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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX31 Gene

protein-coding   GIFtS: 49
GCID: GC09M135468

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31 )
  Search for DDX31
in
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 Human Malady Compendium 
Biological research products
for DDX31    

Aliases
for DDX31 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 311 2     G2 Helicase2
PPP1R251 2     Helicain3
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 311 2     Probable ATP-Dependent RNA Helicase DDX312
DEAD Box Protein 312 3     Protein Phosphatase 1, Regulatory Subunit 252
FLJ136331     EC 3.6.4.133
FLJ145781     Helicain3
FLJ233491     EC 3.6.18
DEAD/DEXH Helicase DDX312     

External Ids:    HGNC: 167151   Entrez Gene: 647942   Ensembl: ENSG000001254857   UniProtKB: Q9H8H23   

Export aliases for DDX31 gene to outside databases

Previous GC identifers: GC09M126494 GC09M127026 GC09M128823 GC09M130745 GC09M132499 GC09M134458 GC09M104963


Summaries
for DDX31 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DDX31:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis,
and cellular growth and division. This gene encodes a member of this family. The function of this member has not been
determined. Alternative splicing of this gene generates 2 transcript variants. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DDX31_HUMAN, Q9H8H2
Function: Probable ATP-dependent RNA helicase (By similarity)

Gene Wiki entry for DDX31


Genomic Views
for DDX31 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_035014.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX31 gene promoter:
         RFX1   YY1   C/EBPalpha   E47   E2F   E2F-1   POU2F1   POU2F1a   Hand1   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DDX31 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX31

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13   Ensembl cytogenetic band:  9q34.13   HGNC cytogenetic band: 9q34.2

DDX31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX31 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M135468:  view genomic region     (about GC identifiers)

Start:
 135,468,384 bp from pter      End:
 135,545,788 bp from pter
Size:
 77,405 bases      Orientation:
 minus strand

Proteins
for DDX31 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DDX31_HUMAN, Q9H8H2 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX31  
Size: 851 amino acids; 94087 Da
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=AAQ14889.1; Type=Frameshift; Positions=816, 825; Sequence=AAQ14890.1; Type=Frameshift;
Positions=816; Sequence=BAB14644.1; Type=Erroneous initiation; Sequence=BAB15620.1; Type=Frameshift; Positions=141;
Sequence=CAH70532.1; Type=Erroneous gene model prediction; Sequence=CAI16565.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5K6N2 Q5K6N3 Q5K6N4 Q5VZJ4 Q5VZJ9 Q96E91 Q96NY2 Q96SX5 Q9H5K6
Alternative splicing: 4 isoforms:  Q9H8H2-1   Q9H8H2-2   Q9H8H2-3   Q9H8H2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DDX31: NX_Q9H8H2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H8H2

    • 4/12 DME Specific Peptides for DDX31 (Q9H8H2) (see all 12)
     LVPTREL  VPTRELA  AKSFGLR  DEADRIL 

    DDX31 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_073616.6  NP_619526.1  

    ENSEMBL proteins: 
     ENSP00000361232   ENSP00000361228   ENSP00000310539   ENSP00000361226   ENSP00000387730  
     ENSP00000442425  

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    OriGene Protein Over-expression Lysate (see all 2): DDX31
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    Novus Biologicals DDX31 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX31

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--


    DDX31 for ontologies           About GeneDecksing



    DDX31 Antibody Products: 
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    Uscn ELISAs and CLIAs for DDX31

    Protein Domains /
    Families
    for DDX31 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DDX31 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR025313 DUF4217
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q9H8H2

    ProtoNet protein and cluster: Q9H8H2

    1 Blocks protein family: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX31_HUMAN, Q9H8H2
    Similarity: Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Function
    for DDX31 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DDX31_HUMAN, Q9H8H2
    Function: Probable ATP-dependent RNA helicase (By similarity)
    Catalytic activity: ATP + H(2)O = ADP + phosphate

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX31
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX31 (see all 9):
    hsa-miR-221* hsa-miR-2355-5p hsa-miR-3150b-3p hsa-miR-3658 hsa-miR-765 hsa-miR-3653 hsa-miR-548b-3p hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmid: DDX31 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX31 (see all 7)
    OriGene shRNA RFP: DDX31
    OriGene siRNA: DDX31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX31

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DDX31

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX31 (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX31 

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    Search LifeMap BioReagents cell lines for DDX31

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--


    DDX31 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for DDX31:
     Decreased viability of wild-ty  G0/1 arrest  Increased G1 DNA content 


    Pathways & Interactions
    for DDX31 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX31

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    5/92 Interacting proteins for DDX31 (Q9H8H23 ENSP000003612324) via UniProtKB, MINT, STRING, and/or I2D (see all 92)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPF2Q9H7B23, ENSP000004023384I2D: score=4 STRING: ENSP00000402338
    NIP7Q9Y2213, ENSP000002549404I2D: score=2 STRING: ENSP00000254940
    BOP1Q141373, ENSP000003041514I2D: score=1 STRING: ENSP00000304151
    GTPBP4Q9BZE43, ENSP000003540404I2D: score=1 STRING: ENSP00000354040
    MED19A0JLT23, ENSP000003373404STRING: ENSP00000337340 I2D: score=1 
    About this table

    Drugs & Compounds
    for DDX31 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX31
    Search CenterWatch for drugs/clinical trials and news about DDX31 

    Transcripts
    for DDX31 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DDX31 gene (2 alternative transcripts): 
    NM_022779.7  NM_138620.1  

