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DDX50 Gene

protein-coding   GIFtS: 53
GCID: GC10P070661

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50

  Search for DDX50
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 501 2     gu-beta2
Nucleolar Protein Gu22 3     Malignant Cell Derived RNA Helicase2
DEAD Box Protein 502 3     mcdrh2
GUB2 5     RNA Helicase II/Gu Beta2
GU22     EC 3.6.4.133
RH-II/GuB2     Gu-beta3
ATP-Dependent RNA Helicase DDX502     EC 3.6.18

External Ids:    HGNC: 179061   Entrez Gene: 790092   Ensembl: ENSG000001076257   OMIM: 6103735   UniProtKB: Q9BQ393   

Export aliases for DDX50 gene to outside databases

Previous GC identifers: GC10P070553 GC10P070005 GC10P070331 GC10P064662


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DDX50 Gene:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They
are implicated in a number of cellular processes involving alteration of RNA secondary structure such as
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their
distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis,
spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in
ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic
structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene
duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene
generates multiple transcript variants, but the full length nature of all the other variants but one has not been
defined. (provided by RefSeq, Jul 2008)

GeneCards Summary for DDX50 Gene:
DDX50 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 50) is a protein-coding gene. GO annotations related to this gene include RNA binding and ATP-dependent helicase activity. An important paralog of this gene is DDX21.

Gene Wiki entry for DDX50 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX50 gene promoter:
         HOXA9   HOXA9B   MAZR   p53   POU3F2   MEF-2A   N-Myc   aMEF-2   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX50 promoter sequence
   Search Chromatin IP Primers for DDX50

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX50


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.2

DDX50 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX50 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P070661:  view genomic region     (about GC identifiers)

Start:
70,661,034 bp from pter      End:
70,706,603 bp from pter
Size:
45,570 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DDX50_HUMAN, Q9BQ39 (See protein sequence)
Recommended Name: ATP-dependent RNA helicase DDX50  
Size: 737 amino acids; 82565 Da
Subunit: Interacts with C1QBP
1 PDB 3D structure from and Proteopedia for DDX50:
2E29 (3D)    
Secondary accessions: Q5VX37 Q8WV76 Q9BWI8

Explore the universe of human proteins at neXtProt for DDX50: NX_Q9BQ39

Explore proteomics data for DDX50 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for DDX50 (Q9BQ39) (see all 14)
     GRTGRAG  LAPTREL  VGTPGRI  APTRELA 


    See DDX50 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076950.1  
    ENSEMBL proteins: 
     ENSP00000362687   ENSP00000474785   ENSP00000474314  

    DDX50 Human Recombinant Protein Products:

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    Novus Biologicals DDX50 Protein
    Novus Biologicals DDX50 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DDX50

     
    Search eBioscience for Proteins for DDX50 

    DDX50 Antibody Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    Selected InterPro protein domains (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR012562 GUCT
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q9BQ39

    ProtoNet protein and cluster: Q9BQ39

    1 Blocks protein domain: IPB012562 GUCT

    UniProtKB/Swiss-Prot: DDX50_HUMAN, Q9BQ39
    Similarity: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with DDX50           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX50_HUMAN, Q9BQ39
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding ----
    GO:0003723RNA binding ----
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with DDX50           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Ddx50 (no phenotypes)

    Find genes that share phenotypes with DDX50           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DDX50
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    miRNA
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    miRTarBase miRNAs that target DDX50:
    hsa-mir-124-3p (MIRT023132), hsa-mir-30a-5p (MIRT028640), hsa-mir-215-5p (MIRT024678), hsa-mir-125b-5p (MIRT046014), hsa-mir-192-5p (MIRT026875), hsa-mir-1 (MIRT024089)

    Block miRNA regulation of human, mouse, rat DDX50 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DDX50 (see all 11):
    hsa-miR-4311 hsa-miR-578 hsa-miR-342-3p hsa-miR-548m hsa-miR-493* hsa-miR-518a-5p hsa-miR-1243 hsa-miR-3165
    SwitchGear 3'UTR luciferase reporter plasmidDDX50 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DDX50

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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DDX50 (NM_024045)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX50
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX50

    Cell Line
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX50


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DDX50_HUMAN, Q9BQ39: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane4
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005730nucleolus IDA--
    GO:0005886plasma membrane IDA--

    Find genes that share ontologies with DDX50           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX50
    Interactions:

        Search GeneGlobe Interaction Network for DDX50

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DDX50 (Q9BQ392, 3 ENSP000003626874) via UniProtKB, MINT, STRING, and/or I2D (see all 206)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MED19A0JLT23, ENSP000003373404STRING: ENSP00000337340 I2D: score=1 
    SRRM2Q9UQ353, ENSP000003017404I2D: score=1 STRING: ENSP00000301740
    STAU1O957933, ENSP000003609224I2D: score=1 STRING: ENSP00000360922
    UBCP0CG482, ENSP000003448184MINT-6488791 STRING: ENSP00000344818
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX50



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DDX50 gene: 
    NM_024045.1  

    Unigene Cluster for DDX50:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
    Hs.522984  [show with all ESTs]
    Unigene Representative Sequence: BC000272
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373585(uc001jot.3 uc001jou.3) ENST00000483593 ENST00000471475
    ENST00000460470 ENST00000466265
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DDX50 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DDX50 (see all 11):
    hsa-miR-4311 hsa-miR-578 hsa-miR-342-3p hsa-miR-548m hsa-miR-493* hsa-miR-518a-5p hsa-miR-1243 hsa-miR-3165
    SwitchGear 3'UTR luciferase reporter plasmidDDX50 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for DDX50
    Predesigned siRNA for gene silencing in human, mouse, rat DDX50
    Clone
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    GenScript: all cDNA clones in your preferred vector: DDX50 (NM_024045)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX50
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX50
    Primer
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    OriGene qPCR primer pairs and template standards for DDX50
    OriGene qSTAR qPCR primer pairs in human, mouse for DDX50
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DDX50
      QuantiTect SYBR Green Assays in human, mouse, rat DDX50
      QuantiFast Probe-based Assays in human, mouse, rat DDX50

