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Aliases for DDX11L8 Gene

Aliases for DDX11L8 Gene

  • DEAD/H-Box Helicase 11 Like 8 2 3 5
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 Like 8 2
  • DEAD/H (Asp-Glu-Ala-Asp/His) Box Helicase 11 Like 8 2
  • DEAD/H Box Protein 11-Like 8 4
  • EC 3.6.4.13 4

External Ids for DDX11L8 Gene

Previous GeneCards Identifiers for DDX11L8 Gene

  • GC00U928076
  • GC12P000091
  • GC12M000095

Summaries for DDX11L8 Gene

GeneCards Summary for DDX11L8 Gene

DDX11L8 (DEAD/H-Box Helicase 11 Like 8) is a Pseudogene.

UniProtKB/Swiss-Prot for DDX11L8 Gene

  • Putative DNA helicase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DDX11L8 Gene

Genomics for DDX11L8 Gene

Regulatory Elements for DDX11L8 Gene

Enhancers for DDX11L8 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F000989 1 ENCODE 16.2 +978.6 978552 4.4 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 SP3 SP5 ENSG00000255825 DDX11L8 ENSG00000261799 ENSG00000250132 ERC1 WNT5B RAD52
GH12F000386 0.2 ENCODE 16.2 +376.2 376184 4.0 PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 CCDC77 ENSG00000250132 ENSG00000255825 DDX11L8 KDM5A ENSG00000261799 PIR47780
GH12F000641 0.6 ENCODE 16.2 +632.4 632381 5.9 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 LOC100049716 ENSG00000255825 DDX11L8 LOC100288778 KDM5A WNK1 LOC105369595 NINJ2 GC12P000646 PIR35680
GH12F000749 1.3 FANTOM5 ENCODE 16.2 +740.3 740333 7.0 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 KDM5A ENSG00000255825 DDX11L8 ENSG00000261799 LOC100288778 RAD52 NINJ2 CCDC77 WNK1 GC12M000753
GH12F000012 0.7 Ensembl ENCODE 0.8 +1.2 1191 1.4 PKNOX1 FEZF1 ZIC2 ZFHX2 GATA3 GLIS2 ZBTB48 PRDM10 FOS ZNF600 DDX11L8 LOC100288778
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around DDX11L8 on UCSC Golden Path with GeneCards custom track

Genomic Location for DDX11L8 Gene

Chromosome:
12
Start:
12,310 bp from pter
End:
14,520 bp from pter
Size:
2,211 bases
Orientation:
Plus strand

Genomic View for DDX11L8 Gene

Genes around DDX11L8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DDX11L8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DDX11L8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DDX11L8 Gene

Proteins for DDX11L8 Gene

  • Protein details for DDX11L8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MPP1-D11L8_HUMAN
    Recommended name:
    Putative ATP-dependent RNA helicase DDX11-like protein 8
    Protein Accession:
    A8MPP1

    Protein attributes for DDX11L8 Gene

    Size:
    907 amino acids
    Molecular mass:
    101811 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DDX11L8 Gene

Post-translational modifications for DDX11L8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DDX11L8 Gene

Domains & Families for DDX11L8 Gene

Suggested Antigen Peptide Sequences for DDX11L8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MPP1

UniProtKB/Swiss-Prot:

D11L8_HUMAN :
  • Contains 1 helicase ATP-binding domain.
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
Domain:
  • Contains 1 helicase ATP-binding domain.
Family:
  • Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
genes like me logo Genes that share domains with DDX11L8: view

No data available for Gene Families for DDX11L8 Gene

Function for DDX11L8 Gene

Molecular function for DDX11L8 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + H(2)O = ADP + phosphate.
UniProtKB/Swiss-Prot Function:
Putative DNA helicase.

Enzyme Numbers (IUBMB) for DDX11L8 Gene

Animal Model Products

No data available for Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DDX11L8 Gene

Localization for DDX11L8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DDX11L8 Gene

Nucleus, nucleolus.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DDX11L8 Gene

Pathways & Interactions for DDX11L8 Gene

SuperPathways for DDX11L8 Gene

No Data Available

Interacting Proteins for DDX11L8 Gene

Selected Interacting proteins: A8MPP1-D11L8_HUMAN for DDX11L8 Gene via UniProtKB IID

Gene Ontology (GO) - Biological Process for DDX11L8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DDX11L8 Gene

Drugs & Compounds for DDX11L8 Gene

(3) Drugs for DDX11L8 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
Adenosine triphosphate Approved Nutra 0

(1) Additional Compounds for DDX11L8 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with DDX11L8: view

Transcripts for DDX11L8 Gene

mRNA/cDNA for DDX11L8 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for DDX11L8 Gene

No ASD Table

Relevant External Links for DDX11L8 Gene

GeneLoc Exon Structure for
DDX11L8
ECgene alternative splicing isoforms for
DDX11L8

Expression for DDX11L8 Gene

mRNA expression in normal human tissues for DDX11L8 Gene

mRNA differential expression in normal tissues according to GTEx for DDX11L8 Gene

This gene is overexpressed in Testis (x21.0), Whole Blood (x16.3), Small Intestine - Terminal Ileum (x5.5), Brain - Cerebellum (x5.2), and Brain - Cerebellar Hemisphere (x4.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DDX11L8 Gene



NURSA nuclear receptor signaling pathways regulating expression of DDX11L8 Gene:

DDX11L8
genes like me logo Genes that share expression patterns with DDX11L8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for DDX11L8 Gene

Orthologs for DDX11L8 Gene

Evolution for DDX11L8 Gene

ENSEMBL:
Gene Tree for DDX11L8 (if available)
TreeFam:
Gene Tree for DDX11L8 (if available)

No data available for Orthologs for DDX11L8 Gene

Paralogs for DDX11L8 Gene

(6) SIMAP similar genes for DDX11L8 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with DDX11L8: view

No data available for Paralogs for DDX11L8 Gene

Variants for DDX11L8 Gene

Relevant External Links for DDX11L8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DDX11L8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for DDX11L8 Gene

Disorders for DDX11L8 Gene

No disorders were found for DDX11L8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for DDX11L8 Gene

Publications for DDX11L8 Gene

  1. DDX11L: a novel transcript family emerging from human subtelomeric regions. (PMID: 19476624) Costa V. … Ciccodicola A. (BMC Genomics 2009) 2 3 64
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for DDX11L8 Gene

Sources for DDX11L8 Gene

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