DDAH2 Gene
protein-coding GIFtS: 56
GCID: GC06M031694
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|
dimethylarginine dimethylaminohydrolase 2
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Aliases
for DDAH2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Dimethylarginine Dimethylaminohydrolase 21 2 3 | | G6a2 | | Protein G6a2 3 | | Alternative Name: NG30, G6a2 | | DDAH2 3 | | Dimethylargininase-23 | | DDAH-22 3 | | Dimethylarginine Dimethylaminohydrolase II2 | | DDAHII2 3 | | N(G),N(G)-Dimethylarginine Dimethylaminohydrolase 22 | | NG302 3 | | NG-Dimethylarginine Dimethylamino Hydrolase Homolog2 | | S-Phase Protein2 3 | | Dimethylargininase-23 | | EC 3.5.3.183 8 | | G6A3 |
Export aliases for DDAH2 gene to outside databasesPrevious GC identifers: GC06M031758 GC06M031465 GC06M031799 GC06M031803 GC06M031481 |
Summaries
for DDAH2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DDAH2:
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role innitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxidesynthase activity. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: DDAH2_HUMAN, O95865Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitorsof NOS. Has therefore a role in the regulation of nitric oxide generation
|
Genomic Views
for DDAH2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1
- NT_167249.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DDAH2 gene promoter:
AREB6 Sp1 p53
Other transcription factors
Search SABiosciences Chromatin IP Primers for DDAH2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDAH2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.33 HGNC cytogenetic band: 6p21DDAH2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M031694: view genomic region
(about GC identifiers)
Start:
|
31,694,815 bp from pter |
End:
|
31,698,394 bp from pter |
Size:
|
3,580 bases |
Orientation:
|
minus strand |
6 alternative locations:
| Chr6-,ALT_REF_LOCI_5 31,685,923-31,689,145 | Chr6-,ALT_REF_LOCI_3 31,676,987-31,691,249 | Chr6-,ALT_REF_LOCI_6 31,685,048-31,723,853 | | Chr6-,ALT_REF_LOCI_4 31,657,366-31,660,588 | Chr6-,ALT_REF_LOCI_2 31,682,228-31,724,640 | Chr6-,ALT_REF_LOCI_7 31,615,099-31,618,321 | |
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Proteins
for DDAH2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DDAH2_HUMAN, O95865 (See
protein sequence)Recommended Name: N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 Size: 285 amino acids; 29644 Da
Subcellular location: Cytoplasm. Mitochondrion. Note=Translocates from cytosol to mitochondrion upon IL-1betastimulation in chondrocytes
Secondary accessions: A2BEZ7Explore the universe of human proteins at neXtProt for DDAH2: NX_O95865
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95865
4/5 DME Specific Peptides for DDAH2 (O95865) (see all 5)
DDAH2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_039268.1
ENSEMBL proteins: ENSP00000413164 ENSP00000364945 ENSP00000364943 ENSP00000364949 ENSP00000397466 ENSP00000395759
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
DDAH2 for ontologies About GeneDecksing
DDAH2 Antibody Products:
Assay Products for DDAH2: |
Protein
Domains /
Families
for DDAH2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DDAH2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O95865ProtoNet protein and cluster: O95865 1 Blocks protein family: IPB003198 Amidinotransferase
UniProtKB/Swiss-Prot: DDAH2_HUMAN, O95865Similarity: Belongs to the DDAH family |
Function
for DDAH2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: DDAH2_HUMAN, O95865Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitorsof NOS. Has therefore a role in the regulation of nitric oxide generationCatalytic activity: N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline Genatlas biochemistry entry for DDAH2:N-omega,N-omega dimethylarginine dimethylaminohydrolase,endogenous inhibitor of nitric oxide synthesis,encoded byG6A,member of MHC3
Enzyme Number (IUBMB): EC 3.5.3.181 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DDAH2 (NM_013974) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DDAH2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDAH2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDAH2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
DDAH2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for DDAH2:
