Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DCDC5 Gene

protein-coding GIFtS: 43
GCID: GC11M030809

doublecortin domain containing 5

Search for DCDC5
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Doublecortin Domain Containing 5¹ ²
KIAA1493³ ⁵
FLJ46154¹
Doublecortin Domain-Containing Protein 5²

External Ids:	HGNC: 24799¹	Entrez Gene: 100506627²	Ensembl: ENSG00000170959⁷	OMIM: 612321⁵	UniProtKB: Q6ZRR9³

Export aliases for DCDC5 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DCDC5:

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin

domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization.

Alternatively spliced transcript variants encoding distinct isoforms have been found, but the full-length nature of

some variants is not determined. (provided by RefSeq, Feb 2011)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DCDC5 gene promoter:
LHX3b/Lhx3b POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) Cdc5 POU3F2 Arnt E47 POU2F1 POU2F1a LHX3a/Lhx3a
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for DCDC5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCDC5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p14.1 Ensembl cytogenetic band: 11p13 HGNC cytogenetic band: 11p14.1

DCDC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCDC5 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M030809: view genomic region (about GC identifiers)

Start:	30,851,916 bp from pter	End:	31,149,212 bp from pter
Size:	297,297 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DCDC5_HUMAN, Q6ZRR9 (See protein sequence)

Recommended Name: Doublecortin domain-containing protein 5

Size: 648 amino acids; 72753 Da

Sequence caution: Sequence=BAC87240.1; Type=Miscellaneous discrepancy; Sequence=CAO03425.1; Type=Erroneous gene model

prediction;

Secondary accessions: B1AL47

Explore the universe of human proteins at neXtProt for DCDC5: NX_Q6ZRR9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZRR9

DCDC5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065920.2

ENSEMBL proteins:

ENSP00000404672 ENSP00000306898 ENSP00000401912 ENSP00000385936 ENSP00000341700

Human Recombinant Protein Products for DCDC5:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for DCDC5
	GenScript Custom Purified and Recombinant Proteins Services for DCDC5
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DCDC5

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--

DCDC5 for ontologies About GeneDecksing

DCDC5 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for DCDC5
	GenScript Custom Superior Antibodies Services for DCDC5
	Novus Biologicals DCDC5 Antibody
	Search for Antibodies for DCDC5 at Abcam
	Uscn Antibodies for DCDC5
	Search ThermoFisher Antibodies for DCDC5

Assay Products for DCDC5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for DCDC5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for DCDC5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DCDC5 for domains About GeneDecksing

2 InterPro domains/families:

IPR000772 Ricin_B_lectin

IPR003533 Doublecortin_dom

Graphical View of Domain Structure for InterPro Entry Q6ZRR9

ProtoNet protein and cluster: Q6ZRR9

1 Blocks protein family: IPB000772 Ricin B lectin domain

UniProtKB/Swiss-Prot: DCDC5_HUMAN, Q6ZRR9

Similarity: Contains 2 doublecortin domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for DCDC5:

Decreased homologous recombina

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DCDC5

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCDC5
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate DCDC5 (see all 12):
		hsa-miR-299-5p hsa-miR-579 hsa-miR-3132 hsa-miR-130a* hsa-miR-146a hsa-miR-23c hsa-miR-146a* hsa-miR-3199

		SwitchGear 3'UTR luciferase reporter plasmid: DCDC5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCDC5 (see all 6) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCDC5
		Sirion Biotech Custom design and validation of potent shRNA sequences against DCDC5

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for DCDC5
			Sirion Biotech Customized adenovirus for overexpression of DCDC5 Sirion Biotech Customized adenovirus for potent knockdown of DCDC5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCDC5 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 9): DCDC5 (XM_003119485)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCDC5
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DCDC5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DCDC5
		Search LifeMap BioReagents cell lines for DCDC5
		Sirion Biotech Customized stable knockdown cell line services for DCDC5 Sirion Biotech Customized inducible knockdown cell line services for DCDC5 Sirion Biotech Customized stable overexpressing cell line services for DCDC5 Sirion Biotech Customized inducible overexpressing cell line services for DCDC5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC5

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DCDC5

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0035556	intracellular signal transduction	IEA	--

DCDC5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DCDC5
Search CenterWatch for drugs/clinical trials and news about DCDC5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DCDC5 gene (2 alternative transcripts):

NM_198462.2 NM_020869.3

Unigene Cluster for DCDC5:

Doublecortin domain containing 5

Hs.530438 [show with all ESTs]

Unigene Representative Sequence: NM_020869

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000444572(uc001mss.1) ENST00000303697(uc009yjj.2) ENST00000483396(uc021qfk.1 uc009yjk.1)

