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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DEDD Gene

protein-coding   GIFtS: 52
GCID: GC01M161090

Death Effector Domain Containing

(Previous name: death effector domain-containing)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Death Effector Domain Containing1 2     CASP8IP12
DEFT2 3 5     DEDD12
Death Effector Domain-Containing Testicular Molecule2 3     FLDED12
DEDPro12 3     Death Effector Domain-Containing Protein2
FLDED-12 3     DEDPRO13
Death Effector Domain-Containing1     

External Ids:    HGNC: 27551   Entrez Gene: 91912   Ensembl: ENSG000001587967   OMIM: 6068415   UniProtKB: O756183   

Export aliases for DEDD gene to outside databases

Previous GC identifers: GC01M158802 GC01M156823 GC01M157868 GC01M158308 GC01M158309 GC01M157903 GC01M159357 GC01M132448


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DEDD Gene:
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction
domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this
gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm
to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the
nucleolus. At least three transcript variants encoding the same protein have been found for this gene. (provided
by RefSeq, Jul 2008)

GeneCards Summary for DEDD Gene: 
DEDD (death effector domain containing) is a protein-coding gene. Diseases associated with DEDD include dental fluorosis, and dental caries. GO annotations related to this gene include protein binding and DNA binding. An important paralog of this gene is DEDD2.

UniProtKB/Swiss-Prot: DEDD_HUMAN, O75618
Function: A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation
during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of
intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus
and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By
similarity)

Gene Wiki entry for DEDD Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DEDD gene promoter:
         CREB   p53   deltaCREB   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDEDD promoter sequence
   Search SABiosciences Chromatin IP Primers for DEDD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DEDD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.1

DEDD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DEDD gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M161090:  view genomic region     (about GC identifiers)

Start:
161,090,764 bp from pter      End:
161,102,478 bp from pter
Size:
11,715 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DEDD_HUMAN, O75618 (See protein sequence)
Recommended Name: Death effector domain-containing protein  
Size: 318 amino acids; 36794 Da
Subunit: Interacts with CASP8, CASP10, KRT8, KRT18, CASP3 and FADD. Homodimerizes and heterodimerizes with DEDD2
Subcellular location: Cytoplasm. Nucleus, nucleolus (By similarity). Note=Translocated to the nucleus during
CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the
mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18
intermediate filament network in simple epithelial cells
Secondary accessions: D3DVF5 O60737
Alternative splicing: 2 isoforms:  O75618-1   O75618-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DEDD: NX_O75618

Explore proteomics data for DEDD at MOPED 

Post-translational modifications:

  • UniProtKB: Exists predominantly in a mono- or diubiquitinated form
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75618

  • DEDD Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DEDD Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001034800.1  NP_001034801.1  NP_127491.1  

    ENSEMBL proteins: 
     ENSP00000356985   ENSP00000356984   ENSP00000376027   ENSP00000445835   ENSP00000414821  

    Human Recombinant Protein Products for DEDD: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for DEDD 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus ISS--
    GO:0005737cytoplasm ISS--

    DEDD for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011029 DEATH-like_dom
     IPR001875 DED

    Graphical View of Domain Structure for InterPro Entry O75618

    ProtoNet protein and cluster: O75618

    1 Blocks protein domain: IPB001875 Death effector protein

    UniProtKB/Swiss-Prot: DEDD_HUMAN, O75618
    Similarity: Contains 1 DED (death effector) domain


    DEDD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DEDD_HUMAN, O75618
    Function: A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation
    during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of
    intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus
    and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ISS--
    GO:0005515protein binding IPI15688372
         
    DEDD for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DEDD:
     Increased gamma-H2AX phosphory 

         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dedd):
     cardiovascular system  endocrine/exocrine gland  growth/size  hematopoietic system  immune system 
     liver/biliary system  nervous system  renal/urinary system  reproductive system  respiratory system 

    DEDD for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Deddtm1Tmiy for DEDD

