DECR1 Gene
protein-coding GIFtS: 61
GCID: GC08P091082
|
|
2,4-dienoyl CoA reductase 1, mitochondrial
(Previous symbol: DECR)
| |
Aliases
for DECR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| 2,4-Dienoyl CoA Reductase 1, Mitochondrial1 2 | | NADPH2 | | DECR1 2 3 | | Short Chain Dehydrogenase/Reductase Family 18C, Member 12 | | SDR18C11 2 | | 2,4-Dienoyl-CoA Reductase [NADPH]3 | | 2,4-Dienoyl-CoA Reductase, Mitochondrial2 | | 4-Enoyl-CoA Reductase [NADPH]3 | | 4-Enoyl-CoA Reductase2 | | EC 1.3.1.343 |
Export aliases for DECR1 gene to outside databasesPrevious GC identifers: GC08P089445 GC08P090745 GC08P090970 GC08P086223 |
Summaries
for DECR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DECR1:
This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fattyenoyl-CoA esters. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: DECR_HUMAN, Q16698Function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA estershaving double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of2,4-dienoyl-CoA to yield trans-3-enoyl-CoA
|
Genomic Views
for DECR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DECR1 gene promoter:
TBP p53 AP-1 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for DECR1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DECR1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q21.3 Ensembl cytogenetic band: 8q21.3 HGNC cytogenetic band: 8q21.3DECR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P091082: view genomic region
(about GC identifiers)
Start:
|
91,013,580 bp from pter |
End:
|
91,064,320 bp from pter |
Size:
|
50,741 bases |
Orientation:
|
plus strand |
|
Proteins
for DECR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DECR_HUMAN, Q16698 (See
protein sequence)Recommended Name: 2,4-dienoyl-CoA reductase, mitochondrial precursor Size: 335 amino acids; 36068 Da
Subunit: Homotetramer
Subcellular location: Mitochondrion
3 PDB 3D structures from  and Proteopedia  for DECR1:1W6U (3D)
1W73 (3D)
1W8D (3D)
Secondary accessions: Q2M304 Q93085Explore the universe of human proteins at neXtProt for DECR1: NX_Q16698
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16698
DECR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001350.1
ENSEMBL proteins: ENSP00000431045 ENSP00000220764 ENSP00000428533 ENSP00000428701 ENSP00000430561 ENSP00000429551 ENSP00000429779 ENSP00000430759 ENSP00000427936 ENSP00000429096 ENSP00000428162 Reactome Protein details: Q16698
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
DECR1 for ontologies About GeneDecksing
DECR1 Antibody Products:
Assay Products for DECR1: |
Protein
Domains /
Families
for DECR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DECR1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16698ProtoNet protein and cluster: Q16698 2 Blocks protein families: IPB002198 Short-chain dehydrogenase/reductase SDR IPB002347 Glucose/ribitol dehydrogenase family signature
UniProtKB/Swiss-Prot: DECR_HUMAN, Q16698Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily |
Function
for DECR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DECR_HUMAN, Q16698Function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA estershaving double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of2,4-dienoyl-CoA to yield trans-3-enoyl-CoACatalytic activity: Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPHBiophysicochemical properties: Kinetic parameters: KM=7.7 uM for NADPH; KM=14.3 uM for trans-2,trans-4-hexadienoyl-CoA;Vmax=30.3 umol/min/mg enzyme; Genatlas biochemistry entry for DECR1:2-4-dienoyl-CoA reductase,mitochondrial,auxiliary enzyme of beta oxidation participating in the metabolism of (poly)unsaturated fatty enoyl-CoA esters
Enzyme Number (IUBMB): EC 1.3.1.341
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DECR1 (NM_001359) | |  | Sino Biological Human cDNA Clone for DECR1 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DECR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DECR1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DECR1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
DECR1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Decr1tm1Jkh for DECR1
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Decr1):
DECR1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DECR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | | | 3 | Fatty Acid Biosynthesis | | | 4 | Fatty Acid Beta Oxidation | | | 5 | Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for DECR1
5 
Reactome Pathways for DECR1
