Aliases for DCT Gene
External Ids for DCT Gene
Previous HGNC Symbols for DCT Gene
Previous GeneCards Identifiers for DCT Gene
GeneCards Summary for DCT Gene
DCT (Dopachrome Tautomerase) is a Protein Coding gene. Diseases associated with DCT include Microphthalmia and Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and Tyrosine metabolism. GO annotations related to this gene include oxidoreductase activity and dopachrome isomerase activity. An important paralog of this gene is TYRP1.
UniProtKB/Swiss-Prot for DCT Gene
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979). Involved in regulating eumelanin and phaeomelanin levels.