Animal Models:
Mouse knock-out Ddah2tm1Roab for DDAH2
1 MGI mutant phenotype (inferred from 2 alleles ) (MGI details for Ddah2):
DDAH2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DDAH2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DDAH2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/23 Interacting proteins for DDAH2 (O958651, 2, 3 ENSP000003649434) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
DDAH2 for ontologies About GeneDecksing
|
Drugs & Compounds
for DDAH2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
DDAH2 for compounds About GeneDecksing
 Browse Tocris compounds for DDAH2
4 HMDB Compounds for DDAH2 About this table
1 DrugBank Compound for DDAH2 About this table
10/26 Novoseek chemical compound relationships for DDAH2 gene (see all 26) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| adma |
97.5 |
272 |
20209122 (8), 17141242 (6), 18342305 (6), 16897158 (5) (see all 91) |
| demethylbellidifolin |
85.3 |
2 |
15234768 (1) |
| n(g),n(g)-dimethylarginine |
84.8 |
3 |
16472125 (1), 8982498 (1), 19682580 (1) |
| dimethylamine |
82.8 |
7 |
19682581 (1), 16702618 (1), 14664899 (1), 11168975 (1) (see all 7) |
| citrulline |
80.8 |
18 |
17205823 (2), 17653133 (2), 10377069 (1), 8982498 (1) (see all 15) |
| nitric oxide |
77.8 |
91 |
18167189 (6), 12370443 (6), 18342305 (5), 17097077 (3) (see all 34) |
| arginine |
74 |
26 |
17075694 (2), 11473257 (2), 16897158 (1), 16358064 (1) (see all 19) |
| 2,4-dichlorophenoxyacetic acid |
73 |
10 |
18292189 (2), 17977009 (1), 19178698 (1), 14664899 (1) (see all 6) |
| xanthone |
63.2 |
3 |
14604680 (2) |
| lysophosphatidylcholine |
53.7 |
15 |
18342305 (4), 16309971 (3), 16897158 (1), 12750878 (1) |
Search CenterWatch for drugs/clinical trials and news about DDAH2
|
Transcripts
for DDAH2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DDAH2 gene: NM_013974.1 Unigene Cluster for DDAH2: Dimethylarginine dimethylaminohydrolase 2 Hs.247362 [show with all ESTs]Unigene Representative Sequence: BM46079510 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000437288 ENST00000469963 ENST00000375789(uc003nwp.3) ENST00000480913
ENST00000483792 ENST00000375787 ENST00000375792(uc003nwq.3) ENST00000416410
ENST00000436437 ENST00000488119
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DDAH2 (NM_013974) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DDAH2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDAH2 |
Additional cDNA sequence: AF070667.1 AF087894.1 AK026191.1 AK098671.1 AK310024.1 BC001435.2 13 DOTS entries: DT.100820948 DT.100820945 DT.448917 DT.100820947 DT.102841783 DT.95153733 DT.97768715 DT.100820952 DT.121408303 DT.91769251 DT.121408228 DT.91769254 DT.91769255 24/1684 AceView cDNA sequences (see all 1684): CB145310 CB143872 AL544481 CA445481 BG747632 CN484722 BM707924 CN485048 AI971375 BM562536 BU186790 BU846299 BM837110 BU688148 BM854112 BU627466 BQ441647 CB123776 BF515233 AI352543 BG397220 BM841373 BP371770 CA306475
GeneLoc Exon Structure
|
Expression
for DDAH2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DDAH2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGGGACCTC
About this image
See DDAH2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DDAH2
SOURCE GeneReport for Unigene cluster: Hs.247362
UniProtKB/Swiss-Prot: DDAH2_HUMAN, O95865Tissue specificity: Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very lowlevels in brain
SABiosciences Expression via Pathway-Focused PCR Arrays including DDAH2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDAH2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DDAH2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDAH2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDAH2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDAH2 |
Orthologs
for DDAH2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for DDAH2 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for DDAH2 (if available)
TreeFam Gene Tree for DDAH2 (if available) |
Paralogs
for DDAH2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DDAH2 gene
- DDAH12
1 SIMAP similar gene for DDAH2 using alignment to 5 protein entries: DDAH2_HUMAN (see all proteins):DDAH1
DDAH2 for paralogs About GeneDecksing
|
Genomic Variants
for DDAH2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DDAH2 (31694815 - 31698394 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for DDAH2
