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Aliases for DDX12P Gene

Aliases for DDX12P Gene

  • DEAD/H-Box Helicase 12, Pseudogene 2 3 5
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 12, Pseudogene 2 3
  • CHL1-Related Protein 2 3 4
  • DEAD/H Box Protein 12 3 4
  • HCHLR2 3 4
  • DDX12 3 4
  • CHLR2 3 4
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 12 (CHL1-Like Helicase Homolog, S. Cerevisiae) 3
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 12 (S.Cerevisiae CHL1-Like Helicase) 2
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 12 2
  • CHL1-Like Helicase Homolog 2 (S. Cerevisiae) 2
  • Probable ATP-Dependent RNA Helicase DDX12 3
  • CHL1-Like Helicase Homolog 2 3
  • DEAD/H Box-12 3
  • EC 3.6.1.23 58
  • EC 3.6.4.13 4
  • EC 3.6.1.7 58
  • EC 3.6.1 58

External Ids for DDX12P Gene

Previous HGNC Symbols for DDX12P Gene

  • DDX12

Previous GeneCards Identifiers for DDX12P Gene

  • GC12M009571
  • GC12M009572
  • GC12M009720
  • GC12M010042
  • GC12M010237
  • GC12M010476

Summaries for DDX12P Gene

GeneCards Summary for DDX12P Gene

DDX12P (DEAD/H-Box Helicase 12, Pseudogene) is a Pseudogene. GO annotations related to this gene include RNA binding and ATP-dependent DNA helicase activity.

UniProtKB/Swiss-Prot for DDX12P Gene

  • DNA helicase involved in cellular proliferation. Probably required for maintaining the chromosome segregation (By similarity).

Additional gene information for DDX12P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DDX12P Gene

Genomics for DDX12P Gene

Regulatory Elements for DDX12P Gene

Enhancers for DDX12P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H009283 1.2 Ensembl ENCODE 26.2 +163.5 163507 3 HDGF PKNOX1 ATF1 ZFP64 ARID4B SIN3A ZNF2 GLIS2 ZNF143 ZNF207 LOC642846 A2MP1 DDX12P LINC02367 GC12M009286
GH12H010360 1.6 FANTOM5 ENCODE dbSUPER 16.5 -916.0 -916011 7 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 ZNF143 SP3 REST LOC101928100 KLRK1 DDX12P ENSG00000213443 KLRA1P LOC255308 ENSG00000257027 ENSG00000256682 CLEC2D ENSG00000255958
GH12H009272 0.9 ENCODE 26 +174.8 174819 1 TBP FEZF1 BRCA1 RFX5 ZNF366 RCOR1 FOS SMARCC1 CEBPB ZEB2 DDX12P LOC642846 GC12P009275 ENSG00000256427
GH12H010384 1.4 FANTOM5 ENCODE dbSUPER 15.3 -939.2 -939210 5 TBP FOXA2 ZSCAN4 FEZF1 ZEB1 GTF3C2 FOS ZNF362 YY2 CEBPB TAS2R19 TAS2R31 KLRA1P TAS2R14 TAS2R10 TAS2R15P MAGOHB TAS2R20 TAS2R43 KLRC3
GH12H008617 1.4 FANTOM5 Ensembl ENCODE 15.3 +829.3 829336 2 PKNOX1 JUN BMI1 CEBPG BATF FOSL1 GTF3C2 ATF7 RUNX3 IKZF2 CLEC4E LOC642846 DDX12P M6PR LINC00612 ENSG00000255753 A2ML1 A2ML1-AS2 CLEC6A CLEC4A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around DDX12P on UCSC Golden Path with GeneCards custom track

Promoters for DDX12P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000267113 129 1801 HDGF PKNOX1 ZFP64 ARID4B SIN3A ZNF2 TCF12 GLIS2 ZNF143 KLF7

Genomic Location for DDX12P Gene

Chromosome:
12
Start:
9,417,691 bp from pter
End:
9,448,229 bp from pter
Size:
30,539 bases
Orientation:
Minus strand

Genomic View for DDX12P Gene

Genes around DDX12P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DDX12P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DDX12P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DDX12P Gene

Proteins for DDX12P Gene

  • Protein details for DDX12P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q92771-DDX12_HUMAN
    Recommended name:
    Putative ATP-dependent RNA helicase DDX12
    Protein Accession:
    Q92771

    Protein attributes for DDX12P Gene

    Size:
    950 amino acids
    Molecular mass:
    106006 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DDX12P Gene

Selected DME Specific Peptides for DDX12P Gene

Q92771:
  • INDFLFQSQ
  • SRTHSQL
  • RKKIFQEPK
  • DNINLFKVQRY
  • VGGKMSE
  • VGMPFPN
  • LPYQMLL
  • MLLHAATRQAAGIRLQ
  • AVNQSIGR
  • FLAALTTANQDGRVI
  • SEGINFSD
  • PFPNIRSA
  • EAGKIGI
  • KRLKAKNLMY
  • SCGHVIP
  • AGGTMQP
  • LGRCVVMVGMP
  • IGRAIRH
  • YGKRLKA
  • RLVSLGSRQ
  • KQILYLLEKFVAVLGGN
  • TQSLSQTG
  • AQLVVLP
  • IDEAHNL
  • LVLAEYESDEE
  • SRKLFGFTE
  • FVQKKEERDLV
  • ESPTGTGK
  • CPFYNHEQM

Post-translational modifications for DDX12P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for DDX12P Gene

Gene Families for DDX12P Gene

Suggested Antigen Peptide Sequences for DDX12P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q92771

UniProtKB/Swiss-Prot:

DDX12_HUMAN :
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
Family:
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
genes like me logo Genes that share domains with DDX12P: view

Function for DDX12P Gene

Molecular function for DDX12P Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + H(2)O = ADP + phosphate.
UniProtKB/Swiss-Prot Function:
DNA helicase involved in cellular proliferation. Probably required for maintaining the chromosome segregation (By similarity).

