Aliases for DCN Gene
External Ids for DCN Gene
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq, Jul 2008]
GeneCards Summary for DCN Gene
DCN (Decorin) is a Protein Coding gene. Diseases associated with DCN include corneal dystrophy, congenital stromal and burn scar. Among its related pathways are Proteoglycans in cancer and Disease. GO annotations related to this gene include protein N-terminus binding and glycosaminoglycan binding. An important paralog of this gene is ECM2.
UniProtKB/Swiss-Prot for DCN Gene
May affect the rate of fibrils formation