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DDX26B Gene

protein-coding   GIFtS: 48
GCID: GC0XP134654

DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 26B

  Search for DDX26B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 26B1 2
Protein DDX26B2

External Ids:    HGNC: 273341   Entrez Gene: 2035222   Ensembl: ENSG000001653597   UniProtKB: Q5JSJ43   

Export aliases for DDX26B gene to outside databases

Previous GC identifers: GC0XP134380 GC0XP134482 GC0XP124012


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DDX26B Gene:
DDX26B (DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B) is a protein-coding gene. An important paralog of this gene is CT45A4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011786.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DDX26B gene promoter:
         HEN1   AREB6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX26B promoter sequence
   Search Chromatin IP Primers for DDX26B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DDX26B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq26.3   Ensembl cytogenetic band:  Xq26.3   HGNC cytogenetic band: Xq26

DDX26B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX26B gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP134654:  view genomic region     (about GC identifiers)

Start:
134,654,555 bp from pter      End:
134,716,460 bp from pter
Size:
61,906 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DX26B_HUMAN, Q5JSJ4 (See protein sequence)
Recommended Name: Protein DDX26B  
Size: 861 amino acids; 96673 Da
Secondary accessions: Q5CZA2 Q6IPS3 Q6ZTU5 Q6ZWE4
Alternative splicing: 2 isoforms:  Q5JSJ4-1   Q5JSJ4-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DDX26B: NX_Q5JSJ4

Explore proteomics data for DDX26B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys838
  • Modification sites at PhosphoSitePlus

  • See DDX26B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_872346.3  
    ENSEMBL proteins: 
     ENSP00000359788  

    DDX26B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for DDX26B

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DDX: DEAD-boxes

    1 InterPro protein domain:
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry Q5JSJ4

    ProtoNet protein and cluster: Q5JSJ4

    UniProtKB/Swiss-Prot: DX26B_HUMAN, Q5JSJ4
    Similarity: Contains 1 VWFA domain


    Find genes that share domains with DDX26B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         2 GenomeRNAi human phenotypes for DDX26B:
     Increased gamma-H2AX phosphory  Synthetic lethal with imatinib 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DDX26B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DDX26B
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    miRNA
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    Block miRNA regulation of human, mouse, rat DDX26B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate DDX26B (see all 27):
    hsa-miR-3149 hsa-miR-429 hsa-let-7d hsa-let-7c hsa-miR-486-3p hsa-let-7g hsa-miR-124 hsa-miR-2115
    SwitchGear 3'UTR luciferase reporter plasmidDDX26B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DDX26B
    Predesigned siRNA for gene silencing in human, mouse, rat DDX26B

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: DDX26B (NM_182540)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX26B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX26B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX26B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DDX26B
    Interactions:

        Search GeneGlobe Interaction Network for DDX26B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for DDX26B (Q5JSJ43 ENSP000003597884) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    INTS5Q6P9B93, ENSP000003278894I2D: score=1 STRING: ENSP00000327889
    CEP63Q96MT83, ENSP000003365244I2D: score=2 STRING: ENSP00000336524
    INTS1Q8N2013, ENSP000003857224I2D: score=1 STRING: ENSP00000385722
    INTS3Q68E013, ENSP000003186414I2D: score=1 STRING: ENSP00000318641
    INTS6Q9UL033, ENSP000003102604I2D: score=1 STRING: ENSP00000310260
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DDX26B (DX26B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DDX26B gene: 
    NM_182540.4  

    Unigene Cluster for DDX26B:

    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
    Hs.496829  [show with all ESTs]
    Unigene Representative Sequence: BX648113
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370752(uc004eyw.4 uc004eyx.4) ENST00000481908 ENST00000493637
    ENST00000494957 ENST00000481429
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate DDX26B (see all 27):
    hsa-miR-3149 hsa-miR-429 hsa-let-7d hsa-let-7c hsa-miR-486-3p hsa-let-7g hsa-miR-124 hsa-miR-2115
    SwitchGear 3'UTR luciferase reporter plasmidDDX26B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DDX26B
    Predesigned siRNA for gene silencing in human, mouse, rat DDX26B
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    OriGene ORF clones in mouse, rat for DDX26B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DDX26B (NM_182540)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX26B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX26B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for DDX26B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DDX26B
      QuantiTect SYBR Green Assays in human, mouse, rat DDX26B
      QuantiFast Probe-based Assays in human, mouse, rat DDX26B

    Additional mRNA sequence: 

    AK096544.1 AK308423.1 AL833319.1 BC140715.1 BX648113.1 CR936620.1 

    10 DOTS entries:

    DT.97764531  DT.443474  DT.100782019  DT.100801610  DT.97779661  DT.121303322  DT.97825102  DT.95319507 
    DT.92419314  DT.100782018 

    Selected AceView cDNA sequences (see all 90):

    NM_182540 AI968298 CB160378 BM977827 AV727880 AK126202 AI420341 CB162968 
    AI085076 CA412551 BQ220487 BF446452 BQ028227 BF000403 BQ446698 AI251025 
    AW274563 BX350756 AA904585 W69573 AA993435 BI712887 AK123209 AI200742 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DDX26B (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15a · 15b ^ 16a ·
    SP1:              -                                                                       -     -           -     -                                   -     -   
    SP2:                                                                                                              -                                         -   
    SP3:                                                                                                                                                            
    SP4:                                                                                                        -     -                                             
    SP5:              -                 -                                                                                                                           

    ExUns: 16b ^ 17 ^ 18a · 18b · 18c
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for DDX26B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DDX26B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATGATAGA
    DDX26B Expression
    About this image


    DDX26B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Dermis (Integumentary System)    fully expand to see all 2 entries
             Zigzag Dermal Papilla Cells Dermal Papilla
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
    DDX26B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DDX26B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.496829
        Custom PCR Arrays for DDX26B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX26B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DDX26B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx26b1 , 5 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B1, 5 90.4(n)1
    90.36(a)1
      X (30.06 cM)5
    2367901  NM_172779.41  NP_766367.11 
     564548575 
    chicken
    (Gallus gallus)
    Aves DDX26B1 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B 78.53(n)
    80.23(a)
      422239  XM_004940674.1  XP_004940731.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    71(a)
    1 → many
    GL343761.1(61201-94435)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.57282 Transcribed sequence with moderate similarity to protein more 77.72(n)    137725081 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx26b1 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B 65.84(n)
    71.87(a)
      393406  NM_200434.1  NP_956728.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta IntS61 Integrator 6 54.23(n)
    52.73(a)
      31496  NM_001272332.1  NP_001259261.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dic-16
    Protein DIC-1, isoform b
    23(a)
    1 → many
    IV(8692099-8696456) WBGene00000994


    ENSEMBL Gene Tree for DDX26B (if available)
    TreeFam Gene Tree for DDX26B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DDX26B gene
    CT45A42  CT45A32  CT45A22  INTS62  CT45A52  CT45A12  SAGE12  CT45A62  
    8 SIMAP similar genes for DDX26B using alignment to 3 protein entries:     DX26B_HUMAN (see all proteins):
    INTS6    CT45A1    CT45A2    CT45A3    CT45A4    CT45A5
    CT45A6    SAGE1

    Find genes that share paralogs with DDX26B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DDX26B (see all 716)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1815278711,2
    --134610888(+) CTGCCC/TCCAAC 1 -- us2k10--------
    rs1860388991,2
    --134610901(+) TCCTAC/TATTTT 1 -- us2k10--------
    rs1895771051,2
    --134610913(+) TGTACC/TCTAGC 1 -- us2k10--------
    rs1476764411,2
    C--134611304(+) CATAC-/ATAT  
            
    CATAT
    1 -- us2k10--------
    rs575460631,2
    C--134611315(+) ATATA-/TATA  
            
    GAGAG
    1 -- us2k10--------
    rs584588541,2
    C--134611316(+) ATATAT/GAGAGA 1 -- us2k12Minor allele frequency- G:0.33WA CSA 3
    rs134405441,2
    C--134611341(+) gagagA/Tgtgta 1 -- us2k1 trp30--------
    rs1819168221,2
    --134611366(+) AATACC/TTTTTT 1 -- us2k10--------
    rs1854707771,2
    --134611597(+) TGATCC/TACCCA 1 -- us2k10--------
    rs128401691,2
    C--134611603(+) ACCCAA/CCTCGG 1 -- us2k12Minor allele frequency- C:0.00NA 4

    HapMap Linkage Disequilibrium report for DDX26B (134654555 - 134716460 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DDX26B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv522205CNV Gain19592680
    dgv531n21CNV Gain19592680
    esv785CNV CNV17122850
    dgv2477e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DDX26B
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX26B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DDX26B gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with DDX26B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Diagnostic exome sequencing in persons with severe intellectual disability. (PubMed id 23033978)2 de Ligt J.... Vissers L.E. (N. Engl. J. Med. 2012)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (Nat. Methods 2010)
    7. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. (PubMed id 20133760)1 Malovannaya A....Qin J. (Proc. Natl. Acad. Sci. U.S.A. 2010)
    8. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (Mol. Psychiatry 2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 203522 HGNC: 27334 AceView: DDX26B Ensembl:ENSG00000165359 euGenes: HUgn203522
    ECgene: DDX26B H-InvDB: DDX26B

    (According to HUGE)
    About This Section

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DDX26B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for DDX26B gene:
    Search GeneIP for patents involving DDX26B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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