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DDX56 Gene

protein-coding   GIFtS: 53
GCID: GC07M044571

DEAD (Asp-Glu-Ala-Asp) Box Helicase 56

(Previous name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 56)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD (Asp-Glu-Ala-Asp) Box Helicase 561 2     61-Kd Nucleolar Helicase2
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 561 2     DDX262
Nucleolar Helicase Of 61 KDa1 2     DEAD-Box RNA Helicase2
DDX212 3     Probable ATP-Dependent RNA Helicase DDX562
NOH612 3     Putative Nucleolar RNA Helicase2
ATP-Dependent 61 KDa Nucleolar RNA Helicase2 3     EC 3.6.4.133
DEAD Box Protein 212 3     EC 3.6.18
DEAD Box Protein 562 3     

External Ids:    HGNC: 181931   Entrez Gene: 546062   Ensembl: ENSG000001362717   OMIM: 6080235   UniProtKB: Q9NY933   

Export aliases for DDX56 gene to outside databases

Previous GC identifers: GC07M044311 GC07M044346 GC07M044378 GC07M044489


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DDX56 Gene:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes
involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial
splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The
protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with
nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during
assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Mar 2012)

GeneCards Summary for DDX56 Gene:
DDX56 (DEAD (Asp-Glu-Ala-Asp) box helicase 56) is a protein-coding gene. GO annotations related to this gene include RNA binding and ATP-dependent RNA helicase activity.

UniProtKB/Swiss-Prot: DDX56_HUMAN, Q9NY93
Function: May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S
ribosomal subunits. Has intrinsic ATPase activity

Gene Wiki entry for DDX56 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007819.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX56 gene promoter:
         AP-1   MyoD   Nkx2-5   Tal-1beta   GATA-1   Arnt   POU2F1   POU2F1a   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): DDX56 promoter sequence
   Search Chromatin IP Primers for DDX56

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX56


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p13   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13

DDX56 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX56 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M044571:  view genomic region     (about GC identifiers)

Start:
44,605,016 bp from pter      End:
44,614,650 bp from pter
Size:
9,635 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 44,644,923-44,653,656     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DDX56_HUMAN, Q9NY93 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX56  
Size: 547 amino acids; 61590 Da
Subunit: May form homooligomeric complexes
Secondary accessions: A4D2K9 C9JV95 Q6IAE2 Q9H9I8
Alternative splicing: 2 isoforms:  Q9NY93-1   Q9NY93-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DDX56: NX_Q9NY93

Explore proteomics data for DDX56 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys45
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for DDX56 (Q9NY93)
     VLNFDLP  ARTGSGKT  LDPRLLQA  IPLALEGKD 


    See DDX56 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001244118.1  NP_061955.1  

    ENSEMBL proteins: 
     ENSP00000258772   ENSP00000402989   ENSP00000392139   ENSP00000411456   ENSP00000393488  
     ENSP00000390553   ENSP00000388310  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    5 InterPro protein domains:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q9NY93

    ProtoNet protein and cluster: Q9NY93

    UniProtKB/Swiss-Prot: DDX56_HUMAN, Q9NY93
    Similarity: Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with DDX56           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX56_HUMAN, Q9NY93
    Function: May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S
    ribosomal subunits. Has intrinsic ATPase activity
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): Selected molecular function terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding ----
    GO:0003723RNA binding ----
    GO:0004004ATP-dependent RNA helicase activity TAS10749921
    GO:0004386helicase activity ----
         
    Find genes that share ontologies with DDX56           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for DDX56:
     Decreased circadian period len  Increased G1 DNA content  Nuclear 60S biogenesis defects 

    Animal Models:
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    hsa-mir-331-3p (MIRT043450), hsa-mir-423-3p (MIRT042629), hsa-mir-34a-5p (MIRT025272), hsa-mir-92a-3p (MIRT049377), hsa-mir-328-3p (MIRT043777)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DDX56_HUMAN, Q9NY93: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--

    Find genes that share ontologies with DDX56           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX56
    Interactions:

        Search GeneGlobe Interaction Network for DDX56

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DDX56 (Q9NY933 ENSP000002587724) via UniProtKB, MINT, STRING, and/or I2D (see all 220)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H2BCP628073, ENSP000003217444I2D: score=2 STRING: ENSP00000321744
    HIST1H2BFP628073, ENSP000003530744I2D: score=2 STRING: ENSP00000353074
    HIST1H2BEP628073I2D: score=2 
    HIST1H2BGP628073I2D: score=2 
    HIST1H2BIP628073I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process TAS10749921
    GO:0006364rRNA processing IEA--

    Find genes that share ontologies with DDX56           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX56



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DDX56 gene (2 alternative transcripts): 
    NM_001257189.1  NM_019082.3  

    Unigene Cluster for DDX56:

    DEAD (Asp-Glu-Ala-Asp) box helicase 56
    Hs.654762  [show with all ESTs]
    Unigene Representative Sequence: AK125595
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258772 ENST00000446987 ENST00000421223(uc003tlg.3 uc003tlh.3 uc010kyg.3 uc010kyh.1)
    ENST00000479602 ENST00000485367 ENST00000467318 ENST00000433257 ENST00000431640
    ENST00000448192 ENST00000415758 ENST00000473924 ENST00000479440
    miRNA
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    Additional mRNA sequence: 

