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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DEDD2 Gene

protein-coding   GIFtS: 47
GCID: GC19M042702

Death Effector Domain Containing 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Death Effector Domain Containing 21 2
DED-Containing Protein FLAME-32 3
FADD-Like Anti-Apoptotic Molecule 32 3
FLAME-32
DNA-Binding Death Effector Domain-Containing Protein 22
FLAME33

External Ids:    HGNC: 244501   Entrez Gene: 1629892   Ensembl: ENSG000001605707   UniProtKB: Q8WXF83   

Export aliases for DEDD2 gene to outside databases

Previous GC identifers: GC19M043343 GC19M043094 GC19M047378 GC19M047394 GC19M039134


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DEDD2 Gene:
This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may
regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis.
Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jul 2012)

GeneCards Summary for DEDD2 Gene: 
DEDD2 (death effector domain containing 2) is a protein-coding gene. Diseases associated with DEDD2 include burkitt's lymphoma, and cervicitis. GO annotations related to this gene include receptor signaling complex scaffold activity and DNA binding. An important paralog of this gene is DEDD.

UniProtKB/Swiss-Prot: DEDD2_HUMAN, Q8WXF8
Function: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the
nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general
transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DEDD2 gene promoter:
         GR   C/EBPbeta   Tal-1   CUTL1   E47   Arnt   HOXA5   c-Myb   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DEDD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DEDD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEDD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.31

DEDD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEDD2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M042702:  view genomic region     (about GC identifiers)

Start:
42,702,750 bp from pter      End:
42,724,292 bp from pter
Size:
21,543 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DEDD2_HUMAN, Q8WXF8 (See protein sequence)
Recommended Name: DNA-binding death effector domain-containing protein 2  
Size: 326 amino acids; 36179 Da
Subunit: Interacts with CASP8, CASP10 and GTF3C3. Homodimerizes and heterodimerizes with DEDD
Subcellular location: Nucleus, nucleolus. Note=Nuclear, accumulated in subnuclear structures resembling nucleoli
Sequence caution: Sequence=AAH13372.2; Type=Frameshift; Positions=186;
Secondary accessions: Q8NBR2 Q8NES1 Q8TAA8 Q96D35
Alternative splicing: 2 isoforms:  Q8WXF8-1   Q8WXF8-2   

Explore the universe of human proteins at neXtProt for DEDD2: NX_Q8WXF8

Explore proteomics data for DEDD2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXF8

  • DEDD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DEDD2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001257543.1  NP_001257544.1  NP_579874.1  

    ENSEMBL proteins: 
     ENSP00000336972   ENSP00000470082   ENSP00000471512   ENSP00000469233   ENSP00000469898  

    Human Recombinant Protein Products for DEDD2: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DEDD2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    DEDD2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011029 DEATH-like_dom
     IPR001875 DED

    Graphical View of Domain Structure for InterPro Entry Q8WXF8

    ProtoNet protein and cluster: Q8WXF8

    1 Blocks protein domain: IPB001875 Death effector protein

    UniProtKB/Swiss-Prot: DEDD2_HUMAN, Q8WXF8
    Domain: Interactions with CASP8 and CASP10 are mediated by the DED domain
    Similarity: Contains 1 DED (death effector) domain


    DEDD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DEDD2_HUMAN, Q8WXF8
    Function: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the
    nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general
    transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI11741985
    GO:0030159receptor signaling complex scaffold activity NAS11741985
         
    DEDD2 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidDEDD2 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEDD2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DEDD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/11 Interacting proteins for DEDD2 (Q8WXF83 ENSP000003369724) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASP10Q928513, ENSP000002861864I2D: score=3 STRING: ENSP00000286186
    CASP8Q147903, ENSP000003512734I2D: score=3 STRING: ENSP00000351273
    DEDDO756183, ENSP000003569854I2D: score=3 STRING: ENSP00000356985
    RHOXF2Q9BQY43, ENSP000003604414I2D: score=1 STRING: ENSP00000360441
    CFLARO155193, ENSP000003124554I2D: score=2 STRING: ENSP00000312455
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006396RNA processing NAS11741985
    GO:0008625extrinsic apoptotic signaling pathway via death domain receptors IMP11741985
    GO:0016075rRNA catabolic process NAS11741985
    GO:0019725cellular homeostasis NAS11741985

    DEDD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DEDD2

    Search CenterWatch for drugs/clinical trials and news about DEDD2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DEDD2 gene (3 alternative transcripts): 
    NM_001270614.1  NM_001270615.1  NM_133328.3  

    Unigene Cluster for DEDD2:

    Death effector domain containing 2
    Hs.515432  [show with all ESTs]
    Unigene Representative Sequence: NM_133328
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336034(uc002osu.1 uc002osv.1 uc002osw.1 uc010eid.3)
    ENST00000595337 ENST00000593804 ENST00000596251 ENST00000601135 ENST00000598415
    ENST00000602075 ENST00000600559 ENST00000598090 ENST00000598727 ENST00000593561
    ENST00000602201 ENST00000598200
    miRNA
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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate DEDD2 (see all 20):
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    SwitchGear 3'UTR luciferase reporter plasmidDEDD2 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DEDD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DEDD2

    Additional mRNA sequence: 

    AF443591.1 AF457575.1 AK075328.1 AK130203.1 AK307895.1 AY125488.1 BC013372.2 BC027930.1 
    NR_073046.1 NR_073047.1 NR_073048.1 NR_073049.1 NR_073050.1 NR_073051.1 NR_073052.1 

    11 DOTS entries:

    DT.101972579  DT.100817959  DT.454872  DT.92426460  DT.100817965  DT.86847429  DT.95304009  DT.100691056 
    DT.95290001  DT.95304007  DT.95304008 

