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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DDX51 Gene

protein-coding GIFtS: 49
GCID: GC12M132621

DEAD (Asp-Glu-Ala-Asp) box polypeptide 51

Explore 1 disease affiliated with
DDX51 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 51¹ ²
DEAD Box Protein 51² ³
ATP-Dependent RNA Helicase DDX51²
EC 3.6.4.13³
EC 3.6.1⁸

External Ids:	HGNC: 20082¹	Entrez Gene: 317781²	Ensembl: ENSG00000185163⁷	UniProtKB: Q8N8A6³

Export aliases for DDX51 gene to outside databases

Previous GC identifers: GC12M132503 GC12M131117 GC12M131289 GC12M129506

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DDX51_HUMAN, Q8N8A6

Function: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009755.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DDX51 gene promoter:
AML1a Brachyury YY1 GATA-1 HEN1 PPAR-alpha PPAR-gamma1 Ik-2 PPAR-gamma2 Pax-4a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for DDX51

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX51

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.33 Ensembl cytogenetic band: 12q24.33 HGNC cytogenetic band: 12q24.33

DDX51 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX51 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M132621: view genomic region (about GC identifiers)

Start:	132,621,139 bp from pter	End:	132,628,880 bp from pter
Size:	7,742 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DDX51_HUMAN, Q8N8A6 (See protein sequence)

Recommended Name: ATP-dependent RNA helicase DDX51

Size: 666 amino acids; 72457 Da

Subcellular location: Nucleus, nucleolus (By similarity)

Secondary accessions: A8MPT9 Q5CZ71 Q8IXK5 Q96ED1

Explore the universe of human proteins at neXtProt for DDX51: NX_Q8N8A6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N8A6

4/9 DME Specific Peptides for DDX51 (Q8N8A6) (see all 9)

RVGRTAR

VATPGRL

IVVATPGR

DEADRMID

DDX51 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_778236.2

ENSEMBL proteins:

ENSP00000380495

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	GenScript Custom Purified and Recombinant Proteins Services for DDX51
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DDX51

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005730	nucleolus	IEA	--

DDX51 for ontologies About GeneDecksing

DDX51 Antibody Products:

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	Novus Biologicals DDX51 Antibodies
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	Uscn Antibodies for DDX51
	Search ThermoFisher Antibodies for DDX51

Assay Products for DDX51:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for DDX51
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for DDX51

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DDX51 for domains About GeneDecksing

4 InterPro domains/families:

IPR011545 DNA/RNA_helicase_DEAD/DEAH_N

IPR000629 RNA-helicase_DEAD-box_CS

IPR014001 Helicase_ATP-bd

IPR001650 Helicase_C

Graphical View of Domain Structure for InterPro Entry Q8N8A6

ProtoNet protein and cluster: Q8N8A6

1 Blocks protein family: IPB000629 ATP-dependent helicase

UniProtKB/Swiss-Prot: DDX51_HUMAN, Q8N8A6

Domain: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding

and hydrolysis

Similarity: Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily

Similarity: Contains 1 helicase ATP-binding domain

Similarity: Contains 1 helicase C-terminal domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DDX51_HUMAN, Q8N8A6

Function: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits (By similarity)

Catalytic activity: ATP + H(2)O = ADP + phosphate

Enzyme Numbers (IUBMB): EC 3.6.1² EC 3.6.4.13¹

miRNA Products:		OriGene 3'-UTR Clone: DDX51 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX51
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DDX51
		SwitchGear 3'UTR luciferase reporter plasmid: DDX51 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX51 (see all 7) OriGene shRNA RFP: DDX51 OriGene siRNA: DDX51
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX51

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for DDX51

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX51 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX51 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DDX51 (NM_175066)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX51

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DDX51
		Search LifeMap BioReagents cell lines for DDX51

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX51

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003723	RNA binding	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0008026	ATP-dependent helicase activity	IEA	--

DDX51 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for DDX51:

