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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX19B Gene

protein-coding   GIFtS: 51
GCID: GC16P070328

DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B

(Previous names: DEAD (Asp-Glu-Ala-As) box polypeptide 19, DEAD/H (Asp-Glu-Ala-Asp/His)...)
(Previous symbol: DDX19)
 Explore 5 diseases affiliated with
DDX19B via our new
 Human Malady Compendium 
Biological research products
for DDX19B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 19B1 2     ATP-Dependent RNA Helicase DDX19B2
DBP51 2 3 5     DEAD (Asp-Glu-Ala-As) Box Polypeptide 19B2
DDX191 2 3 5     DEAD-Box Protein 52
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 19 (Dbp5, Yeast, Homolog)1 2     DEAD-Box RNA Helicase DEAD52
DEAD Box Protein 19B2 3     Yeast Dbp5 Homolog2
DEAD Box RNA Helicase DEAD52 3     EC 3.6.4.133
DEAD (Asp-Glu-Ala-As) Box Polypeptide 191     TDBP3
RNAh2     EC 3.6.18
ATP-Dependent RNA Helicase DDX192     

External Ids:    HGNC: 27421   Entrez Gene: 112692   Ensembl: ENSG000001573497   OMIM: 6058125   UniProtKB: Q9UMR23   

Export aliases for DDX19B gene to outside databases

Previous GC identifers: GC16P068891 GC16P056165


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX19B:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular
growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent
RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it
participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DD19B_HUMAN, Q9UMR2
Function: ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes,
DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated
and replaced by cytoplasmic mRNA binding proteins

Gene Wiki entry for DDX19B


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX19B gene promoter:
         Elk-1   C/EBPbeta   Pbx1a   ATF-2   GATA-2   MZF-1   CRE-BP1   E2F   E2F-1   NF-Y   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for DDX19B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX19B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.3

DDX19B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX19B gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P070328:  view genomic region     (about GC identifiers)

Start:
70,323,566 bp from pter      End:
70,369,186 bp from pter
Size:
45,621 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DD19B_HUMAN, Q9UMR2 (See protein sequence)
Recommended Name: ATP-dependent RNA helicase DDX19B  
Size: 479 amino acids; 53927 Da
Subunit: Interacts with NUP214 or RNA in a mutually exclusive manner
Subcellular location: Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein;
Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils
6 PDB 3D structures from and Proteopedia for DDX19B:
3EWS (3D)        3FHC (3D)        3FHT (3D)        3FMO (3D)        3FMP (3D)        3G0H (3D)    
Secondary accessions: B3KNE9 B4DXS6 E7EMK4 Q6FIB7 Q6IAE0 Q96KE7 Q9H0U0
Alternative splicing: 4 isoforms:  Q9UMR2-1   Q9UMR2-2   Q9UMR2-3   Q9UMR2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DDX19B: NX_Q9UMR2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UMR2

  • 4/15 DME Specific Peptides for DDX19B (Q9UMR2) (see all 15)
     FVLDEAD  ALCNLYG  VINFDLP  SPLYSVK 

    DDX19B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (7 alternative transcripts): 
    NP_001014449.1  NP_001014451.1  NP_001244101.1  NP_001244102.1  NP_001244103.1  NP_001244104.1  NP_009173.1  

    ENSEMBL proteins: 
     ENSP00000454495   ENSP00000456574   ENSP00000455813   ENSP00000392639   ENSP00000456757  
     ENSP00000288071   ENSP00000455193   ENSP00000377267   ENSP00000454571   ENSP00000459407  
     ENSP00000457633   ENSP00000348271   ENSP00000457366  

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    Novus Biologicals DDX19B Proteins
    Novus Biologicals DDX19B Lysates
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    Uscn Proteins for DDX19B

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IDA--
    GO:0005643nuclear pore IEA--
    GO:0005737cytoplasm IEA--
    GO:0031965nuclear membrane IEA--


    DDX19B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DDX19B for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q9UMR2

