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DCTN6 Gene

protein-coding   GIFtS: 56
GCID: GC08P030013

Dynactin 6

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dynactin 61 2     Dynactin Subunit 62
WS32 3 5     Novel RGD-Containing Protein2
Dynactin Subunit P272 3     p272
Protein WS-32 3     P275
WS-32     

External Ids:    HGNC: 169641   Entrez Gene: 106712   Ensembl: ENSG000001046717   OMIM: 6129635   UniProtKB: O003993   

Export aliases for DCTN6 gene to outside databases

Previous GC identifers: GC08P029929 GC08P030464 GC08P029870 GC08P030071 GC08P030133 GC08P028558


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DCTN6 Gene:
The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers
adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity
with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological
function of this gene is not known. (provided by RefSeq, Jul 2008)

GeneCards Summary for DCTN6 Gene:
DCTN6 (dynactin 6) is a protein-coding gene. GO annotations related to this gene include dynein binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_167187.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DCTN6 gene promoter:
         c-Fos   AP-1   JunB   Fra-1   FosB   GATA-6   FOXC1   JunD   STAT3   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDCTN6 promoter sequence
   Search Chromatin IP Primers for DCTN6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DCTN6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p12-p11   Ensembl cytogenetic band:  8p12   HGNC cytogenetic band: 8p12-p11

DCTN6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCTN6 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P030013:  view genomic region     (about GC identifiers)

Start:
30,013,813 bp from pter      End:
30,041,156 bp from pter
Size:
27,344 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DCTN6_HUMAN, O00399 (See protein sequence)
Recommended Name: Dynactin subunit 6  
Size: 190 amino acids; 20747 Da
Subunit: Member of the pointed-end complex of the dynactin shoulder complex which contains DCTN4, DCTN5 and DCTN6
subunits and ACTR10. Within the complex DCTN6 forms a heterodimer with DCTN5. Interacts with PLK1
1 PDB 3D structure from and Proteopedia for DCTN6:
3TV0 (3D)    
Secondary accessions: B2RAC1

Explore the universe of human proteins at neXtProt for DCTN6: NX_O00399

Explore proteomics data for DCTN6 at MOPED

Post-translational modifications: 

  • Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates
    its recruitment to kinetochores1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DCTN6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006562.1  
    ENSEMBL proteins: 
     ENSP00000221114   ENSP00000430109   ENSP00000431017   ENSP00000427955   ENSP00000429408  
    Reactome Protein details: O00399

    DCTN6 Human Recombinant Protein Products:

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    antibodies-online peptides for DCTN6

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001451 Hexapep_transf
     IPR027777 DCTN6
     IPR011004 Trimer_LpxA-like

    Graphical View of Domain Structure for InterPro Entry O00399

    ProtoNet protein and cluster: O00399

    UniProtKB/Swiss-Prot: DCTN6_HUMAN, O00399
    Similarity: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily


    Find genes that share domains with DCTN6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045502dynein binding IEA--
         
    Find genes that share ontologies with DCTN6           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for DCTN6:
     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DCTN6

    miRNA
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    miRTarBase miRNAs that target DCTN6:
    hsa-mir-93-5p (MIRT027961)

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    5 qRT-PCR Assays for microRNAs that regulate DCTN6:
    hsa-miR-361-5p hsa-miR-3146 hsa-miR-590-3p hsa-miR-410 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidDCTN6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DCTN6

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DCTN6_HUMAN, O00399: Cytoplasm, cytoskeleton (By similarity). Chromosome, centromere, kinetochore
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol4
    nucleus3
    plasma membrane3
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005813centrosome IDA--
    GO:0005829cytosol TAS--
    GO:0005869dynactin complex IEA--

    Find genes that share ontologies with DCTN6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DCTN6 About    
    See pathways by source

    SuperPathContained pathways About
    1Cytoplasmic microtubules
    Cytoplasmic microtubules0.32
    Cytoskeleton remodeling Neurofilaments0.32
    2Class I MHC mediated antigen processing and presentation
    Adaptive Immune System0.41
    3Vasopressin-regulated water reabsorption
    Vasopressin-regulated water reabsorption
    4MHC class II antigen presentation
    MHC class II antigen presentation
    5Cell cycle Spindle assembly and chromosome separation
    Cell cycle Spindle assembly and chromosome separation


    Find genes that share SuperPaths with DCTN6           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for DCTN6
        Cell cycle Spindle assembly and chromosome separation
    Cytoskeleton remodeling Neurofilaments


    1 Reactome Pathway for DCTN6
        MHC class II antigen presentation


    1 Kegg Pathway  (Kegg details for DCTN6):
        Vasopressin-regulated water reabsorption

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DCTN6
    Interactions:

        Search GeneGlobe Interaction Network for DCTN6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DCTN6 (O003993 ENSP000002211144) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCOA3Q9Y6Q93, ENSP000003610664I2D: score=1 STRING: ENSP00000361066
    DCTN5Q9BTE13, ENSP000003000874I2D: score=1 STRING: ENSP00000300087
    TRIM2Q9C0403I2D: score=1 
    DCTN1ENSP000003547914STRING: ENSP00000354791
    DYNC1H1ENSP000003489654STRING: ENSP00000348965
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    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--

    Find genes that share ontologies with DCTN6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DCTN6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DCTN6 gene: 
    NM_006571.3  

    Unigene Cluster for DCTN6:

    Dynactin 6
    Hs.158427  [show with all ESTs]
    Unigene Representative Sequence: NM_006571
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221114(uc003xhy.3) ENST00000522141 ENST00000522540 ENST00000520829
    ENST00000523666 ENST00000519830
    miRNA
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    Block miRNA regulation of human, mouse, rat DCTN6 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate DCTN6:
    hsa-miR-361-5p hsa-miR-3146 hsa-miR-590-3p hsa-miR-410 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidDCTN6 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat DCTN6
      QuantiFast Probe-based Assays in human, mouse, rat DCTN6

    Additional mRNA sequence: 

    AK314128.1 BC013175.1 CR456851.1 D84145.1 

    7 DOTS entries:

    DT.216538  DT.120629947  DT.120629922  DT.75167111  DT.86852307  DT.120629895  DT.97813580 

    Selected AceView cDNA sequences (see all 163):

    AA962529 CA421380 BC013175 CA419657 AI758996 AI084013 CA942967 CD367288 
    AA682486 BF032846 BM711013 AL537750 BI769548 AA825526 BF725894 CR590871 
    AI423623 CA389528 AI749963 CA314695 CA438919 D79389 CB164258 AA815228 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for DCTN6    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b
    SP1:                                      -                 -               
    SP2:                                      -                                 
    SP3:                          -           -                 -               
    SP4:                          -           -                                 
    SP5:                                                                        


    ECgene alternative splicing isoforms for DCTN6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DCTN6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTTATATT
    DCTN6 Expression
    About this image


    DCTN6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Adrenal Gland (Endocrine System)
    DCTN6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DCTN6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.158427

    UniProtKB/Swiss-Prot: DCTN6_HUMAN, O00399
    Tissue specificity: Ubiquitous

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for DCTN6 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dctn61 , 5 dynactin 61, 5 86.49(n)1
    96.32(a)1
      8 (20.90 cM)5
    224281  NM_011722.31  NP_035852.11 
     340904205 
    chicken
    (Gallus gallus)
    Aves DCTN61 dynactin 6 78.42(n)
    93.16(a)
      771257  NM_001277829.1  NP_001264758.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCTN66
    dynactin 6
    87(a)
    1 ↔ 1
    GL343257.1(752935-764235)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.157362 Transcribed sequence with moderate similarity to protein more 79.03(n)    142031913 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1121021 zgc:112102 70.09(n)
    81.62(a)
      553678  NM_001020651.1  NP_001018487.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)37Ce1 lethal (2) 37Ce 52.83(n)
    48.54(a)
      35195  NM_136105.3  NP_609949.1 
    worm
    (Caenorhabditis elegans)
    Secernentea dnc-61 dnc-6 46.23(n)
    37.5(a)
      171891  NM_058715.6  NP_491116.2 


    ENSEMBL Gene Tree for DCTN6 (if available)
    TreeFam Gene Tree for DCTN6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DCTN6 gene

    Find genes that share paralogs with DCTN6           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for DCTN6
    PGOHUM00000237485


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DCTN6 (see all 581)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1824600761,2
    --30011931(+) CTGAGG/TGTGAT 1 -- us2k10--------
    rs755621691,2
    F--30012042(+) AAGCCC/TATCAT 1 -- us2k11Minor allele frequency- T:0.09WA 118
    rs800217991,2
    C--30012047(+) CATCAC/TCAGTT 1 -- us2k10--------
    rs1882624611,2
    --30012051(+) ATCAGC/TTCACT 1 -- us2k10--------
    rs47334001,2
    C,F,A,H--30012514(+) TTTAAA/GAGGAA 1 -- us2k1 trp324Minor allele frequency- G:0.32NS EA NA WA CSA 2354
    rs2002094521,2
    C--30012653(+) CTCCC-/CATCTC 1 -- us2k10--------
    rs1180019131,2
    F--30012699(+) GCCACG/CCGCCT 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs1389119191,2
    --30012746(+) CAAGAG/TAACTA 1 -- us2k10--------
    rs70074451,2
    C,H--30012783(+) TGAGGG/AGGTGT 1 -- us2k114Minor allele frequency- A:0.01NS EA NA WA CSA 775
    rs1927679951,2
    --30013071(+) GATACC/GACTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DCTN6 (30013813 - 30041156 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DCTN6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6139CNV Loss18451855
    nsv831277CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DCTN6
    DNA2.0 Custom Variant and Variant Library Synthesis for DCTN6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612963    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for DCTN6:
    Newcastle disease

    Find genes that share disorders with DCTN6           About GenesLikeMe

    Genetic Association Database (GAD): DCTN6

    Export disorders for DCTN6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCTN6 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with DCTN6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel gene, WS-3, in human chromosome 8p11-p12. (PubMed id 9168138)1, 2, 3, 9 Ichikawa K.... Furuichi Y. (Gene 1997)
    2. Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit. (PubMed id 23455152)1, 2 Yeh T.Y....Schroer T.A. (EMBO J. 2013)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Dynactins p25 and p27 are predicted to adopt the LbetaH fold. (PubMed id 15043994)1, 9 Parisi G....Echave J. (FEBS Lett. 2004)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    8. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. (PubMed id 21577200)1 Li C....O'Malley B.W. (Oncogene 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10671 HGNC: 16964 AceView: DCTN6 Ensembl:ENSG00000104671 euGenes: HUgn10671
    ECgene: DCTN6 Kegg: 10671 H-InvDB: DCTN6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DCTN6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DCTN6 gene:
    Search GeneIP for patents involving DCTN6

    GeneCards and IP:
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