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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX46 Gene

protein-coding   GIFtS: 59
GCID: GC05P134094

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 461 2     Prp5-Like DEAD-Box Protein2
DEAD Box Protein 462 3     RNA Helicase2
PRP5 Homolog2 3     EC 3.6.4.133
PRPF52     KIAA08013
Prp52     EC 3.6.18
Probable ATP-Dependent RNA Helicase DDX462     

External Ids:    HGNC: 186811   Entrez Gene: 98792   Ensembl: ENSG000001458337   UniProtKB: Q7L0143   

Export aliases for DDX46 gene to outside databases

Previous GC identifers: GC05P134125 GC05P134170 GC05P134122 GC05P129280


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX46 Gene:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes
involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial
splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The
protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA
splicing. (provided by RefSeq, Jul 2008)

GeneCards Summary for DDX46 Gene: 
DDX46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46) is a protein-coding gene. Diseases associated with DDX46 include fibromyalgia, and among its related super-pathways are mRNA Splicing - Major Pathway. GO annotations related to this gene include RNA binding and ATP-dependent helicase activity. An important paralog of this gene is DDX21.

UniProtKB/Swiss-Prot: DDX46_HUMAN, Q7L014
Function: Plays an essential role in splicing, either prior to, or during splicing A complex formation

Gene Wiki entry for DDX46 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_034772.6  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX46 gene promoter:
         MEF-2A   AREB6   SRY   FOXF2   NCX/Ncx   FOXO3a   FOXO3   CUTL1   aMEF-2   FOXO3b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX46 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX46

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX46


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.1   Ensembl cytogenetic band:  5q31.1   HGNC cytogenetic band: 5q31.1

DDX46 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX46 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P134094:  view genomic region     (about GC identifiers)

Start:
134,094,461 bp from pter      End:
134,190,823 bp from pter
Size:
96,363 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DDX46_HUMAN, Q7L014 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX46  
Size: 1031 amino acids; 117362 Da
Subunit: Integral component of the 17S U2 snRNP
Subcellular location: Nucleus speckle. Nucleus, Cajal body. Note=Present in Cajal bodies (CBs) and nuclear
speckles
Sequence caution: Sequence=BAA34521.2; Type=Erroneous initiation;
Secondary accessions: O94894 Q96EI0 Q9Y658

Explore the universe of human proteins at neXtProt for DDX46: NX_Q7L014

Explore proteomics data for DDX46 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7L014

  • 4/38 DME Specific Peptides for DDX46 (Q7L014) (see all 38)
     DMGFEPQ  GRDLIGI  LKRGAEI  GRTGRAG 

    DDX46 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DDX46 Protein Expression
    REFSEQ proteins: NP_055644.2  
    ENSEMBL proteins: 
     ENSP00000427290   ENSP00000416534   ENSP00000346236   ENSP00000426767   ENSP00000425073  

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    Cloud-Clone Corp. Proteins for DDX46 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0015030Cajal body IEA--
    GO:0016607nuclear speck IEA--

    DDX46 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DDX: DEAD-boxes

    5/6 InterPro protein domains (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q7L014

    ProtoNet protein and cluster: Q7L014

    1 Blocks protein domain: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX46_HUMAN, Q7L014
    Similarity: Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    DDX46 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX46_HUMAN, Q7L014
    Function: Plays an essential role in splicing, either prior to, or during splicing A complex formation
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
         
    DDX46 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DDX46:
     Decreased viability  Synthetic lethal with Ras 

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    SwitchGear 3'UTR luciferase reporter plasmidDDX46 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DDX46 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    Spliceosome0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for DDX46):
        Spliceosome


    DDX46 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX46

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/607 Interacting proteins for DDX46 (Q7L0142, 3 ENSP000003462364) via UniProtKB, MINT, STRING, and/or I2D (see all 607)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SF3A2Q154282, 3, ENSP000002214944MINT-5205584 I2D: score=2 STRING: ENSP00000221494
    SF3B1O755332, 3, ENSP000003353214MINT-7945693 I2D: score=2 STRING: ENSP00000335321
    PSMD3O432422, 3MINT-7945693 I2D: score=3 
    HSP90AA1P079002, 3MINT-7945693 I2D: score=2 
    PRPF40AO754002, 3MINT-7945693 I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--

    DDX46 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX46

    Search CenterWatch for drugs/clinical trials and news about DDX46

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX46 gene: 
    NM_014829.2  

    Unigene Cluster for DDX46:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
    Hs.406549  [show with all ESTs]
    Unigene Representative Sequence: NM_014829
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507392(uc003kzv.1) ENST00000452510(uc003kzw.3) ENST00000354283
    ENST00000509255 ENST00000513987 ENST00000505592 ENST00000513592 ENST00000509178
    ENST00000503946 ENST00000507053 ENST00000506332
    miRNA
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    hsa-miR-30c hsa-miR-29c hsa-miR-29a hsa-miR-30d hsa-miR-3133 hsa-miR-570 hsa-miR-548g hsa-miR-30a
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX46

    Additional mRNA sequence: 

    AB018344.1 AK126011.1 AK291788.1 BC012304.2 BC030755.1 BC105598.1 BX647426.1 

    20 DOTS entries:

    DT.407632  DT.444054  DT.120848604  DT.100782917  DT.95131159  DT.308835  DT.101982008  DT.86842368 
    DT.100832029  DT.100782916  DT.92441725  DT.95298846  DT.120848607  DT.120848608  DT.95184747  DT.98083357 
    DT.102824216  DT.120848583  DT.86852441  DT.92443395 

