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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DECR2 Gene

protein-coding   GIFtS: 54
GCID: GC16P000451

2,4-Dienoyl CoA Reductase 2, Peroxisomal

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
2,4-Dienoyl CoA Reductase 2, Peroxisomal1 2     SDR17C12
2,4-Dienoyl-CoA Reductase 22 3     Peroxisomal 2,4-Dienoyl-CoA Reductase2
PDCR2 3     Short Chain Dehydrogenase/Reductase Family 17C, Member 12
EC 1.3.1.343 8     pDCR3
Member 11     EC 1.3.18
Short Chain Dehydrogenase/Reductase Family 17C1     

External Ids:    HGNC: 27541   Entrez Gene: 260632   Ensembl: ENSG000002426127   UniProtKB: Q9NUI13   

Export aliases for DECR2 gene to outside databases

Previous GC identifers: GC16P000471 GC16P000391 GC16P000370


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DECR2 Gene: 
DECR2 (2,4-dienoyl CoA reductase 2, peroxisomal) is a protein-coding gene. Diseases associated with DECR2 include tuberculosis, and pneumonia. GO annotations related to this gene include 2,4-dienoyl-CoA reductase (NADPH) activity and nucleotide binding. An important paralog of this gene is HPGD.

UniProtKB/Swiss-Prot: DECR2_HUMAN, Q9NUI1
Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA
esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent
reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain
2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute
a rate limiting step in the peroxisomal degradation of docosahexaenoic acid

Gene Wiki entry for DECR2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010393.16  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DECR2 gene promoter:
         GR   Elk-1   Pax-5   NRSF form 1   GR-beta   NRSF form 2   AREB6   PPAR-alpha   GR-alpha   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDECR2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DECR2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DECR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

DECR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DECR2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P000451:  view genomic region     (about GC identifiers)

Start:
451,826 bp from pter      End:
462,487 bp from pter
Size:
10,662 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DECR2_HUMAN, Q9NUI1 (See protein sequence)
Recommended Name: Peroxisomal 2,4-dienoyl-CoA reductase  
Size: 292 amino acids; 30778 Da
Subunit: Monomer, dimer and oligomer
Subcellular location: Peroxisome (By similarity)
2 PDB 3D structures from and Proteopedia for DECR2:
4FC6 (3D)        4FC7 (3D)    
Secondary accessions: Q6ZRS7 Q96ET0
Alternative splicing: 3 isoforms:  Q9NUI1-1   Q9NUI1-2   Q9NUI1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DECR2: NX_Q9NUI1

Explore proteomics data for DECR2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NUI1

  • 4 DME Specific Peptides for DECR2 (Q9NUI1)
     FITGGGSG  AAGNFLCPA  DAMTRHLAVEWGP  VAFITGGGSGIGFRIAE 

    DECR2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DECR2 Protein Expression
    REFSEQ proteins: NP_065715.1  
    ENSEMBL proteins: 
     ENSP00000219481   ENSP00000400374   ENSP00000399697   ENSP00000402180   ENSP00000395913  
     ENSP00000393382   ENSP00000380822  

    Human Recombinant Protein Products for DECR2: 
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    Novus Biologicals DECR2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for DECR2
    Cloud-Clone Corp. Proteins for DECR2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome ----
    GO:0005778peroxisomal membrane IEA--

    DECR2 for ontologies           About GeneDecksing



    DECR2 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for DECR2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SDRC1: Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 1

    3 InterPro protein domains:
     IPR002347 Glc/ribitol_DH
     IPR002198 DH_sc/Rdtase_SDR
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q9NUI1

    ProtoNet protein and cluster: Q9NUI1

    2 Blocks protein domains:
    IPB002198 Short-chain dehydrogenase/reductase SDR
    IPB002347 Glucose/ribitol dehydrogenase family signature


    UniProtKB/Swiss-Prot: DECR2_HUMAN, Q9NUI1
    Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily


    DECR2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DECR2_HUMAN, Q9NUI1
    Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA
    esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent
    reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain
    2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute
    a rate limiting step in the peroxisomal degradation of docosahexaenoic acid
    Catalytic activity: Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH
    Biophysicochemical properties: Kinetic parameters: KM=59 uM for 2,4-hexadienoyl-CoA; KM=6 uM for
    2,4-decadienoyl-CoA; KM=102 uM for 2,4,7,10,13,16,19-docosaheptaenoyl-CoA; Vmax=1.75 umol/min/mg enzyme toward
    2,4-Hexadienoyl CoA; Vmax=1.37 umol/min/mg enzyme toward 2,4-Decadienoyl CoA;

         Enzyme Numbers (IUBMB): EC 1.3.1.341 2 EC 1.3.12

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding IPI--
    GO:00086702,4-dienoyl-CoA reductase (NADPH) activity IDA11514237
    GO:0016491oxidoreductase activity ----
    GO:0019166trans-2-enoyl-CoA reductase (NADPH) activity IDA10811639
         
    DECR2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Decr2 (no phenotypes)

    DECR2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Decr2tm1Lex for DECR2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for DECR2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DECR2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DECR2 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DECR2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Peroxisome
    Peroxisome

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for DECR2):
        Peroxisome


    DECR2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DECR2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for DECR2 (Q9NUI13 ENSP000002194814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=2 
    CALM2P621583I2D: score=2 
    CALM3P621583I2D: score=2 
    UBCP0CG483I2D: score=1 
    EP300ENSP000002632534STRING: ENSP00000263253
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006636unsaturated fatty acid biosynthetic process IDA11514237
    GO:0008152metabolic process ----

    DECR2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DECR2

    2 HMDB Compounds for DECR2    About this table
    CompoundSynonyms CAS #PubMed Ids
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    NADPH2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23)53-57-6--

    Search CenterWatch for drugs/clinical trials and news about DECR2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DECR2 gene: 
    NM_020664.3  

    Unigene Cluster for DECR2:

    2,4-dienoyl CoA reductase 2, peroxisomal
    Hs.628831  [show with all ESTs]
    Unigene Representative Sequence: AK055839
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000219481(uc002chb.3) ENST00000424398 ENST00000439661 ENST00000437024(uc002chc.3 uc002chd.3)
    ENST00000445291 ENST00000461802(uc021szq.1) ENST00000461947 ENST00000465166
    ENST00000429116 ENST00000461749 ENST00000469922 ENST00000397710
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DECR2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DECR2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DECR2

    Additional mRNA sequence: 

    AJ293009.1 AK055839.1 AK128012.1 AK225961.1 AL442076.1 BC010740.1 BC011968.1 BC030226.1 
    BC127813.1 

    20 DOTS entries:

    DT.441040  DT.95168099  DT.120676517  DT.100779833  DT.97824783  DT.91747917  DT.100779835  DT.100058912 
    DT.100779834  DT.120676539  DT.101983485  DT.97824784  DT.100040062  DT.100779831  DT.120676531  DT.92380828 
    DT.95308232  DT.120676561  DT.91747921  DT.91773982 

    24/477 AceView cDNA sequences (see all 477):

    AK094439 BM750323 BM783577 AJ293009 BM702358 AI871437 BF907205 BI770209 
    BM783291 BM783209 BC030226 BM783312 BG770530 BG057040 AI146511 NM_005009 
    BM772996 AK094340 AA304771 BG116582 BX354074 Z45138 BQ650649 AI126858 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DECR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCTGGGATG
    DECR2 Expression
    About this image