DECR1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DECR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/9 Interacting proteins for DECR1 (Q166983 ENSP000002207644) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
DECR1 for ontologies About GeneDecksing
|
Drugs & Compounds
for DECR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DECR1
3 HMDB Compounds for DECR1 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| NADP | Adenine-nicotinamide dinucleotide phosphate (see all 18) | 53-59-8 | -- | | NADPH | 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide (see all 23) | 53-57-6 | -- | | trans-3-Hexenoyl-CoA | S-(3E)-3-hexenoate Coenzyme A (see all 9) | 6599-65-1 | -- |
4 DrugBank Compounds for DECR1 About this table
Search CenterWatch for drugs/clinical trials and news about DECR1 / DECR
|
Transcripts
for DECR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DECR1 gene: NM_001359.1 Unigene Cluster for DECR1: 2,4-dienoyl CoA reductase 1, mitochondrial Hs.492212 [show with all ESTs]Unigene Representative Sequence: AK30006918/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000519328 ENST00000220764(uc003yek.1 uc011lgd.1) ENST00000517314
ENST00000521603 ENST00000523447 ENST00000519410 ENST00000517597 ENST00000520859
ENST00000519007 ENST00000522161(uc011lgc.1) ENST00000521668 ENST00000518725
ENST00000517761 ENST00000520227 ENST00000522583 ENST00000524326 ENST00000517301
ENST00000524332
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DECR1 (NM_001359) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DECR1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DECR1 |
Additional cDNA sequence: AK300069.1 BC105080.1 BC105082.1 BC143669.1 L26050.1 U49352.1 21 DOTS entries: DT.445730 DT.91763290 DT.101988009 DT.100667084 DT.97860593 DT.100667088 DT.101988007 DT.75116801 DT.91763289 DT.101988008 DT.121491701 DT.121491703 DT.121491715 DT.121491741 DT.40212783 DT.91763296 DT.91763300 DT.95088605 DT.97860596 DT.95351719 DT.99989901 24/277 AceView cDNA sequences (see all 277): AL524492 W95455 CB164657 CB161458 BM764248 CR590746 BQ720057 BE044384 AV717607 BM850477 CB243029 AI343893 BF333741 BU627280 BE464086 BQ000801 BX111970 AA171918 BI834105 CD216779 CB178422 H72538 N86006 CA488888
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for DECR1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for DECR1
|
Expression
for DECR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DECR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCAAGTCTC
About this image
See DECR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DECR1
SOURCE GeneReport for Unigene cluster: Hs.492212
UniProtKB/Swiss-Prot: DECR_HUMAN, Q16698Tissue specificity: Heart = liver = pancreas > kidney >> skeletal muscle = lung
SABiosciences Expression via Pathway-Focused PCR Arrays including DECR1: | Fatty Acid Metabolism in human mouse rat | | Molecular Toxicology PathwayFinder 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DECR1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DECR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DECR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DECR1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DECR1 |
Orthologs
for DECR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for DECR1 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
DECR11 |
2,4-dienoyl CoA reductase 1, mitochondrial |
78.98(n)
82.17(a) |
|
420218 XM_418328.3 XP_418328.1 |
lizard
(Anolis carolinensis) |
Reptilia |
DECR16DECR26(see all 3) |
-- |
76(a)30(a)(see all 3) |
1 ↔ 1possible ortholog(see all 3) |
4(21450950-21459345) GL343518.1(6821-19709) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.222262 |
Xenopus laevis transcribed sequence with moderate similarity more |
76.7(n) |
|
BU908850.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufe38b072 |
Transcribed sequence with weak similarity to protein more |
74.34(n) |
|
CK028771.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
F53C11.33 |
2,4-dienoyl-CoA reductase |
52(a)
(best of 3) |
|
V(13785003-13786145) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
SDRB6 |
peroxisomal 2,4-dienoyl-CoA reductase |
27(a) |
possible ortholog |
3(4063323-4064822) |
rice
(Oryza sativa) |
Liliopsida |
-- |
oxidoreductase, short chain dehydrogenase/reductas... |
26(a) |
possible ortholog |
4(30954063-30956535) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
kduD6hdhA6(see all 5) |
2-deoxy-D-gluconate 3-dehydrogenase7-alpha-hydroxysteroid dehydrogenase, NAD-dependen...(see all 5) |