Enzyme Numbers (IUBMB) for DDX12P Gene

Phenotypes From GWAS Catalog for DDX12P Gene

Gene Ontology (GO) - Molecular Function for DDX12P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003723 RNA binding IEA --
GO:0004003 ATP-dependent DNA helicase activity IEA --
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with DDX12P: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for DDX12P
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DDX12P Gene

Localization for DDX12P Gene

Subcellular locations from UniProtKB/Swiss-Prot for DDX12P Gene

Gene Ontology (GO) - Cellular Components for DDX12P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with DDX12P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for DDX12P Gene

Pathways & Interactions for DDX12P Gene

SuperPathways for DDX12P Gene

No Data Available

Interacting Proteins for DDX12P Gene

Selected Interacting proteins: Q92771-DDX12_HUMAN for DDX12P Gene via IID

Gene Ontology (GO) - Biological Process for DDX12P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process IEA --
GO:0007049 cell cycle IEA --
GO:0032508 DNA duplex unwinding IEA --
genes like me logo Genes that share ontologies with DDX12P: view

No data available for Pathways by source and SIGNOR curated interactions for DDX12P Gene

Drugs & Compounds for DDX12P Gene

(3) Drugs for DDX12P Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
ATP Nutra Agonist 0

(1) Additional Compounds for DDX12P Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with DDX12P: view

Transcripts for DDX12P Gene

mRNA/cDNA for DDX12P Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DDX12P Gene

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for DDX12P
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for DDX12P Gene

No ASD Table

Relevant External Links for DDX12P Gene

GeneLoc Exon Structure for
DDX12P
ECgene alternative splicing isoforms for
DDX12P

Expression for DDX12P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DDX12P Gene

NURSA nuclear receptor signaling pathways regulating expression of DDX12P Gene:

DDX12P

SOURCE GeneReport for Unigene cluster for DDX12P Gene:

Hs.504688

mRNA Expression by UniProt/SwissProt for DDX12P Gene:

Q92771-DDX12_HUMAN
Tissue specificity: Only expressed in proliferating tissues.
genes like me logo Genes that share expression patterns with DDX12P: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DDX12P Gene

Orthologs for DDX12P Gene

Evolution for DDX12P Gene

ENSEMBL:
Gene Tree for DDX12P (if available)
TreeFam:
Gene Tree for DDX12P (if available)

No data available for Orthologs for DDX12P Gene

Paralogs for DDX12P Gene

(3) SIMAP similar genes for DDX12P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DDX12P: view

No data available for Paralogs for DDX12P Gene

Variants for DDX12P Gene

Sequence variations from dbSNP and Humsavar for DDX12P Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000036198 -- 9,448,898(+) TTCCC(A/C)GCAGG intron-variant, upstream-variant-2KB
rs1000377675 -- 9,430,535(+) CATCC(A/G)AGTCC intron-variant
rs1000715437 -- 9,423,678(+) TGACC(A/G)GGCCA intron-variant
rs1000768130 -- 9,423,844(+) AGCAC(C/T)GCTTC intron-variant
rs1000996183 -- 9,434,831(+) CGAGT(A/G)AACAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DDX12P Gene

Variant ID Type Subtype PubMed ID
dgv2344n54 CNV gain 21841781
dgv761n106 OTHER inversion 24896259
esv2568009 CNV loss 19546169
esv2759878 CNV gain+loss 17122850
esv2760270 CNV gain+loss 21179565
esv2760977 CNV loss 21179565
esv3580099 CNV loss 25503493
esv3628503 CNV loss 21293372
esv3628504 CNV gain 21293372
esv3628505 CNV gain 21293372
nsv1035958 CNV gain 25217958
nsv1050161 CNV loss 25217958
nsv1051530 CNV gain 25217958
nsv1128662 CNV duplication 24896259
nsv1141210 CNV duplication 24896259
nsv1159969 CNV duplication 26073780
nsv428271 CNV gain 18775914
nsv508665 CNV deletion 20534489
nsv509454 CNV insertion 20534489
nsv557367 CNV loss 21841781
nsv557368 CNV loss 21841781
nsv557385 CNV loss 21841781
nsv557387 CNV gain 21841781
nsv7228 OTHER inversion 18451855
nsv8907 CNV gain 18304495
nsv952799 CNV deletion 24416366
nsv975443 CNV duplication 23825009
nsv983275 CNV duplication 23825009

Relevant External Links for DDX12P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DDX12P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DDX12P Gene

Disorders for DDX12P Gene

Relevant External Links for DDX12P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DDX12P

No disorders were found for DDX12P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DDX12P Gene

Publications for DDX12P Gene

  1. Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1. (PMID: 9013641) Amann J … Lahti JM (The Journal of biological chemistry 1997) 3 4 60
  2. Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation. (PMID: 17611414) Inoue A … Lahti JM (Cell cycle (Georgetown, Tex.) 2007) 22 60
  3. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4 60
  4. Lineage-specific gene duplication and loss in human and great ape evolution. (PMID: 15252450) Fortna A … Sikela JM (PLoS biology 2004) 3 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for DDX12P Gene

Sources for DDX12P Gene

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