    24/243 AceView cDNA sequences (see all 243):

    AB018344 AI003503 BX284020 BM904150 CB122464 AI904633 BF665512 BK000565 
    AW160346 AA405884 BQ712549 AA629318 BI858161 AW377675 CD656438 AI373907 
    AA256994 AI431951 CD513754 BP369111 AK058058 NM_014829 AA405193 CK299499 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for DDX46 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^
    SP1:                                                  -                                         -                 -     -     -                                 
    SP2:                                                                                                                          -                                 
    SP3:                                                                                -           -                 -     -     -                                 
    SP4:                                                                                            -                       -     -                                 
    SP5:                                                                                                                                                            

    ExUns: 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26a · 26b
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:                                                      
    SP5:  -                                                   


    ECgene alternative splicing isoforms for DDX46

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX46 expression in normal human tissues (normalized intensities)      DDX46 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTCTGGAAC
    DDX46 Expression
    About this image


    DDX46 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             posterior singulate   
     
     Limb (Muscoskeletal System)
             Limb Bud
     
     Blood (Hematopoietic System)
             cmps   

    See DDX46 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX46

    SOURCE GeneReport for Unigene cluster: Hs.406549
        SABiosciences Custom PCR Arrays for DDX46
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX46 gene from 10/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx461 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 461, 5 89.3(n)1
    98.93(a)1
      13 (30.06 cM)5
    2128801  NM_145975.31  NP_666087.31 
     556350275 
    chicken
    (Gallus gallus)
    Aves DDX461 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 82.33(n)
    93.68(a)
      416312  XM_414629.3  XP_414629.3 
    lizard
    (Anolis carolinensis)
    Reptilia DDX466
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
    92(a)
    1 ↔ 1
    GL343223.1(250644-280087)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.132422 Xenopus laevis transcribed sequence with moderate similarity more 79.45(n)    BQ732868.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.254912 Transcribed sequence with moderate similarity to protein more 76.86(n)    CK145674.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG62271 CG6227 56.29(n)
    60.46(a)
      32464  NM_132792.2  NP_573020.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F53H1.11 Protein F53H1.1 55.05(n)
    51.28(a)
      176943  NM_001038322.2  NP_001033411.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PRP5(YBR237W)4 RNA helicase in the DEAD-box family, necessary for more   --   2(691969-694518) 852539  NP_009796.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G209201 DEAD-box ATP-dependent RNA helicase 42 54.12(n)
    48.07(a)
      838685  NM_101945.3  NP_173516.1 
    rice
    (Oryza sativa)
    Liliopsida Os.246202 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 70.42(n)    NM_189070.1 


    ENSEMBL Gene Tree for DDX46 (if available)
    TreeFam Gene Tree for DDX46 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX46 gene
    DDX212  DDX502  DDX52  DDX172  DDX422  DDX432  DDX532  
    18/24 SIMAP similar genes for DDX46 using alignment to 6 protein entries:     DDX46_HUMAN (see all proteins) (see all similar genes):
    DKFZp686J01190    DDX5    DDX54    DDX17    DDX43    DKFZp547B159
    DDX59    DDX6    DDX42    DDX53    DDX39A    DDX3X
    DDX3Y    DDX39B    EIF4A2    EIF4A3    EIF4A1    DDX41

    DDX46 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1479 SNPs in DDX46 are shown (see all 1479)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1498345521,2
    --134092601(+) AGCCAC/TGGGGG 1 -- us2k10--------
    rs1904671131,2
    --134092626(+) AACTCA/TTCTTG 1 -- us2k10--------
    rs1439416541,2
    --134092679(+) GTTGAC/GGTAAA 1 -- us2k10--------
    rs1834174601,2
    C--134092749(+) GTGCAA/TATCTA 1 -- us2k10--------
    rs791323361,2
    F--134092792(+) TTTCCA/CTCATC 1 -- us2k10--------
    rs1162268621,2
    C,F--134092846(+) AAAATA/GTGAGC 1 -- us2k12Minor allele frequency- G:0.02WA EA 238
    rs1877933801,2
    --134092856(+) CCTTTC/GTCCAA 1 -- us2k10--------
    rs1431586411,2
    C--134093030(+) AAAATA/TAGCTG 1 -- us2k10--------
    rs1466690801,2
    C--134093270(+) ATAATA/GTTCTC 1 -- us2k10--------
    rs1919044381,2
    --134093334(+) AAGAAA/GCACTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX46 (134094461 - 134190823 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DDX46:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv512860CNV Insertion21212237
    nsv830493CNV Loss17160897
    nsv523937CNV Gain19592680
    nsv830494CNV Gain+Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for DDX46:    About MalaCards
    fibromyalgia    


    DDX46 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DDX46

    Export disorders for DDX46 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX46 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with DDX46)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (2008)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. (PubMed id 12234937)1, 2 Will C.L....Luhrmann R. (2002)
    5. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. (PubMed id 22412018)1 Roux K.J.... Burke B. (2012)
    8. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    9. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9879 HGNC: 18681 AceView: DDX46 Ensembl:ENSG00000145833 euGenes: HUgn9879
    ECgene: DDX46 Kegg: 9879 H-InvDB: DDX46

    (According to HUGE)
    About This Section
    HUGE: KIAA0801

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX46 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX46 gene:
    Search GeneIP for patents involving DDX46

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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