Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX24 Gene

protein-coding   GIFtS: 54
GCID: GC14M094517

DEAD (Asp-Glu-Ala-Asp) box polypeptide 24

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24 )
 Explore 4 diseases affiliated with
DDX24 via our new
 Human Malady Compendium 
Biological research products
for DDX24
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 241 2     S. Cerevisiae CHL1-Like Helicase2
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 241 2     EC 3.6.4.133
DEAD Box Protein 242 3     EC 3.6.18
ATP-Dependent RNA Helicase DDX242     

External Ids:    HGNC: 132661   Entrez Gene: 570622   Ensembl: ENSG000000897377   OMIM: 6061815   UniProtKB: Q9GZR73   

Export aliases for DDX24 gene to outside databases

Previous GC identifers: GC14M092024 GC14M088333 GC14M092507 GC14M093587 GC14M074697


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX24:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular
growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known
human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: DDX24_HUMAN, Q9GZR7
Function: ATP-dependent RNA helicase (Potential)

Gene Wiki entry for DDX24


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX24 gene promoter:
         HOXA9B   HOXA9   STAT1   CUTL1   Tal-1beta   LCR-F1   E47   c-Rel   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDDX24 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32   Ensembl cytogenetic band:  14q32.12   HGNC cytogenetic band: 14q32

DDX24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX24 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M094517:  view genomic region     (about GC identifiers)

Start:
94,517,266 bp from pter      End:
94,547,591 bp from pter
Size:
30,326 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DDX24_HUMAN, Q9GZR7 (See protein sequence)
Recommended Name: ATP-dependent RNA helicase DDX24  
Size: 859 amino acids; 96332 Da

Explore the universe of human proteins at neXtProt for DDX24: NX_Q9GZR7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9GZR7

  • 4/13 DME Specific Peptides for DDX24 (Q9GZR7) (see all 13)
     TPTRELA  TRELAVQ  LVFANSI  VATPGRL 

    DDX24 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065147.1  
    ENSEMBL proteins: 
     ENSP00000328690   ENSP00000440623   ENSP00000452145  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: DDX24
    OriGene Custom Protein Services for DDX24 
    GenScript Custom Purified and Recombinant Proteins Services for DDX24
    Novus Biologicals DDX24 Proteins
    Novus Biologicals DDX24 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX24

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--


    DDX24 for ontologies           About GeneDecksing



    DDX24 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DDX24 
    GenScript Custom Superior Antibodies Services for DDX24
    Novus Biologicals DDX24 Antibodies
    Search for Antibodies for DDX24 at Abcam  
    Uscn Antibodies for DDX24
    Search ThermoFisher Antibodies for DDX24

    Assay Products for DDX24: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DDX24
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DDX24


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DDX24 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q9GZR7

    ProtoNet protein and cluster: Q9GZR7

    1 Blocks protein family: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX24_HUMAN, Q9GZR7
    Similarity: Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DDX24_HUMAN, Q9GZR7
    Function: ATP-dependent RNA helicase (Potential)
    Catalytic activity: ATP + H(2)O = ADP + phosphate

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: DDX24
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX24
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX24:
    hsa-miR-550b hsa-miR-3919 hsa-miR-3925-5p
    SwitchGear 3'UTR luciferase reporter plasmidDDX24 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX24 (see all 7)
    OriGene shRNA RFP: DDX24
    OriGene siRNA: DDX24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX24

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DDX24

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: DDX24 (NM_020414)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX24 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DDX24
    Search LifeMap BioReagents cell lines for DDX24

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX24

    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0003724RNA helicase activity NAS10936056
    GO:0004004ATP-dependent RNA helicase activity NAS--
    GO:0005524ATP binding IEA--


    DDX24 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for DDX24:
     Decreased TP53 protein express  Nuclear 60S biogenesis defects 

    Animal Models:
         1 MGI phenotypic allele for Ddx24 (no phenotypes)

    DDX24 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX24

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/145 Interacting proteins for DDX24 (Q9GZR72, 3 ENSP000003286904) via UniProtKB, MINT, STRING, and/or I2D (see all 145)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IDO1P149022, 3, ENSP000002535134MINT-65410 I2D: score=5 STRING: ENSP00000253513
    MRPL4Q9BYD32, 3, ENSP000002530994MINT-65430 I2D: score=4 STRING: ENSP00000253099
    RAE1P784062, 3, ENSP000003602864MINT-65413 I2D: score=4 STRING: ENSP00000360286
    BCS1LQ9Y2762, 3MINT-65427 I2D: score=5 
    EIF3EP602282, 3MINT-65412 I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016070RNA metabolic process NAS10936056


