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DCLRE1A Gene

protein-coding   GIFtS: 61
GCID: GC10M115584

DNA Cross-Link Repair 1A

(Previous names: DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DNA Cross-Link Repair 1A1 2     PSO2 Homolog (S. Cerevisiae)1
SNM12 3 5     PSO22
SNM1A2 3 5     DNA Cross-Link Repair 1A Protein2
SNM1 Homolog A2 3     DNA-Crosslink Repair Gene SNM12
KIAA00863 5     hSNM13
DNA Cross-Link Repair 1A (PSO2 Homolog, S. Cerevisiae)1     hSNM1A3

External Ids:    HGNC: 176601   Entrez Gene: 99372   Ensembl: ENSG000001989247   OMIM: 6096825   UniProtKB: Q6PJP83   

Export aliases for DCLRE1A gene to outside databases

Previous GC identifers: GC10M114501 GC10M114828 GC10M115725 GC10M115259 GC10M109221


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DCLRE1A Gene:
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA
cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the
mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. (provided by RefSeq,
Nov 2012)

GeneCards Summary for DCLRE1A Gene:
DCLRE1A (DNA cross-link repair 1A) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is DCLRE1B.

UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
arrest in early prophase in response to mitotic spindle poisons

Gene Wiki entry for DCLRE1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DCLRE1A gene promoter:
         E2F-4   E2F-3a   AML1a   p53   E2F-2   CREB   E2F   E2F-1   HSF2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DCLRE1A promoter sequence
   Search Chromatin IP Primers for DCLRE1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DCLRE1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.1   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q25.1

DCLRE1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCLRE1A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M115584:  view genomic region     (about GC identifiers)

Start:
115,594,484 bp from pter      End:
115,614,142 bp from pter
Size:
19,659 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8 (See protein sequence)
Recommended Name: DNA cross-link repair 1A protein  
Size: 1040 amino acids; 116400 Da
Subunit: Binds constitutively to TP53BP1. Binds CDC27, which is itself a component of the anaphase promoting
complex (APC). Binds PIAS1
Sequence caution: Sequence=BAA07646.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for DCLRE1A:
4B87 (3D)    
Secondary accessions: D3DRC1 Q14701 Q6P5Y3 Q6PKL4

Explore the universe of human proteins at neXtProt for DCLRE1A: NX_Q6PJP8

Explore proteomics data for DCLRE1A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DCLRE1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001258745.1  NP_055696.3  

    ENSEMBL proteins: 
     ENSP00000355185   ENSP00000358311  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR011084 DRMBL
     IPR001279 Beta-lactamas-like

    Graphical View of Domain Structure for InterPro Entry Q6PJP8

    ProtoNet protein and cluster: Q6PJP8

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Similarity: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family


    Find genes that share domains with DCLRE1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCR1A_HUMAN, Q6PJP8
    Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
    arrest in early prophase in response to mitotic spindle poisons
    Induction: During mitosis. The mRNA encoding this protein contains an internal ribosome entry site (IRES) in its
    5'-UTR. This 5'-UTR generally suppresses translation while specifically promoting expression during mitosis, when
    cap-dependent translation may be impaired

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
         
    Find genes that share ontologies with DCLRE1A           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for DCLRE1A:
     Increased circadian period len  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Dclre1a):
     cellular  homeostasis/metabolism  immune system  mortality/aging  tumorigenesis 

    Find genes that share phenotypes with DCLRE1A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for DCLRE1A: Dclre1atm1Remo Dclre1atm1Rleg Dclre1atm1Roka

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    miRTarBase miRNAs that target DCLRE1A:
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    SwitchGear 3'UTR luciferase reporter plasmidDCLRE1A 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DCR1A_HUMAN, Q6PJP8: Nucleus. Note=In some cells it may be found in typically 1 or 2 discrete nuclear aggregates
    of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in
    number following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with
    those formed by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005730nucleolus ----

    Find genes that share ontologies with DCLRE1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DCLRE1A About    
    See pathways by source

    SuperPathContained pathways About
    1Chks in Checkpoint Regulation
    DNA Repair Mechanisms0.32

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for DCLRE1A
        DNA Repair Mechanisms


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DCLRE1A
    Interactions:

        GeneGlobe Interaction Network for DCLRE1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DCLRE1A (Q6PJP83 ENSP000003551854) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIAS1O759253, ENSP000002496364I2D: score=2 STRING: ENSP00000249636
    ATMQ133153, ENSP000002786164I2D: score=1 STRING: ENSP00000278616
    TP53BP1Q128883, ENSP000003714754I2D: score=1 STRING: ENSP00000371475
    UBCENSP000003448184STRING: ENSP00000344818
    PCNAENSP000003684384STRING: ENSP00000368438
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006289nucleotide-excision repair IEA--
    GO:0007067mitosis IEA--

    Find genes that share ontologies with DCLRE1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DCLRE1A (DCR1A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DCLRE1A gene (2 alternative transcripts): 
    NM_001271816.1  NM_014881.4  

    Unigene Cluster for DCLRE1A:

    DNA cross-link repair 1A
    Hs.1560  [show with all ESTs]
    Unigene Representative Sequence: NM_014881
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361384(uc001law.2) ENST00000369305 ENST00000476112
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidDCLRE1A 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK307187.1 BC013124.2 BC062582.1 D42045.1 

    3 DOTS entries:

    DT.213619  DT.100020107  DT.301063 

    Selected AceView cDNA sequences (see all 83):