Decreased Wnt reporter activit

Decreased viability

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DDX51

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

5/47 Interacting proteins for DDX51 (Q8N8A6³ ENSP00000380495⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 47)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HIST1H4A	P62805³	I2D: score=1
HIST1H4B	P62805³	I2D: score=1
HIST1H4C	P62805³	I2D: score=1
HIST1H4D	P62805³	I2D: score=1
HIST1H4E	P62805³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006364	rRNA processing	IEA	--

DDX51 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DDX51
Search CenterWatch for drugs/clinical trials and news about DDX51

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DDX51 gene:

NM_175066.3

Unigene Cluster for DDX51:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 51

Hs.445168 [show with all ESTs]

Unigene Representative Sequence: NM_175066

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000397333(uc001ujy.4) ENST00000462829 ENST00000541489 ENST00000329073

ENST00000545991 ENST00000546058

miRNA Products:		OriGene 3'-UTR Clone: DDX51 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX51
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DDX51
		SwitchGear 3'UTR luciferase reporter plasmid: DDX51 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX51 (see all 7) OriGene shRNA RFP: DDX51 OriGene siRNA: DDX51
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX51

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX51 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX51 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DDX51 (NM_175066)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX51
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX51

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX51 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX51
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX51

Additional cDNA sequence:

AB593157.1 AK097078.1 BC012461.2 BC029279.1 BC040185.2 BC063603.1 CR936870.1

9 DOTS entries:

DT.217379 DT.95161270 DT.65285830 DT.92424969 DT.106779 DT.92424968 DT.101968309 DT.91987047

DT.99935909

24/113 AceView cDNA sequences (see all 113):

AI383509 CF134951 AA808631 AW664182 BM786490 CK430932 BC029279 AI245102

CK430701 BM808782 AA157876 BX115040 AA157438 BF684837 BC012461 AA972948

BM826115 BU543659 AI934630 AI951143 CD370946 BM557347 BC063603 AA905768

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for DDX51 About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b	·	7c	·	7d	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14
SP1:																					-				-
SP2:
SP3:
SP4:
SP5:																									-

ECgene alternative splicing isoforms for DDX51

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DDX51 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACTGGGTGG

About this image

DDX51 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Atrioventricular Canal

Atrioventricular Canal Cells

Myocardium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DDX51 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DDX51

SOURCE GeneReport for Unigene cluster: Hs.445168

SABiosciences Custom PCR Arrays for DDX51

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX51 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX51
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX51

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX51

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DDX51 gene from 8/33 species (see all 33) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	DDX51¹	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	61.55(n) 60.83(a)		416936 XM_415229.2 XP_415229.2
African clawed frog (Xenopus laevis)	Amphibia	Xl.13840²	Xenopus laevis transcribed sequence with weak similarity more	72.11(n)		BJ076671.1
zebrafish (Danio rerio)	Actinopterygii	Dr.4368²	Transcribed sequence with strong similarity to protein more	70.22(n)		AI878720.1
fruit fly (Drosophila melanogaster)	Insecta	Dbp73D¹	Dead box protein 73D	48.18(n) 43.79(a)		39871 NM_057485.3 NP_476833.1
worm (Caenorhabditis elegans)	Secernentea	ZK686.2⁶	Putative ATP-dependent RNA helicase ZK686.2	17(a)	1 ↔ 1	III(7763634-7765987)
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	DBP6¹	Dbp6p	42.97(n) 38.11(a)		855774 NP_014436.1
thale cress (Arabidopsis thaliana)	eudicotyledons	RH1¹	RNA helicase 1	46.61(n) 41.4(a)		827266 NM_117677.6 NP_193320.6
rice (Oryza sativa)	Liliopsida	Os02g0795900¹	hypothetical protein	48.3(n) 42.4(a)		4331005 NM_001054921.1 NP_001048386.1

