Aliases for DDRGK1 Gene
External Ids for DDRGK1 Gene
Previous HGNC Symbols for DDRGK1 Gene
Previous GeneCards Identifiers for DDRGK1 Gene
GeneCards Summary for DDRGK1 Gene
DDRGK1 (DDRGK Domain Containing 1) is a Protein Coding gene.
UniProtKB/Swiss-Prot for DDRGK1 Gene
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498). May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity).