Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX47 Gene

protein-coding   GIFtS: 48
GCID: GC12P012966

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47

 Explore 2 diseases affiliated with
DDX47 via our new
 Human Malady Compendium 
Biological research products
for DDX47
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 471 2     MSTP1622
HQ02561 2     DEAD Box Polypeptide 472
RRP31 2     E4-DEAD Box Protein2
DEAD Box Protein 472 3     Probable ATP-Dependent RNA Helicase DDX472
DKFZp564O1761     EC 3.6.4.133
FLJ300121     EC 3.6.18
E4-DBP2     

External Ids:    HGNC: 186821   Entrez Gene: 512022   Ensembl: ENSG000002137827   UniProtKB: Q9H0S43   

Export aliases for DDX47 gene to outside databases

Previous GC identifers: GC12P012866 GC12P012857 GC12P012771


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX47:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving
alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and
ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to
be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can
shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced
transcript variants encoding distinct isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DDX47_HUMAN, Q9H0S4
Function: Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA
precursors

Gene Wiki entry for DDX47


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX47 gene promoter:
         COUP-TF1   TBP   AML1a   COUP   HNF-4alpha2   HNF-4alpha1   HNF-1A   COUP-TF   HNF-1   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX47 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX47

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX47


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.1   Ensembl cytogenetic band:  12p13.1   HGNC cytogenetic band: 12p13.2

DDX47 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX47 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P012966:  view genomic region     (about GC identifiers)

Start:
12,966,250 bp from pter      End:
12,982,915 bp from pter
Size:
16,666 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DDX47_HUMAN, Q9H0S4 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX47  
Size: 455 amino acids; 50647 Da
Subunit: Interacts with EIF2C1 and EIF2C2. Interacts with GABARAP. Interacts with NOL8; the interaction is
RNA-dependent
Subcellular location: Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis
1 PDB 3D structure from and Proteopedia for DDX47:
3BER (3D)    
Secondary accessions: B3KXP4 G5E955 Q96GM0 Q96NV8 Q9UI98
Alternative splicing: 2 isoforms:  Q9H0S4-1   Q9H0S4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DDX47: NX_Q9H0S4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H0S4

  • 4/24 DME Specific Peptides for DDX47 (Q9H0S4) (see all 24)
     TDVASRG  RVGRTAR  TPTRELA  LFSATMT 

    DDX47 Protein expression data from MOPED and PaxDb:    About this image 
    DDX47 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_057439.2  NP_957518.1  

    ENSEMBL proteins: 
     ENSP00000319578   ENSP00000350698   ENSP00000444000  

    Human Recombinant Protein Products for DDX47: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: DDX47
    OriGene Protein Over-expression Lysate: DDX47
    OriGene Custom Protein Services for DDX47 
    GenScript Custom Purified and Recombinant Proteins Services for DDX47
    Novus Biologicals DDX47 Protein
    Novus Biologicals DDX47 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX47

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--

    DDX47 for ontologies           About GeneDecksing



    DDX47 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DDX47 
    GenScript Custom Superior Antibodies Services for DDX47
    Novus Biologicals DDX47 Antibodies
    Abcam antibodies for DDX47 
    Uscn Antibodies for DDX47
    ThermoFisher Antibodies for DDX47

    Assay Products for DDX47: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DDX47
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DDX47


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DDX47 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q9H0S4

    ProtoNet protein and cluster: Q9H0S4

    1 Blocks protein family: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX47_HUMAN, Q9H0S4
    Similarity: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX47_HUMAN, Q9H0S4
    Function: Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA
    precursors
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI15977068
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    DDX47 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DDX47 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): DDX47
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX47
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DDX47
    SwitchGear 3'UTR luciferase reporter plasmidDDX47 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX47 (see all 7)
    OriGene shRNA RFP: DDX47
    OriGene siRNA: DDX47
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX47
    Sirion Biotech Custom design and validation of potent shRNA sequences against DDX47 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DDX47
    Sirion Biotech Customized adenovirus for overexpression of DDX47 
    Sirion Biotech Customized adenovirus for potent knockdown of DDX47

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): DDX47 (NM_201224)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX47
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX47 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DDX47
    Search LifeMap BioReagents cell lines for DDX47
    Sirion Biotech Customized stable knockdown cell line services for DDX47 
    Sirion Biotech Customized inducible knockdown cell line services for DDX47
    Sirion Biotech Customized stable overexpressing cell line services for DDX47
    Sirion Biotech Customized inducible overexpressing cell line services for DDX47

