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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DDX10 Gene

protein-coding   GIFtS: 57
GCID: GC11P108569

DEAD (Asp-Glu-Ala-Asp) box polypeptide 10

(Previous name: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase)...)
 Explore 6 diseases affiliated with
DDX10 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DDX10    

Aliases
for DDX10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 101 2     DEAD Box-102
HRH-J81 2     Probable ATP-Dependent RNA Helicase DDX102
DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 10 (RNA Helicase)1 2     EC 3.6.4.133
DEAD Box Protein 102 3     EC 3.6.18
DDX10-NUP98 Fusion Protein Type 22     

External Ids:    HGNC: 27351   Entrez Gene: 16622   Ensembl: ENSG000001781057   OMIM: 6012355   UniProtKB: Q132063   

Export aliases for DDX10 gene to outside databases

Previous GC identifers: GC11P110792 GC11P109988 GC11P108073 GC11P108041 GC11P104461


Summaries
for DDX10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DDX10:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation
initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution
patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular
growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this
gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with
de novo or therapy-related myeloid malignancies. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DDX10_HUMAN, Q13206
Function: Putative ATP-dependent RNA helicase

Gene Wiki entry for DDX10


Genomic Views
for DDX10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DDX10 gene promoter:
         Pax-5   Tal-1   FOXD3   Nkx2-5   GATA-1   E47   CREB   POU2F1   POU2F1a   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DDX10 promoter sequence
   Search SABiosciences Chromatin IP Primers for DDX10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDX10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q22-q23   Ensembl cytogenetic band:  11q22.3   HGNC cytogenetic band: 11q22-q23

DDX10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DDX10 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P108569:  view genomic region     (about GC identifiers)

Start:
 108,535,752 bp from pter      End:
 108,811,657 bp from pter
Size:
 275,906 bases      Orientation:
 plus strand

Proteins
for DDX10 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DDX10_HUMAN, Q13206 (See protein sequence)
Recommended Name: Probable ATP-dependent RNA helicase DDX10  
Size: 875 amino acids; 100888 Da
1 PDB 3D structure from and Proteopedia for DDX10:
2PL3 (3D)    
Secondary accessions: B2RCQ3 Q5BJD8

Explore the universe of human proteins at neXtProt for DDX10: NX_Q13206

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13206

    • 4/10 DME Specific Peptides for DDX10 (Q13206) (see all 10)
     DLARLSL  DEADRIL  SPTRELA  IISPTREL 

    DDX10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004389.2  
    ENSEMBL proteins: 
     ENSP00000314348   ENSP00000432032  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: DDX10
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    Novus Biologicals DDX10 Protein
    Novus Biologicals DDX10 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DDX10


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    Uscn ELISAs and CLIAs for DDX10

    Protein Domains /
    Families
    for DDX10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DDX10 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR014014 RNA_helicase_DEAD_Q_motif
     IPR025313 DUF4217
     IPR000629 RNA-helicase_DEAD-box_CS
     IPR014001 Helicase_ATP-bd

    Graphical View of Domain Structure for InterPro Entry Q13206

    ProtoNet protein and cluster: Q13206

    1 Blocks protein family: IPB000629 ATP-dependent helicase

    UniProtKB/Swiss-Prot: DDX10_HUMAN, Q13206
    Domain: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding
    and hydrolysis
    Similarity: Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain


    Function
    for DDX10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DDX10_HUMAN, Q13206
    Function: Putative ATP-dependent RNA helicase
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Genatlas biochemistry entry for DDX10:
    DEAD/H box protein 10,ubiquitously expressed,fused with NUP98 in de novo or therapy related myeloid maligancies with
    inv 11(p15-q22)

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.131

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DDX10
    1 QIAGEN miScript miRNA Assays for microRNA that regulate DDX10:
    hsa-miR-1266
    SwitchGear 3'UTR luciferase reporter plasmid: DDX10 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX10 (see all 7)
    OriGene shRNA RFP: DDX10
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    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DDX10

    Clone
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    Search LifeMap BioReagents cell lines for DDX10

