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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DCLRE1A Gene

protein-coding   GIFtS: 56
GCID: GC10M115584

DNA cross-link repair 1A

(Previous names: DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)...)
 Explore 4 diseases affiliated with
DCLRE1A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DCLRE1A    

Aliases
for DCLRE1A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
DNA Cross-Link Repair 1A1 2     SNM1 Homolog A2 3
SNM11 2 3 5     DNA Cross-Link Repair 1A (PSO2 Homolog, S. Cerevisiae)1
KIAA00861 3 5     DNA Cross-Link Repair 1A Protein2
SNM1A2 3 5     DNA-Crosslink Repair Gene SNM12
PSO21 2     HSNM1A1
HSNM11     

External Ids:    HGNC: 176601   Entrez Gene: 99372   Ensembl: ENSG000001989247   OMIM: 6096825   UniProtKB: Q6PJP83   

Export aliases for DCLRE1A gene to outside databases

Previous GC identifers: GC10M114501 GC10M114828 GC10M115725 GC10M115259 GC10M109221


Summaries
for DCLRE1A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for DCLRE1A:
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links
suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle
checkpoint. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
arrest in early prophase in response to mitotic spindle poisons

Gene Wiki entry for DCLRE1A


Genomic Views
for DCLRE1A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DCLRE1A gene promoter:
         E2F-4   E2F-3a   AML1a   p53   E2F-2   CREB   E2F   E2F-1   HSF2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DCLRE1A promoter sequence
   Search SABiosciences Chromatin IP Primers for DCLRE1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCLRE1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.1   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q25.1

DCLRE1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCLRE1A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M115584:  view genomic region     (about GC identifiers)

Start:
 115,594,484 bp from pter      End:
 115,614,142 bp from pter
Size:
 19,659 bases      Orientation:
 minus strand

Proteins
for DCLRE1A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8 (See protein sequence)
Recommended Name: DNA cross-link repair 1A protein  
Size: 1040 amino acids; 116400 Da
Subunit: Binds constitutively to TP53BP1. Binds CDC27, which is itself a component of the anaphase promoting complex
(APC). Binds PIAS1
Subcellular location: Nucleus. Note=In some cells it may be found in typically 1 or 2 discrete nuclear aggregates of
unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in number
following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with those formed
by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1
Sequence caution: Sequence=BAA07646.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for DCLRE1A:
4B87 (3D)    
Secondary accessions: D3DRC1 Q14701 Q6P5Y3 Q6PKL4

Explore the universe of human proteins at neXtProt for DCLRE1A: NX_Q6PJP8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6PJP8

    • DCLRE1A Protein expression data from MOPED and PaxDb:    About this image 
    DCLRE1A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001258745.1  NP_055696.3  

    ENSEMBL proteins: 
     ENSP00000358311   ENSP00000355185  

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    Uscn Proteins for DCLRE1A

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    DCLRE1A for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for DCLRE1A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DCLRE1A for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR011084 DRMBL
     IPR001279 Beta-lactamas-like

    Graphical View of Domain Structure for InterPro Entry Q6PJP8

    ProtoNet protein and cluster: Q6PJP8

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Similarity: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family


    Function
    for DCLRE1A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCR1A_HUMAN, Q6PJP8
    Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle
    arrest in early prophase in response to mitotic spindle poisons
    Induction: During mitosis. The mRNA encoding this protein contains an internal ribosome entry site (IRES) in its
    5'-UTR. This 5'-UTR generally suppresses translation while specifically promoting expression during mitosis, when
    cap-dependent translation may be impaired

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
         
    DCLRE1A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DCLRE1A:
     Increased circadian period len  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Dclre1a):
     cellular  homeostasis/metabolism  immune system  mortality/aging  tumorigenesis 

    DCLRE1A for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-outs for DCLRE1A: Dclre1atm1Remo Dclre1atm1Rleg Dclre1atm1Roka
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DCLRE1A 

    miRNA
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    hsa-miR-3163 hsa-miR-133a hsa-miR-155 hsa-miR-590-3p hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmid: DCLRE1A 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCLRE1A


