² ³ ⁵
HD-6²
Defensin 6²
defensin-6²
Defensin, Alpha 6³

External Ids:	HGNC: 2765¹	Entrez Gene: 1671²	Ensembl: ENSG00000164822⁷	OMIM: 600471⁵	UniProtKB: Q01524³

Export aliases for DEFA6 gene to outside databases

Previous GC identifers: GC08M006846 GC08M007036 GC08M006942 GC08M006562

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DEFA6 Gene:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant

in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine,

respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence

and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8.

The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of

the small intestine, and likely plays a role in host defense of human bowel. (provided by RefSeq, Jul 2008)

GeneCards Summary for DEFA6 Gene:

DEFA6 (defensin, alpha 6, Paneth cell-specific) is a protein-coding gene. Diseases associated with DEFA6 include dacryocystitis, and ulcerative colitis, and among its related super-pathways are Immune System and Beta defensins. An important paralog of this gene is DEFA1B.

UniProtKB/Swiss-Prot: DEF6_HUMAN, Q01524

Function: Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells

against infection with HIV-1

Gene Wiki entry for DEFA6 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.2 NT_023736.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DEFA6 gene promoter:
TBP AREB6 Nkx2-5 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 C/EBPalpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DEFA6 promoter sequence

Search SABiosciences Chromatin IP Primers for DEFA6

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEFA6

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p23.1 Ensembl cytogenetic band: 8p23.1 HGNC cytogenetic band: 8p23.1

DEFA6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEFA6 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M006769: view genomic region (about GC identifiers)

Start:	6,782,215 bp from pter	End:	6,783,598 bp from pter
Size:	1,384 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DEF6_HUMAN, Q01524 (See protein sequence)

Recommended Name: Defensin-6 precursor

Size: 100 amino acids; 10975 Da

Subunit: Homodimer

Subcellular location: Secreted

2 PDB 3D structures from and Proteopedia for DEFA6:

1ZMQ (3D)

3QTE (3D)

Explore the universe of human proteins at neXtProt for DEFA6: NX_Q01524

Explore proteomics data for DEFA6 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q01524

DEFA6 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_001917.1

ENSEMBL proteins:

ENSP00000297436

Reactome Protein details: Q01524
Human Recombinant Protein Products for DEFA6:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005615	extracellular space	IEA	--
GO:0005796	Golgi lumen	TAS	--

DEFA6 for ontologies About GeneDecksing

DEFA6 Antibody Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

DEFA: Defensins, alpha

4 InterPro protein domains:

IPR016327 Alpha-defensin

IPR006080 Defensin_beta/neutrophil

IPR006081 Mammalian_defensins

IPR002366 Defensin_propep

Graphical View of Domain Structure for InterPro Entry Q01524

ProtoNet protein and cluster: Q01524

1 Blocks protein domain: IPB002366 Defensin propeptide

UniProtKB/Swiss-Prot: DEF6_HUMAN, Q01524

Similarity: Belongs to the alpha-defensin family

DEFA6 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: DEF6_HUMAN, Q01524

Function: Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells

against infection with HIV-1

Genatlas biochemistry entry for DEFA6:

defensin alpha 6,3-4kDa,enteric Paneth cells,released from azurophil granules of Paneth cells,oxygen independent

phagocytosis of Gram+,Gram- bacteria,many fungi,some viruses

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for DEFA6

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DEFA6

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFA6

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for DEFA6 About

See pathways by source

SuperPath

Contained pathways About

Immune System

Immune System

0.56

Innate Immune System

0.50

Beta defensins

Defensins

0.80

Alpha-defensins

Alpha-defensins

Pathways by source See SuperPaths
Show all pathways

4 Reactome Pathways for DEFA6

	Defensins
	Alpha-defensins
	Immune System
	Innate Immune System

DEFA6 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DEFA6

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for DEFA6 (ENSP00000297436⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DEFA4	ENSP00000297435⁴	STRING: ENSP00000297435
DEFA5	ENSP00000329890⁴	STRING: ENSP00000329890
DEFB1	ENSP00000297439⁴	STRING: ENSP00000297439
DEFB4A	ENSP00000303532⁴	STRING: ENSP00000303532

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006952	defense response	--	--
GO:0031640	killing of cells of other organism	IEA	--
GO:0042742	defense response to bacterium	IEA	--
GO:0045087	innate immune response	TAS	--
GO:0050832	defense response to fungus	IEA	--

DEFA6 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

DEFA6 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DEFA6 (DEF6)

1 Novoseek inferred chemical compound relationship for DEFA6 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
hbd2	91.8	4	14568394 (2), 19549264 (1), 10964161 (1)

Search CenterWatch for drugs/clinical trials and news about DEFA6 / DEF6

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DEFA6 gene:

NM_001926.3

Unigene Cluster for DEFA6:

Defensin, alpha 6, Paneth cell-specific

Hs.711 [show with all ESTs]

Unigene Representative Sequence: NM_001926

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000297436(uc003wqt.3)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DEFA6
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for DEFA6
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DEFA6
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DEFA6

Additional mRNA sequence:

BC069667.1 BC069710.1 BC069728.1 BC069769.1 BC093951.1 BC093953.1 M98331.1

2 DOTS entries:

DT.102820200 DT.106012

10 AceView cDNA sequences:

T29657 BC069769 BC069710 BC069728 BC069667 NM_001926 BM986901 M98331

BM855691 AW951409

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DEFA6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GGTATTAACC

