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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX41 Gene

protein-coding   GIFtS: 51
GCID: GC05M176938

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41

 Explore 24 diseases affiliated with
DDX41 via our new
 Human Malady Compendium 
Biological research products
for DDX41
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 411 2     DEAD-Box Protein Abstrakt2
ABS1 2 3 5     Probable ATP-Dependent RNA Helicase DDX412
DEAD Box Protein 412 3     Putative RNA Helicase2
DEAD Box Protein Abstrakt Homolog2 3     EC 3.6.4.133
MGC88281     EC 3.6.18
2900024F02Rik2     

External Ids:    HGNC: 186741   Entrez Gene: 514282   Ensembl: ENSG000001832587   OMIM: 6081705   UniProtKB: Q9UJV93   

Export aliases for DDX41 gene to outside databases

Previous GC identifers: GC05M176869 GC05M176919 GC05M176871 GC05M171859


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX41:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis,
and cellular growth and division. This gene encodes a member of this family. The function of this member has not been
determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene
expression. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DDX41_HUMAN, Q9UJV9
Function: Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved
in pre-mRNA splicing

Gene Wiki entry for DDX41


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX41 gene promoter:
         E2F-3a   AP-1   ATF-2   E2F-2   IRF-1   E2F   E2F-1   STAT3   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DDX41 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX41

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX41


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

DDX41 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX41 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M176938:  view genomic region     (about GC identifiers)

Start:
176,938,578 bp from pter      End:
176,944,470 bp from pter
Size:
5,893 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DDX41_HUMAN, Q9UJV9 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX41  
Size: 622 amino acids; 69838 Da
Subunit: Identified in the spliceosome C complex
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=CAE46035.1; Type=Miscellaneous discrepancy; Note=Intron retention;
1 PDB 3D structure from and Proteopedia for DDX41:
2P6N (3D)    
Secondary accessions: B2RDC8 Q96BK6 Q96K05 Q9NT96 Q9NW04

Explore the universe of human proteins at neXtProt for DDX41: NX_Q9UJV9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UJV9

  • 4/15 DME Specific Peptides for DDX41 (Q9UJV9) (see all 15)
     GNTGIAT  TPGRLMD  VATPGRL  IHGGKDQ 

    DDX41 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_057306.2  
    ENSEMBL proteins: 
     ENSP00000330349   ENSP00000422753   ENSP00000421460   ENSP00000425739   ENSP00000426330  
     ENSP00000427082  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX41

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0071013catalytic step 2 spliceosome IDA11991638


    DDX41 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DDX41


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DDX41 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C
     IPR001878 Znf_CCHC

    Graphical View of Domain Structure for InterPro Entry Q9UJV9

    ProtoNet protein and cluster: Q9UJV9

    2 Blocks protein families:
    IPB000629 ATP-dependent helicase
    IPB001878 C2HC-type zinc-finger signature


    UniProtKB/Swiss-Prot: DDX41_HUMAN, Q9UJV9
    Similarity: Belongs to the DEAD box helicase family. DDX41 subfamily
    Similarity: Contains 1 CCHC-type zinc finger
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DDX41_HUMAN, Q9UJV9
    Function: Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved
    in pre-mRNA splicing
    Catalytic activity: ATP + H(2)O = ADP + phosphate

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

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    hsa-miR-432
    SwitchGear 3'UTR luciferase reporter plasmidDDX41 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX41

    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003723RNA binding IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--


    DDX41 for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for DDX41:
     Cell cycle / mitosis defect  Cell division defect  Increased S DNA content, incre  Increased gamma-H2AX phosphory 
     Increased number of mitotic ce 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DDX41

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/760 Interacting proteins for DDX41 (Q9UJV92, 3 ENSP000003303494) via UniProtKB, MINT, STRING, and/or I2D (see all 760)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCNB1P146352, 3MINT-7945693 MINT-7947479 I2D: score=4 
    NKAPQ8N5F72, ENSP000003604644MINT-8337673 MINT-8331403 STRING: ENSP00000360464
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    USP36Q9P2753, ENSP000003105904I2D: score=2 STRING: ENSP00000310590
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IC11991638
    GO:0006396RNA processing TAS10607561
    GO:0006915apoptotic process TAS10607561
    GO:0007275multicellular organismal development TAS10607561
    GO:0035458cellular response to interferon-beta IEA--


    DDX41 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    DDX41 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX41
    1 Novoseek chemical compound relationship for DDX41 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 6.04 1 8065313 (1)

    Search CenterWatch for drugs/clinical trials and news about DDX41 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX41 gene: 
    NM_016222.2  

    Unigene Cluster for DDX41:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
    Hs.484288  [show with all ESTs]
    Unigene Representative Sequence: AK091545
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512334 ENST00000330503(uc003mhn.3) ENST00000507955(uc003mho.3)
    ENST00000505081(uc003mhq.1) ENST00000503078(uc003mhp.3) ENST00000507900
    ENST00000504807 ENST00000512027 ENST00000511040 ENST00000508279 ENST00000513562
    ENST00000512431 ENST00000504781 ENST00000509576 ENST00000506965 ENST00000515562
    ENST00000510171

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    hsa-miR-432
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF195417.1 AK001255.1 AK026117.1 AK027768.1 AK091545.1 AK091774.1 AK092585.1 AK222598.1 
    AK310525.1 AK315491.1 AL137455.1 BC015476.1 BC067902.1 BX641072.1 

    24/37 DOTS entries (see all 37):

    DT.100847188  DT.85101027  DT.120867314  DT.120867280  DT.100847193  DT.100847194  DT.97768327  DT.92057283 
    DT.120867293  DT.120867276  DT.120867306  DT.100847199  DT.120867223  DT.95094554  DT.100847198  DT.120867264 
    DT.120867238  DT.120867247  DT.100847181  DT.100847183  DT.100847202  DT.120867251  DT.120867283  DT.120867295 

    24/579 AceView cDNA sequences (see all 579):

    BQ670983 BM835743 BM772833 CF131225 BM767448 BM835673 BM753057 BX360478 
    CB153413 BQ679668 CF272274 BM773396 BQ063674 BM772003 BM771589 BQ954270 
    BM766105 BQ420424 CF132268 CA487331 BM772000 BQ643283 BF337946 BU172972 

    GeneLoc Exon Structure

    5/25 Alternative Splicing Database (ASD) splice patterns (SP) for DDX41 (see all 25)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d ^ 9a · 9b · 9c ^ 10a · 10b · 10c ·
    SP1:                    -           -     -                                   -           -     -                             -     -     -                     
    SP2:                    -                                                     -           -     -                             -     -     -                     
    SP3:                    -           -     -           -     -     -           -           -     -                             -     -     -                     
    SP4:                    -           -     -                                   -           -     -                 -     -     -     -     -                     
    SP5:                    -           -     -                                   -           -     -                             -     -                           

    ExUns: 10d ^ 11 ^ 12a · 12b · 12c · 12d · 12e ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                                  -                                                               
    SP2:                                                  -                                                               
    SP3:                                                                                                                  
    SP4:                                                                                                                  
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for DDX41

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX41 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GACTTCTGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DDX41 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX41

    SOURCE GeneReport for Unigene cluster: Hs.484288
        SABiosciences Custom PCR Arrays for DDX41
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX41

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX41 gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx411 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 411, 5 89.39(n)1
    98.87(a)1
      13 (30.06 cM)5
    729351  NM_134059.21  NP_598820.21 
     555304105 
    chicken
    (Gallus gallus)
    Aves LOC1008598101 probable ATP-dependent RNA helicase DDX41-like 84.24(n)
    96.58(a)
      100859810  XM_003643675.1  XP_003643723.1 
    lizard
    (Anolis carolinensis)
    Reptilia DDX416
    --
    90(a)
    1 ↔ 1
    2(145603016-145621319)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.245332 Xenopus laevis transcribed sequence with weak similarity more 76.94(n)    CB198425.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.122232 Transcribed sequence with weak similarity to protein more 81.07(n)    BQ617609.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta abs1 abstrakt 65.72(n)
    67.34(a)
      40530  NM_079496.3  NP_524220.1 
    worm
    (Caenorhabditis elegans)
    Secernentea sacy-11 Protein SACY-1 54.97(n)
    54.8(a)
      172413  NM_059561.3  NP_491962.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G333701 putative DEAD-box ATP-dependent RNA helicase 43 59.09(n)
    64.66(a)
      829474  NM_119491.1  NP_195063.1 
    rice
    (Oryza sativa)
    Liliopsida Os.269982 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 75.53(n)    AK060595.1 


    ENSEMBL Gene Tree for DDX41 (if available)
    TreeFam Gene Tree for DDX41 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX41 gene
    DDX12  DDX52  DDX172  DDX432  DDX532  
    18/26 SIMAP similar genes for DDX41 using alignment to 7 protein entries:     DDX41_HUMAN (see all proteins) (see all similar genes):
    DDX23    MST162    DDX56    DKFZp547B159    DDX54    DDX5
    DDX3X    EIF4A2    DDX3Y    DDX52    DDX59    DKFZp686J01190
    DDX17    DDX39B    DDX43    DDX18    BAT1    DDX47

    DDX41 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/42 NCBI SNPs in DDX41 are shown (see all 42    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs764888701,2
    F,--171858666(+) GTCAAC/TGGAAT 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs3373951,2
    C,--171859213(+) GCTGAG/ACTGAA 1 -- ut31 ese31Minor allele frequency- A:0.00NA 2
    rs789232961,2
    C,F,--171859236(+) TCCAGG/AGGGCT 1 -- ut311Minor allele frequency- A:0.04WA 118
    rs10548601,2
    C--171859313(-) GACTTC/TTGAGC 2 F syn1 ese32Minor allele frequency- T:0.06MN NA 186
    rs1123434901,2
    C--171859840(+) ACTCAC/G/TCACAC 1 -- spd11CSA 1
    rs1128395071,2
    C--171859914(+) TGTACA/TGCAGA 1 -- spa11Minor allele frequency- T:0.00CSA 1
    rs1837920081,2
    --176938207(+) CCTGAA/GGCAAG 3 -- us2k10--------
    rs1506152991,2
    --176938281(+) GGGCCA/TGAGAG 3 -- us2k10--------
    rs1399548821,2
    --176938319(+) GAATCC/GAAGCA 3 -- us2k10--------
    rs1864127481,2
    --176938338(+) TGGCCC/TGCCAA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX41 (176938578 - 176944470 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for DDX41
         1 CNV: 36374

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DDX41 for disorders           About GeneDecksing

    OMIM gene information: 608170    OMIM disorders: --

    20/24 diseases for DDX41 (see all 24):    About MalaCards
    spinal muscular atrophy    hypersensitivity reaction type ii disease    human immunodeficiency virus infectious disease    muscular atrophy
    gastrointestinal system disease    lupus nephritis    lyme disease    nephritis
    myeloid malignancy    embryonal carcinoma    tetanus    hepatitis c
    retinoblastoma    hepatitis b    vaccinia    cholera
    dermatitis    hepatitis    immunodeficiency    influenza

    2 Novoseek disease relationships for DDX41 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoblastoma 45.1 2 8834177 (1), 9694872 (1)
    tumors 0 1 9694872 (1)


    Export disorders for DDX41 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX41 gene, integrated from 9 sources (see all 89):
    (articles sorted by number of sources associating them with DDX41)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Developmental and cell biological functions of the Drosophila DEAD- box protein abstrakt. (PubMed id 10607561)1, 2, 3 Irion U. and Leptin M. (1999)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    6. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immun e response. (PubMed id 23142775)1 Parvatiyar K....Cheng G. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
    10. Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51428 HGNC: 18674 AceView: DDX41 Ensembl:ENSG00000183258 euGenes: HUgn51428
    ECgene: DDX41 H-InvDB: DDX41

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX41 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX41 gene:
    Search GeneIP for patents involving DDX41

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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