    See DECR2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DECR2

    SOURCE GeneReport for Unigene cluster: Hs.628831
        SABiosciences Expression via Pathway-Focused PCR Array including DECR2: 
              Fatty Acid Metabolism in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DECR2 gene from 8/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Decr21 , 5 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal1, 5 78.77(n)1
    82.19(a)1
      17 (13.06 cM)5
    263781  NM_011933.21  NP_036063.11 
     260812115 
    chicken
    (Gallus gallus)
    Aves LOC1008584081 peroxisomal 2,4-dienoyl-CoA reductase-like 71.38(n)
    73.76(a)
      100858408  XM_003642159.1  XP_003642207.1 
    lizard
    (Anolis carolinensis)
    Reptilia DECR26
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL343518.1(682-23585)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.88722 Xenopus laevis transcribed sequence with moderate similarity more 71.45(n)    BX853535.1 
    zebrafish
    (Danio rerio)
    Actinopterygii decr21 2,4-dienoyl CoA reductase 2, peroxisomal 63.77(n)
    70.14(a)
      406623  NM_213321.1  NP_998486.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPS19(YNL202W)4
    SPS191
    Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme more4
    Sps19p1
    46.37(n)1
    43.15(a)1
      14(259578-260456)4
    8555181, 4  NP_014197.21, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SDRB1 peroxisomal 2,4-dienoyl-CoA reductase 48.43(n)
    44.88(a)
      820462  NM_112116.3  NP_187886.2 
    rice
    (Oryza sativa)
    Liliopsida Os04g06140001 hypothetical protein 49.87(n)
    46.06(a)
      4336980  NM_001060395.1  NP_001053860.1 


    ENSEMBL Gene Tree for DECR2 (if available)
    TreeFam Gene Tree for DECR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DECR2 gene
    HPGD2  DCXR2  CBR42  PECR2  HSD17B142  DHRS22  HSD17B102  BDH22  
    DHRS42  DHRS4L22  HSD17B82  DECR12  
    6 SIMAP similar genes for DECR2 using alignment to 4 protein entries:     DECR2_HUMAN (see all proteins):
    DKFZp547I137    PECR    DECR1    DECR    HSD17B14    CBR4

    DECR2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/409 SNPs in DECR2 are shown (see all 409)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs16982371,2
    C,F,A,H--451306(+) CACAAC/TGCCCG 1 -- us2k15Minor allele frequency- T:0.18NA WA CSA 11
    rs1126193491,2
    C--451338(+) AAAGAG/-GGGGT 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs20073511,2
    C,F--451487(+) TTTTGA/GGAAGC 1 -- us2k13Minor allele frequency- G:0.35WA CSA 122
    rs1916912721,2
    --451522(+) TGGGCC/TCCGGC 1 -- us2k10--------
    rs1445258451,2
    C--451541(+) TGGTGC/TTTACG 1 -- us2k10--------
    rs1831054021,2
    --451663(+) AAAAAC/GACTCG 1 -- us2k10--------
    rs37438891,2
    C--451719(+) CCCCCA/GGCCCC 1 -- us2k10--------
    rs2012379381,2
    C--451985(+) CCGACA/GTGGAG 2 M V mis10--------
    rs1129887051,2
    C--452160(+) GGCTCCTTT/-  
            
    CTTTC
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs19734991,2
    C--452168(+) TCTTTC/TTtctt 1 -- int10--------

    HapMap Linkage Disequilibrium report for DECR2 (451826 - 462487 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for DECR2 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1430579CNV Deletion17803354
    esv2422427CNV Duplication17116639
    nsv457303CNV Loss19166990
    nsv904707CNV Loss21882294
    dgv2473n71CNV Loss21882294
    nsv904711CNV Loss21882294
    dgv2474n71CNV Loss21882294
    nsv904714CNV Loss21882294
    dgv2469n71CNV Loss21882294
    dgv32n68CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for DECR2:    About MalaCards
    tuberculosis    pneumonia


    DECR2 for disorders           About GeneDecksing


    Export disorders for DECR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DECR2 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with DECR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase. (PubMed id 11514237)1, 2, 3 De Nys K.... Van Veldhoven P.P. (2001)
    2. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
    3. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
    7. Why do cellular proteins linked to K63-polyubiquitin c hains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (2013)
    8. Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids. (PubMed id 22745130)2 Hua T.... Liu Z.J. (2012)
    9. Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix. (PubMed id 22002062)1 Okumoto K.... Fujiki Y. (2011)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26063 HGNC: 2754 AceView: NME4andDECR2 Ensembl:ENSG00000242612 euGenes: HUgn26063
    ECgene: DECR2 Kegg: 26063 H-InvDB: DECR2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DECR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DECR2 gene:
    Search GeneIP for patents involving DECR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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