2 Indels: 12829 12828
Human Gene Mutation Database (HGMD): DDAH2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDAH2 |
|
Disorders
/ Diseases
for DDAH2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DDAH2 for disorders About GeneDecksing
OMIM gene information: 604744
OMIM disorders: --
20/21  diseases for DDAH2 (see all 21): About MalaCardsasphyxiating thoracic dystrophy pre-eclampsia systemic lupus erythematosus lupus erythematosus
cytomegalovirus infection diabetes mellitus hypercholesterolemia essential hypertension
eclampsia pulmonary hypertension hypertension arteriosclerosis
kidney disease atherosclerosis hyperglycemia homocysteine
breast cancer cerebritis hypoxia hepatitis
10/11 Novoseek disease relationships for DDAH2 gene (see all 11) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cardiovascular diseases |
51.6 |
2 |
14550280 (1), 20219849 (1) |
| atherosclerosis |
41 |
2 |
17293168 (1), 18991678 (1), 17368960 (1) |
| preeclampsia |
35.6 |
11 |
18251679 (3), 19570459 (2), 15501905 (1), 16508323 (1) |
| renal failure chronic |
33.3 |
1 |
16932427 (1) |
| diabetes mellitus |
18.4 |
3 |
19775692 (2) |
| necrosis |
18.2 |
4 |
10377069 (1), 14604680 (1), 14750034 (1), 11168975 (1) |
| hypercholesterolemia |
11.5 |
2 |
10377069 (1), 17293168 (1) |
| stroke |
0 |
1 |
19250061 (1) |
| hypertension pulmonary |
0 |
2 |
12615801 (1), 15827267 (1) |
| tumors |
0 |
4 |
10377069 (1), 14604680 (1), 14750034 (1), 11168975 (1) |
Human Genome Epidemiology (HuGE) Navigator: DDAH2 (14 documents)
Export disorders for DDAH2 gene to outside databases
|
Publications
for DDAH2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DDAH2 gene, integrated from 9 sources (see all 141):
(articles sorted by number of sources associating them with DDAH2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. (PubMed id 10493931)1, 2, 3, 9 Leiper J.M.... Vallance P. (1999)
- Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. (PubMed id 10950934)1, 7, 9 Tran C.T....Leiper J.M. (2000)
- Dimethylarginine dimethylaminohydrolase 2, a newly ide ntified mitochondrial protein modulating nitric oxide synthesis in normal human chondrocytes. (PubMed id 21898353)1, 2 Cillero-Pastor B....Blanco F.J. (2012)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region. (PubMed id 10384126)1, 2 Ribas G.... Campbell R.D. (1999)
- Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine. (PubMed id 18342305)1, 9 Feng M....Xiong Y. (2008)
- Common genetic variation in DDAH2 is associated with intracerebral hemorrhage in Chinese population: a multicenter case-control study in China. (PubMed id 19250061)1, 9 Bai Y....Hui R. (2009)
|
External Searches for DDAH2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DDAH2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DDAH2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DDAH2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DDAH2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DDAH2 gene:
Search GeneIP for patents involving DDAH2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DDAH2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for DDAH2 | | OriGene shRNA RFP for DDAH2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DDAH2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DDAH2 | | | OriGene Protein Over-expression Lysate for DDAH2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DDAH2 | | OriGene 3'-UTR Clone for DDAH2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DDAH2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DDAH2 | | OriGene Custom Protein Services for DDAH2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DDAH2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DDAH2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DDAH2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DDAH2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DDAH2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DDAH2 |
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| | | | Search Tocris compounds for DDAH2 |
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 | | | DDAH2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DDAH2 |
|  |  |  | | | | ThermoFisher Antibody for DDAH2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DDAH2 |
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