    DDX24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX24
    Search CenterWatch for drugs/clinical trials and news about DDX24 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX24 gene: 
    NM_020414.3  

    Unigene Cluster for DDX24:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
    Hs.510328  [show with all ESTs]
    Unigene Representative Sequence: BX537533
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555762 ENST00000553400 ENST00000553451 ENST00000330836(uc001ycj.3 uc010twq.2 uc010twr.2)
    ENST00000544005 ENST00000555054 ENST00000556635 ENST00000555324

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: DDX24
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX24
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX24:
    hsa-miR-550b hsa-miR-3919 hsa-miR-3925-5p
    SwitchGear 3'UTR luciferase reporter plasmidDDX24 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX24 (see all 7)
    OriGene shRNA RFP: DDX24
    OriGene siRNA: DDX24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX24
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: DDX24 (NM_020414)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DDX24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX24 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX24
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDX24
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX24
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX24

    Additional cDNA sequence: 

    AB209382.1 AF134475.1 AF145022.1 AF161446.1 AF214731.1 AK025162.1 AK294613.1 AK296726.1 
    AK297232.1 AK304504.1 AL136886.1 BC000778.2 BC008847.2 BC009406.2 BC096826.1 BX537533.1 

    24/37 DOTS entries (see all 37):

    DT.100045283  DT.40194546  DT.100805292  DT.95158971  DT.100881341  DT.100881334  DT.120774513  DT.87010521 
    DT.120774532  DT.120774567  DT.95278831  DT.95278807  DT.100881333  DT.120774578  DT.100045281  DT.120774500 
    DT.120774541  DT.120774558  DT.75148906  DT.87079269  DT.95278842  DT.100638833  DT.100881342  DT.120774488 

    24/1050 AceView cDNA sequences (see all 1050):

    BU854828 AI277700 AW955238 BQ056891 CD369822 BQ919221 AW630221 BQ928935 
    BQ671372 BM983553 BQ645946 BU174036 BQ065898 CR596324 BU157046 BU858210 
    BM128332 T30931 BF340241 BQ061971 AI362268 BQ878442 BP344528 BQ642580 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for DDX24 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c
    SP1:                                                                                                              -           -                     
    SP2:                                                                                                              -           -                     
    SP3:                                                                                                                                                
    SP4:                                      -     -                                                                                                   
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for DDX24

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGATTTGCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DDX24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX24

    SOURCE GeneReport for Unigene cluster: Hs.510328

    UniProtKB/Swiss-Prot: DDX24_HUMAN, Q9GZR7
    Tissue specificity: Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine

        SABiosciences Custom PCR Arrays for DDX24
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX24
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDX24
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX24
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX24
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX24 gene from 10/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ddx241 , 5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 241, 5 82.24(n)1
    80.28(a)1
      12 (52.92 cM)5
    272251  NM_001159502.11  NP_001152974.11 
     1034079765 
    chicken
    (Gallus gallus)
    Aves DDX241 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 63.41(n)
    62.47(a)
      423429  XM_421338.3  XP_421338.3 
    lizard
    (Anolis carolinensis)
    Reptilia DDX246
    --
    57(a)
    1 ↔ 1
    1(10300209-10313224)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984462 similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide more 73.88(n)    BC043900.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5534621 uncharacterized LOC553462 58.23(n)
    54.22(a)
      553462  XM_003200406.1  XP_003200454.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG91431 , 3 ATP dependent RNA helicase3
    CG91431
    48(a)3
    50.94(n)1
    40.53(a)1
      372961  NM_137623.21  NP_611467.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F55F8.21 Protein F55F8.2 47.93(n)
    39.01(a)
      172223  NM_059251.2  NP_491652.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MAK5(YBR142W)4
    MAK51
    Essential nucleolar protein, putative DEAD-box RNA more4
    Mak5p1
    45.42(n)1
    35.58(a)1
      2(528317-530638)4
    8524391, 4  NP_009700.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G168401 DEAD-box ATP-dependent RNA helicase 13 47.83(n)
    37.06(a)
      820937  NM_112558.5  NP_188307.3 
    rice
    (Oryza sativa)
    Liliopsida Os04g05104001 hypothetical protein 48.88(n)
    38.46(a)
      4336370  NM_001059821.1  NP_001053286.1 