    24/167 AceView cDNA sequences (see all 167):

    BM670485 AK130203 AF443591 BG284887 BM908148 F35595 BE907425 CD366811 
    CR590827 BI910416 CR599685 BQ956773 AI358311 BU682972 CA306521 CR593642 
    CB153442 BQ072022 BM928759 CR619301 BI907024 AW270125 BG681575 BU191631 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for DEDD2 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f
    SP1:                                            -     -     -                       -                       -                                       
    SP2:                                            -                             -                                                                     
    SP3:                                            -                             -     -                 -     -                                       
    SP4:                                            -     -     -                 -     -                       -                                       
    SP5:                                            -                             -                                                                     


    ECgene alternative splicing isoforms for DEDD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DEDD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGCCAAAAC
    DEDD2 Expression
    About this image


    See DEDD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DEDD2

    SOURCE GeneReport for Unigene cluster: Hs.515432

    UniProtKB/Swiss-Prot: DEDD2_HUMAN, Q8WXF8
    Tissue specificity: Expressed in most tissues. High levels were found in liver, kidney, heart, ovary, spleen,
    testes, skeletal muscle and peripheral blood leukocytes. Expression was absent or low in colon and small
    intestine. Expression is relatively high in the tumor cell lines chronic myologenous leukemia K-562 and the
    colorectal adenocarcinoma SW480. Expression is moderate in the cervical carcinoma HeLa, the Burkitt's lymphoma
    Raji, the lung carcinoma A-549, and the melanoma G-361. In contrast, two leukemia cell lines, HL-60
    (promyelocytic leukemia) and MOLT-4 (lymphoblastic leukemia), show relatively low levels

        SABiosciences Expression via Pathway-Focused PCR Array including DEDD2: 
              Apoptosis 384HT in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEDD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DEDD2 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dedd21 , 5 death effector domain-containing DNA binding protein more1, 5 87.73(n)1
    93.25(a)1
      7 (13.73 cM)5
    673791  NM_207677.31  NP_997560.31 
     252028405 
    lizard
    (Anolis carolinensis)
    Reptilia DEDD26
    death effector domain containing 2
    40(a)
    1 ↔ 1
    GL343909.1(20342-24100)
    zebrafish
    (Danio rerio)
    Actinopterygii dedd12 death effector domain-conatining 1 72.9(n)   58125  AF232226.1 


    ENSEMBL Gene Tree for DEDD2 (if available)
    TreeFam Gene Tree for DEDD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DEDD2 gene
    DEDD2  
    1 SIMAP similar gene for DEDD2 using alignment to 3 protein entries:     DEDD2_HUMAN (see all proteins):
    DEDD

    DEDD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/365 SNPs in DEDD2 are shown (see all 365)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1401978661,2
    C--42702271(+) GCAGTC/GAGCTG 10 -- ds50010--------
    rs1429553071,2
    --42702396(+) AACATA/GGTTGG 10 -- ds50010--------
    rs1511146011,2
    --42702418(+) ACTCCA/GAGGCA 10 -- ds50010--------
    rs1399714801,2
    C--42702482(+) CAAGCA/GTGTGG 10 -- ds50010--------
    rs774732451,2
    C,F--42702522(+) GCCCAC/TACTCC 10 -- ds50011Minor allele frequency- T:0.30EA 120
    rs1887424141,2
    --42702670(+) GCTGGC/GCTGGG 10 -- ds50010--------
    rs1922406091,2
    C--42702683(+) ACATAG/TCAAGA 10 -- ds50010--------
    rs31771461,2
    C--42702751(-) GTGGGC/AATCGG 10 -- ut31 nc-transcript-variant2Minor allele frequency- A:0.00NA 4
    rs1399086131,2
    C--42702814(+) CATCAA/CCCCCA 10 -- ut31 nc-transcript-variant0--------
    rs10442321,2
    H--42702843(-) ACCTTC/TTTGGA 10 -- ut31 nc-transcript-variant7Minor allele frequency- T:0.01MN NS EA NA 606

    HapMap Linkage Disequilibrium report for DEDD2 (42702750 - 42724292 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for DEDD2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2670755CNV Deletion23128226
    nsv520239CNV Loss19592680
    nsv911782CNV Loss21882294
    nsv833833CNV Loss17160897
    nsv522854CNV Gain19592680
    nsv526186CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    6 diseases for DEDD2:    About MalaCards
    burkitt's lymphoma    cervicitis    lymphoblastic leukemia    melanoma
    adenocarcinoma    leukemia


    DEDD2 for disorders           About GeneDecksing


    Export disorders for DEDD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DEDD2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with DEDD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC. (PubMed id 11965497)1, 2, 3, 9 Zhan Y....Alnemri E.S. (2002)
    2. DEDD regulates degradation of intermediate filaments during apoptosis. (PubMed id 12235123)1, 2, 3, 9 Lee J.C....Peter M.E. (2002)
    3. Identification and characterization of DEDD2, a death effector domain-containing protein. (PubMed id 11741985)1, 2, 9 Roth W.... Reed J.C. (2002)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. (PubMed id 12527898)1, 2 Alcivar A.... Yang X. (2003)
    7. A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. (PubMed id 22094256)1 Anders L....Sicinski P. (2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    9. Death effector domain-containing proteins. (PubMed id 18989622)1 Valmiki M.G. and Ramos J.W. (2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 162989 HGNC: 24450 AceView: DEDD2 Ensembl:ENSG00000160570 euGenes: HUgn162989
    ECgene: DEDD2 H-InvDB: DEDD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DEDD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DEDD2 gene:
    Search GeneIP for patents involving DEDD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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