Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DCUN1D4 Gene

protein-coding GIFtS: 50
GCID: GC04P052709

DCN1, defective in cullin neddylation 1, domain containing...

Explore 2 diseases affiliated with
DCUN1D4 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
DCN1, Defective In Cullin Neddylation 1, Domain Containing 4 (S. Cerevisiae)¹ ²
KIAA0276¹ ³ ⁵
Defective In Cullin Neddylation Protein 1-Like Protein 4² ³
DCUN1 Domain-Containing Protein 4² ³
DCN1-Like Protein 4²

External Ids:	HGNC: 28998¹	Entrez Gene: 23142²	Ensembl: ENSG00000109184⁷	OMIM: 612977⁵	UniProtKB: Q92564³

Export aliases for DCUN1D4 gene to outside databases

Previous GC identifers: GC04P052551 GC04P052404 GC04P048650

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for DCUN1D4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_022853.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DCUN1D4 gene promoter:
TBP AhR ATF-2 HSF1 (long) Arnt GATA-2 RORalpha1 Ik-2 HSF1short ATF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DCUN1D4 promoter sequence

Search SABiosciences Chromatin IP Primers for DCUN1D4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCUN1D4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q12 Ensembl cytogenetic band: 4q12 HGNC cytogenetic band: 4q11

DCUN1D4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCUN1D4 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04P052709: view genomic region (about GC identifiers)

Start:	52,709,166 bp from pter	End:	52,783,003 bp from pter
Size:	73,838 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DCNL4_HUMAN, Q92564 (See protein sequence)

Recommended Name: DCN1-like protein 4

Size: 292 amino acids; 34068 Da

Sequence caution: Sequence=BAA13405.1; Type=Erroneous initiation; Sequence=CAD97912.1; Type=Erroneous initiation;

Secondary accessions: Q7Z3F3 Q7Z6B8

Alternative splicing: 2 isoforms: Q92564-1 Q92564-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCUN1D4: NX_Q92564

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q92564

DCUN1D4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001035492.1 NP_055930.2

ENSEMBL proteins:

ENSP00000425644 ENSP00000334625 ENSP00000370850 ENSP00000421127 ENSP00000425792

ENSP00000423808 ENSP00000424476 ENSP00000421699 ENSP00000426982 ENSP00000422711

ENSP00000426048 ENSP00000423794 ENSP00000389900 ENSP00000370846

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: DCUN1D4 OriGene Protein Over-expression Lysate (see all 2): DCUN1D4 OriGene Custom Protein Services for DCUN1D4
	GenScript Custom Purified and Recombinant Proteins Services for DCUN1D4
	Novus Biologicals DCUN1D4 Protein Novus Biologicals DCUN1D4 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DCUN1D4

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005634	nucleus	--	--

DCUN1D4 for ontologies About GeneDecksing

DCUN1D4 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for DCUN1D4
	GenScript Custom Superior Antibodies Services for DCUN1D4
	Novus Biologicals DCUN1D4 Antibodies
	Search for Antibodies for DCUN1D4 at Abcam
	Uscn Antibodies for DCUN1D4
	Search ThermoFisher Antibodies for DCUN1D4

Assay Products for DCUN1D4:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for DCUN1D4
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for DCUN1D4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DCUN1D4 for domains About GeneDecksing

2 InterPro domains/families:

IPR005176 PONY_dom

IPR014764 DCN-prot

Graphical View of Domain Structure for InterPro Entry Q92564

ProtoNet protein and cluster: Q92564

UniProtKB/Swiss-Prot: DCNL4_HUMAN, Q92564

Similarity: Contains 1 DCUN1 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 2): DCUN1D4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCUN1D4
		8/100 QIAGEN miScript miRNA Assays for microRNAs that regulate DCUN1D4 (see all 100):
		hsa-miR-300 hsa-miR-15a hsa-miR-128 hsa-miR-4274 hsa-miR-200b hsa-miR-3148 hsa-miR-130b hsa-miR-374b*