    ENSEMBL Gene Tree for DDX24 (if available)
    TreeFam Gene Tree for DDX24 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX24 gene
    6 SIMAP similar genes for DDX24 using alignment to 4 protein entries:     DDX24_HUMAN (see all proteins):
    DDX56    DDX39B    MST162    DDX47    E4-DBP    DDX18

    DDX24 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for DDX24
    PGOHUM00000263156


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/665 NCBI SNPs in DDX24 are shown (see all 665    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118491011,2
    C,F,H,--94517242(+) AAAAAA/GAAAAA 1 -- ds50011Minor allele frequency- G:0.19WA 118
    rs49051501,2
    C--94517258(+) GGATGA/CCACAA 1 -- ds50012Minor allele frequency- C:0.00NA 4
    rs1468795731,2
    --94517305(+) TTTAAC/TACACA 1 -- ut310--------
    rs1907270671,2
    --94517314(+) CAAGAA/GGCCTA 1 -- ut310--------
    rs802715961,2
    C,F,--94517348(+) TAAGCT/CGCTGC 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs1817276971,2
    C,--94517514(+) ATGTGC/TAGTCA 1 -- ut310--------
    rs1995991131,2
    C--94517538(-) AAATTA/CACTGG 2 * S --0--------
    rs617442651,2
    F--94517543(+) TAATTT/CGCACT 2 /A syn11Minor allele frequency- C:0.04NS 66
    rs1118125161,2
    C,F,--94517561(+) GGCTGT/CGGCTG 2 /P syn12Minor allele frequency- C:0.00CSA NA 4519
    rs2021935261,2
    --94517593(+) CTTCTA/TTGTCT 2 K * stg10--------

    HapMap Linkage Disequilibrium report for DDX24 (94517266 - 94547591 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for DDX24
         1 CNV: 47863

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX24
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DDX24 for disorders           About GeneDecksing

    OMIM gene information: 606181    OMIM disorders: --

    4 diseases for DDX24:    About MalaCards
    hepatitis b    hepatitis    immunodeficiency    malaria

    Human Genome Epidemiology (HuGE) Navigator: DDX24 (1 document)

    Export disorders for DDX24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX24 gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with DDX24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of human DDX24 and mouse Ddx24, two novel putative DEAD-box proteins, and mapping DDX24 to human chromosome 14q32. (PubMed id 10936056)1, 2, 3 Zhao Y.... Zhao S. (2000)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57062 HGNC: 13266 AceView: DDX24 Ensembl:ENSG00000089737 euGenes: HUgn57062
    ECgene: DDX24 H-InvDB: DDX24

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX24 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX24 gene:
    Search GeneIP for patents involving DDX24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for DDX24  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX24   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDX24  
     OriGene Protein Over-expression Lysate for DDX24   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for DDX24   OriGene 3'-UTR Clone for DDX24  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDX24  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DDX24   OriGene Custom Protein Services for DDX24  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DDX24
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX24
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX24
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX24
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX24
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX24
     GenScript Custom Purified and Recombinant Proteins Services for DDX24 GenScript cDNA clones with any tag delivered in your preferred vector for DDX24
     GenScript Custom Assay Services for DDX24 GenScript Custom Superior Antibodies Services for DDX24
     GenScript Custom overexpressing Cell Line Services for DDX24 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DDX24 promoter
     Search Chromatin IP Primers for DDX24
     RT2 qPCR Primer Assay in human, mouse, rat DDX24
     Search GNC Networks for DDX24
     SABiosciences Custom PCR Arrays for DDX24
     Search Tocris compounds for DDX24
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     DDX24 antibodies
     DDX24 proteins
     DDX24 lysates
     Search for Antibodies for DDX24 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for DDX24
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     DDX24 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for DDX24
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX24
     SwitchGear 3'UTR luciferase reporter plasmids for DDX24
     SwitchGear Promoter luciferase reporter plasmids for DDX24
     Search ThermoFisher Antibodies for DDX24
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX24
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DDX24 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4