ENST00000429306 ENST00000437348(uc009yjl.1) ENST00000406071 ENST00000339794

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCDC5
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate DCDC5 (see all 12):
		hsa-miR-299-5p hsa-miR-579 hsa-miR-3132 hsa-miR-130a* hsa-miR-146a hsa-miR-23c hsa-miR-146a* hsa-miR-3199

		SwitchGear 3'UTR luciferase reporter plasmid: DCDC5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCDC5 (see all 6) Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCDC5
		Sirion Biotech Custom design and validation of potent shRNA sequences against DCDC5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCDC5 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 9): DCDC5 (XM_003119485)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCDC5
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DCDC5

Primer Products:		Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat DCDC5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCDC5
		Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC5

4 DOTS entries:

DT.430080 DT.101978078 DT.92013273 DT.307316

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for DCDC5 About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	^	13	^	14	^	15	^	16	^	17	^	18
SP1:																					-				-
SP2:
SP3:

ECgene alternative splicing isoforms for DCDC5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DCDC5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

DCDC5 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Dorsal Columns

Dorsal Spinal Cord Progenitor Cells

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Neural Tube

Spinal Dorsal Columns

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See DCDC5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DCDC5

SOURCE GeneReport for Unigene cluster: Hs.530438

SABiosciences Custom PCR Arrays for DCDC5

Primer Products:		Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat DCDC5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCDC5
		Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for DCDC5 gene from 2/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dcdc5^{1 , 5}	doublecortin domain containing 5^{1, 5}	76.55(n)¹ 66.93(a)¹		2 (55.58 cM)⁵ 329482¹ XM_001481324.3¹ XP_001481374.3¹ 106222057⁵
lizard (Anolis carolinensis)	Reptilia	DCDC1⁶	--	58(a)	1 ↔ 1	1(60256746-60278336)

ENSEMBL Gene Tree for DCDC5 (if available)
TreeFam Gene Tree for DCDC5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144768516^1,2		--	30884718(+)	`CTGAAC/TGCTTG`	1	--	int¹		0	--	--	--	--
rs147897249^1,2		--	30884798(+)	`AACCCA/CAGGTG`	1	--	int¹		0	--	--	--	--
rs141578424^1,2		--	30884943(+)	`GGAAAA/GCAGTA`	1	--	int¹		0	--	--	--	--
rs190935538^1,2		--	30885238(+)	`GACGCA/GTATTT`	1	--	ut3¹		0	--	--	--	--
rs142811123^1,2		--	30885254(+)	`TCATCC/TATTTG`	1	--	ut3¹		0	--	--	--	--
rs183080038^1,2		--	30885301(+)	`TTATGA/GAAATG`	1	--	ut3¹		0	--	--	--	--
rs187963223^1,2		--	30885535(+)	`TGGGTA/GTGGTG`	1	--	ut3¹		0	--	--	--	--
rs190649641^1,2		--	30885766(+)	`GAACTC/GCTTCA`	1	--	ut3¹		0	--	--	--	--
rs117664167^1,2	F	--	30885783(+)	`CCTGTC/TGAAGT`	1	--	ut3¹		1		EA	120
rs151028349^1,2		--	30885791(+)	`AGTCTC/GAAATG`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DCDC5 (30851916 - 31101916 bp, first 250kb of DCDC5)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for DCDC5: --

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCDC5

DNA2.0 Custom Variant and Variant Library Synthesis for DCDC5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DCDC5 for disorders About MalaCards

DCDC5 for disorders About GeneDecksing

OMIM gene information: 612321 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: DCDC5 (3 documents)

Export disorders for DCDC5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DCDC5 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with DCDC5)

Utopia: connect your pdf to the dynamic
world of online information

The evolving doublecortin (DCX) superfamily. (PubMed id 16869982)^{1, 3} Reiner O....Bergmann S. (2006)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)^{1, 2} Taylor T.D....Sakaki Y. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. (PubMed id 22797727)¹ Okada Y....Tanaka T. (2012)
Linking cytoplasmic dynein and transport of Rab8 vesic les to the midbody during cytokinesis by the doublecortin domain-containing 5 pr otein. (PubMed id 22159412)¹ Kaplan A. and Reiner O. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The doublecortin gene family and disorders of neurona l structure. (PubMed id 20236041)¹ Dijkmans T.F....Vreugdenhil E. (2010)
Genome-wide association studies of serum magnesium, p otassium, and sodium concentrations identify six Loci influencing serum magnesi um levels. (PubMed id 20700443)¹ Meyer T.E.... . (2010)
Twenty bone-mineral-density loci identified by large- scale meta-analysis of genome-wide association studies. (PubMed id 19801982)¹ Rivadeneira F....Uitterlinden A.G. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 100506627	HGNC: 24799	Ensembl:ENSG00000170959	euGenes: HUgn100506627	ECgene: DCDC5
H-InvDB: DCDC5