    Pathways & Interactions
    for DCLRE1A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Chks in Checkpoint Regulation
    		DNA Repair Mechanisms0.32

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for DCLRE1A
        DNA Repair Mechanisms


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DCLRE1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for DCLRE1A (Q6PJP83 ENSP000003551854) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIAS1O759253, ENSP000002496364I2D: score=2 STRING: ENSP00000249636
    ATMQ133153, ENSP000002786164I2D: score=1 STRING: ENSP00000278616
    TP53BP1Q128883, ENSP000003714754I2D: score=1 STRING: ENSP00000371475
    UBCENSP000003448184STRING: ENSP00000344818
    PCNAENSP000003684384STRING: ENSP00000368438
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006289nucleotide-excision repair IEA--
    GO:0007067mitosis IEA--
    GO:0051301cell division IEA--

    DCLRE1A for ontologies           About GeneDecksing



    Drugs & Compounds
    for DCLRE1A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DCLRE1A
    Search CenterWatch for drugs/clinical trials and news about DCLRE1A / DCR1A 

    Transcripts
    for DCLRE1A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DCLRE1A gene (2 alternative transcripts): 
    NM_001271816.1  NM_014881.4  

    Unigene Cluster for DCLRE1A:

    DNA cross-link repair 1A
    Hs.1560  [show with all ESTs]
    Unigene Representative Sequence: NM_014881
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369305 ENST00000361384(uc001law.2) ENST00000476112

    miRNA
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    hsa-miR-3163 hsa-miR-133a hsa-miR-155 hsa-miR-590-3p hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmid: DCLRE1A 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCLRE1A (see all 7)
    OriGene shRNA RFP: DCLRE1A
    OriGene siRNA: DCLRE1A
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    Sirion Biotech Custom design and validation of potent shRNA sequences against DCLRE1A 
    Clone
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    Primer
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    Additional cDNA sequence: 

    AK307187.1 BC013124.2 BC062582.1 D42045.1 

    3 DOTS entries:

    DT.213619  DT.100020107  DT.301063 

    24/83 AceView cDNA sequences (see all 83):

    AA630074 AI682192 NM_014881 BU623158 N46162 AA860577 AL043226 BM698798 
    CB130234 AL360205 D42045 BC013124 BM703845 AI681848 BC062582 CB146751 
    BE671341 AI679517 AL700451 AI695881 CA489699 AI962459 AI243372 BX433249 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for DCLRE1A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                              
    SP2:        -                                                                     


    ECgene alternative splicing isoforms for DCLRE1A

    Expression
    for DCLRE1A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DCLRE1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCAGTTATA
    DCLRE1A Expression
    About this image

    DCLRE1A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobulePerivenous HepatocytesLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DCLRE1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DCLRE1A

    SOURCE GeneReport for Unigene cluster: Hs.1560

    UniProtKB/Swiss-Prot: DCR1A_HUMAN, Q6PJP8
    Tissue specificity: Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle

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    In Situ
    Assay Products:     
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    Orthologs
    for DCLRE1A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCLRE1A gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Dclre1a1 , 5 DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)1, 5 73.29(n)1
    65.9(a)1    		   19 (51.89 cM)5
    559471  NM_018831.41  NP_061301.31 
     565291615 
    chicken
    (Gallus gallus)    		 Aves DCLRE1A1 DNA cross-link repair 1A 59.66(n)
    51.03(a)    		   423902  NM_001008683.1  NP_001008683.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DCLRE1A6
    		 --
    		 42(a)
    		 1 ↔ 1
    		 GL343204.1(525444-544281)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.256382 Xenopus laevis transcribed sequence with weak similarity more 73.73(n)    BU913862.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufc49f052 Transcribed sequence with weak similarity to protein more 80.28(n)    BM777630.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Snm13 DNA repair 37(a)   83B1   --
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SNM11 DNA cross-link repair protein SNM1 51.87(n)
    47.26(a)    		   822280  NM_113579.2  NP_189302.1 
    rice
    (Oryza sativa)    		 Liliopsida Os04g04018001 hypothetical protein 48.41(n)
    44.09(a)    		   4335730  NM_001059225.1  NP_001052690.1 


