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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DCLRE1A Gene

protein-coding   GIFtS: 60
GCID: GC10M115584

DNA Cross-Link Repair 1A

(Previous names: DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae))
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
DNA Cross-Link Repair 1A1 2     PSO2 Homolog (S. Cerevisiae)1
SNM12 3 5     PSO22
SNM1A2 3 5     DNA Cross-Link Repair 1A Protein2
SNM1 Homolog A2 3     DNA-Crosslink Repair Gene SNM12
KIAA00863 5     hSNM13
DNA Cross-Link Repair 1A (PSO2 Homolog, S. Cerevisiae)1     hSNM1A3

External Ids:    HGNC: 176601   Entrez Gene: 99372   Ensembl: ENSG000001989247   OMIM: 6096825   UniProtKB: Q6PJP83   

Export aliases for DCLRE1A gene to outside databases

Previous GC identifers: GC10M114501 GC10M114828 GC10M115725 GC10M115259 GC10M109221


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DCLRE1A Gene:
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA
cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the
mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. (provided by RefSeq,
Nov 2012)

GeneCards Summary for DCLRE1A Gene: 
DCLRE1A (DNA cross-link repair 1A) is a protein-coding gene. Diseases associated with DCLRE1A include fanconi's anemia, and alzheimer's disease, and among its related super-pathways are Chks in Checkpoint Regulation. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is DCLRE1B.

UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
arrest in early prophase in response to mitotic spindle poisons

Gene Wiki entry for DCLRE1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DCLRE1A gene promoter:
         E2F-4   E2F-3a   AML1a   p53   E2F-2   CREB   E2F   E2F-1   HSF2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DCLRE1A promoter sequence
   Search SABiosciences Chromatin IP Primers for DCLRE1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCLRE1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.1   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q25.1

DCLRE1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCLRE1A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M115584:  view genomic region     (about GC identifiers)

Start:
115,594,484 bp from pter      End:
115,614,142 bp from pter
Size:
19,659 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8 (See protein sequence)
Recommended Name: DNA cross-link repair 1A protein  
Size: 1040 amino acids; 116400 Da
Subunit: Binds constitutively to TP53BP1. Binds CDC27, which is itself a component of the anaphase promoting
complex (APC). Binds PIAS1
Subcellular location: Nucleus. Note=In some cells it may be found in typically 1 or 2 discrete nuclear aggregates
of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in
number following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with
those formed by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1
Sequence caution: Sequence=BAA07646.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for DCLRE1A:
4B87 (3D)    
Secondary accessions: D3DRC1 Q14701 Q6P5Y3 Q6PKL4

Explore the universe of human proteins at neXtProt for DCLRE1A: NX_Q6PJP8

Explore proteomics data for DCLRE1A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6PJP8

  • DCLRE1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DCLRE1A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001258745.1  NP_055696.3  

    ENSEMBL proteins: 
     ENSP00000355185   ENSP00000358311  

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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    DCLRE1A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR011084 DRMBL
     IPR001279 Beta-lactamas-like

    Graphical View of Domain Structure for InterPro Entry Q6PJP8

    ProtoNet protein and cluster: Q6PJP8

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Similarity: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family


    DCLRE1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCR1A_HUMAN, Q6PJP8
    Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
    arrest in early prophase in response to mitotic spindle poisons
    Induction: During mitosis. The mRNA encoding this protein contains an internal ribosome entry site (IRES) in its
    5'-UTR. This 5'-UTR generally suppresses translation while specifically promoting expression during mitosis, when
    cap-dependent translation may be impaired

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
         
    DCLRE1A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DCLRE1A:
     Increased circadian period len  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Dclre1a):
     cellular  homeostasis/metabolism  immune system  mortality/aging  tumorigenesis 

    DCLRE1A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for DCLRE1A: Dclre1atm1Remo Dclre1atm1Rleg Dclre1atm1Roka

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    SwitchGear 3'UTR luciferase reporter plasmidDCLRE1A 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DCLRE1A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Chks in Checkpoint Regulation
    DNA Repair Mechanisms0.32

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for DCLRE1A
        DNA Repair Mechanisms


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DCLRE1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for DCLRE1A (Q6PJP83 ENSP000003551854) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIAS1O759253, ENSP000002496364I2D: score=2 STRING: ENSP00000249636
    ATMQ133153, ENSP000002786164I2D: score=1 STRING: ENSP00000278616
    TP53BP1Q128883, ENSP000003714754I2D: score=1 STRING: ENSP00000371475
    UBCENSP000003448184STRING: ENSP00000344818
    PCNAENSP000003684384STRING: ENSP00000368438
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006289nucleotide-excision repair IEA--
    GO:0007067mitosis IEA--
    GO:0051301cell division IEA--

    DCLRE1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DCLRE1A (DCR1A)

    Search CenterWatch for drugs/clinical trials and news about DCLRE1A / DCR1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DCLRE1A gene (2 alternative transcripts): 
    NM_001271816.1  NM_014881.4  

    Unigene Cluster for DCLRE1A:

    DNA cross-link repair 1A
    Hs.1560  [show with all ESTs]
    Unigene Representative Sequence: NM_014881
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361384(uc001law.2) ENST00000369305 ENST00000476112

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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate DCLRE1A:
    hsa-miR-3163 hsa-miR-133a hsa-miR-155 hsa-miR-590-3p hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidDCLRE1A 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK307187.1 BC013124.2 BC062582.1 D42045.1 