    ProtoNet protein and cluster: Q9UMR2

    UniProtKB/Swiss-Prot: DD19B_HUMAN, Q9UMR2
    Domain: The N-terminal extension helix acts as an autoinhibitory domain, preventing ATP hydrolysis, unless the
    N-terminus of the protein is displaced by RNA binding, allowing cleft closure to bring key side chains into position
    for catalysis
    Similarity: Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DD19B_HUMAN, Q9UMR2
    Function: ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes,
    DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated
    and replaced by cytoplasmic mRNA binding proteins
    Catalytic activity: ATP + H(2)O = ADP + phosphate

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

    miRNA
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    hsa-miR-579 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-miR-548m hsa-let-7g hsa-let-7a hsa-miR-630
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0004386helicase activity TAS10428971
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--


    DDX19B for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for DDX19B:
     Decreased TP53 protein express  Decreased viability of wild-ty  Increased cell number in G1, a  Increased gamma-H2AX phosphory 
     Wnt reporter downregulated 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX19B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/766 Interacting proteins for DDX19B (Q9UMR22, 3 ENSP000002880714) via UniProtKB, MINT, STRING, and/or I2D (see all 766)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBA5Q9GZZ92, 3MINT-7945693 MINT-7947479 I2D: score=1 
    PRKAG1P546192, 3MINT-7945693 I2D: score=1 
    RAE1P784062, 3, ENSP000003602864MINT-7945693 I2D: score=1 STRING: ENSP00000360286
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    SNW1Q135732, ENSP000002615314MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006406mRNA export from nucleus TAS10428971
    GO:0015031protein transport IEA--


    DDX19B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX19B
    Search CenterWatch for drugs/clinical trials and news about DDX19B / DD19B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX19B gene (7 alternative transcripts): 
    NM_001014449.2  NM_001014451.2  NM_001257172.1  NM_001257173.1  NM_001257174.1  NM_001257175.1  NM_007242.5  

    Unigene Cluster for DDX19B:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
    Hs.221761  [show with all ESTs]
    Unigene Representative Sequence: NM_007242
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000566216 ENST00000563392 ENST00000570055 ENST00000563206(uc010vlv.2)
    ENST00000451014 ENST00000569099 ENST00000568625(uc010vlw.2) ENST00000288071(uc002eyo.3 uc002eyp.3 uc002eyq.3)
    ENST00000562519(uc010vlx.2) ENST00000393657 ENST00000568008 ENST00000562912
    ENST00000568460 ENST00000355992 ENST00000568408 ENST00000569224

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    hsa-miR-579 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-miR-548m hsa-let-7g hsa-let-7a hsa-miR-630
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    Additional cDNA sequence: 

    AF353720.1 AJ237946.1 AK027378.1 AK223115.1 AK296868.1 AK301938.1 AK302107.1 AK316346.1 
    AL136639.1 BC003626.2 BC010008.2 BC110805.1 CR457215.1 CR533509.1 

    19 DOTS entries:

    DT.92466978  DT.409196  DT.95240705  DT.100795831  DT.95266037  DT.92467020  DT.95266038  DT.453128 
    DT.92466985  DT.95266032  DT.100795842  DT.120659649  DT.120659666  DT.99967772  DT.97860045  DT.100795830 
    DT.100795833  DT.101959511  DT.120659573 

    24/474 AceView cDNA sequences (see all 474):

    BG769156 AK027378 BU557013 BM988409 CR593012 CD367602 BC025771 BE019902 
    BE250004 BQ939975 BC005162 BU552534 BQ014410 BP357159 BQ940784 AL138068 
    BM683133 BC010008 BQ648878 BE297181 BQ427656 NM_007242 BU171888 CA307640 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for DDX19B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
    SP1:                                      -     -               
    SP2:              -                       -                     
    SP3:                                                            


    ECgene alternative splicing isoforms for DDX19B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX19B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATACACAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DDX19B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX19B