    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0003724RNA helicase activity TAS8660968
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--


    DDX10 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for DDX10:
     Decreased p24 protein expressi  Nucleolar pre-40S maturation d 

    Animal Models:
         1 MGI phenotypic allele for Ddx10 (no phenotypes)

    DDX10 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for DDX10 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DDX10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/141 Interacting proteins for DDX10 (Q132063 ENSP000003143484) via UniProtKB, MINT, STRING, and/or I2D (see all 141)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Drugs & Compounds
    for DDX10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DDX10
    Search CenterWatch for drugs/clinical trials and news about DDX10 

    Transcripts
    for DDX10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DDX10 gene: 
    NM_004398.2  

    Unigene Cluster for DDX10:

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
    Hs.591931  [show with all ESTs]
    Unigene Representative Sequence: AB209884
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322536(uc001pkm.3) ENST00000534774 ENST00000526794(uc001pkl.1)
    ENST00000534439 ENST00000533198 ENST00000530116 ENST00000524979 ENST00000534221


    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate DDX10:
    hsa-miR-1266
    SwitchGear 3'UTR luciferase reporter plasmid: DDX10 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDX10 (see all 7)
    OriGene shRNA RFP: DDX10
    OriGene siRNA: DDX10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDX10
    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDX10

    Additional cDNA sequence: 

    AB000267.1 AB001343.1 AB040537.1 AB209884.1 AK296752.1 AK315216.1 AL833534.1 BC049217.1 
    BC064921.1 BC091521.1 BC093654.1 BC093656.1 U28042.1 

    5 DOTS entries:

    DT.310453  DT.97799397  DT.100782442  DT.100782435  DT.100736227 

    24/105 AceView cDNA sequences (see all 105):

    NM_004398 AL043665 BX489177 AI758573 BU159235 BU170172 AL705075 BQ941659 
    CD654730 BX283469 BQ928472 CA429323 BU619096 BC049217 AI376353 AB040537 
    AA604373 AA809921 BF934536 BU159524 BC064921 BM561644 CB163252 BU616591 

    GeneLoc Exon Structure


    Expression
    for DDX10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DDX10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTTCGACGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DDX10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DDX10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DDX10

    SOURCE GeneReport for Unigene cluster: Hs.591931

    UniProtKB/Swiss-Prot: DDX10_HUMAN, Q13206
    Tissue specificity: High in testis but widely expressed

        SABiosciences Custom PCR Arrays for DDX10
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    In Situ
    Assay Products:     
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    Orthologs
    for DDX10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DDX10 gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves DDX101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 70.5(n)
    67.94(a)    		   418965  NM_001079725.1  NP_001073193.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DDX106
    		 --
    		 81(a)
    		 1 ↔ 1
    		 5(125140627-125208821)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.146812 Xenopus laevis transcribed sequence with moderate similarity more 78.49(n)    48050676 
    zebrafish
    (Danio rerio)    		 Actinopterygii BM071107.12   -- 70.44(n)    BM071107.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG58001 , 3 RNA helicase3
    CG58001    		 51(a)
    (best of 2)3
    52.51(n)1
    48.34(a)1    		   16B103
    327421  NM_133002.11  NP_573230.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y23H5B.61 , 3 Protein Y23H5B.61 52(a)
    (best of 2)3
    53.05(n)1
    45.9(a)1    		   I(2489985-2497262)3
    1718101  NM_058588.31  NP_490989.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes HCA4(YJL033W)4
    HCA41    		 Putative nucleolar DEAD box RNA helicase; high-copy more4
    Hca4p1    		 51.88(n)1
    44.23(a)1    		   10(383837-386149)4
    8534191, 4  NP_012501.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G549101 DEAD-box ATP-dependent RNA helicase 32 53.36(n)
    44.53(a)    		   835582  NM_124873.2  NP_200302.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.247082 Oryza sativa (japonica cultivar-group) cDNA clone0 more 71.32(n)    NM_187400.1 


