DDX26B Gene
protein-coding GIFtS : 44
GCID: GC0X P134654
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
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Aliasesfor DDX26B gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 26B 1 2 FLJ412151 Protein DDX26B2
Export aliases for DDX26B gene to outside databases Previous GC identifers: GC0XP134380 GC0XP134482 GC0XP124012
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Summariesfor DDX26B gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor DDX26B gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000023.10 NC_018934.1 NT_011786.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the DDX26B gene promoter: HEN1 AREB6 Other transcription factors Search SABiosciences Chromatin IP Primers for DDX26B Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat DDX26B
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: Xq26.3 Ensembl cytogenetic band: Xq26.3 HGNC cytogenetic band: Xq26 DDX26B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome X GeneLoc Exon Structure
GeneLoc location for GC0XP134654: view genomic region
(about GC identifiers )
Start:
134,654,555 bp from pter
End:
134,716,460 bp from pter
Size:
61,906 bases
Orientation:
plus strand
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Proteinsfor DDX26B gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: DX26B_HUMAN, Q5JSJ4 (See
protein sequence )Recommended Name: Protein DDX26B Size : 861 amino acids; 96673 Da
Secondary accessions : Q5CZA2 Q6IPS3 Q6ZTU5 Q6ZWE4Alternative splicing : 2 isoforms : Q5JSJ4-1 Q5JSJ4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for DDX26B: NX_Q5JSJ4 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q5JSJ4 DDX26B Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_872346.3 ENSEMBL proteins: ENSP00000359788 Human Recombinant Protein Products for DDX26B: DDX26B Antibody Products: Assay Products for DDX26B:
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Protein
Domains / Familiesfor DDX26B gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
DDX26B for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q5JSJ4 ProtoNet protein and cluster: Q5JSJ4
UniProtKB/Swiss-Prot: DX26B_HUMAN, Q5JSJ4 Similarity : Contains 1 VWFA domain
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Functionfor DDX26B gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Phenotypes: 2 GenomeRNAi human phenotypes for DDX26B :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26B (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26BOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DDX26B (NM_182540 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DDX26B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DDX26B
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX26B
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Pathways & Interactionsfor DDX26B gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX26B STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)5/7 Interacting proteins for DDX26B (Q5JSJ4 3 ENSP00000359788 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 7 )About this table
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Drugs & Compoundsfor DDX26B gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for DDX26B Search CenterWatch for drugs/clinical trials and news about DDX26B / DX26B
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Transcriptsfor DDX26B gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for DDX26B gene: NM_182540.4 Unigene Cluster for DDX26B:
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B Hs.496829 [show with all ESTs ] Unigene Representative Sequence: BX648113 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000370752 (uc004eyw.4 uc004eyx.4 ) ENST00000481908 ENST00000493637 ENST00000494957 ENST00000481429 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26B (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26BOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: DDX26B (NM_182540 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DDX26B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DDX26B
Additional cDNA sequence: AK096544.1 AK308423.1 AL833319.1 BC140715.1 BX648113.1 CR936620.1
10 DOTS entries : DT.97764531 DT.443474
DT.100782019 DT.100801610 DT.97779661 DT.121303322 DT.97825102 DT.95319507 DT.92419314 DT.100782018 24/90 AceView cDNA sequences (see all 90 ):
CB160378 BQ446698 BM977827 CA412551 AK126202 AW274563 BQ028227 NM_182540 AI420341 AI085076 BX350756 BQ220487 AV727880 AI968298 BF000403 BF446452 CB162968 AI251025 BX497708 AI912053 AA804561 AI200742 AA332956 AK096544 GeneLoc Exon Structure 5/8 Alternative Splicing Database (ASD) splice patterns (SP) for DDX26B (see all 8 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16a · SP1 :     -                         -   -     -   -             -   -   SP2 :                                     -               -   SP3 :                                                     SP4 :                                   -   -                 SP5 :     -       -                                          
ExUns: 16b ^ 17 ^ 18a · 18b · 18c SP1 :           SP2 :           SP3 :           SP4 :           SP5 :          
ECgene alternative splicing isoforms for DDX26B
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Expression for DDX26B gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section DDX26B expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGATGATAGAAbout this image See DDX26B Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for DDX26B SOURCE GeneReport for Unigene cluster: Hs.496829 SABiosciences Custom PCR Arrays for DDX26B
Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for DDX26BBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat DDX26B QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat DDX26B QIAGEN QuantiFast Probe-based Assays in human , mouse , rat DDX26B In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX26B
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Orthologsfor DDX26B gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for DDX26B gene from 6/22 species (see all 22 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
DDX26B1
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
78.7(n) 80.38(a)
 
