DEAF1 Gene
protein-coding GIFtS : 61 GCID: GC11 M000634
DEAF1 transcription factor deformed epidermal autoregulatory factor 1 (Drosophila)...
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Aliasesfor DEAF1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases DEAF1 Transcription Factor 1 2 Zinc Finger MYND Domain-Containing Protein 52 3 NUDR1 2 3 Deformed Epidermal Autoregulatory Factor 1 (Drosophila)1 SPN1 2 3 Deformed Epidermal Autoregulatory Factor 1 Homolog2 ZMYND51 2 3 Suppressin3 Nuclear DEAF-1-Related Transcriptional Regulator2 3 Suppressin3
Export aliases for DEAF1 gene to outside databases Previous GC identifers: GC11U990192 GC11P000842 GC11P000502 GC11M000637 GC11M000638 GC11M000460
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Summariesfor DEAF1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: DEAF1_HUMAN, O75398 Function : Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its ownpromoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm
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Genomic Viewsfor DEAF1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000011.9 NC_018922.1 NT_009237.18 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DEAF1 gene promoter:E2F-3a E2F-4 E2F-5 GCNF E2F-2 c-Ets-1 SRY E2F-1 E2F GCNF-1 Other transcription factors Search SABiosciences Chromatin IP Primers for DEAF1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5 DEAF1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11M000634: view genomic region
(about GC identifiers )
Start: 644,225 bp from pter End:
706,715 bp from pter
Size: 62,491 bases Orientation:
minus strand
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Proteinsfor DEAF1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: DEAF1_HUMAN, O75398 See
protein sequence )Recommended Name: Size : 565 amino acids; 59327 DaSubunit : Homodimer (Probable). Isoform 1 and isoform 4 may form a heterodimer. Binds to LMO4 (via its C-terminus), LMO2and CLIM2 (By similarity). May interact with the corepressor NCOR
Subcellular location : Isoform 1: Nucleus. Cytoplasm. Note=Cytoplasmic in non-mucinous colorectal carcinoma. Whenexpressed alone, localized almost exclusively in the nucleus but, when expressed with isoform 4, nuclear expression decreases to 32% and cytoplasmic expression increases by 270%
Subcellular location : Isoform 2: Secreted. Note=Secreted in some cell typesSubcellular location : Isoform 3: Secreted. Note=Secreted in some cell typesSubcellular location : Isoform 4: Cytoplasm. Nucleus. Note=When expressed alone, localizes mainly in the cytoplasm but,when expressed with isoform 1, nuclear localization is enhanced
Miscellaneous : Defective DEAF1 could confer a growth advantage to the mutated cells influencing the development andprogression of neoplasia, e.g. in the case of colorectal carcinomas. Subcellular location in colorectal carcinomas (cytoplasmic or nuclear) is a prognostic factor that identifies a subgroup of patients with reduced survival. In addition, changes in the subcellular location correlates with the proliferative status of the cells
Caution : This protein was first known as suppressin (characterized in bovine neuroendocrine and immune cells). However,according to PubMed:9773984, it is uncertain whether it corresponds really to the suppressin also described in Ref.4. DEAF1 has been described as a nuclear dimeric protein and suppressin as a secreted monomeric protein
2 PDB 3D structures from :2JW6 (3D) 4A24 (3D) Secondary accessions : A8K1F8 A8K5R8 C7T5V5 O15152 O75399 O75510 O75511 O75512 O75513 Q9UET1Alternative splicing : 4 isoforms : O75398-1 O75398-3 O75398-4 O75398-5 (Has no predictable signal peptide. Ref.2 (AAC25718/AAC25719) sequences differ from that shown due to frameshifts in positions 222 and 236)Explore the universe of human proteins at neXtProt for DEAF1: NX_O75398 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O75398 DEAF1 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_066288.2 ENSEMBL proteins: ENSP00000431563 ENSP00000371846 ENSP00000432518 ENSP00000341902 Human Recombinant Protein Products for DEAF1: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing DEAF1 Antibody Products: Assay Products for DEAF1:
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Protein
Domains /for DEAF1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry O75398 ProtoNet protein and cluster: O75398
3 Blocks protein families : IPB000770 IPB002893 IPB010919 UniProtKB/Swiss-Prot: DEAF1_HUMAN, O75398 Similarity : Contains 1 MYND-type zinc fingerSimilarity : Contains 1 SAND domain
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Functionfor DEAF1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: DEAF1_HUMAN, O75398 Function : Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its ownpromoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for DEAF1 :4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Deaf1) :About GeneDecksing Animal Models: Deaf1 tm1Sho for DEAF1Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DEAF1 (NM_021008 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DEAF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DEAF1
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEAF1
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Pathways & Interactionsfor DEAF1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 SIDS Susceptibility Pathways
1 Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DEAF1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)5/27 Interacting proteins for DEAF1 (O75398 1 , 2 , 3 ENSP00000371846 4 via UniProtKB, MINT, STRING , and/or I2D (see all 27 )About this table Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7 ): About this table
About GeneDecksing
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Drugs & Compoundsfor DEAF1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for DEAF1 2 Novoseek chemical compound relationships for DEAF1 gene About this table DEAF1
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Transcriptsfor DEAF1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for DEAF1 gene: NM_021008.2 Unigene Cluster for DEAF1:
DEAF1 transcription factor Hs.243994 [show with all ESTs ] Unigene Representative Sequence: NM_021008 13 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000527170 (uc009ycf.1 ) ENST00000382409 (uc001lqq.1 uc021qbn.1 )ENST00000527658 ENST00000525904 ENST00000530813 ENST00000526790 ENST00000529717 ENST00000525626 ENST00000528864 ENST00000524786 ENST00000529727 ENST00000526857 ENST00000338675 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DEAF1 (NM_021008 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DEAF1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DEAF1
