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DDX49 Gene

protein-coding   GIFtS: 54
GCID: GC19P019030

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 49

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 491 2
DEAD Box Protein 492 3
R27090_22
Probable ATP-Dependent RNA Helicase DDX492
EC 3.6.4.133
EC 3.6.18

External Ids:    HGNC: 186841   Entrez Gene: 545552   Ensembl: ENSG000001056717   UniProtKB: Q9Y6V73   

Export aliases for DDX49 gene to outside databases

Previous GC identifers: GC19P018875 GC19P018891 GC19P018594


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DDX49 Gene:
DDX49 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 49) is a protein-coding gene. Diseases associated with DDX49 include malaria. GO annotations related to this gene include RNA binding and ATP-dependent helicase activity.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX49 gene promoter:
         AhR   AML1a   MyoD   Lmo2   CUTL1   Nkx2-5   c-Ets-1   HEN1   FOXJ2   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX49 promoter sequence
   Search Chromatin IP Primers for DDX49

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX49


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p12   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p12

DDX49 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX49 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P019030:  view genomic region     (about GC identifiers)

Start:
19,030,484 bp from pter      End:
19,039,442 bp from pter
Size:
8,959 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for DDX49

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DDX49_HUMAN, Q9Y6V7 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX49  
Size: 483 amino acids; 54226 Da
Secondary accessions: Q53FJ1

Explore the universe of human proteins at neXtProt for DDX49: NX_Q9Y6V7

Explore proteomics data for DDX49 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys23
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for DDX49 (Q9Y6V7) (see all 17)
     TDVASRG  RVGRTAR  TPTRELA  YIHRVGR 


    See DDX49 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061943.2  
    ENSEMBL proteins: 
     ENSP00000247003   ENSP00000470440   ENSP00000471292   ENSP00000472289   ENSP00000472084  
     ENSP00000469086   ENSP00000395377  

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    Cloud-Clone Corp. Proteins for DDX49

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    Selected InterPro protein domains (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q9Y6V7

    ProtoNet protein and cluster: Q9Y6V7

    1 Blocks protein domain: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX49_HUMAN, Q9Y6V7
    Similarity: Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    DDX49 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX49_HUMAN, Q9Y6V7
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    DDX49 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DDX49:
     Increased gamma-H2AX phosphory  Nuclear pre-40S maturation def 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DDX49
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DDX49
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DDX49

    miRNA
    Products:
        
    miRTarBase miRNAs that target DDX49:
    hsa-let-7b-5p (MIRT032226), hsa-mir-25-3p (MIRT050235), hsa-mir-3177-3p (MIRT052803)

    Block miRNA regulation of human, mouse, rat DDX49 using miScript Target Protectors
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    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DDX49

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    GenScript: all cDNA clones in your preferred vector: DDX49 (NM_019070)
    Sino Biological Human cDNA Clone for DDX49
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX49

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    Browse ESI BIO Cell Lines and PureStem Progenitors for DDX49 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX49


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX49
    Interactions:

        Search GeneGlobe Interaction Network for DDX49

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DDX49 (Q9Y6V73 ENSP000002470034) via UniProtKB, MINT, STRING, and/or I2D (see all 188)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX49



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DDX49 gene: 
    NM_019070.4  

    Unigene Cluster for DDX49:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
    Hs.143187  [show with all ESTs]
    Unigene Representative Sequence: BC000979
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000247003(uc002nkq.2 uc002nks.2) ENST00000599981 ENST00000599373
    ENST00000594021 ENST00000595858 ENST00000593361 ENST00000598972 ENST00000602113
    ENST00000601803 ENST00000599156 ENST00000601772 ENST00000598277 ENST00000596502
    ENST00000438170(uc002nkr.2 uc002nkt.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DDX49 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate DDX49
    SwitchGear 3'UTR luciferase reporter plasmidDDX49 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for DDX49
    Predesigned siRNA for gene silencing in human, mouse, rat DDX49
    Clone
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    OriGene clones in human, mouse for DDX49 (see all 7)
    OriGene ORF clones in mouse, rat for DDX49
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DDX49 (NM_019070)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX49
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX49
    Primer
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    OriGene qPCR primer pairs and template standards for DDX49
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DDX49
      QuantiTect SYBR Green Assays in human, mouse, rat DDX49
      QuantiFast Probe-based Assays in human, mouse, rat DDX49

    Additional mRNA sequence: 

    AK001294.1 AK223294.1 AK291916.1 BC000979.3 BC002674.2 BX647408.1 NR_033677.1 

    15 DOTS entries:

    DT.100809950  DT.100809952  DT.446105  DT.100809954  DT.100809955  DT.95155786  DT.75149763  DT.100809937 
    DT.40132185  DT.95155795  DT.100809943  DT.100809945  DT.100809956  DT.121497945  DT.95119200 

    Selected AceView cDNA sequences (see all 334):