		SwitchGear 3'UTR luciferase reporter plasmid: DCUN1D4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCUN1D4 (see all 6) OriGene shRNA RFP: DCUN1D4 OriGene siRNA: DCUN1D4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCUN1D4

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for DCUN1D4

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): DCUN1D4 (NM_015115)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCUN1D4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCUN1D4

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DCUN1D4
		Search LifeMap BioReagents cell lines for DCUN1D4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCUN1D4

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

DCUN1D4 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for DCUN1D4:

Increased gamma-H2AX phosphory

Increased number of cells in m

Metaphase cells

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DCUN1D4

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for DCUN1D4 (Q92564³ ENSP00000334625⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
VAV2	P52735³, ENSP00000360916⁴	I2D: score=1 STRING: ENSP00000360916
UBE2M	ENSP00000253023⁴	STRING: ENSP00000253023
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

DCUN1D4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DCUN1D4
Search CenterWatch for drugs/clinical trials and news about DCUN1D4 / DCNL4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DCUN1D4 gene (2 alternative transcripts):

NM_001040402.1 NM_015115.2

Unigene Cluster for DCUN1D4:

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

Hs.605388 [show with all ESTs]

Unigene Representative Sequence: NM_001040402

18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):

ENST00000509376 ENST00000511675 ENST00000334635(uc003gze.3 uc011bzn.2 uc011bzo.2)

ENST00000381441(uc003gzf.3) ENST00000506673 ENST00000504113 ENST00000502930

ENST00000507741 ENST00000513800 ENST00000477560(uc003gzg.3 uc003gzh.3)

ENST00000509068 ENST00000505403 ENST00000504661 ENST00000504923 ENST00000510587

ENST00000507659 ENST00000505634 ENST00000510808

miRNA Products:		OriGene 3'-UTR Clone (see all 2): DCUN1D4 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCUN1D4
		8/100 QIAGEN miScript miRNA Assays for microRNAs that regulate DCUN1D4 (see all 100):
		hsa-miR-300 hsa-miR-15a hsa-miR-128 hsa-miR-4274 hsa-miR-200b hsa-miR-3148 hsa-miR-130b hsa-miR-374b*

		SwitchGear 3'UTR luciferase reporter plasmid: DCUN1D4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCUN1D4 (see all 6) OriGene shRNA RFP: DCUN1D4 OriGene siRNA: DCUN1D4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCUN1D4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): DCUN1D4 (NM_015115)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCUN1D4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCUN1D4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCUN1D4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DCUN1D4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCUN1D4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCUN1D4

Additional cDNA sequence:

AK027051.1 AK124346.1 AK294894.1 AK294896.1 BC015240.1 BC041702.1 BC053897.1 BX537944.1

BX640660.1 D87466.1

16 DOTS entries:

DT.100726691 DT.445259 DT.91658198 DT.86854420 DT.101984033 DT.95317671 DT.216963 DT.91917580

DT.92011120 DT.97789117 DT.100709206 DT.100721365 DT.100821535 DT.121232849 DT.121232856 DT.97765242

24/209 AceView cDNA sequences (see all 209):

BQ948950 AL700442 BX477958 AI625850 BQ675161 BU630784 BC053897 AW151544

CD300375 BC041702 AI087327 Z41823 BQ722438 AI434436 AW263041 AA719762

BM699002 CF264924 AU117686 CD677232 AA213653 CB118671 AA854727 BX642413

GeneLoc Exon Structure

5/17 Alternative Splicing Database (ASD) splice patterns (SP) for DCUN1D4 (see all 17) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	·	8c	·	8d	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	·	12c	^	13a	·	13b	^	14	^	15	^	16	^	17a	·
SP1:															-		-								-				-		-		-												-		-		-		-
SP2:															-		-								-				-		-		-												-		-		-		-
SP3:																													-		-		-												-				-		-
SP4:															-		-								-				-
SP5:																																													-		-		-		-

ExUns:	17b	·	17c	^	18	^	19a	·	19b	·	19c	·	19d	·	19e	^	20
SP1:
SP2:	-		-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for DCUN1D4