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    SwitchGear 3'UTR luciferase reporter plasmidDEDD 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DEDD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/34 Interacting proteins for DEDD (O756181, 2, 3 ENSP000003569854) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD3P840222, 3, ENSP000003329734MINT-7895480 I2D: score=1 STRING: ENSP00000332973
    APLP2Q064811, 3EBI-1043164,EBI-79306 I2D: score=1 
    CASP8Q147903, ENSP000003512734I2D: score=3 STRING: ENSP00000351273
    DEDD2Q8WXF83, ENSP000003369724I2D: score=3 STRING: ENSP00000336972
    CASP10Q928513, ENSP000002861864I2D: score=2 STRING: ENSP00000286186
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0007283spermatogenesis IEA--
    GO:0008625extrinsic apoptotic signaling pathway via death domain receptors TAS9774341
    GO:0042177negative regulation of protein catabolic process IEA--
    GO:0042981regulation of apoptotic process IEA--

    DEDD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DEDD

    Search CenterWatch for drugs/clinical trials and news about DEDD

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for DEDD gene (4 alternative transcripts): 
    NM_001039711.1  NM_001039712.1  NM_032998.2  NM_004216.2  

    Unigene Cluster for DEDD:

    Death effector domain containing
    Hs.744092  [show with all ESTs]
    Unigene Representative Sequence: NM_032998
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000472996 ENST00000368006 ENST00000489249 ENST00000486041 ENST00000368005
    ENST00000464113 ENST00000473679 ENST00000490843 ENST00000463227 ENST00000496632
    ENST00000392188(uc009wty.3 uc001fya.3 uc010pkb.2) ENST00000545495(uc001fyb.3)
    ENST00000458050(uc001fxz.3)
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    Additional mRNA sequence: 

    AF043733.1 AF064605.3 AF083236.1 AF100341.1 AJ010973.1 AK001497.1 AK022531.1 AK296629.1 
    BC013910.2 BC016724.1 CR536556.1 

    21 DOTS entries:

    DT.100878742  DT.449341  DT.100878721  DT.100878736  DT.92449686  DT.95171244  DT.100878730  DT.100878722 
    DT.100878733  DT.100878720  DT.91810806  DT.100878725  DT.95350460  DT.121398695  DT.91869741  DT.91941342 
    DT.100038736  DT.100878746  DT.121398575  DT.121398673  DT.95171160 

    24/277 AceView cDNA sequences (see all 277):

    AI805211 AF064605 CR612611 BQ962098 CR597847 AW275837 CR536556 H95383 
    T63500 AF083236 BF196668 AF043733 BU194660 AI382701 AL542105 AA829373 
    BU624713 BF437002 CR619646 BQ423248 NM_032998 AW043863 BF195222 AI092128 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DEDD (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g
    SP1:                          -                 -                                                                                       
    SP2:                                                                                      -                                             
    SP3:                                            -                                         -                                             
    SP4:                                                                                      -                                             
    SP5:                                                              -     -                 -                                             


    ECgene alternative splicing isoforms for DEDD

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DEDD expression in normal human tissues (normalized intensities)      DEDD embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCAAGTGAA
    DEDD Expression
    About this image


    DEDD expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Primary Oocyte Primary Follicle
             oocyte   
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Skeletal Muscle (Muscoskeletal System)
             gastrocnemius muscle   
     
     Eye (Sensory Organs)
             Retina
     
     Testis (Reproductive System)

    See DEDD Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DEDD

    SOURCE GeneReport for Unigene cluster: Hs.744092

    UniProtKB/Swiss-Prot: DEDD_HUMAN, O75618
    Tissue specificity: Widely expressed with highest levels in testis