About this image

See DEFA6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DEFA6

SOURCE GeneReport for Unigene cluster: Hs.711

UniProtKB/Swiss-Prot: DEF6_HUMAN, Q01524

Tissue specificity: Paneth cells of the small intestine

SABiosciences Custom PCR Arrays for DEFA6

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEFA6

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for DEFA6 (if available)
TreeFam Gene Tree for DEFA6 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DEFA6 gene

DEFA1B² DEFA3² DEFA4² DEFA1² DEFA5²

6 SIMAP similar genes for DEFA6 using alignment to 2 protein entries: DEF6_HUMAN (see all proteins):

DEFA4 DEFA5 DEFA1 DEFA1B DEFA3 Em

DEFA6 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for DEFA6
PGOHUM00000249207

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs193066999^1,2		--	6781757(+)	`ACGTGC/TGGTGG`	1	--	ds500¹		0	--	--	--	--
rs184633502^1,2		--	6781758(+)	`CGTGCA/GGTGGC`	1	--	ds500¹		0	--	--	--	--
rs189149233^1,2		--	6781827(+)	`GAGTTC/TGAGAC`	1	--	ds500¹		0	--	--	--	--
rs181377813^1,2		--	6781899(+)	`TGGTGC/GATACC`	1	--	ds500¹		0	--	--	--	--
rs185543347^1,2		--	6781937(+)	`GGCAGA/GAGAAT`	1	--	ds500¹		0	--	--	--	--
rs3888152^1,2	C,F,A,H	--	6781962(+)	`AGGTAA/GAGGTT`	1	--	ds500¹		6		NA WA	18
rs146000057^1,2		--	6782201(+)	`GAAAAC/GCACAA`	1	--	ds500¹		0	--	--	--	--
rs116236599^1,2	C,F	--	6782204(+)	`AAGCAC/GAAACA`	1	--	ds500¹		0	--	--	--	--
rs712276^1,2	C,F,O,A,H	--	6782271(-)	`TGTCCT/CATACA`	1	--	ut3¹ ese³		38		MN NS EA NA CSA WA	4124
rs56239909^1,2	C,F	--	6782279(-)	`CTGTCG/ATGTGT`	1	--	ut3¹		3		CSA WA	122

HapMap Linkage Disequilibrium report for DEFA6 (6782215 - 6783598 bp)

Structural Variations
Database of Genomic Variants (DGV) 10/14 variations for DEFA6 (see all 14): About this table

Variant ID	Type	Subtype	PubMed ID
nsv509248	CNV	Insertion	20534489
nsv890064	CNV	Gain	21882294
nsv465436	CNV	Gain	19166990
nsv831221	CNV	Gain	17160897
nsv528374	CNV	Gain	19592680
esv2752262	CNV	Gain	17911159
nsv890066	CNV	Gain	21882294
nsv465437	CNV	Gain	19166990
dgv7656n71	CNV	Gain	21882294
dgv7657n71	CNV	Gain	21882294

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DEFA6

DNA2.0 Custom Variant and Variant Library Synthesis for DEFA6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DEFA6 for disorders           About GeneDecksing

OMIM gene information: 600471    OMIM disorders: --

16 diseases for DEFA6:    About MalaCards

dacryocystitis ulcerative colitis diarrhea atopic dermatitis

crohn's disease colon adenocarcinoma herpes simplex meningioma

dermatitis influenza hepatitis b adenocarcinoma

adenoma hepatitis gastric cancer leukemia

1 disease from the University of Copenhagen DISEASES database for DEFA6:

Crohn's disease

1 Novoseek inferred disease relationship for DEFA6 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
inflammation	21.5	4	15479689 (1), 12519391 (1), 19549264 (1), 18810765 (1)

Genetic Association Database (GAD): DEFA6
Human Genome Epidemiology (HuGE) Navigator: DEFA6 (8 documents)

Export disorders for DEFA6 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DEFA6 gene, integrated from 9 sources (see all 54):
(articles sorted by number of sources associating them with DEFA6)

Utopia: connect your pdf to the dynamic
world of online information

Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel. (PubMed id 8417977)^{1, 2, 3, 9} Jones D.E. and Bevins C.L. (1993)
Human enteric defensins. Gene structure and developmental expression. (PubMed id 8626737)^{1, 2, 9} Mallow E.B.... Bevins C.L. (1996)
Crystal structures of human alpha-defensins HNP4, HD5, and HD6. (PubMed id 17088326)^{1, 2, 9} Szyk A....Lubkowski J. (2006)
Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)^{1, 4} Rajaraman P....Inskip P.D. (2010)
Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)^{1, 4} Han S....Kang D. (2010)
Copy number variation of defensin genes and HIV infection in Brazilian children. (PubMed id 19194307)^{1, 4} Milanese M....Crovella S. (2009)
Single nucleotide polymorphisms and the haplotype in the DEFB1 gene are associated with atopic dermatitis in a Korean population. (PubMed id 19135873)^{1, 4} Kim E....Yang J.M. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Innate immunity and non-Hodgkin's lymphoma (NHL) relat ed genes in a nested case-control study for gastric cancer risk. (PubMed id 23028900)¹ Park S.K....Kang D. (2012)
Human a-defensin 6 promotes mucosal innate immunity th rough self-assembled peptide nanonets. (PubMed id 22722251)¹ Chu H....Bevins C.L. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 1671	HGNC: 2765	AceView: DEFA6	Ensembl:ENSG00000164822	euGenes: HUgn1671
ECgene: DEFA6	H-InvDB: DEFA6

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DEFA6	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DEFA6 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for DEFA6 gene:
Search GeneIP for patents involving DEFA6

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013

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Defensin, Alpha 6, Paneth Cell-Specific

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DEFA6 Gene

Defensin, Alpha 6, Paneth Cell-Specific

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