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DCUN1D4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATAAAAAGT

About this image

DCUN1D4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Retina

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DCUN1D4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DCUN1D4

SOURCE GeneReport for Unigene cluster: Hs.605388

SABiosciences Custom PCR Arrays for DCUN1D4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCUN1D4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DCUN1D4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCUN1D4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCUN1D4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCUN1D4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for DCUN1D4 gene from 7/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dcun1d4^{1 , 5}	DCN1, defective in cullin neddylation 1, domain containing more^{1, 5}	92.01(n)¹ 96.58(a)¹		5 (38.85 cM)⁵ 100737¹ NM_178896.5¹ NP_849227.1¹ 73481002⁵
chicken (Gallus gallus)	Aves	DCUN1D4¹	DCN1, defective in cullin neddylation 1, domain containing more	87.67(n) 94.18(a)		422762 XM_420715.2 XP_420715.2
lizard (Anolis carolinensis)	Reptilia	DCUN1D4⁶	--	89(a)	1 ↔ 1	GL343293.1(1182185-1198383)
zebrafish (Danio rerio)	Actinopterygii	Dr.16505²	Transcribed sequence with moderate similarity to protein more	78.19(n)		CF550505.1
fruit fly (Drosophila melanogaster)	Insecta	CG6597¹	CG6597	59.11(n) 64(a)		40231 NM_001202210.2 NP_001189139.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G15860⁶	uncharacterized protein	31(a)	1 → many	1(5454785-5457022)
rice (Oryza sativa)	Liliopsida	--	DCN1, putative, expressed	30(a)	1 → many	8(21352670-21358025)

ENSEMBL Gene Tree for DCUN1D4 (if available)
TreeFam Gene Tree for DCUN1D4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DCUN1D4 gene

DCUN1D5² DCUN1D1² DCUN1D3² DCUN1D2²

5 SIMAP similar genes for DCUN1D4 using alignment to 12 protein entries: DCNL4_HUMAN (see all proteins):

RBMS2 DCUN1D5 DCUN1D2 DCUN1D1 SNRPF

DCUN1D4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for DCUN1D4
1 CNV: 3494

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCUN1D4

DNA2.0 Custom Variant and Variant Library Synthesis for DCUN1D4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DCUN1D4 for disorders           About GeneDecksing

OMIM gene information: 612977    OMIM disorders: --

2 diseases for DCUN1D4:    About MalaCards

pancreatic cancer pancreatitis

Export disorders for DCUN1D4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DCUN1D4 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with DCUN1D4)

Utopia: connect your pdf to the dynamic
world of online information

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. (PubMed id 15988528)^{1, 3} Kurz T....Peter M. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. (PubMed id 21940857)¹ Scott D.C.... Schulman B.A. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PubMed id 18654987)¹ Thalappilly S....Dusetti N.J. (2008)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The LIFEdb database in 2006. (PubMed id 16381901)¹ Mehrle A....Wiemann S. (2006)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23142	HGNC: 28998	AceView: KIAA0276	Ensembl:ENSG00000109184	euGenes: HUgn23142
ECgene: DCUN1D4	H-InvDB: DCUN1D4

(According to HUGE)
About This Section

HUGE: KIAA0276

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DCUN1D4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DCUN1D4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DCUN1D4 gene:
Search GeneIP for patents involving DCUN1D4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for DCUN1D4
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCUN1D4		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCUN1D4
	OriGene Protein Over-expression Lysate for DCUN1D4		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for DCUN1D4		OriGene 3'-UTR Clone for DCUN1D4
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCUN1D4
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for DCUN1D4		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for DCUN1D4		OriGene Custom Protein Services for DCUN1D4
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DCUN1D4
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCUN1D4
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCUN1D4
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCUN1D4
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCUN1D4
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCUN1D4

