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DDX27 Gene

protein-coding   GIFtS: 51
GCID: GC20P047835

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 27

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 27)
  Search for DDX27
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 271 2     dJ686N3.12
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 271 2     Deficiency Of Ribosomal Subunits Protein 1 Homolog2
RHLP2 3     Probable ATP-Dependent RNA Helicase DDX272
DEAD Box Protein 272 3     RNA Helicase-Like Protein2
DRS12     EC 3.6.4.133
Drs1p2     EC 3.6.18
PP32412     

External Ids:    HGNC: 158371   Entrez Gene: 556612   Ensembl: ENSG000001242287   UniProtKB: Q96GQ73   

Export aliases for DDX27 gene to outside databases

Previous GC identifers: GC20P047564 GC20P048474 GC20P048521 GC20P047269 GC20P044584


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DDX27 Gene:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They
are implicated in a number of cellular processes involving alteration of RNA secondary structure such as
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their
distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis,
and cellular growth and division. This gene encodes a DEAD box protein, the function of which has not been
determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for DDX27 Gene:
DDX27 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 27) is a protein-coding gene. GO annotations related to this gene include ATP-dependent helicase activity and nucleic acid binding.

UniProtKB/Swiss-Prot: DDX27_HUMAN, Q96GQ7
Function: Probable ATP-dependent RNA helicase

Gene Wiki entry for DDX27 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX27 gene promoter:
         GR   c-Fos   AP-1   GR-beta   HNF-4alpha2   HNF-4alpha1   SEF-1 (1)   c-Jun   GR-alpha   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX27 promoter sequence
   Search Chromatin IP Primers for DDX27

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX27


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.13   Ensembl cytogenetic band:  20q13.13   HGNC cytogenetic band: 20q13.13

DDX27 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX27 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P047835:  view genomic region     (about GC identifiers)

Start:
47,835,832 bp from pter      End:
47,860,614 bp from pter
Size:
24,783 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DDX27_HUMAN, Q96GQ7 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX27  
Size: 796 amino acids; 89835 Da
Caution: It is uncertain whether Met-1 or Met-32 is the initiator
Sequence caution: Sequence=AAF28937.1; Type=Frameshift; Positions=Several; Sequence=AAF28937.1; Type=Miscellaneous
discrepancy; Note=Sequencing errors; Sequence=AAG22482.1; Type=Frameshift; Positions=208, 427, 434, 532;
Sequence=AAH16060.2; Type=Erroneous initiation; Sequence=BAA91284.1; Type=Erroneous initiation;
Sequence=BAB14343.1; Type=Erroneous initiation;
Secondary accessions: A0AVB6 B7ZLY1 Q5VXM7 Q8WYG4 Q969N7 Q96F57 Q96L97 Q9BWY9 Q9BXF0 Q9H990
Q9NWU3 Q9P0C2 Q9UGD6

Explore the universe of human proteins at neXtProt for DDX27: NX_Q96GQ7

Explore proteomics data for DDX27 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for DDX27 (Q96GQ7) (see all 16)
     RVGRTAR  LFSATMT  IQKACIP  DEADRML 


    See DDX27 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060365.7  
    ENSEMBL proteins: 
     ENSP00000360828  

    DDX27 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    Selected InterPro protein domains (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR027417 P-loop_NTPase
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q96GQ7

    ProtoNet protein and cluster: Q96GQ7

    1 Blocks protein domain: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX27_HUMAN, Q96GQ7
    Similarity: Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Find genes that share domains with DDX27           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX27_HUMAN, Q96GQ7
    Function: Probable ATP-dependent RNA helicase
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with DDX27           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for DDX27:
     Decreased viability of wild-ty 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ddx27):
     hematopoietic system  homeostasis/metabolism  immune system  mortality/aging 

    Find genes that share phenotypes with DDX27           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DDX27
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    hsa-mir-23b-3p (MIRT046324), hsa-mir-181a-5p (MIRT047314)

    Block miRNA regulation of human, mouse, rat DDX27 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate DDX27:
    hsa-miR-188-3p hsa-miR-617 hsa-miR-3202 hsa-miR-1260b hsa-miR-1260
    SwitchGear 3'UTR luciferase reporter plasmidDDX27 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX27

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX27


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DDX27_HUMAN, Q96GQ7: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with DDX27           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX27
    Interactions:

        Search GeneGlobe Interaction Network for DDX27

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DDX27 (Q96GQ72, 3 ENSP000003608284) via UniProtKB, MINT, STRING, and/or I2D (see all 160)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1R16AQ96I342, 3MINT-65186 I2D: score=5 
    PES1O005413, ENSP000003467254I2D: score=5 STRING: ENSP00000346725
    KIAA0020Q153973, ENSP000003809824I2D: score=3 STRING: ENSP00000380982
    YWHAGP619813, ENSP000003063304I2D: score=3 STRING: ENSP00000306330
    ARRB2P321213, ENSP000002692604I2D: score=2 STRING: ENSP00000269260
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX27



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DDX27 gene: 
    NM_017895.7  