    ENSEMBL Gene Tree for DDX10 (if available)
    TreeFam Gene Tree for DDX10 (if available) 

    Paralogs
    for DDX10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DDX10 gene
    16 SIMAP similar genes for DDX10 using alignment to 3 protein entries:     DDX10_HUMAN (see all proteins):
    DDX18    DDX54    DDX39B    DDX56    DDX55    E4-DBP
    DDX47    DDX59    EIF4A2    DDX6    EIF4A1    MST162
    DKFZp547B159    EIF4A3    DKFZp564G1016    DDX49

    DDX10 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for DDX10
    PGOHUM00000262839 PGOHUM00000258384


    Genomic Variants
    for DDX10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4232 NCBI SNPs in DDX10 are shown (see all 4232)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs730017411,2
    		C,F,--108533980(+) CATTTT/AAGCCA 1 -- us2k12Minor allele frequency- A:0.17NA EA 240
    rs1445454021,2
    		C,--108534138(+) TACTT-/TCTC  
                TATTA     		1 -- us2k10--------
    rs2009440871,2
    		C--108534141(-) TAATAA/GANNNN 1 -- us2k10--------
    rs798516271,2
    		C,--108534222(+) TTCACT/GTAGCT 1 -- us2k12Minor allele frequency- G:0.18WA 120
    rs1881848891,2
    		--108534365(+) GCTTCC/TACATT 1 -- us2k10--------
    rs118216181,2
    		H--108534374(+) ttttaA/Gctata 1 -- us2k10--------
    rs1810874651,2
    		--108534387(+) GCTGTA/GGTGAA 1 -- us2k10--------
    rs118240311,2
    		H--108534398(+) cacggG/Tatgca 1 -- us2k1 tfbs30--------
    rs38583991,2
    		C,A,--108534440(+) GCTATG/ACATAC 1 -- us2k13Minor allele frequency- A:0.18NA EA 242
    rs38584001,2
    		C,F,A,H,--108534560(+) AGTGTT/CCCTGA 1 -- us2k118Minor allele frequency- C:0.13NS EA NA 2402

    HapMap Linkage Disequilibrium report for DDX10 (108535752 - 108785752 bp, first 250kb of DDX10)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for DDX10
         4 CNVs: 4761 86029 66066 5646

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDX10
    DNA2.0 Custom Variant and Variant Library Synthesis for DDX10

    Disorders / Diseases
    for DDX10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DDX10 for disorders           About GeneDecksing

    OMIM gene information: 601235    OMIM disorders: --

    6 diseases for DDX10:    About MalaCards
    myeloid malignancy    myelodysplastic syndrome    acute myeloid leukemia    myeloid leukemia
    leukemia    malaria

    1 Novoseek disease relationship for DDX10 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    myelodysplastic syndromes 51.9 1 10830185 (1)

    Human Genome Epidemiology (HuGE) Navigator: DDX10 (1 document)

    Export disorders for DDX10 gene to outside databases

    Publications
    for DDX10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DDX10 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with DDX10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23. (PubMed id 8660968)1, 2, 3 Savitsky K.... Rotman G. (1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10. (PubMed id 9166830)1, 9 Arai Y....Ohki M. (1997)
    4. Fusion of the nucleoporin gene, NUP98, and the putative RNA helicase gene, DDX10, by inversion 11 (p15q22) chromosome translocation in a patient with etoposide-related myelodysplastic syndrome. (PubMed id 10830185)1, 9 Nakao K....Ohki M. (2000)
    5. The inv(11)(p15q22) chromosome translocation of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts. (PubMed id 10222653)1, 9 Ikeda T....Takahara J. (1999)
    6. Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
    7. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    External Searches for DDX10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing DDX10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1662 HGNC: 2735 AceView: DDX10 Ensembl:ENSG00000178105 euGenes: HUgn1662
    ECgene: DDX10 H-InvDB: DDX10

    Other Databases showing DDX10 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DDX10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DDX10 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DDX10 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for DDX10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DDX10 gene:
    Search GeneIP for patents involving DDX10

    GeneCards and IP:
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