	GenScript Custom Purified and Recombinant Proteins Services for DCUN1D4		GenScript cDNA clones with any tag delivered in your preferred vector for DCUN1D4
	GenScript Custom Assay Services for DCUN1D4		GenScript Custom Superior Antibodies Services for DCUN1D4
	GenScript Custom overexpressing Cell Line Services for DCUN1D4		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in DCUN1D4 promoter
	Search Chromatin IP Primers for DCUN1D4
	RT² qPCR Primer Assay in human, mouse, rat DCUN1D4
	Search GNC Networks for DCUN1D4
	SABiosciences Custom PCR Arrays for DCUN1D4

Search Tocris compounds for DCUN1D4

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	DCUN1D4 antibodies
	DCUN1D4 proteins
	DCUN1D4 lysates

	Search for Antibodies for DCUN1D4 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for DCUN1D4
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

DCUN1D4 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for DCUN1D4

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCUN1D4

	SwitchGear 3'UTR luciferase reporter plasmids for DCUN1D4
	SwitchGear Promoter luciferase reporter plasmids for DCUN1D4

Search ThermoFisher Antibodies for DCUN1D4

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCUN1D4

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes DCUN1D4 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

DCUN1D4 Gene

DCN1, defective in cullin neddylation 1, domain containing...

Aliases
for DCUN1D4 gene

Summaries
for DCUN1D4 gene

Genomic Views
for DCUN1D4 gene

Proteins
for DCUN1D4 gene

Protein Domains /
Families
for DCUN1D4 gene

Function
for DCUN1D4 gene

Pathways & Interactions
for DCUN1D4 gene

Drugs & Compounds
for DCUN1D4 gene

Transcripts
for DCUN1D4 gene

Expression
for DCUN1D4 gene

Orthologs
for DCUN1D4 gene

Paralogs
for DCUN1D4 gene

Genomic Variants
for DCUN1D4 gene

Disorders / Diseases
for DCUN1D4 gene

Publications
for DCUN1D4 gene

External Searches for DCUN1D4 gene

Genome Databases showing DCUN1D4 gene

Other Databases showing DCUN1D4 gene

Specialized Databases showing DCUN1D4 gene

Intellectual Property
for DCUN1D4 gene

Products
for DCUN1D4 gene

View Random Gene

Advanced Search

Export list of displayed genes

DCUN1D4 Gene

DCN1, defective in cullin neddylation 1, domain containing...

Aliasesfor DCUN1D4 gene

Summariesfor DCUN1D4 gene

Genomic Viewsfor DCUN1D4 gene

Proteinsfor DCUN1D4 gene

Protein Domains /Familiesfor DCUN1D4 gene

Functionfor DCUN1D4 gene

Pathways & Interactionsfor DCUN1D4 gene

Drugs & Compoundsfor DCUN1D4 gene

Transcriptsfor DCUN1D4 gene

Expression for DCUN1D4 gene

Orthologsfor DCUN1D4 gene

Paralogsfor DCUN1D4 gene

Genomic Variantsfor DCUN1D4 gene

Disorders / Diseasesfor DCUN1D4 gene

Publicationsfor DCUN1D4 gene

External Searches for DCUN1D4 gene

Genome Databases showing DCUN1D4 gene

Other Databases showing DCUN1D4 gene

Specialized Databases showing DCUN1D4 gene

Intellectual Propertyfor DCUN1D4 gene

Productsfor DCUN1D4 gene

View Random Gene

Aliases
for DCUN1D4 gene

Summaries
for DCUN1D4 gene

Genomic Views
for DCUN1D4 gene

Proteins
for DCUN1D4 gene

Protein Domains /
Families
for DCUN1D4 gene

Function
for DCUN1D4 gene

Pathways & Interactions
for DCUN1D4 gene

Drugs & Compounds
for DCUN1D4 gene

Transcripts
for DCUN1D4 gene

Expression
for DCUN1D4 gene

Orthologs
for DCUN1D4 gene

Paralogs
for DCUN1D4 gene

Genomic Variants
for DCUN1D4 gene

Disorders / Diseases
for DCUN1D4 gene

Publications
for DCUN1D4 gene

Intellectual Property
for DCUN1D4 gene

Products
for DCUN1D4 gene