    Unigene Cluster for DDX31:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
    Hs.660767  [show with all ESTs]
    Unigene Representative Sequence: AF427339
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372159(uc004cbq.1) ENST00000372155 ENST00000310532(uc004cbr.1)
    ENST00000480876(uc004cbs.2) ENST00000482620 ENST00000372153(uc010mzu.1)
    ENST00000438527 ENST00000544003

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX31
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX31 (see all 9):
    hsa-miR-221* hsa-miR-2355-5p hsa-miR-3150b-3p hsa-miR-3658 hsa-miR-765 hsa-miR-3653 hsa-miR-548b-3p hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmid: DDX31 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX31 (see all 7)
    OriGene shRNA RFP: DDX31
    OriGene siRNA: DDX31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX31
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): DDX31 (NM_022779)
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    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDX31
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX31
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX31

    Additional cDNA sequence: 

    AF335567.1 AF335568.1 AF335569.1 AF427339.1 AK023695.1 AK027002.1 AK027484.1 AK225121.1 
    AK225350.1 AK302670.1 AK304715.1 BC012726.2 

    10 DOTS entries:

    DT.411298  DT.75111957  DT.101978566  DT.97841365  DT.91714402  DT.101963499  DT.91807563  DT.92002888 
    DT.92423844  DT.102827625 

    24/104 AceView cDNA sequences (see all 104):

    BE797061 AI214317 AA402462 AF427339 NM_022779 NM_138620 BU180734 BC012726 
    BX401058 AW474074 CD672604 AI703282 BE503800 BX331416 BU175522 AK023695 
    BQ229587 CR594429 AA928863 AA234394 AA234304 BM787297 AA570331 AI272273 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DDX31    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:              -                             -                 -                                   -                                                         
    SP2:              -                             -                                                                                                               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21 ^ 22
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for DDX31

    Expression
    for DDX31 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATTTTGTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DDX31 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DDX31 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX31

    SOURCE GeneReport for Unigene cluster: Hs.660767
        SABiosciences Custom PCR Arrays for DDX31
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    In Situ
    Assay Products:     
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    Orthologs
    for DDX31 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX31 gene from 7/33 species (see all 33)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves DDX311 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 70.61(n)
    68.09(a)    		   427759  XM_425332.3  XP_425332.3 
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.151622 Xenopus laevis transcribed sequence with weak similarity more 74.25(n)    BX850995.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.72842 Danio rerio cDNA clone IMAGE6794757, partial cds 72.25(n)    BC056735.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta BcDNA:GH028333
    CG86111    		 ATP dependent RNA helicase3
    CG86111    		 40(a)3
    46.42(n)1
    38.83(a)1    		   16A53
    327251  NM_132986.41  NP_573214.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes DBP7(YKR024C)4
    DBP71    		 Putative ATP-dependent RNA helicase of the DEAD-box more4
    Dbp7p1    		 45.32(n)1
    35.66(a)1    		   11(487372-485144)4
    8538941, 4  NP_012949.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G407001 DEAD-box ATP-dependent RNA helicase 17 48.78(n)
    43.41(a)    		   818665  NM_129632.1  NP_181602.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.195692 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.78(n)    AK060179.1 


    ENSEMBL Gene Tree for DDX31 (if available)
    TreeFam Gene Tree for DDX31 (if available) 

    Paralogs
    for DDX31 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for DDX31 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1289 NCBI SNPs in DDX31 are shown (see all 1289)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1405438711,2
    		--135469277(+) GCCCAC/TAGGTG 1 -- ds50010--------
    rs22365171,2
    		C,F,A,--135469394(+) AAACAC/TAATGC 1 -- ds50018Minor allele frequency- T:0.20NA WA CSA EA 367
    rs3065511,2
    		C,F,A,--135469410(+) CAGGGC/TGGGGT 1 -- ds5001 ese31Minor allele frequency- T:0.07WA 118
    rs1871662681,2
    		--135469490(+) GACAAA/GACAGG 1 -- ds50010--------
    rs735608471,2
    		C,--135469536(+) CTTTTG/TACTTC 1 -- ds50012Minor allele frequency- T:0.05WA 120
    rs1493229741,2
    		--135469765(+) AGTGAA/TAAATA 1 -- ut310--------
    rs3065501,2
    		C,F,A,H,--135469799(+) ATTCCA/GGTTTT 1 -- ut31 ese312Minor allele frequency- G:0.04NS EA NA WA 1388
    rs1905606711,2
    		--135469918(+) TGACGC/TGCAGG 1 -- ut310--------
    rs735608501,2
    		C,--135469944(+) ATCCCG/AGGGTG 1 -- ut312Minor allele frequency- A:0.05WA 120
    rs1445755501,2
    		--135470032(+) CCTTCC/TGTCGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DDX31 (135468384 - 135545788 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DDX31: --

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    Disorders / Diseases
    for DDX31 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for DDX31 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX31 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with DDX31)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    4. The human DDX and DHX gene families of putative RNA helicases. (PubMed id 12782131)1, 2 Abdelhaleem M.... Wain H. (2003)
    5. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Nucleolar proteome dynamics. (PubMed id 15635413)1 Andersen J.S....Mann M. (2005)

    External Searches for DDX31 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing DDX31 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64794 HGNC: 16715 AceView: DDX31 Ensembl:ENSG00000125485 euGenes: HUgn64794
    ECgene: DDX31 H-InvDB: DDX31

    Other Databases showing DDX31 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DDX31 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX31 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DDX31 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DDX31 gene:
    Search GeneIP for patents involving DDX31

    GeneCards and IP:
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