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DDX43 Gene

protein-coding   GIFtS: 50
GCID: GC06P074104

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 43

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 431 2     DEAD Box Protein HAGE2 3
Cancer/Testis Antigen 131 2 3     DEAD-Box Protein 432
HAGE2 3 5     Probable ATP-Dependent RNA Helicase DDX432
Helical Antigen2 3     EC 3.6.4.133
CT132 3     EC 3.6.18
DEAD Box Protein 432 3     

External Ids:    HGNC: 186771   Entrez Gene: 555102   Ensembl: ENSG000000800077   OMIM: 6062865   UniProtKB: Q9NXZ23   

Export aliases for DDX43 gene to outside databases

Previous GC identifers: GC06P074054 GC06P074100 GC06P074161 GC06P071302


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DDX43 Gene:
The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays
tumor-specific expression. (provided by RefSeq, Jul 2008)

GeneCards Summary for DDX43 Gene:
DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43) is a protein-coding gene. Diseases associated with DDX43 include chronic myeloid leukemia, and myelodysplastic syndromes. GO annotations related to this gene include RNA binding and ATP-dependent RNA helicase activity. An important paralog of this gene is DDX46.

Gene Wiki entry for DDX43 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX43 gene promoter:
         ER-alpha   AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX43 promoter sequence
   Search Chromatin IP Primers for DDX43

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX43


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q13   Ensembl cytogenetic band:  6q13   HGNC cytogenetic band: 6q13

DDX43 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX43 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P074104:  view genomic region     (about GC identifiers)

Start:
74,104,285 bp from pter      End:
74,127,292 bp from pter
Size:
23,008 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DDX43_HUMAN, Q9NXZ2 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX43  
Size: 648 amino acids; 72844 Da
Secondary accessions: Q6NXR1

Explore the universe of human proteins at neXtProt for DDX43: NX_Q9NXZ2

Explore proteomics data for DDX43 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for DDX43 (Q9NXZ2) (see all 11)
     TDLASRG  TPTRELA  GRTGRAG  DMGFEPQ 


    See DDX43 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061135.2  
    ENSEMBL proteins: 
     ENSP00000359361   ENSP00000441636  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    Selected InterPro protein domains (see all 8):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR004087 KH_dom
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif

    Graphical View of Domain Structure for InterPro Entry Q9NXZ2

    ProtoNet protein and cluster: Q9NXZ2

    2 Blocks protein domains:
    IPB000629 ATP-dependent helicase
    IPB004087 KH domain


    UniProtKB/Swiss-Prot: DDX43_HUMAN, Q9NXZ2
    Similarity: Belongs to the DEAD box helicase family
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain
    Similarity: Contains 1 KH domain


    DDX43 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX43_HUMAN, Q9NXZ2
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0004004ATP-dependent RNA helicase activity TAS10919659
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
         
    DDX43 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DDX43:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DDX43
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    7 qRT-PCR Assays for microRNAs that regulate DDX43:
    hsa-miR-3658 hsa-miR-186 hsa-miR-1236 hsa-miR-485-3p hsa-miR-3653 hsa-miR-3133 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidDDX43 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--

    DDX43 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX43
    Interactions:

        Search GeneGlobe Interaction Network for DDX43

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for DDX43 (ENSP000003593614) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPAENSP000003570484STRING: ENSP00000357048
    DHX15ENSP000003367414STRING: ENSP00000336741
    IBA57ENSP000003556724STRING: ENSP00000355672
    RBM15ENSP000003587994STRING: ENSP00000358799
    RBM15BENSP000003138904STRING: ENSP00000313890
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process TAS10919659

    DDX43 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX43



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DDX43 gene: 
    NM_018665.2  

    Unigene Cluster for DDX43:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
    Hs.125507  [show with all ESTs]
    Unigene Representative Sequence: NM_018665
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370336(uc011dyn.1 uc003pgw.3) ENST00000464221 ENST00000479773
    ENST00000539829
    miRNA
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    7 qRT-PCR Assays for microRNAs that regulate DDX43:
    hsa-miR-3658 hsa-miR-186 hsa-miR-1236 hsa-miR-485-3p hsa-miR-3653 hsa-miR-3133 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidDDX43 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DDX43
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    GenScript: all cDNA clones in your preferred vector: DDX43 (NM_018665)
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    Primer
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    OriGene qPCR primer pairs and template standards for DDX43
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat DDX43
      QuantiTect SYBR Green Assays in human, mouse, rat DDX43
      QuantiFast Probe-based Assays in human, mouse, rat DDX43

    Additional mRNA sequence: 

    AJ278110.1 AK303324.1 AK313686.1 AL136751.1 BC056879.1 BC066938.1 

    3 DOTS entries:

    DT.400485  DT.121355947  DT.121355885 

    Selected AceView cDNA sequences (see all 29):

    BC066938 AI521173 BC056879 BQ020439 BX281294 CB114540 BU171821 AI378017 
    AL043701 BV205400 BG772793 NM_018665 BV205399 BE144935 BX646425 BQ023352 
    AI637624 AI638049 AA948168 AW593728 AL136751 BG724057 AJ278110 BE907039 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DDX43    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                          -                                                                                                   
    SP2:                          -           -                                                                                       
    SP3:                                                                                                                              


    ECgene alternative splicing isoforms for DDX43

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX43 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DDX43 Expression
    About this image