    SOURCE GeneReport for Unigene cluster: Hs.221761
        SABiosciences Custom PCR Arrays for DDX19B
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX19B gene from 7/27 species (see all 27)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DDX19B1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 82.88(n)
    93.95(a)
      426504  NM_001006568.1  NP_001006568.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia ddx19-prov2 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 more 80.07(n)    BC046696.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ddx192 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 more 77.62(n)   192339  BC044541.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dbp806
    Gem36
    Gemin3
    52(a)
    12(a)
    1 ↔ many
    possible ortholog
    3LHet(2409852-2545146)
    3L(10452181-10456201)
    worm
    (Caenorhabditis elegans)
    Secernentea ddx-196
    DEAD boX helicase homolog family member (ddx-19)
    23(a)
    1 → many
    II(8884839-8889623)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons LOS46
    DEAD-box ATP-dependent RNA helicase 38
    32(a)
    1 → many
    3(19687740-19690661)
    rice
    (Oryza sativa)
    Liliopsida --
    DEAD-box ATP-dependent RNA helicase, putative, exp...
    31(a)
    1 → many
    3(3114962-3119763)


    ENSEMBL Gene Tree for DDX19B (if available)
    TreeFam Gene Tree for DDX19B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX19B gene
    DDX252  DDX19A2  ENSG000002605372  
    18/19 SIMAP similar genes for DDX19B using alignment to 8 protein entries:     DD19B_HUMAN (see all proteins) (see all similar genes):
    DDX19L    DKFZp686C21137    DKFZp762C1313    DDX19A    DDX25    DDX56
    EIF4A2    DKFZp547B159    EIF4A3    MST162    BAT1    EIF4A1
    DDX39B    DDX6    DDX39A    DDX47    E4-DBP    DDX20

    DDX19B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/647 NCBI SNPs in DDX19B are shown (see all 647    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2020074841,2
    --70325661(+) TGAGC-/CGAG  
            
    CGAGA
    1 -- int10--------
    rs1870883111,2
    --70325761(+) TAAGAC/GAGATT 1 -- int10--------
    rs598498981,2
    C,--70325940(+) TCCCAG/TCTGCT 1 -- int12Minor allele frequency- T:0.31WA 120
    rs1173049071,2
    F,--70326011(+) GATCTC/TGCGAC 1 -- int11Minor allele frequency- T:0.03EA 120
    rs1480557721,2
    C,--70326188(+) AGGCG-/CCCACC 1 -- int10--------
    rs1900466771,2
    --70326189(+) CAGGCA/GCCACC 1 -- int10--------
    rs1159697861,2
    F,--70326345(+) GCGTCC/TGGCCC 1 -- int11Minor allele frequency- T:0.03WA 118
    rs614663211,2
    C,--70326346(+) CGTCCG/AGCCCC 1 -- int12Minor allele frequency- A:0.15WA 120
    rs1409156941,2
    --70326434(+) ATATTC/TTTCTG 1 -- int10--------
    rs118663781,2
    C,F,H,--70326467(+) TCAACT/AACATG 1 -- int19Minor allele frequency- A:0.12NS EA NA WA 720

    HapMap Linkage Disequilibrium report for DDX19B (70323566 - 70369186 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for DDX19B
         2 CNVs: 4964 67025

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX19B
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DDX19B for disorders           About GeneDecksing

    OMIM gene information: 605812    OMIM disorders: --

    5 diseases for DDX19B:    About MalaCards
    locked-in syndrome    werner syndrome    apraxia    pneumonia
    malaria


    Export disorders for DDX19B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX19B gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with DDX19B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p. (PubMed id 10428971)1, 2, 3 Schmitt C....Izaurralde E. (1999)
    2. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. (PubMed id 19219046)1, 2, 9 von Moeller H....Conti E. (2009)
    3. The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch. (PubMed id 19244245)1, 2 Collins R....SchA1ler H. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Identification and characterization of a gene coding a novel isoform of DEAD-box protein. (PubMed id 12219940)1, 2 Yin L.... Sha J. (2002)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. Dbp5, Gle1-IP6 and Nup159: a working model for mRNP ex port. (PubMed id 22064466)1 Folkmann A.W....Wente S.R. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11269 HGNC: 2742 AceView: DDX19andFLJ11126 Ensembl:ENSG00000157349 euGenes: HUgn11269
    ECgene: DDX19B H-InvDB: DDX19B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX19B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX19B gene:
    Search GeneIP for patents involving DDX19B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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