24(a)24(a)(see all 5) |
possible orthologpossible ortholog(see all 5) |
Chromosome(2980519-2981280) Chromosome(1695297-1696064) |
ENSEMBL Gene Tree for DECR1 (if available)
TreeFam Gene Tree for DECR1 (if available) |
Paralogs
for DECR1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DECR1 gene
- DCXR2 DECR22 PECR2 HSD17B142 DHRS22 BDH22 DHRS42 DHRS4L22
4 SIMAP similar genes for DECR1 using alignment to 9 protein entries: DECR_HUMAN (see all proteins):DECR PECR DECR2 HSD17B14
DECR1 for paralogs About GeneDecksing
|
Genomic Variants
for DECR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DECR1 (91013580 - 91064320 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DECR1
2 CNVs: 3740 31449 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DECR1 |
|
Disorders
/ Diseases
for DECR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DECR1 for disorders About GeneDecksing
OMIM gene information: 222745
OMIM disorders: --
17  diseases for DECR1: About MalaCardsdecr deficiency cerebrovascular accident toxic encephalopathy chronic granulomatous disease
hirschsprung's disease huntington's disease brain disease nephropathy
hypercholesterolemia parkinson's disease hyperglycemia pertussis
dementia arthritis tuberculosis malaria
mycobacterium tuberculosis
10 diseases from the University of Copenhagen DISEASES database for DECR1:Chronic granulomatous disease Glucosephosphate dehydrogenase deficiency Diabetes mellitus Hypertension
Cancer Malaria Chagas disease Hyperglycemia
Atherosclerosis Anemia Human Genome Epidemiology (HuGE) Navigator: DECR1 (4 documents)
Export disorders for DECR1 gene to outside databases
|
Publications
for DECR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DECR1 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with DECR1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and characterization of cDNA for human 120 kDa mitochondrial 2,4-dienoyl-coenzyme A reductase. (PubMed id 7818482)1, 2, 3 Koivuranta K.T.... Hiltunen J.K. (1994)
- Molecular cloning and characterization of the human mitochondrial 2,4-dienoyl-CoA reductase gene (DECR). (PubMed id 9403065)1, 2, 9 Helander H.M.... Hiltunen J.K. (1997)
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)1, 2 Nusbaum C....Lander E.S. (2006)
- Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. (PubMed id 15531764)1, 2 Alphey M.S.... Hunter W.N. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Identification of proteins associated with ligand-acti vated estrogen receptor a in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)1 Tarallo R....Weisz A. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
|
External Searches for DECR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DECR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DECR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DECR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DECR1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/DECR1 |
|
| | |
About This Section
| Patent Information for DECR1 gene:
Search GeneIP for patents involving DECR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for DECR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for DECR1 | | OriGene shRNA RFP for DECR1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DECR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DECR1 | | | OriGene Protein Over-expression Lysate for DECR1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DECR1 | | OriGene 3'-UTR Clone for DECR1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DECR1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DECR1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DECR1 | | OriGene Custom Protein Services for DECR1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DECR1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DECR1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DECR1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DECR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DECR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DECR1 |
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| | | | Search Tocris compounds for DECR1 |
| |  |  |  |  | | | | | | Recombinant Protein for DECR1 |
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 | | | DECR1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DECR1 |
|  |  |  | | | | ThermoFisher Antibody for DECR1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DECR1 |
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