    BM465803 BG995958 CR609065 BM854148 BE302790 CR605206 BI833174 BI916804 
    BQ425347 CR605744 BG825164 BU183994 BU160301 BI489915 BQ215667 BP374196 
    BI756099 AU125015 BQ226498 BQ441800 BI752077 CR612560 BQ063733 CR623471 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DDX49 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
    SP1:                                                                                                                                                
    SP2:                                      -                                                                                                         
    SP3:                                      -     -                                                                                                   
    SP4:                          -           -     -                                                                                                   
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for DDX49

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX49 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCGGGAGGT
    DDX49 Expression
    About this image


    DDX49 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Bone (Muscoskeletal System)
             Bone Marrow
    DDX49 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX49 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.143187
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX49

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX49 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx491 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 491, 5 85.4(n)1
    92.52(a)1
      8 (34.15 cM)5
    2343741  NM_001024922.21  NP_001020093.21 
     702928665 
    chicken
    (Gallus gallus)
    Aves DDX491 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 76.66(n)
    84.89(a)
      420116  NM_001030938.1  NP_001026109.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia ddx49-A-prov2 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 74.9(n)    BC049396.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx492 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 74.94(n)   386632  BC047834.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dbp45A1 DEAD box protein 45A 55.33(n)
    51.03(a)
      35917  NM_057579.4  NP_476927.1 
    worm
    (Caenorhabditis elegans)
    Secernentea H20J04.41 H20J04.4 51.45(n)
    51.23(a)
      186756  NM_001047324.2  NP_001040789.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DBP8(YHR169W)4
    DBP81
    ATPase, putative RNA helicase of the DEAD-box family; more4
    DBP81
    50.57(n)1
    49.76(a)1
      8(442181-443476)4
    8565741, 4  NP_012039.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RH361 RH36 51.83(n)
    47.92(a)
      838197  NM_101494.1  NP_173078.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g06335001 Os07g0633500 52.94(n)
    50.98(a)
      4344011  NM_001066909.1  NP_001060374.1 


    ENSEMBL Gene Tree for DDX49 (if available)
    TreeFam Gene Tree for DDX49 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX49 gene
    Selected SIMAP similar genes for DDX49 using alignment to 6 protein entries:     DDX49_HUMAN (see all proteins) (see all similar genes):
    DKFZp564G1016    DDX47    E4-DBP    DDX27    DDX54    DDX6
    DDX56    EIF4A1    DDX42    DDX39B    DDX17    DDX41
    DDX5    DDX18    DDX46    EIF4A3    EIF4A2    DDX39A

    DDX49 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX49 (see all 267)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs753577551,2
    C,F--19032224(+) CACAGG/TTTTGG 2 -- int14Minor allele frequency- T:0.05NA WA EA 360
    rs81059811,2
    C,A--19032319(+) CACAAT/CGGCCT 2 -- int12Minor allele frequency- C:0.00NA 4
    rs1863511931,2
    --19032375(+) AGGAGC/TCTGGG 2 -- int10--------
    rs455944321,2
    F--19032410(+) GGAGAG/AGGGAA 2 -- int11Minor allele frequency- A:0.02NA 120
    rs1997014291,2
    C--19032459(+) GCCCCC/TTCACA 2 -- int10--------
    rs22319961,2
    C,F,H--19032561(+) GGGTAC/TGGGAG 2 -- int19Minor allele frequency- T:0.01NS EA NA WA CSA EU 1741
    rs81063631,2
    A--19032618(+) CCACCC/TGCCCA 2 -- int10--------
    rs22319971,2
    C,F,A,H--19032637(+) TCTCAC/TGCTCT 2 -- int127Minor allele frequency- T:0.40EA NA NS WA CSA EU 4798
    rs1384119641,2
    C--19032640(+) CATGC-/TCTG  
            
    TCCCC
    2 -- int10--------
    rs1807455261,2
    C--19032647(+) TGTCCA/CCCAGA 2 -- int10--------

    HapMap Linkage Disequilibrium report for DDX49 (19030484 - 19039442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for DDX49:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833777CNV Loss17160897
    nsv470132CNV Loss18288195
    dgv3786n71CNV Loss21882294
    dgv3787n71CNV Loss21882294
    nsv833778CNV Loss17160897
    dgv3788n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for DDX49:    
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    malaria


    DDX49 for disorders           About GeneDecksing


    Export disorders for DDX49 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX49 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with DDX49)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    4. Human CCAAT/enhancer-binding protein I^ interacts with chromatin remodeling complexes of the imitation switch subfamily. (PubMed id 22242598)1 Steinberg X.P....GutiAcrrez J.L. (Biochemistry 2012)
    5. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    10. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54555 HGNC: 18684 AceView: DDX49 Ensembl:ENSG00000105671 euGenes: HUgn54555
    ECgene: DDX49 H-InvDB: DDX49

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX49 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DDX49 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DDX49 gene:
    Search GeneIP for patents involving DDX49

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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