    AF247666.1 AJ131712.1 AK022774.1 AK125595.1 AK222662.1 AK309276.1 AK315363.1 AL136700.1 
    BC001235.1 CR457213.1 

    13 DOTS entries:

    DT.450087  DT.99981100  DT.40240271  DT.100795338  DT.92453032  DT.121116498  DT.95157793  DT.121116504 
    DT.95157796  DT.100839867  DT.91960946  DT.92453012  DT.95157804 

    Selected AceView cDNA sequences (see all 854):

    AA773437 BE349378 BU947623 BU947547 BM511814 AI554936 BM992460 BE906815 
    BC001235 CB109004 BG476507 BI520364 CR614178 BM424200 BQ130550 BM916417 
    BM994270 AI299602 BQ684066 AW517955 AI302364 BM549469 AA365286 CD672035 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DDX56 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a ·
    SP1:                                                                    -                                               -                                       
    SP2:                                                                    -                                                                                       
    SP3:                                                                                                                                                            
    SP4:                                                                    -                                                                                       
    SP5:                                                                    -                                                                                       

    ExUns: 15b ^ 16
    SP1:  -         
    SP2:  -         
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for DDX56

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX56 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCCTGACTA
    DDX56 Expression
    About this image

    DDX56 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX56 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654762

    UniProtKB/Swiss-Prot: DDX56_HUMAN, Q9NY93
    Tissue specificity: Detected in heart, brain, liver, pancreas, placenta and lung

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX56 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx561 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 561, 5 85.47(n)1
    91.03(a)1
      11 (3.94 cM)5
    525131  NM_026538.31  NP_080814.11 
     62589195 
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ620420.12   -- 73.36(n)    BJ620420.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx561 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 63.17(n)
    66.29(a)
      445399  NM_001003876.1  NP_001003876.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hlc1 Helicase 55.17(n)
    50.6(a)
      33118  NM_078710.4  NP_523434.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C24H12.41 CELE_C24H12.4 52.03(n)
    45.29(a)
      173432  NM_170970.5  NP_740966.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DBP9(YLR276C)4
    DBP91
    ATP-dependent RNA helicase of the DEAD-box family involved more4
    DBP91
    50.32(n)1
    46.96(a)1
      12(696830-695046)4
    8509821, 4  NP_013378.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G349101 AT4G34910 47.3(n)
    41.89(a)
      829643  NM_119657.2  NP_195217.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g07288001 Os03g0728800 49.72(n)
    42.53(a)
      4333983  NM_001057684.1  NP_001051149.1 


    ENSEMBL Gene Tree for DDX56 (if available)
    TreeFam Gene Tree for DDX56 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX56 gene
    Selected SIMAP similar genes for DDX56 using alignment to 6 protein entries:     DDX56_HUMAN (see all proteins) (see all similar genes):
    DDX23    DDX19A    DDX24    EIF4A3    DDX19B    DDX25
    DDX55    DDX39A    EIF4A1    DDX39B    DDX31    DDX54
    DDX4    DDX41    mcdrh    DDX10    DDX5    EIF4A2

    Find genes that share paralogs with DDX56           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for DDX56
    PGOHUM00000245043


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX56 (see all 385)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1456684791,2
    --44604543(+) AATATC/TGTCTG 2 -- ds50010--------
    rs1484025741,2
    C--44604603(+) CTGCCC/TCCATC 2 -- ds50010--------
    rs1813162701,2
    --44604730(+) TCCTTC/TGTCTC 2 -- ds50010--------
    rs1450593691,2
    --44604752(+) TTGCCA/GAGAAA 2 -- ds50010--------
    rs1475854121,2
    --44604789(+) GGCACA/TCTCCT 2 -- ds50010--------
    rs1843604941,2
    --44604879(+) TGCAAC/TCTAGG 2 -- ds50010--------
    rs1152525261,2
    F--44604951(+) AGGGCA/GTAAGG 2 -- ds50011Minor allele frequency- G:0.01WA 118
    rs353962491,2
    C--44604967(+) TACAC-/ATGTGTG 2 -- ds50010--------
    rs788242741,2
    C--44604968(+) ACACAC/TGTGTG 2 -- ds50010--------
    rs1420280021,2
    C--44605059(+) AGCTGC/TCCCGG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for DDX56 (44605016 - 44614650 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DDX56: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing DDX56
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX56

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608023    OMIM disorders: --


    Find genes that share disorders with DDX56           About GenesLikeMe

    Genetic Association Database (GAD): DDX56

    Export disorders for DDX56 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX56 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with DDX56)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel helicase-type protein in the nucleolus: protein NOH61. (PubMed id 10749921)1, 2, 3, 9 Zirwes R.F.... Schmidt-Zachmann M.S. (Mol. Biol. Cell 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    5. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    9. The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles. (PubMed id 22925334)1 Xu Z. and Hobman T.C. (Virology 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54606 HGNC: 18193 AceView: DDX56andHNLF Ensembl:ENSG00000136271 euGenes: HUgn54606
    ECgene: DDX56 H-InvDB: DDX56

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX56 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DDX56 gene:
    Search GeneIP for patents involving DDX56

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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