Additional cDNA sequence: AB209831.1 AF007165.1 AF049459.1 AF049460.1 AF068892.1 AF068894.1 AF068897.1 AK289873.1 AK291383.1 BC042135.1 BC053322.1 FJ985253.1
12 DOTS entries : DT.97855153 DT.100780172
DT.80101339 DT.91956044 DT.206301 DT.100780170 DT.120701886 DT.100780175 DT.101983502 DT.120701927 DT.120701935 DT.91644161 24/250 AceView cDNA sequences (see all 250 ):
BU784389 BU789587 CA446276 BM011151 BQ228380 T31308 BQ267882 CA454295 T16442 BQ053028 AI929566 T33232 BC053322 BM678787 CF454194 BQ227969 AW801885 AL119706 BM701201 BM806849 BU556875 BM696110 BU948066 Z42855 GeneLoc Exon Structure 5/8 Alternative Splicing Database (ASD) splice patterns (SP) for DEAF1 (see all 8 ) About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b · 16c SP1 : - - - - - - - SP2 : - - - - - SP3 : - - - - - - - - SP4 : - - - SP5 : - -
ECgene alternative splicing isoforms for DEAF1
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Expression for DEAF1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section DEAF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AGCGTCCGGTAbout this image DEAF1 expression in embryonic tissues and stem cells About this table
See DEAF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DEAF1 SOURCE GeneReport for Unigene cluster: Hs.243994 UniProtKB/Swiss-Prot: DEAF1_HUMAN, O75398 Tissue specificity : Expressed in various tissues and cells such as in peripheral mononuclear cells andhormone-secreting pituitary cells. Expression in pancreatic lymph nodes of patients with type 1 diabetes is 20 times higher than in healthy controls SABiosciences Custom PCR Arrays for DEAF1 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEAF1
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Orthologsfor DEAF1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for DEAF1 gene from 5/14 species (see all 14 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Deaf11 5
deformed epidermal autoregulatory factor 1 (Drosophila)1, 5
85.19(n) 1 93.63(a) 1
7 (86.61 cM) 5 54006 1 NM_016874.2 1 NP_058570.1 1 141297176 5
chicken Aves DEAF11
deformed epidermal autoregulatory factor 1 (Drosophila)
78.29(n) 84.59(a)
423017 NM_001137649.1 NP_001131121.1
lizard Reptilia DEAF16
--
77(a)
1 ↔ 1
1(74134873-74168316)
zebrafish Actinopterygii zgc:1948951
zgc:194895
65(n) 63.12(a)
563776 NM_001130779.1 NP_001124251.1
fruit fly Insecta Deaf13
biological_process unknown RNA polymerase IImore
54(a)
--
ENSEMBL Gene Tree for DEAF1 (if available)TreeFam Gene Tree for DEAF1 (if available)
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Paralogsfor DEAF1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section
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Genomic Variantsfor DEAF1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 11 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for DEAF1 (644225 - 706715 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 10 variations for DEAF1 5 CNVs 101102 3831 29884 4725 29883 5 Indels 44924 44921 44925 24784 24780 Human Gene Mutation Database (HGMD) : DEAF1 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor DEAF1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 602635
OMIM disorders : --5 : About MalaCards letterer-siwe disease major depressive disorder osteoarthritis adenocarcinoma pancreatitis 2 diseases from the University of Copenhagen DISEASES database for DEAF1 :Letterer-Siwe disease Panic disorder 2 Novoseek disease relationships for DEAF1 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
tumors
0
2
11705868 (1)
cancer
0
3
10521432 (1)
Export disorders for DEAF1 gene to outside databases
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Publicationsfor DEAF1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for DEAF1 gene, integrated from 9 sources (see all 35 ):(articles sorted by number of sources associating them with DEAF1) Utopia : connect your pdf to the dynamic
Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein. (PubMed id 9773984) 1 , 2 , 3, 9(1998) Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas. (PubMed id 11705868) 1 , 2 , 9(2001) Nuclear DEAF-1-related (NUDR) protein contains a novel DNA binding domain and represses transcription of the heterogeneous nuclear ribonucleoprotein A2/B1 promoter. (PubMed id 10521432) 1 , 2 , 9(1999) Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. (PubMed id 19668219) 1 , 2 (2009) Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland. (PubMed id 18826651) 1 , 2 (2008) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation. (PubMed id 11427895) 1 , 2 (2001) Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder. (PubMed id 18561871) 1 , 9(2009) Identification of a nuclear export signal and protein interaction domains in deformed epidermal autoregulatory factor-1 (DEAF-1). (PubMed id 15161925) 1 , 9(2004) Functional analysis of the osteoarthritis susceptibil ity-associated GDF5 regulatory polymorphism. (PubMed id 19565498) 1 , 9(2009)
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External Searches for DEAF1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing DEAF1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing DEAF1 gene
(According to HUGE )
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Specialized Databases showing DEAF1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for DEAF1 gene: DEAF1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor DEAF1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for DEAF1 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for DEAF1 OriGene 3'-UTR Clone for DEAF1 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for DEAF1 OriGene Custom Protein Services for DEAF1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DEAF1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for DEAF1
DEAF1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DEAF1
ThermoFisher Antibodies for DEAF1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DEAF1
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Aliases for DEAF1
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Expression for DEAF1
Function for DEAF1
Genomic Views for DEAF1
Intellectual Property for DEAF1
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and Proteopedia 
for DEAF1:
Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
Microarrays
