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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX18 Gene

protein-coding   GIFtS: 57
GCID: GC02P118572

DEAD (Asp-Glu-Ala-Asp) box polypeptide 18

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)...)
 Explore 5 diseases affiliated with
DDX18 via our new
 Human Malady Compendium 
Biological research products
for DDX18
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 181 2     Myc-Regulated DEAD Box Protein2 3
MrDb1 2 3     ATP-Dependent RNA Helicase DDX182
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 18 (Myc-Regulated)1 2     EC 3.6.4.133
DEAD Box Protein 182 3     EC 3.6.18

External Ids:    HGNC: 27411   Entrez Gene: 88862   Ensembl: ENSG000000882057   OMIM: 6063555   UniProtKB: Q9NVP13   

Export aliases for DDX18 gene to outside databases

Previous GC identifers: GC02P115777 GC02P116493 GC02P118479 GC02P118667 GC02P118288 GC02P110899


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DDX18:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular
growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. (provided by RefSeq,
Jul 2008)

UniProtKB/Swiss-Prot: DDX18_HUMAN, Q9NVP1
Function: Probable RNA-dependent helicase




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022135.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX18 gene promoter:
         c-Fos   Egr-1   Pax-2   Pax-2a   AREB6   PPAR-gamma1   Pax-2b   COMP1   Chx10   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DDX18 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.1   Ensembl cytogenetic band:  2q14.1   HGNC cytogenetic band: 2q21.2

DDX18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX18 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P118572:  view genomic region     (about GC identifiers)

Start:
118,572,226 bp from pter      End:
118,589,955 bp from pter
Size:
17,730 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DDX18_HUMAN, Q9NVP1 (See protein sequence)
Recommended Name: ATP-dependent RNA helicase DDX18  
Size: 670 amino acids; 75407 Da
Subunit: Interacts with NOL8; the interaction is RNA-dependent
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=CAA67295.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for DDX18:
3LY5 (3D)    
Secondary accessions: Q6GTZ9 Q6IAU4 Q92732 Q9BQB7

Explore the universe of human proteins at neXtProt for DDX18: NX_Q9NVP1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NVP1

  • 4/24 DME Specific Peptides for DDX18 (Q9NVP1) (see all 24)
     RVGRTAR  FLIPAVE  KRTTTFF  PRNGTGV 

    DDX18 Protein expression data from MOPED and PaxDb:    About this image 
    DDX18 Protein Expression
    REFSEQ proteins: NP_006764.3  
    ENSEMBL proteins: 
     ENSP00000263239   ENSP00000415604  

    Human Recombinant Protein Products for DDX18: 
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    Novus Biologicals DDX18 Protein
    Novus Biologicals DDX18 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX18

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA16963496

    DDX18 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DDX18 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR025313 DUF4217
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q9NVP1

    ProtoNet protein and cluster: Q9NVP1

    1 Blocks protein family: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX18_HUMAN, Q9NVP1
    Similarity: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DDX18_HUMAN, Q9NVP1
    Function: Probable RNA-dependent helicase
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0004004ATP-dependent RNA helicase activity TAS8861962
    GO:0005515protein binding IPI16963496
    GO:0005524ATP binding IEA--
         
    DDX18 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for DDX18:
     Decreased viability of wild-ty  Increased S DNA content  Increased gamma-H2AX phosphory  Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DDX18 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX18
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX18 (see all 13):
    hsa-miR-3673 hsa-miR-18a hsa-miR-425 hsa-miR-551b* hsa-miR-211 hsa-miR-103a hsa-miR-409-5p hsa-miR-144
    SwitchGear 3'UTR luciferase reporter plasmidDDX18 3' UTR sequence
    Inhib. RNA
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    OriGene siRNA: DDX18
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX18


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Validated targets of C-MYC transcriptional activation
    Validated targets of C-MYC transcriptional activation1.00


    1 BioSystems Pathway for DDX18 
        Validated targets of C-MYC transcriptional activation


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/306 Interacting proteins for DDX18 (Q9NVP12, 3 ENSP000002632394) via UniProtKB, MINT, STRING, and/or I2D (see all 306)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    DDX18 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX18
    1 Novoseek chemical compound relationship for DDX18 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oligonucleotide 26.1 1 10704843 (1)

    Search CenterWatch for drugs/clinical trials and news about DDX18 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DDX18 gene: 
    NM_006773.3  

    Unigene Cluster for DDX18:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
    Hs.363492  [show with all ESTs]
    Unigene Representative Sequence: AB209392
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263239(uc002tlh.1) ENST00000474694 ENST00000489933 ENST00000415038
    ENST00000476149 ENST00000461443

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX18
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate DDX18 (see all 13):
    hsa-miR-3673 hsa-miR-18a hsa-miR-425 hsa-miR-551b* hsa-miR-211 hsa-miR-103a hsa-miR-409-5p hsa-miR-144
    SwitchGear 3'UTR luciferase reporter plasmidDDX18 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX18 (see all 7)
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    Sirion Biotech Custom design and validation of potent shRNA sequences against DDX18 
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDX18 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDX18
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    Additional cDNA sequence: 

    AB209392.1 AK001467.1 AK091227.1 BC001238.1 BC003360.1 BC024739.1 CR457060.1 DQ655975.2 
    DQ655976.2 X98743.1 

    19 DOTS entries:

    DT.91757778  DT.99941940  DT.100885389  DT.100885395  DT.100885397  DT.100885396  DT.120994004  DT.91697485 
    DT.92018606  DT.98131941  DT.98131947  DT.100042167  DT.100807493  DT.120837138  DT.120993959  DT.120994003 
    DT.95213849  DT.98131944  DT.120747786 