    3 DOTS entries:

    DT.213619  DT.100020107  DT.301063 

    24/83 AceView cDNA sequences (see all 83):

    NM_014881 AI682192 AI681848 AL043226 AA860577 D42045 BU623158 BC013124 
    AL360205 BC062582 N46162 BM703845 BM698798 CB130234 CB146751 AA630074 
    CA489699 BI091198 BF446475 W03887 BX375172 AW104372 BF035397 AL599941 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for DCLRE1A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                              
    SP2:        -                                                                     


    ECgene alternative splicing isoforms for DCLRE1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DCLRE1A expression in normal human tissues (normalized intensities)      DCLRE1A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCAGTTATA
    DCLRE1A Expression
    About this image


    DCLRE1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             oocyte   
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     
     Blood (Hematopoietic System)

    See DCLRE1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DCLRE1A

    SOURCE GeneReport for Unigene cluster: Hs.1560

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Tissue specificity: Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCLRE1A gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dclre1a1 , 5 DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)1, 5 73.29(n)1
    65.9(a)1
      19 (51.89 cM)5
    559471  NM_018831.41  NP_061301.31 
     565291675 
    chicken
    (Gallus gallus)
    Aves DCLRE1A1 DNA cross-link repair 1A 59.66(n)
    51.03(a)
      423902  NM_001008683.1  NP_001008683.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCLRE1A6
    Uncharacterized protein
    40(a)
    1 ↔ 1
    GL343204.1(525082-545960)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.256382 Xenopus laevis transcribed sequence with weak similarity more 73.73(n)    BU913862.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc49f052 Transcribed sequence with weak similarity to protein more 80.28(n)    BM777630.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Snm13 DNA repair 37(a)   83B1   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PSO2(YMR137C)4 Nuclease required for a post-incision step in the repair more   --   13(544963-542978) 855168  NP_013857.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SNM11 DNA cross-link repair protein SNM1 51.87(n)
    47.26(a)
      822280  NM_113579.2  NP_189302.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g04018001 hypothetical protein 48.41(n)
    44.09(a)
      4335730  NM_001059225.1  NP_001052690.1 


    ENSEMBL Gene Tree for DCLRE1A (if available)
    TreeFam Gene Tree for DCLRE1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DCLRE1A gene
    DCLRE1B2  DCLRE1C2  

    DCLRE1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/460 SNPs in DCLRE1A are shown (see all 460)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0232874
    ----see VAR_0232872 E D mis40--------
    VAR_0232864
    ----see VAR_0232862 K E mis40--------
    VAR_0232884
    ----see VAR_0232882 G D mis40--------
    rs172289321,2
    C,F--115593993(-) GTGACAA/-GAGAT 2 -- ds50011Minor allele frequency- -:0.01NS 168
    rs1893674141,2
    --115594092(+) TCTACC/TCAACT 2 -- ds50010--------
    rs1813071281,2
    --115594141(+) TGGGCC/TGGGTG 2 -- ds50010--------
    rs172289181,2
    C,F,H--115594147(-) CCACCG/ACACCC 2 -- ds50014Minor allele frequency- A:0.14NS NA 456
    rs172353391,2
    C,F--115594229(-) TGTTGG/ACCAGG 2 -- ds50011Minor allele frequency- A:0.02NS 176
    rs1418962371,2
    --115594362(+) GGAGGC/TTGCAG 2 -- ds50010--------
    rs1472698411,2
    --115594384(+) ACTACA/GGCCCA 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for DCLRE1A (115594484 - 115614142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DCLRE1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv507578CNV Insertion20534489
    nsv896016CNV Loss21882294
    nsv831995CNV Gain+Loss17160897
    nsv7211OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609682    OMIM disorders: --

    3 diseases for DCLRE1A:    About MalaCards
    fanconi's anemia    alzheimer's disease    anemia

    1 disease from the University of Copenhagen DISEASES database for DCLRE1A:
    Fanconi's anemia

    DCLRE1A for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): DCLRE1A
    Human Genome Epidemiology (HuGE) Navigator: DCLRE1A (2 documents)

    Export disorders for DCLRE1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DCLRE1A gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with DCLRE1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. (PubMed id 10848582)1, 2, 9 Dronkert M.L.G.... Kanaar R. (2000)
    2. Genomic organization of a potential human DNA-crosslink repair gene, KIAA0086. (PubMed id 9806498)1, 3, 9 Demuth I. and Digweed M. (1998)
    3. The hSNM1 protein is a DNA 5'-exonuclease. (PubMed id 17804464)1, 3, 9 Hejna J....Moses R. (2007)
    4. hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. (PubMed id 12446782)1, 2, 9 Richie C.T....Legerski R.J. (2002)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    6. DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation. (PubMed id 15572677)1, 2 Ishiai M....Takata M. (2004)
    7. Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. (PubMed id 15542852)1, 2 Akhter S.... Legerski R.J. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    10. Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. (PubMed id 12509242)1, 2 Zhang X.... Legerski R.J. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9937 HGNC: 17660 AceView: DCLRE1A Ensembl:ENSG00000198924 euGenes: HUgn9937
    ECgene: DCLRE1A H-InvDB: DCLRE1A

    (According to HUGE)
    About This Section
    HUGE: KIAA0086

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DCLRE1A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DCLRE1A Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/dclre1a/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DCLRE1A gene:
    Search GeneIP for patents involving DCLRE1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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