    Unigene Cluster for DDX27:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
    Hs.65234  [show with all ESTs]
    Unigene Representative Sequence: AL832131
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371764(uc002xuh.3) ENST00000484427 ENST00000462328 ENST00000493252
    ENST00000471144
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate DDX27:
    hsa-miR-188-3p hsa-miR-617 hsa-miR-3202 hsa-miR-1260b hsa-miR-1260
    SwitchGear 3'UTR luciferase reporter plasmidDDX27 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DDX27
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    GenScript: all cDNA clones in your preferred vector: DDX27 (NM_017895)
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    Primer
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    OriGene qPCR primer pairs and template standards for DDX27
    OriGene qSTAR qPCR primer pairs in human, mouse for DDX27
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DDX27
      QuantiTect SYBR Green Assays in human, mouse, rat DDX27
      QuantiFast Probe-based Assays in human, mouse, rat DDX27

    Additional mRNA sequence: 

    AF336851.1 AK000603.1 AK022979.1 AK025891.1 AK127128.1 AK223116.1 AK300135.1 AL832131.1 
    AY044431.1 BC009304.1 BC011927.2 BC016060.1 BC104480.1 BC126287.1 BC130275.1 BC144125.1 
    EU718675.1 

    23 DOTS entries:

    DT.95264299  DT.111661  DT.120795507  DT.120795659  DT.100826370  DT.100826377  DT.101967845  DT.100030136 
    DT.120795670  DT.100826373  DT.97848016  DT.120795594  DT.40314857  DT.86853499  DT.92025660  DT.92456187 
    DT.95264296  DT.100826372  DT.120795693  DT.92456175  DT.100651867  DT.95264291  DT.97763707 

    Selected AceView cDNA sequences (see all 332):

    AA604815 BE742391 BC009304 BM825188 CB143241 BQ648934 AI861997 BX280434 
    AA377578 BG574985 AA505931 BQ901124 BQ654359 BC011927 BG388148 BU629675 
    AA393410 CF125461 AY044431 BP356413 BQ651484 BE727459 CB119280 CB124699 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX27 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGTCAATC
    DDX27 Expression
    About this image

    DDX27 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX27 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.65234
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX27

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX27 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx271 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 271, 5 87.94(n)1
    92.63(a)1
      2 (87.22 cM)5
    2288891  NM_153065.31  NP_694705.21 
     1670151935 
    chicken
    (Gallus gallus)
    Aves DDX271 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 74.73(n)
    80.59(a)
      419308  NM_001006293.1  NP_001006293.1 
    lizard
    (Anolis carolinensis)
    Reptilia DDX276
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
    76(a)
    1 ↔ 1
    GL343820.1(148826-160773)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.299762 Xenopus laevis transcribed sequence with weak similarity more 78.6(n)    BQ730622.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx272 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 76.8(n)   378844  CF417047.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rs11 , 3 ribosome biogenesis ATP dependent RNA
    helicase3
    Rs11
    51(a)
    (best of 2)3
    62.45(n)1
    63.4(a)1
      44B93
    440871  NM_143713.21  NP_651970.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y71G12B.81 , 3 Y71G12B.81 45(a)3
    55.36(n)1
    54.13(a)1
      I(1767943-1790006)3
    1717431  NM_058490.41  NP_490891.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DRS1(YLL008W)4 Nucleolar DEAD-box protein required for ribosome assembly more   --   12(131729-133987) 850652  NP_013093.1 
    rice
    (Oryza sativa)
    Liliopsida Os.276742 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.2(n)    AK073151.1 


    ENSEMBL Gene Tree for DDX27 (if available)
    TreeFam Gene Tree for DDX27 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX27 gene
    13 SIMAP similar genes for DDX27 using alignment to 3 protein entries:     DDX27_HUMAN (see all proteins):
    BAT1    DDX39A    DDX39B    DDX54    E4-DBP    EIF4A1
    MST162    DDX47    EIF4A2    DDX6    DDX49    EIF4A3
    DDX52

    Find genes that share paralogs with DDX27           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX27 (see all 726)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1433696481,2
    --47833923(+) TAGAAA/GGGTTA 1 -- us2k10--------
    rs1496823191,2
    C--47833931(+) TAGTT-/TGA   
       AGCTG
    TGAAG
    1 -- us2k10--------
    rs1177948231,2
    C,F--47834081(+) GTATAT/CCCTTC 1 -- us2k11Minor allele frequency- C:0.10EA 120
    rs736240691,2
    C--47834089(+) TTCCT-/AACA  
            
    GTGTC
    1 -- us2k10--------
    rs60954651,2
    C,F,H--47834199(+) GTTTTT/GTTTTT 1 -- us2k1 trp37Minor allele frequency- G:0.09NS EA NA WA 536
    rs577039731,2
    C--47834213(+) TATAT-/AT/ATATA
    T
    /ATATATAT
    TTTTA
    2 -- us2k1 cds10--------
    rs72630691,2
    C,A--47834232(+) tatatA/TtttaG 1 -- us2k10--------
    rs60126151,2
    C--47834255(+) ggctcA/Gtgcct 1 -- us2k10--------
    rs60126161,2
    C,F,H--47834352(+) ACACTC/TTCACC 1 -- us2k18Minor allele frequency- T:0.40NS EA CSA WA NA 769
    rs2018760121,2
    --47834419(+) AATAA-/TTTTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX27 (47835832 - 47860614 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DDX27: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DDX27
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX27

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with DDX27           About GenesLikeMe

    Genetic Association Database (GAD): DDX27

    Export disorders for DDX27 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX27 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with DDX27)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    9. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55661 HGNC: 15837 AceView: DDX27 Ensembl:ENSG00000124228 euGenes: HUgn55661
    ECgene: DDX27 H-InvDB: DDX27

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX27 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DDX27 gene:
    Search GeneIP for patents involving DDX27

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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