(According to HUGE)
About This Section

HUGE: KIAA1493

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DCDC5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DCDC5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DCDC5 gene:
Search GeneIP for patents involving DCDC5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCDC5		Browse OriGene genome-wide validated SYBR primer pairs
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	Browse OriGene siRNAs		Browse 3'-UTR reporter clones for miRNA target validation
	Browse OriGene untagged cDNA clones in CMV expression vector		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCDC5
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for DCDC5		OriGene Custom Protein Services for DCDC5
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DCDC5
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCDC5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCDC5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCDC5
	Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC5
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCDC5

	GenScript Custom Purified and Recombinant Proteins Services for DCDC5		GenScript cDNA clones with any tag delivered in your preferred vector for DCDC5
	GenScript Custom Assay Services for DCDC5		GenScript Custom Superior Antibodies Services for DCDC5
	GenScript Custom overexpressing Cell Line Services for DCDC5		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in DCDC5 promoter
	Search Chromatin IP Primers for DCDC5
	RT² qPCR Primer Assay in human, mouse / rat DCDC5
	Search GNC Networks for DCDC5
	SABiosciences Custom PCR Arrays for DCDC5

Search Tocris compounds for DCDC5

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	DCDC5 antibodies

	Search for Antibodies for DCDC5 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for DCDC5
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

DCDC5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for DCDC5

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC5

	SwitchGear 3'UTR luciferase reporter plasmids for DCDC5
	Browse SwitchGear Promoter luciferase reporter plasmids for DCDC5

Search ThermoFisher Antibodies for DCDC5

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat DCDC5

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DCDC5

Sirion Biotech Customized:

	stable knockdown cell line services for DCDC5
	inducible knockdown cell line services for DCDC5
	design and validation of potent shRNA sequences against DCDC5
	adenovirus for potent knockdown of DCDC5
	adenovirus for overexpression of DCDC5
	stable overexpressing cell line services for DCDC5
	inducible overexpressing cell line services for DCDC5

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes DCDC5 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

DCDC5 Gene

doublecortin domain containing 5

Aliases
for DCDC5 gene

Summaries
for DCDC5 gene

Genomic Views
for DCDC5 gene

Proteins
for DCDC5 gene

Protein Domains /
Families
for DCDC5 gene

Function
for DCDC5 gene

Pathways & Interactions
for DCDC5 gene

Drugs & Compounds
for DCDC5 gene

Transcripts
for DCDC5 gene

Expression
for DCDC5 gene

Orthologs
for DCDC5 gene

Paralogs
for DCDC5 gene

Genomic Variants
for DCDC5 gene

Disorders / Diseases
for DCDC5 gene

Publications
for DCDC5 gene

External Searches for DCDC5 gene

Genome Databases showing DCDC5 gene

Other Databases showing DCDC5 gene

Specialized Databases showing DCDC5 gene

Intellectual Property
for DCDC5 gene

Products
for DCDC5 gene

View Random Gene

Advanced Search

Export list of displayed genes

DCDC5 Gene

doublecortin domain containing 5

Aliasesfor DCDC5 gene

Summariesfor DCDC5 gene

Genomic Viewsfor DCDC5 gene

Proteinsfor DCDC5 gene

Protein Domains /Familiesfor DCDC5 gene

Functionfor DCDC5 gene

Pathways & Interactionsfor DCDC5 gene

Drugs & Compoundsfor DCDC5 gene

Transcriptsfor DCDC5 gene

Expression for DCDC5 gene

Orthologsfor DCDC5 gene

Paralogsfor DCDC5 gene

Genomic Variantsfor DCDC5 gene

Disorders / Diseasesfor DCDC5 gene

Publicationsfor DCDC5 gene

External Searches for DCDC5 gene

Genome Databases showing DCDC5 gene

Other Databases showing DCDC5 gene

Specialized Databases showing DCDC5 gene

Intellectual Propertyfor DCDC5 gene

Productsfor DCDC5 gene

View Random Gene

Aliases
for DCDC5 gene

Summaries
for DCDC5 gene

Genomic Views
for DCDC5 gene

Proteins
for DCDC5 gene

Protein Domains /
Families
for DCDC5 gene

Function
for DCDC5 gene

Pathways & Interactions
for DCDC5 gene

Drugs & Compounds
for DCDC5 gene

Transcripts
for DCDC5 gene

Expression
for DCDC5 gene

Orthologs
for DCDC5 gene

Paralogs
for DCDC5 gene

Genomic Variants
for DCDC5 gene

Disorders / Diseases
for DCDC5 gene

Publications
for DCDC5 gene

Intellectual Property
for DCDC5 gene

Products
for DCDC5 gene