    Additional mRNA sequence: 

    AB051075.1 AF334103.1 AK223297.1 AK293577.1 AK301431.1 AL137423.1 BC000210.1 BC000272.1 
    BC014263.2 BC018637.2 

    12 DOTS entries:

    DT.100792166  DT.212281  DT.100769536  DT.99972890  DT.101966618  DT.92437423  DT.100792163  DT.92437425 
    DT.95359183  DT.121226078  DT.91649131  DT.95117151 

    Selected AceView cDNA sequences (see all 199):

    CA434104 BF058887 AI859306 AI688898 CR620490 BQ935244 AI540598 BC000272 
    BM465158 AI707720 BM476752 BX507235 BM791077 BQ949618 CA432930 BM786121 
    BX333581 CR618753 BG055710 AI567697 BF513490 AF334103 CF994796 BC000210 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DDX50    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                                                                                                        
    SP2:              -                                                                                                         
    SP3:                                                                                                                        
    SP4:                                                                                                                        
    SP5:              -     -                                                                                                   


    ECgene alternative splicing isoforms for DDX50

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX50 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACATTATCC
    DDX50 Expression
    About this image

    DDX50 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX50 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.522984
        Custom PCR Arrays for DDX50
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX50

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX50 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx501 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 501, 5 92.74(n)1
    96(a)1
      10 (32.44 cM)5
    942131  NM_053183.21  NP_444413.11 
     626160235 
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    63(a)
    61(a)
    many ↔ many
    many ↔ many
    6(10383543-10389962)
    6(10368934-10382418)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    52(a)
    1 → many
    GL343215.1(1871445-1926394)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.60152 Transcribed sequence with weak similarity to protein more 73.44(n)    142005932 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx216
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
    49(a)
    1 → many
    13(174494-184799) ENSDARG00000063626
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRH4(YGL064C)4 Mitochondrial ATP-dependent RNA helicase of the DEAD-box more   --   7(383208-381523) 852816  NP_011451.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons emb11381 emb1138 49.73(n)
    41.68(a)
      832713  NM_001036866.3  NP_001031943.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g08277001 Os03g0827700 51.26(n)
    44.67(a)
      4334649  NM_001058308.1  NP_001051773.1 


    ENSEMBL Gene Tree for DDX50 (if available)
    TreeFam Gene Tree for DDX50 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX50 gene
    DDX212  
    6 SIMAP similar genes for DDX50 using alignment to 3 protein entries:     DDX50_HUMAN (see all proteins):
    DKFZp761E0323    mcdrh    DDX21    DDX54    EIF4A2    DDX47

    Find genes that share paralogs with DDX50           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for DDX50
    PGOHUM00000240615 PGOHUM00000237825


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX50 (see all 1095)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1825155441,2
    --70659075(+) AAAATC/GATATC 1 -- us2k10--------
    rs1407775351,2
    --70659173(+) CCCTTC/TCCATC 1 -- us2k10--------
    rs1169481571,2
    C,F--70659242(+) TCTGTA/GGTGTT 1 -- us2k11Minor allele frequency- G:0.02NA 120
    rs1872247831,2
    C--70659336(+) TTTTTC/TTCAGG 1 -- us2k10--------
    rs1497044201,2
    C--70659342(+) TCAGGC/TCCGCT 1 -- us2k10--------
    rs1455074411,2
    C--70659388(+) GTGCTC/TAGGAG 1 -- us2k10--------
    rs1402527111,2
    --70659398(+) GCTCAA/GCTTTT 1 -- us2k10--------
    rs1452161151,2
    --70659473(+) CGTGCA/GGCATT 1 -- us2k10--------
    rs780374911,2
    C--70659659(+) TCTCCG/ATCATC 1 -- us2k11Minor allele frequency- A:0.01EA 120
    rs782757521,2
    F--70659689(+) TGTTTC/GTAAGT 1 -- us2k11Minor allele frequency- G:0.02WA 118

    HapMap Linkage Disequilibrium report for DDX50 (70661034 - 70706603 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for DDX50:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2579637CNV Insertion19546169
    nsv519999CNV Loss19592680
    nsv831907CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610373    OMIM disorders: --


    Find genes that share disorders with DDX50           About GenesLikeMe

    Genetic Association Database (GAD): DDX50

    Export disorders for DDX50 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX50 gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with DDX50)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic structure of newly identified paralogue of RNA helicase II/Gu: detection of pseudogenes and multiple alternatively spliced mRNAs. (PubMed id 11891046)1, 2, 3, 9 Valdez B.C.... Sequitin A.M. (Gene 2002)
    2. Solution structure of the GUCT domain from human RNA helicase II/Gu beta reveals the RRM fold, but implausible RNA interactions. (PubMed id 18615715)1, 2, 9 Ohnishi S.... Yokoyama S. (Proteins 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PubMed id 22751105)1 Chu L....Tomasson M.H. (J. Clin. Invest. 2012)
    9. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    10. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79009 HGNC: 17906 AceView: DDX50 Ensembl:ENSG00000107625 euGenes: HUgn79009
    ECgene: DDX50 H-InvDB: DDX50

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX50 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DDX50 gene:
    Search GeneIP for patents involving DDX50

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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