Aliases for DECR1 Gene
External Ids for DECR1 Gene
Previous HGNC Symbols for DECR1 Gene
Previous GeneCards Identifiers for DECR1 Gene
This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]
GeneCards Summary for DECR1 Gene
DECR1 (2,4-Dienoyl-CoA Reductase 1, Mitochondrial) is a Protein Coding gene. Diseases associated with DECR1 include 2,4-Dienoyl-Coa Reductase Deficiency and Chronic Granulomatous Disease. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Metabolism. GO annotations related to this gene include oxidoreductase activity and NADPH binding. An important paralog of this gene is DECR2.
UniProtKB/Swiss-Prot for DECR1 Gene
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.