    24/427 AceView cDNA sequences (see all 427):

    AA829127 BM451096 BG031303 BX446830 CD514318 AI472521 BX504268 BX332834 
    CB117405 BI094337 CA424699 AI380335 CB134802 AU138185 BM697929 BQ424822 
    AL120880 BQ226079 AW183624 BU674531 BM746638 CB130687 CA429507 BX952229 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for DDX18    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                                                                                                            
    SP2:                                      -                                                                     
    SP3:                                                                    -                                       
    SP4:                                                                                                            


    ECgene alternative splicing isoforms for DDX18

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTATTTTCCT
    DDX18 Expression
    About this image
    See DDX18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX18

    SOURCE GeneReport for Unigene cluster: Hs.363492
        SABiosciences Custom PCR Arrays for DDX18

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDX18

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX18 gene from 9/39 species (see all 39)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DDX181 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 75.21(n)
    82.21(a)
      424278  XM_422125.3  XP_422125.2 
    lizard
    (Anolis carolinensis)
    Reptilia DDX186
    --
    77(a)
    1 ↔ 1
    1(82159805-82177456)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.238012 Xenopus laevis transcribed sequence with moderate similarity more 78.59(n)    BQ725520.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb1552 sbcb155 76.57(n)   321127  CD758434.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta pit1 , 3 ATP dependent RNA helicase3
    pitchoune1
    72(a)
    (best of 2)3
    60.39(n)1
    62.96(a)1
      93F143
    425951  NM_169991.21  NP_732694.21 
    worm
    (Caenorhabditis elegans)
    Secernentea B0511.61 , 3 helicase3
    Protein B0511.61
    67(a)
    (best of 2)3
    61.01(n)1
    63.74(a)1
      I(10633448-10636276)3
    1729541  NM_060378.31  NP_492779.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HAS1(YMR290C)4
    HAS11
    ATP-dependent RNA helicase; localizes to both the nuclear more4
    Has1p1
    61.63(n)1
    61.22(a)1
      13(851591-850074)4
    8553351, 4  NP_014017.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G186001 DEAD-box ATP-dependent RNA helicase 51 59.31(n)
    56.07(a)
      821391  NM_112746.5  NP_188490.1 
    rice
    (Oryza sativa)
    Liliopsida Os.57992 Transcribed sequence with weak similarity to protein more 70.23(n)    AU225557.1 


    ENSEMBL Gene Tree for DDX18 (if available)
    TreeFam Gene Tree for DDX18 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX18 gene
    18 SIMAP similar genes for DDX18 using alignment to 4 protein entries:     DDX18_HUMAN (see all proteins):
    DDX10    DDX54    EIF4A3    EIF4A2    DDX39B    DDX41
    E4-DBP    MST162    DDX55    DDX4    DDX47    EIF4A1
    DDX49    DKFZp564G1016    DDX5    DDX31    mcdrh    DDX24

    DDX18 for paralogs           About GeneDecksing


    5/7 Pseudogenes.org Pseudogenes for DDX18 (see all 7)
    PGOHUM00000238886 PGOHUM00000242932 PGOHUM00000248216 PGOHUM00000246808 PGOHUM00000240407


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/382 NCBI SNPs in DDX18 are shown (see all 382    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs175671441,2
    C,F,H--118570273(+) TTTGAG/ATAGCT 1 -- us2k19Minor allele frequency- A:0.04NA NS EA 670
    rs1470002081,2
    --118570723(+) GTTGTA/GTCTAT 1 -- us2k10--------
    rs1390556471,2
    --118570767(+) ATCAGA/GTAAAT 1 -- us2k10--------
    rs1852634531,2
    --118570824(+) ATGCAC/TATATA 1 -- us2k10--------
    rs1885518321,2
    --118570888(+) GTTTGC/TGTGTG 1 -- us2k10--------
    rs1415162781,2
    --118570901(+) TGTGCA/GCTCTT 1 -- us2k10--------
    rs1118813961,2
    C--118570914(+) ATTTCT/CGAATC 1 -- us2k12Minor allele frequency- C:0.04CSA WA 120
    rs1138807731,2
    --118570936(+) TGCCTG/TATCAT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1382379411,2
    --118571009(+) GATTTC/TGAAGT 1 -- us2k10--------
    rs1495865181,2
    --118571096(+) TCCAGA/GGTCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DDX18 (118572226 - 118589955 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DDX18: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DDX18 for disorders           About GeneDecksing

    OMIM gene information: 606355    OMIM disorders: --

    5 diseases for DDX18:    About MalaCards
    rheumatoid arthritis    arthritis    lung cancer    neuroblastoma
    malaria

    1 Novoseek disease relationship for DDX18 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 5 18351129 (4)

    Human Genome Epidemiology (HuGE) Navigator: DDX18 (3 documents)

    Export disorders for DDX18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX18 gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with DDX18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo. (PubMed id 8861962)1, 2, 3 Grandori C.... Eisenman R.E. (1996)
    2. NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47. (PubMed id 16963496)1, 2 Sekiguchi T....Nishimoto T. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    6. Cellular studies of MrDb (DDX18). (PubMed id 18351129)1, 9 Dubaele S. and Chene P. (2007)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8886 HGNC: 2741 AceView: DDX18 Ensembl:ENSG00000088205 euGenes: HUgn8886
    ECgene: DDX18 H-InvDB: DDX18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX18 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DDX18 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DDX18 gene:
    Search GeneIP for patents involving DDX18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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