    ENSEMBL Gene Tree for DCLRE1A (if available)
    TreeFam Gene Tree for DCLRE1A (if available) 

    Paralogs
    for DCLRE1A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DCLRE1A gene
    DCLRE1B2  DCLRE1C2  

    DCLRE1A for paralogs           About GeneDecksing



    Genomic Variants
    for DCLRE1A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/407 NCBI SNPs in DCLRE1A are shown (see all 407)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs172289321,2
    		C,F--115593993(-) GTGACAA/-GAGAT 1 -- ds50011Minor allele frequency- -:0.01NS 168
    rs1893674141,2
    		--115594092(+) TCTACC/TCAACT 1 -- ds50010--------
    rs1813071281,2
    		--115594141(+) TGGGCC/TGGGTG 1 -- ds50010--------
    rs172289181,2
    		C,F,H--115594147(-) CCACCG/ACACCC 1 -- ds50014Minor allele frequency- A:0.14NS NA 456
    rs172353391,2
    		C,F--115594229(-) TGTTGG/ACCAGG 1 -- ds50011Minor allele frequency- A:0.02NS 176
    rs1418962371,2
    		--115594362(+) GGAGGC/TTGCAG 1 -- ds50010--------
    rs1472698411,2
    		--115594384(+) ACTACA/GGCCCA 1 -- ds50010--------
    rs1849241391,2
    		--115594516(+) ATACAC/TGTCAT 1 -- ut310--------
    rs172353251,2
    		C--115594589(-) TTAATA/GAAGTA 1 -- ut311Minor allele frequency- G:0.01NS 172
    rs1407606881,2
    		--115594637(+) CTTCCC/TCTTCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DCLRE1A (115594484 - 115614142 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DCLRE1A: --

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    Disorders / Diseases
    for DCLRE1A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DCLRE1A for disorders           About GeneDecksing

    OMIM gene information: 609682    OMIM disorders: --

    4 diseases for DCLRE1A:    About MalaCards
    alzheimer's disease    lung carcinoma    carcinoma    malaria

    1 disease from the University of Copenhagen DISEASES database for DCLRE1A:
    Fanconi's anemia
    Human Genome Epidemiology (HuGE) Navigator: DCLRE1A (2 documents)

    Export disorders for DCLRE1A gene to outside databases

    Publications
    for DCLRE1A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DCLRE1A gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with DCLRE1A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. (PubMed id 10848582)1, 2, 9 Dronkert M.L.G.... Kanaar R. (2000)
    2. Genomic organization of a potential human DNA-crosslink repair gene, KIAA0086. (PubMed id 9806498)1, 3, 9 Demuth I. and Digweed M. (1998)
    3. The hSNM1 protein is a DNA 5'-exonuclease. (PubMed id 17804464)1, 3, 9 Hejna J....Moses R. (2007)
    4. hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. (PubMed id 12446782)1, 2, 9 Richie C.T....Legerski R.J. (2002)
    5. DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation. (PubMed id 15572677)1, 2 Ishiai M....Takata M. (2004)
    6. Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. (PubMed id 15542852)1, 2 Akhter S.... Legerski R.J. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    9. Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. (PubMed id 12509242)1, 2 Zhang X.... Legerski R.J. (2002)
    10. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2 Nagase T....Kotani H. (1995)

    External Searches for DCLRE1A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DCLRE1A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9937 HGNC: 17660 AceView: DCLRE1A Ensembl:ENSG00000198924 euGenes: HUgn9937
    ECgene: DCLRE1A H-InvDB: DCLRE1A

    Other Databases showing DCLRE1A gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0086

    Specialized Databases showing DCLRE1A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DCLRE1A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DCLRE1A Genetics and Cytogenetics in Oncology and Haematology
    NIEHS-SNPshttp://egp.gs.washington.edu/data/dclre1a/

    Intellectual Property
    for DCLRE1A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DCLRE1A gene:
    Search GeneIP for patents involving DCLRE1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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