    DDX43 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Gonad
             Secondary Oocyte Antral Follicle
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Secondary Oocyte Antral Follicle
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    DDX43 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX43 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.125507

    UniProtKB/Swiss-Prot: DDX43_HUMAN, Q9NXZ2
    Tissue specificity: Expressed in testis. Expressed in many tumors of various histological types at a level that is
    100-fold higher than the level observed in normal tissues except testis

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX43

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DDX43 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx431 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 431, 5 79.66(n)1
    77.64(a)1
      9 (43.65 cM)5
    1000486581  NM_001191044.11  NP_001177973.11 
     783957775 
    chicken
    (Gallus gallus)
    Aves DDX431 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 63.33(n)
    61.71(a)
      428637  XM_004940430.1  XP_004940487.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    58(a)
    1 → many
    GL343341.1(166536-195687)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ddx431 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 63.13(n)
    61.78(a)
      779928  NM_001079005.1  NP_001072473.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx436
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
    48(a)
    1 → many
    13(27556546-27577923) ENSDARG00000022614
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78781 CG7878 52.82(n)
    51.76(a)
      40959  NM_141510.3  NP_649767.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y54G11A.31 CELE_Y54G11A.3 48.88(n)
    45.57(a)
      175083  NM_064572.4  NP_496973.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DBP26
    Essential ATP-dependent RNA helicase of the DEAD-b...
    37(a)
    1 → many
    XIV(413639-416281) YNL112W


    ENSEMBL Gene Tree for DDX43 (if available)
    TreeFam Gene Tree for DDX43 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX43 gene
    DDX462  DDX52  DDX172  DDX422  DDX532  
    11 SIMAP similar genes for DDX43 using alignment to 2 protein entries:     DDX43_HUMAN (see all proteins):
    DDX53    DDX5    DDX17    DDX46    DKFZp686J01190    EIF4A2
    DDX23    DDX42    DDX41    DDX3Y    DDX3X

    DDX43 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for DDX43
    PGOHUM00000235363 PGOHUM00000232685 PGOHUM00000232903


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX43 (see all 582)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs94468961,2
    --74102459(+) aagcaA/Gttatt 1 -- us2k10--------
    rs1888852941,2
    --74102499(+) ACAGGC/TGCACA 1 -- us2k10--------
    rs93430411,2
    C,A,H--74102551(+) ggtttC/Taccat 1 -- us2k13Minor allele frequency- T:0.17NA WA 6
    rs93504961,2
    C,A,H--74102597(+) atccaC/Gccgcc 1 -- us2k15Minor allele frequency- G:0.00NA WA CSA 9
    rs122051471,2
    C,F--74102649(+) catccA/TgccAA 1 -- us2k13Minor allele frequency- T:0.04NA EA 242
    rs5264161,2
    C,F,A,H--74102745(+) ctcacG/Attccc 1 -- us2k110Minor allele frequency- A:0.32NA WA CSA EA 372
    rs1813634111,2
    --74102763(+) TGGGAC/TTACAG 1 -- us2k10--------
    rs1150334711,2
    F--74102957(+) CACCTC/TAGCCT 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1385620961,2
    C--74103007(+) CAGGG-/TTCTCA 1 -- us2k10--------
    rs1866460641,2
    --74103054(+) AAGAGA/GTCCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX43 (74104285 - 74127292 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for DDX43:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830693CNV Loss17160897
    nsv518515CNV Loss19592680
    nsv886158CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DDX43
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX43

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606286    OMIM disorders: --

    6 diseases for DDX43:    
    About MalaCards
    chronic myeloid leukemia    myelodysplastic syndromes    myeloid leukemia    sarcoma
    melanoma    leukemia


    DDX43 for disorders           About GeneDecksing


    Export disorders for DDX43 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX43 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with DDX43)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification on a human sarcoma of two new genes with tumor- specific expression. (PubMed id 10919659)1, 2, 3, 9 Martelange V.M.F.... Boon T. (Cancer Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    4. Aberrant hypomethylation of DDX43 promoter in myelodysplastic syndrome. (PubMed id 22563673)1 Chen Q....Li Y. (Br. J. Haematol. 2012)
    5. The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo. (PubMed id 22393060)1 Linley A.J....Regad T. (J. Biol. Chem. 2012)
    6. Gene expression of helicase antigen in patients with acute and chronic myeloid leukemia. (PubMed id 22040965)1 Chen Q....Xiao G.F. (Zhongguo Shi Yan Xue Ye Xue Za Zhi 2011)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers. (PubMed id 20058853)1 Mathieu M.G....McArdle S.E. (Cancer Immun. 2010)
    9. Epigenetic regulation of human cancer/testis antigen gene, HAGE, in chronic myeloid leukemia. (PubMed id 17296563)1 Roman-Gomez J....Torres A. (Haematologica 2007)
    10. HAGE, a cancer/testis antigen with potential for melanoma immunotherapy: identification of several MHC class I/II HAGE-derived immunogenic peptides. (PubMed id 17487488)1 Mathieu M.G....McArdle S.E. (Cancer Immunol. Immunother. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55510 HGNC: 18677 AceView: DDX43 Ensembl:ENSG00000080007 euGenes: HUgn55510
    ECgene: DDX43 H-InvDB: DDX43

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX43 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DDX43 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DDX43 gene:
    Search GeneIP for patents involving DDX43

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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