ENSEMBL Gene Tree for DDX51 (if available)
TreeFam Gene Tree for DDX51 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs71453135^1,2	C	--	132620570(+)	`TGCCC-/ACGGTG`	1	--	int¹		2		NA	4
rs181006134^1,2		--	132620846(+)	`CCTCCC/TACCTC`	1	--	int¹		0	--	--	--	--
rs186039752^1,2		--	132620860(+)	`AGTGTA/GCCCAC`	1	--	int¹		0	--	--	--	--
rs11831960^1,2	C,A,H,	--	132620895(+)	`AGTGTA/GCCCAC`	1	--	int¹		0	--	--	--	--
rs184056809^1,2		--	132620937(+)	`CCCACA/GGTGCC`	1	--	int¹		0	--	--	--	--
rs35618536^1,2	C	--	132620954(+)	`CACCT-/CCCCGA`	1	--	int¹		0	--	--	--	--
rs9788144^1,2	C,F,H,	--	132620992(+)	`GTCTGC/TGAACC`	1	--	int¹		10		NS EA NA	1190
rs117806012^1,2	F,	--	132620993(+)	`TCTGCG/AAACCC`	1	--	int¹		2		NA EA	240
rs113428610^1,2	C,	--	132621022(+)	`TCAATC/TCCCGA`	1	--	int¹		2		CSA WA	120
rs141769024^1,2		--	132621251(+)	`CTGTCA/GCCAGG`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DDX51 (132621139 - 132628880 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DDX51
2 CNVs: 29932 29931

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX51

DNA2.0 Custom Variant and Variant Library Synthesis for DDX51

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DDX51 for disorders About GeneDecksing

1 disease for DDX51: About MalaCards

malaria

Export disorders for DDX51 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DDX51 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with DDX51)

Utopia: connect your pdf to the dynamic
world of online information

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)¹ Oshikawa M.... Kato S. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 317781	HGNC: 20082	AceView: DDX51	Ensembl:ENSG00000185163	euGenes: HUgn317781
ECgene: DDX51	H-InvDB: DDX51

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DDX51	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DDX51 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DDX51 gene:
Search GeneIP for patents involving DDX51

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for DDX51
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX51		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX51
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DDX51
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	GenScript Custom Purified and Recombinant Proteins Services for DDX51		GenScript cDNA clones with any tag delivered in your preferred vector for DDX51
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX51

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX51

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes DDX51 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

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DDX51 Gene

DEAD (Asp-Glu-Ala-Asp) box polypeptide 51

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for DDX51 gene

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for DDX51 gene

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Proteins
for DDX51 gene

Protein Domains /
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for DDX51 gene

Function
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Pathways & Interactions
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Transcripts
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Expression
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Orthologs
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for DDX51 gene

Disorders / Diseases
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External Searches for DDX51 gene

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DDX51 Gene

DEAD (Asp-Glu-Ala-Asp) box polypeptide 51

Aliasesfor DDX51 gene

Summariesfor DDX51 gene

Genomic Viewsfor DDX51 gene

Proteinsfor DDX51 gene

Protein Domains /Familiesfor DDX51 gene

Functionfor DDX51 gene

Pathways & Interactionsfor DDX51 gene

Drugs & Compoundsfor DDX51 gene

Transcriptsfor DDX51 gene

Expression for DDX51 gene

Orthologsfor DDX51 gene

Paralogsfor DDX51 gene

Genomic Variantsfor DDX51 gene

Disorders / Diseasesfor DDX51 gene

Publicationsfor DDX51 gene

External Searches for DDX51 gene

Genome Databases showing DDX51 gene

Other Databases showing DDX51 gene

Specialized Databases showing DDX51 gene

Intellectual Propertyfor DDX51 gene

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Aliases
for DDX51 gene

Summaries
for DDX51 gene

Genomic Views
for DDX51 gene

Proteins
for DDX51 gene

Protein Domains /
Families
for DDX51 gene

Function
for DDX51 gene

Pathways & Interactions
for DDX51 gene

Drugs & Compounds
for DDX51 gene

Transcripts
for DDX51 gene

Expression
for DDX51 gene

Orthologs
for DDX51 gene

Paralogs
for DDX51 gene

Genomic Variants
for DDX51 gene

Disorders / Diseases
for DDX51 gene

Publications
for DDX51 gene

Intellectual Property
for DDX51 gene

Products
for DDX51 gene