        SABiosciences Expression via Pathway-Focused PCR Array including DEDD: 
              Apoptosis 384HT in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DEDD gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dedd1 , 5 death effector domain-containing1, 5 93.71(n)1
    98.74(a)1
      1 (79.34 cM)5
    219451  NM_001128609.11  NP_001122081.11 
     1713291455 
    chicken
    (Gallus gallus)
    Aves DEDD1 death effector domain containing 80.61(n)
    88.68(a)
      425378  XM_423146.3  XP_423146.1 
    lizard
    (Anolis carolinensis)
    Reptilia DEDD6
    Uncharacterized protein
    86(a)
    1 ↔ 1
    GL344298.1(6465-24954)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.84192 Xenopus laevis transcribed sequence with moderate similarity more 75.25(n)    CD254010.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.161452 Transcribed sequence with moderate similarity to protein more 80.42(n)    AL925092.1 


    ENSEMBL Gene Tree for DEDD (if available)
    TreeFam Gene Tree for DEDD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DEDD gene
    DEDD22  
    1 SIMAP similar gene for DEDD using alignment to 2 protein entries:     DEDD_HUMAN (see all proteins):
    DEDD2

    DEDD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/122 SNPs in DEDD are shown (see all 122)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1401133931,2
    --161095768(+) ATTCAA/GCAACT 3 -- int10--------
    rs1131625051,2
    F--161095852(+) CTCCAG/ATCACA 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs1381059711,2
    --161095884(+) TAATGC/TTACTT 3 -- int10--------
    rs2004674491,2
    C--161096392(+) CCTCC-/AAAGTG 3 -- int10--------
    rs1436057861,2
    --161096470(+) CTTCTA/GAGATC 3 -- int10--------
    rs784987531,2
    C,F--161096497(+) CCTCAT/CTTCCC 3 -- int11Minor allele frequency- C:0.05NA 120
    rs1866745281,2
    --161096633(+) ACACCC/TCCATC 3 -- int10--------
    rs1924541221,2
    --161096797(+) ATCACC/TATGTA 3 -- int10--------
    rs120453401,2
    C,H--161096803(+) ATGTAC/GTAAAA 3 -- int14Minor allele frequency- G:0.00NS EA 416
    rs1821960981,2
    --161096838(+) TAGATA/CCTACT 3 -- int10--------

    HapMap Linkage Disequilibrium report for DEDD (161090764 - 161102478 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DEDD: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DEDD
    DNA2.0 Custom Variant and Variant Library Synthesis for DEDD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606841    OMIM disorders: --

    3 diseases for DEDD:    About MalaCards
    dental fluorosis    dental caries    breast cancer

    2 diseases from the University of Copenhagen DISEASES database for DEDD:
    Dental caries     Dental fluorosis

    DEDD for disorders           About GeneDecksing


    Export disorders for DEDD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DEDD gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with DEDD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DEDD, a novel death effector domain-containing protein, targeted to the nucleolus. (PubMed id 9774341)1, 2, 3, 9 Stegh A.H.... Peter M.E. (1998)
    2. DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells. (PubMed id 9832420)1, 2, 3, 9 Leo C.P....Hsueh A.J. (1998)
    3. DEDD regulates degradation of intermediate filaments during apoptosis. (PubMed id 12235123)1, 2, 9 Lee J.C....Peter M.E. (2002)
    4. Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC. (PubMed id 11965497)1, 2, 9 Zhan Y....Alnemri E.S. (2002)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. DEDD and DEDD2 associate with caspase-8/10 and signal cell death. (PubMed id 12527898)1, 2 Alcivar A.... Yang X. (2003)
    8. Identification and characterization of DEDD2, a death effector domain-containing protein. (PubMed id 11741985)1, 9 Roth W.... Reed J.C. (2002)
    9. DEDD interacts with PI3KC3 to activate autophagy and a ttenuate epithelial-mesenchymal transition in human breast cancer. (PubMed id 22719072)1 Lv Q....Hu Z.W. (2012)
    10. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9191 HGNC: 2755 AceView: DEDD Ensembl:ENSG00000158796 euGenes: HUgn9191
    ECgene: DEDD H-InvDB: DEDD

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DEDD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DEDD gene:
    Search GeneIP for patents involving DEDD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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