    NM_014881 D42045 BU623158 N46162 AA860577 AI682192 CB130234 BC013124 
    AI681848 BM703845 BM698798 AA630074 AL360205 CB146751 AL043226 BC062582 
    BX475117 BX433249 AL599941 AI016253 AI243372 AI679517 N84962 BG617256 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for DCLRE1A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                              
    SP2:        -                                                                     


    ECgene alternative splicing isoforms for DCLRE1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DCLRE1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCAGTTATA
    DCLRE1A Expression
    About this image


    DCLRE1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
    DCLRE1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DCLRE1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.1560

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Tissue specificity: Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCLRE1A gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dclre1a1 , 5 DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)1, 5 73.16(n)1
    65.9(a)1
      19 (51.89 cM)5
    559471  NM_018831.41  NP_061301.31 
     565291675 
    chicken
    (Gallus gallus)
    Aves DCLRE1A1 DNA cross-link repair 1A 60.06(n)
    51.57(a)
      423902  NM_001008683.1  NP_001008683.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCLRE1A6
    DNA cross-link repair 1A
    38(a)
    1 ↔ 1
    GL343204.1(525082-545960)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.256382 Xenopus laevis transcribed sequence with weak similarity more 73.73(n)    BU913862.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc49f052 Transcribed sequence with weak similarity to protein more 80.28(n)    BM777630.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PSO2(YMR137C)4 Nuclease required for a post-incision step in the repair more   --   13(544963-542978) 855168  NP_013857.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SNM11 SNM1 52.55(n)
    48.47(a)
      822280  NM_001035696.1  NP_001030773.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g04018001 Os04g0401800 48.48(n)
    44.09(a)
      4335730  NM_001059225.1  NP_001052690.1 


    ENSEMBL Gene Tree for DCLRE1A (if available)
    TreeFam Gene Tree for DCLRE1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DCLRE1A gene
    DCLRE1B2  DCLRE1C2  

    Find genes that share paralogs with DCLRE1A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DCLRE1A (see all 460)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs172289321,2
    C,F--115593993(-) GTGACAA/-GAGAT 2 -- ds50011Minor allele frequency- -:0.01NS 168
    rs1893674141,2
    --115594092(+) TCTACC/TCAACT 2 -- ds50010--------
    rs1813071281,2
    --115594141(+) TGGGCC/TGGGTG 2 -- ds50010--------
    rs172289181,2
    C,F,H--115594147(-) CCACCG/ACACCC 2 -- ds50014Minor allele frequency- A:0.14NS NA 456
    rs172353391,2
    C,F--115594229(-) TGTTGG/ACCAGG 2 -- ds50011Minor allele frequency- A:0.02NS 176
    rs1418962371,2
    --115594362(+) GGAGGC/TTGCAG 2 -- ds50010--------
    rs1472698411,2
    --115594384(+) ACTACA/GGCCCA 2 -- ds50010--------
    rs1849241391,2
    --115594516(+) ATACAC/TGTCAT 2 -- ut310--------
    rs172353321,2
    C--115594577(-) TTTGAA/GGCATT 2 -- ut31 ese31Minor allele frequency- G:0.01NS 174
    rs172353251,2
    C,F--115594589(-) TTAATA/GAAGTA 2 -- ut311Minor allele frequency- G:0.01NS 172

    HapMap Linkage Disequilibrium report for DCLRE1A (115594484 - 115614142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DCLRE1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv507578CNV Insertion20534489
    nsv896016CNV Loss21882294
    nsv831995CNV Gain+Loss17160897
    nsv7211OTHER Inversion18451855

    Human Gene Mutation Database (HGMD): DCLRE1A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DCLRE1A
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609682    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for DCLRE1A:
    Fanconi's anemia

    Find genes that share disorders with DCLRE1A           About GenesLikeMe

    Genetic Association Database (GAD): DCLRE1A
    Human Genome Epidemiology (HuGE) Navigator: DCLRE1A (2 documents)

    Export disorders for DCLRE1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCLRE1A gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with DCLRE1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. (PubMed id 10848582)1, 2, 9 Dronkert M.L.G.... Kanaar R. (Mol. Cell. Biol. 2000)
    2. Genomic organization of a potential human DNA-crosslink repair gene, KIAA0086. (PubMed id 9806498)1, 3, 9 Demuth I. and Digweed M. (Mutat. Res. 1998)
    3. The hSNM1 protein is a DNA 5'-exonuclease. (PubMed id 17804464)1, 3, 9 Hejna J....Moses R. (Nucleic Acids Res. 2007)
    4. hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. (PubMed id 12446782)1, 2, 9 Richie C.T....Legerski R.J. (Mol. Cell. Biol. 2002)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    6. DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation. (PubMed id 15572677)1, 2 Ishiai M....Takata M. (Mol. Cell. Biol. 2004)
    7. Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. (PubMed id 15542852)1, 2 Akhter S.... Legerski R.J. (Mol. Cell. Biol. 2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    10. Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. (PubMed id 12509242)1, 2 Zhang X.... Legerski R.J. (DNA Repair 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9937 HGNC: 17660 AceView: DCLRE1A Ensembl:ENSG00000198924 euGenes: HUgn9937
    ECgene: DCLRE1A H-InvDB: DCLRE1A

    (According to HUGE)
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    HUGE: KIAA0086

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DCLRE1A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DCLRE1A Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/dclre1a/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DCLRE1A gene:
    Search GeneIP for patents involving DCLRE1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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