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX47


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DDX47

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/671 Interacting proteins for DDX47 (Q9H0S41, 2, 3 ENSP000003506984) via UniProtKB, MINT, STRING, and/or I2D (see all 671)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SART3Q150202, 3, ENSP000002282844MINT-6488791 I2D: score=2 STRING: ENSP00000228284
    COPAP536212, 3MINT-7947479 MINT-6488791 I2D: score=1 
    CCT3P493682, 3MINT-7947479 I2D: score=1 
    CCT5P486432, 3MINT-7947479 I2D: score=1 
    DDX6P261962, 3MINT-7947479 I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IMP16963496
    GO:0006397mRNA processing IEA--
    GO:0006915apoptotic process IDA15977068
    GO:0008380RNA splicing IMP16963496

    DDX47 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX47
    Search CenterWatch for drugs/clinical trials and news about DDX47 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX47 gene (2 alternative transcripts): 
    NM_016355.3  NM_201224.1  

    Unigene Cluster for DDX47:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
    Hs.719938  [show with all ESTs]
    Unigene Representative Sequence: AL136666
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000541537(uc009zhw.1) ENST00000352940 ENST00000426619 ENST00000544032(uc010shn.1)
    ENST00000358007 ENST00000545038 ENST00000544497 ENST00000542123 ENST00000544400
    ENST00000542832 ENST00000392155 ENST00000535722

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): DDX47
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX47
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DDX47
    SwitchGear 3'UTR luciferase reporter plasmidDDX47 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX47 (see all 7)
    OriGene shRNA RFP: DDX47
    OriGene siRNA: DDX47
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX47
    Sirion Biotech Custom design and validation of potent shRNA sequences against DDX47 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): DDX47 (NM_201224)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX47
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX47 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX47
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDX47
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX47
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX47

    Additional cDNA sequence: 

    AF078843.1 AJ276704.1 AK054574.1 AK222940.1 AK225144.1 AK302536.1 AK310501.1 AL136666.1 
    BC009379.2 BC068009.1 EF036507.1 

    18 DOTS entries:

    DT.100713211  DT.91975799  DT.91904847  DT.100830332  DT.121189963  DT.100044598  DT.121189951  DT.100845397 
    DT.100845403  DT.95128467  DT.95260190  DT.100768470  DT.100845407  DT.121189969  DT.91837251  DT.95110168 
    DT.95238546  DT.97807892 

    24/515 AceView cDNA sequences (see all 515):

    NM_201224 AI635031 BE247726 AI817879 AW273482 BC068009 BQ771657 BE894889 
    AA909558 CA417453 AA609015 AF190165 AI816806 BM985292 BQ223267 AI049650 
    CB159622 AI459066 BM670498 AI371495 AA581169 CR609545 AA292641 BF724429 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX47 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCTGTAATT
    DDX47 Expression
    About this image

    DDX47 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Reproductive SystemMesonephrosMesonephric cellsReproductive System
    BoneMandibular ProcessBone
    Reproductive SystemMesonephrosReproductive System
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DDX47 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX47

    SOURCE GeneReport for Unigene cluster: Hs.719938
        SABiosciences Custom PCR Arrays for DDX47
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX47
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDX47
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX47
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX47
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX47

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX47 gene from 9/35 species (see all 35)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DDX471 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 79.75(n)
    92.84(a)
      417959  NM_001007853.1  NP_001007854.1 
    lizard
    (Anolis carolinensis)
    Reptilia DDX476
    --
    90(a)
    1 ↔ 1
    5(27575206-27588705)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.80062 Xenopus laevis transcribed sequence with weak similarity more 77.11(n)    BU913273.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.147252 Transcribed sequence with weak similarity to protein more 74.01(n)    BM036510.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG92531 CG9253 64.56(n)
    71.85(a)
      35379  NM_136246.2  NP_610090.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_T26G10.11 Protein T26G10.1 61.48(n)
    64.76(a)
      176321  NM_066668.5  NP_499069.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RRP3(YHR065C)4
    RRP31
    Protein involved in rRNA processing; required for maturation more4
    Rrp3p1
    57.9(n)1
    56.82(a)1
      8(229037-227532)4
    8564621, 4  NP_011932.21, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G609901 DEAD-box ATP-dependent RNA helicase 10 62.01(n)
    60.64(a)
      836220  NM_125492.4  NP_568931.1 
    rice
    (Oryza sativa)
    Liliopsida Os.54212 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 70.67(n)    AK067769.1 


