Aliases for DDRGK1 Gene
External Ids for DDRGK1 Gene
Previous Symbols for DDRGK1 Gene
GeneCards Summary for DDRGK1 Gene
DDRGK1 (DDRGK Domain Containing 1) is a Protein Coding gene.
UniProtKB/Swiss-Prot for DDRGK1 Gene
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity).