DCLRE1B Gene
protein-coding GIFtS: 49
GCID: GC01P114447
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|
DNA cross-link repair 1B(Previous names: DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)...)
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Aliases
for DCLRE1B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| DNA Cross-Link Repair 1B1 2 | | FLJ139981 | | SNM1B1 2 3 5 | | 5' Exonuclease Apollo2 | | DNA Cross-Link Repair 1B (PSO2 Homolog, S. Cerevisiae)1 2 | | PSO2 Homolog2 | | SNMIB2 3 | | EC 3.1.-.-3 | | SNM1 Homolog B2 3 | | DNA Cross-Link Repair 1B Protein3 | | APOLLO2 5 | | HSNM1B1 | | FLJ128101 | | |
Export aliases for DCLRE1B gene to outside databasesPrevious GC identifers: GC01P114861 GC01P113330 GC01P113548 GC01P113746 GC01P114160 GC01P114249 GC01P112306 |
Summaries
for DCLRE1B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DCLRE1B:
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, andsegregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrandcross-links (Dronkert et al., 2000 (PubMed 10848582)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: DCR1B_HUMAN, Q9H816Function: 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase.Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, therebyensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2at the leading end telomeres and by processing leading-end telomeres immediately after their replication via itsexonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-endtelomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNArepair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication bycontrolling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during forkpassage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response toDNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involvedin prophase checkpoint
Gene Wiki entry for DCLRE1B
|
Genomic Views
for DCLRE1B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DCLRE1B gene promoter:
Bach2 Lmo2 Nkx2-5 Max HEN1 PPAR-gamma1 Zic1 HFH-1 PPAR-gamma2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for DCLRE1B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCLRE1B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13.2 Ensembl cytogenetic band: 1p13.2 HGNC cytogenetic band: 1p11.1DCLRE1B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P114447: view genomic region
(about GC identifiers)
Start:
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114,447,763 bp from pter |
End:
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114,456,708 bp from pter |
Size:
|
8,946 bases |
Orientation:
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plus strand |
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Proteins
for DCLRE1B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DCR1B_HUMAN, Q9H816 (See
protein sequence)Recommended Name: 5' exonuclease Apollo Size: 532 amino acids; 60002 Da
Subunit: Interacts with TERF2; the interaction is direct. Interacts with MUS81, MRE11 and FANCD2. Interacts with HSPA2,HSPA8 and HSPA14. Interacts with SPAG5
Subcellular location: Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Mainly localizes totelomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome
Miscellaneous: Was named 'Apollo' in reference to the twin brother of 'Artemis' in Greek mythology (PubMed:16730175 andPubMed:16730176). Artemis/DCLRE1C is a related nuclease
Sequence caution: Sequence=BAB14284.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for DCLRE1B:3BUA (3D)
3ZDK (3D)
Secondary accessions: Q9H9E5Explore the universe of human proteins at neXtProt for DCLRE1B: NX_Q9H816
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR1
Ubiquitinated, leading to its degradation. Interaction with TERF2 protects it from ubiquitination1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H816
DCLRE1B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_073747.1
ENSEMBL proteins: ENSP00000358576
Human Recombinant Protein Products for DCLRE1B:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DCLRE1B for ontologies About GeneDecksing
DCLRE1B Antibody Products:
Assay Products for DCLRE1B: |
Protein
Domains /
Families
for DCLRE1B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DCLRE1B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H816ProtoNet protein and cluster: Q9H816 UniProtKB/Swiss-Prot: DCR1B_HUMAN, Q9H816Domain: The TBM domain mediates interaction with TERF2Similarity: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family |
Function
for DCLRE1B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DCR1B_HUMAN, Q9H816Function: 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase.Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, therebyensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2at the leading end telomeres and by processing leading-end telomeres immediately after their replication via itsexonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-endtelomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNArepair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication bycontrolling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during forkpassage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response toDNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involvedin prophase checkpoint Enzyme Number (IUBMB): EC 3.1.-.-1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
DCLRE1B for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for DCLRE1B:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Dclre1b):
DCLRE1B for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Dclre1btm1Schg for DCLRE1B
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCLRE1B (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCLRE1B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCLRE1B |
|
Pathways & Interactions
for DCLRE1B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DCLRE1B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/8 Interacting proteins for DCLRE1B (Q9H8161, 2, 3 ENSP000003585764) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
DCLRE1B for ontologies About GeneDecksing
|
Drugs & Compounds
for DCLRE1B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DCLRE1B
Search CenterWatch for drugs/clinical trials and news about DCLRE1B / DCR1B
|
Transcripts
for DCLRE1B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DCLRE1B gene: NM_022836.3 Unigene Cluster for DCLRE1B: DNA cross-link repair 1B Hs.591412 [show with all ESTs]Unigene Representative Sequence: NM_0228362 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369563(uc001eeh.3 uc001eeg.3 uc001eei.3) ENST00000466480
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCLRE1B (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCLRE1B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DCLRE1B (NM_022836) | | | DNA2.0 Custom Codon Optimized Gene
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Additional cDNA sequence: AF306690.1 AF306691.1 AF306692.1 AF306693.1 AK022872.1 AK024060.1 BC011950.1 BC029687.1 CR936679.1 4 DOTS entries: DT.302629 DT.100706381 DT.100813096 DT.121428338 24/71 AceView cDNA sequences (see all 71): AF306691 BM699019 BM457117 BP339369 BU628478 AK024060 BU616748 AI270720 CR591475 AF306692 BU620261 NM_022836 AK022872 AA676673 CA423843 BC029687 AA424275 AI805858 BE386107 AI272667 BX410150 BX410149 BX327525 AU127973
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for DCLRE1B About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for DCLRE1B
|
Expression
for DCLRE1B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DCLRE1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAGTATACC
About this image
See DCLRE1B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DCLRE1B
SOURCE GeneReport for Unigene cluster: Hs.591412
SABiosciences Expression via Pathway-Focused PCR Arrays including DCLRE1B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCLRE1B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DCLRE1B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCLRE1B | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCLRE1B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCLRE1B |
Orthologs
for DCLRE1B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for DCLRE1B gene from 5/16 species (see all 16) About this table
ENSEMBL Gene Tree for DCLRE1B (if available)
TreeFam Gene Tree for DCLRE1B (if available) |
Paralogs
for DCLRE1B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for DCLRE1B gene
- DCLRE1C2 DCLRE1A2
DCLRE1B for paralogs About GeneDecksing
|
Genomic Variants
for DCLRE1B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DCLRE1B (114447763 - 114456708 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for DCLRE1B
3 CNVs: 2322 3306 64644 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCLRE1B |
|
Disorders
/ Diseases
for DCLRE1B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DCLRE1B for disorders About GeneDecksing
OMIM gene information: 609683
OMIM disorders: --
UniProtKB/Swiss-Prot: DCR1B_HUMAN, Q9H816
Defects in DCLRE1B may be a cause of Hoyeraal-Hreidarsson syndrome (HHS) [MIM:300240]. HHS is a multisystemdisorder affecting males and is characterized by aplastic anemia, immunodeficiency, microcephaly, cerebellarhypoplasia, and growth retardation. Note=An aberrant splice variant designated Apollo-Delta has been found in apatient with Hoyeraal-Hreidarsson syndrome. Apollo-Delta hampers the proper replication of telomeres, leading to majortelomeric dysfunction and cellular senescence, but maintains its DNA interstrand cross-link repair function in thewhole genome
8  diseases for DCLRE1B: About MalaCardshoyeraal-hreidarsson syndrome cerebellar hypoplasia aplastic anemia fanconi's anemia
anemia microcephaly twinning malaria
Export disorders for DCLRE1B gene to outside databases
|
Publications
for DCLRE1B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DCLRE1B gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with DCLRE1B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- TRF2 and apollo cooperate with topoisomerase 2alpha t o protect human telomeres from replicative damage. (PubMed id 20655466)1, 2 Ye J....Gilson E. (2010)
- Evidence for hSNM1B/Apollo functioning in the HSP70 mediated DNA damage response. (PubMed id 19411856)1, 2 Anders M....Demuth I. (2009)
- SNM1B/Apollo interacts with astrin and is required for the prophase cell cycle checkpoint. (PubMed id 19197158)1, 2 Liu L....Legerski R. (2009)
- Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. (PubMed id 18469862)1, 2 Bae J.B....Legerski R.J. (2008)
- The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2. (PubMed id 18593705)1, 2 Freibaum B.D. and Counter C.M. (2008)
- Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation. (PubMed id 18468965)1, 2 Demuth I....Concannon P. (2008)
- Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase. (PubMed id 16730176)1, 2 van Overbeek M. and de Lange T. (2006)
- The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair. (PubMed id 16730175)1, 2 Lenain C....Gilson E. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- hSnm1B is a novel telomere-associated protein. (PubMed id 16606622)1, 2 Freibaum B.D. and Counter C.M. (2006)
|
External Searches for DCLRE1B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DCLRE1B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DCLRE1B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DCLRE1B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for DCLRE1B gene:
Search GeneIP for patents involving DCLRE1B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DCLRE1B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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