422239 XM_420227.3 XP_420227.3
lizard (Anolis carolinensis)
Reptilia
--
--
72(a)
1 ↔ 1
GL343761.1(61201-94263)
tropical clawed frog (Xenopus tropicalis)
Amphibia
Str.57282
Transcribed sequence with moderate similarity to protein refNP_036273.1 (H.sapiens) DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26; deleted in cancer 1; RNA helicase HDB/DICE1; DEAD box protein; RNA helicase HDB [Homo sapiens] less
77.72(n)
 
137725081
zebrafish (Danio rerio)
Actinopterygii
ddx26b1
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
65.8(n) 71.87(a)
 
393406 NM_200434.1 NP_956728.1
fruit fly (Drosophila melanogaster)
Insecta
IntS61
Integrator 6
51.32(n) 47.69(a)
 
31496 NM_132025.2 NP_572253.2
worm (Caenorhabditis elegans)
Secernentea
dic-16
--
22(a)
1 → many
IV(8692086-8696443)
ENSEMBL Gene Tree for DDX26B (if available)TreeFam Gene Tree for DDX26B (if available)
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Paralogsfor DDX26B gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for DDX26B gene CT45A4 2 CT45A3 2 CT45A2 2 INTS6 2 CT45A5 2 CT45A1 2 SAGE1 2 CT45A6 2 8 SIMAP similar genes for DDX26B using alignment to 3 protein entries: DX26B_HUMAN (see all proteins ):INTS6 CT45A1 CT45A2 CT45A3 CT45A4 CT45A5 CT45A6 SAGE1
DDX26B for paralogs About GeneDecksing
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Genomic Variantsfor DDX26B gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr X pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for DDX26B (134654555 - 134716460 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for DDX26B 1 CNV : 4174
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing DDX26B
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Disorders
/ Diseasesfor DDX26B gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
DDX26B for disorders About GeneDecksing 4 diseases for DDX26B : About MalaCards non-small cell lung carcinoma lung carcinoma carcinoma schizophrenia Export disorders for DDX26B gene to outside databases
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Publicationsfor DDX26B gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for DDX26B gene, integrated from 9 sources (see all 11 ): (articles sorted by number of sources associating them with DDX26B) Utopia : connect your pdf to the dynamic world of online information
The DNA sequence of the human X chromosome. (PubMed id 15772651) 1 , 2 Ross M.T.... Bentley D.R. (2005) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692) 2 Rigbolt K.T....Blagoev B. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) A human MAP kinase interactome. (PubMed id 20936779) 1 Bandyopadhyay S....Ideker T. (2010) Streamlined analysis schema for high-throughput ident ification of endogenous protein complexes. (PubMed id 20133760) 1 Malovannaya A....Qin J. (2010) Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677) 1 Camargo L.M....Brandon N.J. (2007) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197) 1 Brandenberger R.... Stanton L.W. (2004)
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External Searches for DDX26B gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing DDX26B gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing DDX26B gene
(According to HUGE )
About This Section --
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Specialized Databases showing DDX26B gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for DDX26B Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for DDX26B gene: Search GeneIP for patents involving DDX26B GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor DDX26B gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies Browse OriGene shRNA RFPs OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for DDX26B OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for DDX26B Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits Browse OriGene siRNAs OriGene 3'-UTR Clone for DDX26B OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26B OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for DDX26B Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for DDX26B OriGene Custom Protein Services for DDX26B OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DDX26B QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing DDX26B QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat DDX26B QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat DDX26B QIAGEN QuantiFast Probe-based Assays in human , mouse , rat DDX26B QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat DDX26B
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DDX26B Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX26B
Search ThermoFisher Antibodies for DDX26B
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat DDX26B
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Aliases for DDX26B
Databases for DDX26B
Disorders / Diseases for DDX26B
Domains / Families for DDX26B
Drugs / Compounds for DDX26B
Expression for DDX26B
Function for DDX26B
Genomic Views for DDX26B
Intellectual Property for DDX26B
Orthologs for DDX26B
Paralogs for DDX26B
Pathways / Interactions for DDX26B
Products for DDX26B
Proteins for DDX26B
Publications for DDX26B
Search Box for DDX26B
Summaries for DDX26B
Transcripts for DDX26B
Variants for DDX26B
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