    ENSEMBL Gene Tree for DDX47 (if available)
    TreeFam Gene Tree for DDX47 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX47 gene
    DDX492  
    18/35 SIMAP similar genes for DDX47 using alignment to 2 protein entries:     DDX47_HUMAN (see all proteins) (see all similar genes):
    MST162    E4-DBP    DKFZp564G1016    DDX49    DDX39B    DDX39A
    DDX54    DDX27    DDX42    EIF4A3    DDX31    EIF4A2
    DDX6    EIF4A1    DDX19A    DDX19L    DDX19B    DDX10

    DDX47 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/387 NCBI SNPs in DDX47 are shown (see all 387    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1460171891,2
    C--12964701(+) AGCTC-/ACTACTGC 2 -- us2k10--------
    rs123049601,2
    C--12964752(+) CCCCCT/CGAGTA 2 -- us2k12Minor allele frequency- C:0.25NA WA 4
    rs1825267341,2
    --12964917(+) CCACCA/GCGGCC 2 -- us2k10--------
    rs1871844891,2
    --12965067(+) TGGGCC/GTATAT 2 -- us2k10--------
    rs1920438011,2
    --12965181(+) TAACTA/GTGCAT 2 -- us2k10--------
    rs1851083601,2
    --12965247(+) TGCAAC/TGAGCA 2 -- us2k10--------
    rs71377351,2
    C,F,A--12965248(+) GCAACG/CAGCAC 2 -- us2k15Minor allele frequency- C:0.21NA WA 126
    rs1903540741,2
    --12965259(+) CCTGCA/GCAGTG 2 -- us2k10--------
    rs1491430581,2
    --12965290(+) ACAGGA/GGGGCA 2 -- us2k10--------
    rs1930949451,2
    --12965371(+) ACAGTC/TTTGGT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX47 (12966250 - 12982915 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DDX47: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX47
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX47

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DDX47 for disorders           About GeneDecksing

    2 diseases for DDX47:    About MalaCards
    metastasis efficiency    malaria


    Export disorders for DDX47 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX47 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with DDX47)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Proteomic and functional analysis of Argonaute-containing mRNA- protein complexes in human cells. (PubMed id 17932509)1, 2 Hoeck J.... Meister G. (2007)
    2. NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47. (PubMed id 16963496)1, 2 Sekiguchi T....Nishimoto T. (2006)
    3. GABAA receptor-associated protein (GABARAP) induces apoptosis by interacting with DEAD (Asp-Glu-Ala-Asp/His) box polypeptide 47 (DDX 47). (PubMed id 15977068)1, 2 Lee J.H....Chun T. (2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51202 HGNC: 18682 AceView: DDX47andDKFZP434F0318 Ensembl:ENSG00000213782 euGenes: HUgn51202
    ECgene: DDX47 H-InvDB: DDX47

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX47 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX47 gene:
    Search GeneIP for patents involving DDX47

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for DDX47  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX47   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX47  
     OriGene Protein Over-expression Lysate for DDX47   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for DDX47   OriGene 3'-UTR Clone for DDX47  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX47  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for DDX47   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DDX47   OriGene Custom Protein Services for DDX47  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DDX47
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX47
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX47
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX47
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX47
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX47
     GenScript Custom Purified and Recombinant Proteins Services for DDX47 GenScript cDNA clones with any tag delivered in your preferred vector for DDX47
     GenScript Custom Assay Services for DDX47 GenScript Custom Superior Antibodies Services for DDX47
     GenScript Custom overexpressing Cell Line Services for DDX47 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DDX47 promoter
     Search Chromatin IP Primers for DDX47
     RT2 qPCR Primer Assay in human, mouse, rat DDX47
     GNC Network for DDX47
     SABiosciences Custom PCR Arrays for DDX47
     Search Tocris compounds for DDX47
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     DDX47 antibodies
     DDX47 proteins
     DDX47 lysates
     Antibodies for DDX47
     See all of Abcam's Antibodies, Kits and Proteins for DDX47
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     DDX47 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for DDX47
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX47
     SwitchGear 3'UTR luciferase reporter plasmids for DDX47
     SwitchGear Promoter luciferase reporter plasmids for DDX47
     ThermoFisher Antibodies for DDX47
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX47
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DDX47
    Sirion Biotech Customized:
     stable knockdown cell line services for DDX47
     inducible knockdown cell line services for DDX47
     design and validation of potent shRNA sequences against DDX47
     adenovirus for potent knockdown of DDX47
     adenovirus for overexpression of DDX47
     stable overexpressing cell line services for DDX47
     inducible overexpressing cell line services for DDX47
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DDX47 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4